

<!--XBRL Document Created with Wdesk from Workiva-->
<!-- -->
<link:linkbase xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd" xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
  <link:roleRef roleURI="http://www.endo.com/role/AccountsPayableAndAccruedExpenses" xlink:href="endp-20190930.xsd#AccountsPayableAndAccruedExpenses" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/AccountsPayableAndAccruedExpensesDetails" xlink:href="endp-20190930.xsd#AccountsPayableAndAccruedExpensesDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/AccountsPayableAndAccruedExpensesTables" xlink:href="endp-20190930.xsd#AccountsPayableAndAccruedExpensesTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/BasisOfPresentation" xlink:href="endp-20190930.xsd#BasisOfPresentation" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/CommitmentsAndContingencies" xlink:href="endp-20190930.xsd#CommitmentsAndContingencies" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/CommitmentsAndContingenciesNarrativeDetails" xlink:href="endp-20190930.xsd#CommitmentsAndContingenciesNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/CommitmentsAndContingenciesScheduleOfLossContingenciesDetails" xlink:href="endp-20190930.xsd#CommitmentsAndContingenciesScheduleOfLossContingenciesDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/CommitmentsAndContingenciesTables" xlink:href="endp-20190930.xsd#CommitmentsAndContingenciesTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/CondensedConsolidatedBalanceSheetsUnaudited" xlink:href="endp-20190930.xsd#CondensedConsolidatedBalanceSheetsUnaudited" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/CondensedConsolidatedBalanceSheetsUnauditedParenthetical" xlink:href="endp-20190930.xsd#CondensedConsolidatedBalanceSheetsUnauditedParenthetical" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/CondensedConsolidatedStatementsOfCashFlowsUnaudited" xlink:href="endp-20190930.xsd#CondensedConsolidatedStatementsOfCashFlowsUnaudited" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/CondensedConsolidatedStatementsOfComprehensiveLossUnaudited" xlink:href="endp-20190930.xsd#CondensedConsolidatedStatementsOfComprehensiveLossUnaudited" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/CondensedConsolidatedStatementsOfOperationsUnaudited" xlink:href="endp-20190930.xsd#CondensedConsolidatedStatementsOfOperationsUnaudited" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/ContractAssetsAndLiabilities" xlink:href="endp-20190930.xsd#ContractAssetsAndLiabilities" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/ContractAssetsAndLiabilitiesContractAssetsAndContractLiabilitiesFromContractsWithCustomersDetails" xlink:href="endp-20190930.xsd#ContractAssetsAndLiabilitiesContractAssetsAndContractLiabilitiesFromContractsWithCustomersDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/ContractAssetsAndLiabilitiesNarrativeDetails" xlink:href="endp-20190930.xsd#ContractAssetsAndLiabilitiesNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/ContractAssetsAndLiabilitiesTables" xlink:href="endp-20190930.xsd#ContractAssetsAndLiabilitiesTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/CoverPage" xlink:href="endp-20190930.xsd#CoverPage" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/Debt" xlink:href="endp-20190930.xsd#Debt" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/DebtComponentsOfTotalIndebtednessDetails" xlink:href="endp-20190930.xsd#DebtComponentsOfTotalIndebtednessDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/DebtCreditFacilityNarrativeDetails" xlink:href="endp-20190930.xsd#DebtCreditFacilityNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/DebtMarch2019RefinancingDetails" xlink:href="endp-20190930.xsd#DebtMarch2019RefinancingDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/DebtMaturitiesOnLongTermDebtForEachOfNextFiveYearsDetails" xlink:href="endp-20190930.xsd#DebtMaturitiesOnLongTermDebtForEachOfNextFiveYearsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/DebtTables" xlink:href="endp-20190930.xsd#DebtTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/DiscontinuedOperations" xlink:href="endp-20190930.xsd#DiscontinuedOperations" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/DiscontinuedOperationsAstoraDiscontinuedOperationsDetails" xlink:href="endp-20190930.xsd#DiscontinuedOperationsAstoraDiscontinuedOperationsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/DiscontinuedOperationsAstoraNarrativeDetails" xlink:href="endp-20190930.xsd#DiscontinuedOperationsAstoraNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/DiscontinuedOperationsTables" xlink:href="endp-20190930.xsd#DiscontinuedOperationsTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/FairValueMeasurements" xlink:href="endp-20190930.xsd#FairValueMeasurements" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/FairValueMeasurementsFinancialAssetsAndLiabilitiesMeasuredAtFairValueOnRecurringBasisDetails" xlink:href="endp-20190930.xsd#FairValueMeasurementsFinancialAssetsAndLiabilitiesMeasuredAtFairValueOnRecurringBasisDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/FairValueMeasurementsFinancialLiabilitiesMeasuredAtFairValueOnRecurringBasisUsingSignificantUnobservableInputsDetails" xlink:href="endp-20190930.xsd#FairValueMeasurementsFinancialLiabilitiesMeasuredAtFairValueOnRecurringBasisUsingSignificantUnobservableInputsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/FairValueMeasurementsNarrativeDetails" xlink:href="endp-20190930.xsd#FairValueMeasurementsNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/FairValueMeasurementsRestrictedCashAndCashEquivalentsDetails" xlink:href="endp-20190930.xsd#FairValueMeasurementsRestrictedCashAndCashEquivalentsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/FairValueMeasurementsScheduleOfFinancialAssetsMeasuredAtFairValueOnNonrecurringBasisDetails" xlink:href="endp-20190930.xsd#FairValueMeasurementsScheduleOfFinancialAssetsMeasuredAtFairValueOnNonrecurringBasisDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/FairValueMeasurementsTables" xlink:href="endp-20190930.xsd#FairValueMeasurementsTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/GoodwillAndOtherIntangibles" xlink:href="endp-20190930.xsd#GoodwillAndOtherIntangibles" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/GoodwillAndOtherIntangiblesAccumulatedImpairmentDetails" xlink:href="endp-20190930.xsd#GoodwillAndOtherIntangiblesAccumulatedImpairmentDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/GoodwillAndOtherIntangiblesImpairmentsNarrativeDetails" xlink:href="endp-20190930.xsd#GoodwillAndOtherIntangiblesImpairmentsNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/GoodwillAndOtherIntangiblesOtherIntangiblesNarrativeDetails" xlink:href="endp-20190930.xsd#GoodwillAndOtherIntangiblesOtherIntangiblesNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/GoodwillAndOtherIntangiblesScheduleOfChangesInCarryingAmountOfGoodwillDetails" xlink:href="endp-20190930.xsd#GoodwillAndOtherIntangiblesScheduleOfChangesInCarryingAmountOfGoodwillDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/GoodwillAndOtherIntangiblesScheduleOfEstimatedAmortizationOfIntangiblesDetails" xlink:href="endp-20190930.xsd#GoodwillAndOtherIntangiblesScheduleOfEstimatedAmortizationOfIntangiblesDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/GoodwillAndOtherIntangiblesScheduleOfIntangibleAssetImpairmentChargesIncludingGoodwillDetails" xlink:href="endp-20190930.xsd#GoodwillAndOtherIntangiblesScheduleOfIntangibleAssetImpairmentChargesIncludingGoodwillDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/GoodwillAndOtherIntangiblesScheduleOfOtherIntangibleAssetsDetails" xlink:href="endp-20190930.xsd#GoodwillAndOtherIntangiblesScheduleOfOtherIntangibleAssetsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/GoodwillAndOtherIntangiblesTables" xlink:href="endp-20190930.xsd#GoodwillAndOtherIntangiblesTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/IncomeTaxes" xlink:href="endp-20190930.xsd#IncomeTaxes" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/IncomeTaxesScheduleOfComponentsOfContinuingOperationsBeforeIncomeTaxIncomeTaxExpenseEffectiveTaxRateDetails" xlink:href="endp-20190930.xsd#IncomeTaxesScheduleOfComponentsOfContinuingOperationsBeforeIncomeTaxIncomeTaxExpenseEffectiveTaxRateDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/IncomeTaxesTables" xlink:href="endp-20190930.xsd#IncomeTaxesTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/Inventories" xlink:href="endp-20190930.xsd#Inventories" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/InventoriesDetails" xlink:href="endp-20190930.xsd#InventoriesDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/InventoriesTables" xlink:href="endp-20190930.xsd#InventoriesTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/Leases" xlink:href="endp-20190930.xsd#Leases" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/LeasesAssetsAndLiabilitiesDetails" xlink:href="endp-20190930.xsd#LeasesAssetsAndLiabilitiesDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/LeasesCashFlowAndSupplementalNoncashInformationDetails" xlink:href="endp-20190930.xsd#LeasesCashFlowAndSupplementalNoncashInformationDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/LeasesComponentsOfLeaseExpenseDetails" xlink:href="endp-20190930.xsd#LeasesComponentsOfLeaseExpenseDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/LeasesFutureMinimumLeasePaymentObligationsUnderOperatingAndCapitalLeasesDetails" xlink:href="endp-20190930.xsd#LeasesFutureMinimumLeasePaymentObligationsUnderOperatingAndCapitalLeasesDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/LeasesMaturitiesOfOperatingAndFinanceLeaseLiabilitiesDetails" xlink:href="endp-20190930.xsd#LeasesMaturitiesOfOperatingAndFinanceLeaseLiabilitiesDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/LeasesNarrativeDetails" xlink:href="endp-20190930.xsd#LeasesNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/LeasesTables" xlink:href="endp-20190930.xsd#LeasesTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/LeasesWeightedAverageTermLeaseAndDiscountRatesDetails" xlink:href="endp-20190930.xsd#LeasesWeightedAverageTermLeaseAndDiscountRatesDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/NetLossPerShare" xlink:href="endp-20190930.xsd#NetLossPerShare" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/NetLossPerShareReconciliationOfNumeratorAndDenominatorOfBasicAndDilutedNetLossPerShareDetails" xlink:href="endp-20190930.xsd#NetLossPerShareReconciliationOfNumeratorAndDenominatorOfBasicAndDilutedNetLossPerShareDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/NetLossPerShareTables" xlink:href="endp-20190930.xsd#NetLossPerShareTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/OtherComprehensiveIncomeLoss" xlink:href="endp-20190930.xsd#OtherComprehensiveIncomeLoss" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/OtherComprehensiveLossNarrativeDetails" xlink:href="endp-20190930.xsd#OtherComprehensiveLossNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/OtherExpenseIncomeNet" xlink:href="endp-20190930.xsd#OtherExpenseIncomeNet" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/OtherExpenseIncomeNetDetails" xlink:href="endp-20190930.xsd#OtherExpenseIncomeNetDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/OtherExpenseIncomeNetTables" xlink:href="endp-20190930.xsd#OtherExpenseIncomeNetTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/Restructuring" xlink:href="endp-20190930.xsd#Restructuring" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/Restructuring2017RestructuringInitiativesNarrativeDetails" xlink:href="endp-20190930.xsd#Restructuring2017RestructuringInitiativesNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/RestructuringJanuary2018RestructuringInitiativeNarrativeDetails" xlink:href="endp-20190930.xsd#RestructuringJanuary2018RestructuringInitiativeNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/RestructuringScheduleOfRestructuringRollForwardDetails" xlink:href="endp-20190930.xsd#RestructuringScheduleOfRestructuringRollForwardDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/RestructuringTables" xlink:href="endp-20190930.xsd#RestructuringTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/SegmentResults" xlink:href="endp-20190930.xsd#SegmentResults" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/SegmentResultsScheduleOfDisaggregationOfRevenuesDetails" xlink:href="endp-20190930.xsd#SegmentResultsScheduleOfDisaggregationOfRevenuesDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/SegmentResultsScheduleOfReconciliationsOfConsolidatedAdjustedIncomeLossBeforeIncomeTaxDetails" xlink:href="endp-20190930.xsd#SegmentResultsScheduleOfReconciliationsOfConsolidatedAdjustedIncomeLossBeforeIncomeTaxDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/SegmentResultsScheduleOfReportableSegmentsInformationDetails" xlink:href="endp-20190930.xsd#SegmentResultsScheduleOfReportableSegmentsInformationDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/SegmentResultsTables" xlink:href="endp-20190930.xsd#SegmentResultsTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/ShareholdersDeficit" xlink:href="endp-20190930.xsd#ShareholdersDeficit" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/ShareholdersDeficitEquityNarrativeDetails" xlink:href="endp-20190930.xsd#ShareholdersDeficitEquityNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/ShareholdersDeficitScheduleOfChangesInShareholdersEquityDetails" xlink:href="endp-20190930.xsd#ShareholdersDeficitScheduleOfChangesInShareholdersEquityDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/ShareholdersDeficitTables" xlink:href="endp-20190930.xsd#ShareholdersDeficitTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/SummaryOfSignificantAccountingPolicies" xlink:href="endp-20190930.xsd#SummaryOfSignificantAccountingPolicies" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/SummaryOfSignificantAccountingPoliciesNarrativeDetails" xlink:href="endp-20190930.xsd#SummaryOfSignificantAccountingPoliciesNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/SummaryOfSignificantAccountingPoliciesPolicies" xlink:href="endp-20190930.xsd#SummaryOfSignificantAccountingPoliciesPolicies" xlink:type="simple" />
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedLabel" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedLabel" xlink:type="simple" />
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedNetLabel" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedNetLabel" xlink:type="simple" />
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedPeriodEndLabel" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedPeriodEndLabel" xlink:type="simple" />
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedPeriodStartLabel" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedPeriodStartLabel" xlink:type="simple" />
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedTerseLabel" xlink:type="simple" />
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedTotalLabel" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedTotalLabel" xlink:type="simple" />
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/netLabel" xlink:href="http://www.xbrl.org/lrr/role/net-2009-12-16.xsd#netLabel" xlink:type="simple" />
  <link:presentationLink xlink:role="http://www.endo.com/role/AccountsPayableAndAccruedExpenses" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AccountsPayableAndAccruedLiabilitiesCurrentAbstract" xlink:label="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesCurrentAbstract_292430EC8DE21B743EF669023CC4EA8E" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AccountsPayableAndAccruedLiabilitiesDisclosureTextBlock" xlink:label="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesDisclosureTextBlock_9862122E13966C21368F69023CC502B3" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesCurrentAbstract_292430EC8DE21B743EF669023CC4EA8E" xlink:to="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesDisclosureTextBlock_9862122E13966C21368F69023CC502B3" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/AccountsPayableAndAccruedExpensesDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AccountsPayableAndAccruedLiabilitiesCurrentAbstract" xlink:label="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesCurrentAbstract_F3800941114AC496CFCB69023BC40D78" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AccountsPayableTradeCurrent" xlink:label="loc_us-gaap_AccountsPayableTradeCurrent_B2D8C833048F4267A55B69023BC4D811" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesCurrentAbstract_F3800941114AC496CFCB69023BC40D78" xlink:to="loc_us-gaap_AccountsPayableTradeCurrent_B2D8C833048F4267A55B69023BC4D811" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_AccruedLiabilitiesReturnsAndAllowances" xlink:label="loc_endp_AccruedLiabilitiesReturnsAndAllowances_3330433F54E60AFD0BBB69023BC5E4EF" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesCurrentAbstract_F3800941114AC496CFCB69023BC40D78" xlink:to="loc_endp_AccruedLiabilitiesReturnsAndAllowances_3330433F54E60AFD0BBB69023BC5E4EF" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_AccruedLiabilitiesRebates" xlink:label="loc_endp_AccruedLiabilitiesRebates_3FF3FDC63D4FB062418D69023BC53750" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesCurrentAbstract_F3800941114AC496CFCB69023BC40D78" xlink:to="loc_endp_AccruedLiabilitiesRebates_3FF3FDC63D4FB062418D69023BC53750" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_AccruedLiabilitiesChargebacks" xlink:label="loc_endp_AccruedLiabilitiesChargebacks_4217A7D1594587CBDFE269023BC54D37" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesCurrentAbstract_F3800941114AC496CFCB69023BC40D78" xlink:to="loc_endp_AccruedLiabilitiesChargebacks_4217A7D1594587CBDFE269023BC54D37" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_InterestPayableCurrent" xlink:label="loc_us-gaap_InterestPayableCurrent_CFD8E56547531F739B6569023BC5AFBE" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesCurrentAbstract_F3800941114AC496CFCB69023BC40D78" xlink:to="loc_us-gaap_InterestPayableCurrent_CFD8E56547531F739B6569023BC5AFBE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AccruedEmployeeBenefitsCurrent" xlink:label="loc_us-gaap_AccruedEmployeeBenefitsCurrent_18C5F2FE736F6A1882E369023BC65B00" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesCurrentAbstract_F3800941114AC496CFCB69023BC40D78" xlink:to="loc_us-gaap_AccruedEmployeeBenefitsCurrent_18C5F2FE736F6A1882E369023BC65B00" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_AccruedRoyaltiesandOtherDistributionPartnerPayablesCurrent" xlink:label="loc_endp_AccruedRoyaltiesandOtherDistributionPartnerPayablesCurrent_5F2862E0E362CA3B4EC969023BC6F742" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesCurrentAbstract_F3800941114AC496CFCB69023BC40D78" xlink:to="loc_endp_AccruedRoyaltiesandOtherDistributionPartnerPayablesCurrent_5F2862E0E362CA3B4EC969023BC6F742" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationLiabilityCurrent" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationLiabilityCurrent_0F75668A9792CF9FF09769023BC6F9C8" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesCurrentAbstract_F3800941114AC496CFCB69023BC40D78" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationLiabilityCurrent_0F75668A9792CF9FF09769023BC6F9C8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OtherAccruedLiabilitiesCurrent" xlink:label="loc_us-gaap_OtherAccruedLiabilitiesCurrent_8B9B56F92C5573BDD10069023BC6F933" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesCurrentAbstract_F3800941114AC496CFCB69023BC40D78" xlink:to="loc_us-gaap_OtherAccruedLiabilitiesCurrent_8B9B56F92C5573BDD10069023BC6F933" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AccountsPayableAndAccruedLiabilitiesCurrent" xlink:label="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesCurrent_6A629E20FD24C95F0BB669023BC6F563" xlink:type="locator" />
    <link:presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesCurrentAbstract_F3800941114AC496CFCB69023BC40D78" xlink:to="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesCurrent_6A629E20FD24C95F0BB669023BC6F563" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/AccountsPayableAndAccruedExpensesTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AccountsPayableAndAccruedLiabilitiesCurrentAbstract" xlink:label="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesCurrentAbstract_C939E08133989867B70669023CD0E8A0" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfAccountsPayableAndAccruedLiabilitiesTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfAccountsPayableAndAccruedLiabilitiesTableTextBlock_109807C8785BC74B0C7269023CD0BD57" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesCurrentAbstract_C939E08133989867B70669023CD0E8A0" xlink:to="loc_us-gaap_ScheduleOfAccountsPayableAndAccruedLiabilitiesTableTextBlock_109807C8785BC74B0C7269023CD0BD57" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/BasisOfPresentation" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract" xlink:label="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_76136AB2E8905AEB8FA03FA0A729C3D5" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureTextBlock" xlink:label="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureTextBlock_4BEEC735FFAE587E97A4F6779B488E3F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_76136AB2E8905AEB8FA03FA0A729C3D5" xlink:to="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureTextBlock_4BEEC735FFAE587E97A4F6779B488E3F" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/CommitmentsAndContingencies" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_DB701D87534753F19260D2E29452BB59" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureTextBlock" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureTextBlock_5808D40BD05D538A9AD97CDF083B1EBB" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_DB701D87534753F19260D2E29452BB59" xlink:to="loc_us-gaap_CommitmentsAndContingenciesDisclosureTextBlock_5808D40BD05D538A9AD97CDF083B1EBB" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/CommitmentsAndContingenciesNarrativeDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_B8FE574951EA4F784B3924593347A894" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LossContingenciesTable" xlink:label="loc_us-gaap_LossContingenciesTable_66443E6A321F095C88572459334790C4" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_B8FE574951EA4F784B3924593347A894" xlink:to="loc_us-gaap_LossContingenciesTable_66443E6A321F095C88572459334790C4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_ProductOrServiceAxis" xlink:label="loc_srt_ProductOrServiceAxis_38D2ED1550C86763317B2459334CD303" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesTable_66443E6A321F095C88572459334790C4" xlink:to="loc_srt_ProductOrServiceAxis_38D2ED1550C86763317B2459334CD303" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_ProductsAndServicesDomain" xlink:label="loc_srt_ProductsAndServicesDomain_FA56CF86A21CE8E0099C2459334CB382" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductOrServiceAxis_38D2ED1550C86763317B2459334CD303" xlink:to="loc_srt_ProductsAndServicesDomain_FA56CF86A21CE8E0099C2459334CB382" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_VASOSTRICTandorADRENALINMember" xlink:label="loc_endp_VASOSTRICTandorADRENALINMember_3F260FED36044BD27E8A2459334D43A0" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_FA56CF86A21CE8E0099C2459334CB382" xlink:to="loc_endp_VASOSTRICTandorADRENALINMember_3F260FED36044BD27E8A2459334D43A0" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_LegalEntityAxis" xlink:label="loc_dei_LegalEntityAxis_44FDA8D4139EFA12D6982459334D081F" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesTable_66443E6A321F095C88572459334790C4" xlink:to="loc_dei_LegalEntityAxis_44FDA8D4139EFA12D6982459334D081F" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityDomain" xlink:label="loc_dei_EntityDomain_E34E8E36EB7E3220C3C42459334DD2D5" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_LegalEntityAxis_44FDA8D4139EFA12D6982459334D081F" xlink:to="loc_dei_EntityDomain_E34E8E36EB7E3220C3C42459334DD2D5" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_AmericanMedicalSystemsMember" xlink:label="loc_endp_AmericanMedicalSystemsMember_16DAF6AAB8B63ADC5FD12459334D4819" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityDomain_E34E8E36EB7E3220C3C42459334DD2D5" xlink:to="loc_endp_AmericanMedicalSystemsMember_16DAF6AAB8B63ADC5FD12459334D4819" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_ParPharmaceuticalInc.Member" xlink:label="loc_endp_ParPharmaceuticalInc.Member_F582E7566A95067737A12459334E9229" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityDomain_E34E8E36EB7E3220C3C42459334DD2D5" xlink:to="loc_endp_ParPharmaceuticalInc.Member_F582E7566A95067737A12459334E9229" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_LitigationCaseAxis" xlink:label="loc_srt_LitigationCaseAxis_17A79CE96384EB8F283F2459334EDAB1" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesTable_66443E6A321F095C88572459334790C4" xlink:to="loc_srt_LitigationCaseAxis_17A79CE96384EB8F283F2459334EDAB1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_LitigationCaseTypeDomain" xlink:label="loc_srt_LitigationCaseTypeDomain_E7D9D63C79A4212D50942459334E5049" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_LitigationCaseAxis_17A79CE96384EB8F283F2459334EDAB1" xlink:to="loc_srt_LitigationCaseTypeDomain_E7D9D63C79A4212D50942459334E5049" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_VaginalMeshCasesMember" xlink:label="loc_endp_VaginalMeshCasesMember_769D1EDA55ECA81EBEC02459334EA1C9" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_LitigationCaseTypeDomain_E7D9D63C79A4212D50942459334E5049" xlink:to="loc_endp_VaginalMeshCasesMember_769D1EDA55ECA81EBEC02459334EA1C9" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_TestosteroneCasesMember" xlink:label="loc_endp_TestosteroneCasesMember_CB4A08A404512A4E03F52459334E8884" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_LitigationCaseTypeDomain_E7D9D63C79A4212D50942459334E5049" xlink:to="loc_endp_TestosteroneCasesMember_CB4A08A404512A4E03F52459334E8884" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_OpioidRelatedMattersMember" xlink:label="loc_endp_OpioidRelatedMattersMember_19D29ABC28E4A12807932459334FE24F" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_LitigationCaseTypeDomain_E7D9D63C79A4212D50942459334E5049" xlink:to="loc_endp_OpioidRelatedMattersMember_19D29ABC28E4A12807932459334FE24F" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_LidodermMember" xlink:label="loc_endp_LidodermMember_7B02ECD0FB02C0685E2E2459334F651A" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_LitigationCaseTypeDomain_E7D9D63C79A4212D50942459334E5049" xlink:to="loc_endp_LidodermMember_7B02ECD0FB02C0685E2E2459334F651A" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_AndroGel1.62Member" xlink:label="loc_endp_AndroGel1.62Member_F4151BEC1DCF241B0D202459334F72F4" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_LitigationCaseTypeDomain_E7D9D63C79A4212D50942459334E5049" xlink:to="loc_endp_AndroGel1.62Member_F4151BEC1DCF241B0D202459334F72F4" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_PublicEmployeesRetirementSystemofMississippivs.EndoInternationalPLCMember" xlink:label="loc_endp_PublicEmployeesRetirementSystemofMississippivs.EndoInternationalPLCMember_CA5FC8E745CC4F8D7E502459334F6873" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_LitigationCaseTypeDomain_E7D9D63C79A4212D50942459334E5049" xlink:to="loc_endp_PublicEmployeesRetirementSystemofMississippivs.EndoInternationalPLCMember_CA5FC8E745CC4F8D7E502459334F6873" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_Bierv.EndoInternationalplcetal.Member" xlink:label="loc_endp_Bierv.EndoInternationalplcetal.Member_AFCB52EA7761D0309A692459334F18D8" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_LitigationCaseTypeDomain_E7D9D63C79A4212D50942459334E5049" xlink:to="loc_endp_Bierv.EndoInternationalplcetal.Member_AFCB52EA7761D0309A692459334F18D8" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_VASOSTRICTRelatedMattersMember" xlink:label="loc_endp_VASOSTRICTRelatedMattersMember_ED00B59A11B26C2587BE2459334F624C" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_LitigationCaseTypeDomain_E7D9D63C79A4212D50942459334E5049" xlink:to="loc_endp_VASOSTRICTRelatedMattersMember_ED00B59A11B26C2587BE2459334F624C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_TitleOfIndividualAxis" xlink:label="loc_srt_TitleOfIndividualAxis_7C2E4837ECBB9636516924593350214A" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesTable_66443E6A321F095C88572459334790C4" xlink:to="loc_srt_TitleOfIndividualAxis_7C2E4837ECBB9636516924593350214A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_TitleOfIndividualWithRelationshipToEntityDomain" xlink:label="loc_srt_TitleOfIndividualWithRelationshipToEntityDomain_403AB4DBD4C69E5AC439245933503E64" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_TitleOfIndividualAxis_7C2E4837ECBB9636516924593350214A" xlink:to="loc_srt_TitleOfIndividualWithRelationshipToEntityDomain_403AB4DBD4C69E5AC439245933503E64" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_CurrentandFormerDirectorsandOfficersMember" xlink:label="loc_endp_CurrentandFormerDirectorsandOfficersMember_85999BD5C7A5EA1D764024593350BE7B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_TitleOfIndividualWithRelationshipToEntityDomain_403AB4DBD4C69E5AC439245933503E64" xlink:to="loc_endp_CurrentandFormerDirectorsandOfficersMember_85999BD5C7A5EA1D764024593350BE7B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SubsequentEventTypeAxis" xlink:label="loc_us-gaap_SubsequentEventTypeAxis_3A73011A367B7E0E1C022459335049EA" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesTable_66443E6A321F095C88572459334790C4" xlink:to="loc_us-gaap_SubsequentEventTypeAxis_3A73011A367B7E0E1C022459335049EA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SubsequentEventTypeDomain" xlink:label="loc_us-gaap_SubsequentEventTypeDomain_6F4F4AC7948FD5BA768524593350580F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTypeAxis_3A73011A367B7E0E1C022459335049EA" xlink:to="loc_us-gaap_SubsequentEventTypeDomain_6F4F4AC7948FD5BA768524593350580F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SubsequentEventMember" xlink:label="loc_us-gaap_SubsequentEventMember_F64FCCD630EEF4A4CA672459335150B0" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTypeDomain_6F4F4AC7948FD5BA768524593350580F" xlink:to="loc_us-gaap_SubsequentEventMember_F64FCCD630EEF4A4CA672459335150B0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LossContingenciesLineItems" xlink:label="loc_us-gaap_LossContingenciesLineItems_44EADB5635E097883EF624593351CADC" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesTable_66443E6A321F095C88572459334790C4" xlink:to="loc_us-gaap_LossContingenciesLineItems_44EADB5635E097883EF624593351CADC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LossContingencyAccrualAtCarryingValue" xlink:label="loc_us-gaap_LossContingencyAccrualAtCarryingValue_3F8CB615862D361C628D24593351D79B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_44EADB5635E097883EF624593351CADC" xlink:to="loc_us-gaap_LossContingencyAccrualAtCarryingValue_3F8CB615862D361C628D24593351D79B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LossContingencyAccrualCarryingValueCurrent" xlink:label="loc_us-gaap_LossContingencyAccrualCarryingValueCurrent_7783877F7A4E16094D6A245933514527" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_44EADB5635E097883EF624593351CADC" xlink:to="loc_us-gaap_LossContingencyAccrualCarryingValueCurrent_7783877F7A4E16094D6A245933514527" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LossContingencyClaimsSettledNumber" xlink:label="loc_us-gaap_LossContingencyClaimsSettledNumber_105A6971DAD93A51EEAD24593351B4A9" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_44EADB5635E097883EF624593351CADC" xlink:to="loc_us-gaap_LossContingencyClaimsSettledNumber_105A6971DAD93A51EEAD24593351B4A9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LossContingencyAccrualPayments" xlink:label="loc_us-gaap_LossContingencyAccrualPayments_C2EDEEB70B40205282DE245933520E8D" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_44EADB5635E097883EF624593351CADC" xlink:to="loc_us-gaap_LossContingencyAccrualPayments_C2EDEEB70B40205282DE245933520E8D" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_SettlementFunds" xlink:label="loc_endp_SettlementFunds_EDFECC1B685CAF88BFFE24593352661D" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_44EADB5635E097883EF624593351CADC" xlink:to="loc_endp_SettlementFunds_EDFECC1B685CAF88BFFE24593352661D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LossContingencyPendingClaimsNumber" xlink:label="loc_us-gaap_LossContingencyPendingClaimsNumber_1E23EDDE38DEDB6F00D2245933521F68" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_44EADB5635E097883EF624593351CADC" xlink:to="loc_us-gaap_LossContingencyPendingClaimsNumber_1E23EDDE38DEDB6F00D2245933521F68" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_LossContingencyClaimsFiledByStatesNumber" xlink:label="loc_endp_LossContingencyClaimsFiledByStatesNumber_315394D4D7959212E4DE245933522FB5" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_44EADB5635E097883EF624593351CADC" xlink:to="loc_endp_LossContingencyClaimsFiledByStatesNumber_315394D4D7959212E4DE245933522FB5" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_LossContingencyNumberOfCasesFiledByHospitalsHealthSystemsUnionsWelfareFundsOrOtherThirdParty" xlink:label="loc_endp_LossContingencyNumberOfCasesFiledByHospitalsHealthSystemsUnionsWelfareFundsOrOtherThirdParty_50EB3CFFBEA0E7B74EE5245933529957" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_44EADB5635E097883EF624593351CADC" xlink:to="loc_endp_LossContingencyNumberOfCasesFiledByHospitalsHealthSystemsUnionsWelfareFundsOrOtherThirdParty_50EB3CFFBEA0E7B74EE5245933529957" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_LossContingencyNumberOfCasesAllegingPersonalInjuryAndOrWrongfulDeath" xlink:label="loc_endp_LossContingencyNumberOfCasesAllegingPersonalInjuryAndOrWrongfulDeath_5CF943C23F4F6F9E6DB2245933528473" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_44EADB5635E097883EF624593351CADC" xlink:to="loc_endp_LossContingencyNumberOfCasesAllegingPersonalInjuryAndOrWrongfulDeath_5CF943C23F4F6F9E6DB2245933528473" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_LossContingencyNumberOfPutativeClassActions" xlink:label="loc_endp_LossContingencyNumberOfPutativeClassActions_E6377D094E5916EABFEC24593352563A" xlink:type="locator" />
    <link:presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_44EADB5635E097883EF624593351CADC" xlink:to="loc_endp_LossContingencyNumberOfPutativeClassActions_E6377D094E5916EABFEC24593352563A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LitigationSettlementAmountAwardedToOtherParty" xlink:label="loc_us-gaap_LitigationSettlementAmountAwardedToOtherParty_0B199BB783BF30B7E33024593353E2FA" xlink:type="locator" />
    <link:presentationArc order="11" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_44EADB5635E097883EF624593351CADC" xlink:to="loc_us-gaap_LitigationSettlementAmountAwardedToOtherParty_0B199BB783BF30B7E33024593353E2FA" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_NumberofCausationTheoriesRejected" xlink:label="loc_endp_NumberofCausationTheoriesRejected_FB134BF1DA78447C7E56245933530A5F" xlink:type="locator" />
    <link:presentationArc order="12" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_44EADB5635E097883EF624593351CADC" xlink:to="loc_endp_NumberofCausationTheoriesRejected_FB134BF1DA78447C7E56245933530A5F" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_NumberofCausationTheories" xlink:label="loc_endp_NumberofCausationTheories_3325D8A267B2D52717F524593353D324" xlink:type="locator" />
    <link:presentationArc order="13" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_44EADB5635E097883EF624593351CADC" xlink:to="loc_endp_NumberofCausationTheories_3325D8A267B2D52717F524593353D324" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LossContingencyAccrualProvision" xlink:label="loc_us-gaap_LossContingencyAccrualProvision_D1A9940C98BAF55DC592245933535355" xlink:type="locator" />
    <link:presentationArc order="14" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_44EADB5635E097883EF624593351CADC" xlink:to="loc_us-gaap_LossContingencyAccrualProvision_D1A9940C98BAF55DC592245933535355" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LossContingencyReceivable" xlink:label="loc_us-gaap_LossContingencyReceivable_2784301D25A8B721E6442459335325F7" xlink:type="locator" />
    <link:presentationArc order="15" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_44EADB5635E097883EF624593351CADC" xlink:to="loc_us-gaap_LossContingencyReceivable_2784301D25A8B721E6442459335325F7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LossContingencyRelatedReceivableCarryingValuePeriodIncreaseDecrease" xlink:label="loc_us-gaap_LossContingencyRelatedReceivableCarryingValuePeriodIncreaseDecrease_5DB39601A66DC9A568F224593353102C" xlink:type="locator" />
    <link:presentationArc order="16" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_44EADB5635E097883EF624593351CADC" xlink:to="loc_us-gaap_LossContingencyRelatedReceivableCarryingValuePeriodIncreaseDecrease_5DB39601A66DC9A568F224593353102C" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_LossContingencyNumberOfAdditionalDefendantsNamed" xlink:label="loc_endp_LossContingencyNumberOfAdditionalDefendantsNamed_E09A6E0CDECB99FE854D245933544DD2" xlink:type="locator" />
    <link:presentationArc order="17" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_44EADB5635E097883EF624593351CADC" xlink:to="loc_endp_LossContingencyNumberOfAdditionalDefendantsNamed_E09A6E0CDECB99FE854D245933544DD2" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_LossContingencyNumberofConsultants" xlink:label="loc_endp_LossContingencyNumberofConsultants_C5020179066EC657548C24593354E8E7" xlink:type="locator" />
    <link:presentationArc order="18" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_44EADB5635E097883EF624593351CADC" xlink:to="loc_endp_LossContingencyNumberofConsultants_C5020179066EC657548C24593354E8E7" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_LossContingencyNumberOfDefendantsFilingMotionToDismiss" xlink:label="loc_endp_LossContingencyNumberOfDefendantsFilingMotionToDismiss_0AD87F5C60C114A751D72459335414C6" xlink:type="locator" />
    <link:presentationArc order="19" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_44EADB5635E097883EF624593351CADC" xlink:to="loc_endp_LossContingencyNumberOfDefendantsFilingMotionToDismiss_0AD87F5C60C114A751D72459335414C6" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_LossContingencyNumberOfDefendantsFilingMotionToDismissLackOfPersonalInjuryJurisdiction" xlink:label="loc_endp_LossContingencyNumberOfDefendantsFilingMotionToDismissLackOfPersonalInjuryJurisdiction_ECE64FEC09CD48FADA0B245933541B6F" xlink:type="locator" />
    <link:presentationArc order="20" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_44EADB5635E097883EF624593351CADC" xlink:to="loc_endp_LossContingencyNumberOfDefendantsFilingMotionToDismissLackOfPersonalInjuryJurisdiction_ECE64FEC09CD48FADA0B245933541B6F" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_LossContingencyNumberOfDefendantsFilingMotionToDismissBreachofContractClaim" xlink:label="loc_endp_LossContingencyNumberOfDefendantsFilingMotionToDismissBreachofContractClaim_326585FE005B8030FD9E24593354ED0F" xlink:type="locator" />
    <link:presentationArc order="21" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_44EADB5635E097883EF624593351CADC" xlink:to="loc_endp_LossContingencyNumberOfDefendantsFilingMotionToDismissBreachofContractClaim_326585FE005B8030FD9E24593354ED0F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LossContingencyNumberOfDefendants" xlink:label="loc_us-gaap_LossContingencyNumberOfDefendants_71B9E81B9443050A24C024593354C6B1" xlink:type="locator" />
    <link:presentationArc order="22" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_44EADB5635E097883EF624593351CADC" xlink:to="loc_us-gaap_LossContingencyNumberOfDefendants_71B9E81B9443050A24C024593354C6B1" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_LossContingencyStayOfProceedingsNumberOfDays" xlink:label="loc_endp_LossContingencyStayOfProceedingsNumberOfDays_DB6D80DE57543F8D336124593354F2DE" xlink:type="locator" />
    <link:presentationArc order="23" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_44EADB5635E097883EF624593351CADC" xlink:to="loc_endp_LossContingencyStayOfProceedingsNumberOfDays_DB6D80DE57543F8D336124593354F2DE" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_LossContingencyExtensionofTemporaryStayNumberofDays" xlink:label="loc_endp_LossContingencyExtensionofTemporaryStayNumberofDays_897F3DB390C164A8A9EC245933554383" xlink:type="locator" />
    <link:presentationArc order="24" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_44EADB5635E097883EF624593351CADC" xlink:to="loc_endp_LossContingencyExtensionofTemporaryStayNumberofDays_897F3DB390C164A8A9EC245933554383" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_LossContingencyNumberofDaysforPlaintifftoFileNotice" xlink:label="loc_endp_LossContingencyNumberofDaysforPlaintifftoFileNotice_236C952676AF5435DA992459335553A2" xlink:type="locator" />
    <link:presentationArc order="25" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_44EADB5635E097883EF624593351CADC" xlink:to="loc_endp_LossContingencyNumberofDaysforPlaintifftoFileNotice_236C952676AF5435DA992459335553A2" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_LossContingencyLawsuitFilingPeriod" xlink:label="loc_endp_LossContingencyLawsuitFilingPeriod_19EB29826F9FA474E5E5245933559545" xlink:type="locator" />
    <link:presentationArc order="26" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_44EADB5635E097883EF624593351CADC" xlink:to="loc_endp_LossContingencyLawsuitFilingPeriod_19EB29826F9FA474E5E5245933559545" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_LossContingencyStayOfApprovalPeriodHatchWaxmanAct" xlink:label="loc_endp_LossContingencyStayOfApprovalPeriodHatchWaxmanAct_BB007C559F2532B1A2CC24593355AAF2" xlink:type="locator" />
    <link:presentationArc order="27" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_44EADB5635E097883EF624593351CADC" xlink:to="loc_endp_LossContingencyStayOfApprovalPeriodHatchWaxmanAct_BB007C559F2532B1A2CC24593355AAF2" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/CommitmentsAndContingenciesScheduleOfLossContingenciesDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_F859444B918D8F995DDEDB1E04B6279A" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LossContingenciesTable" xlink:label="loc_us-gaap_LossContingenciesTable_CCCE0FF7351A40FA0EBBDB1E04B62E92" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_F859444B918D8F995DDEDB1E04B6279A" xlink:to="loc_us-gaap_LossContingenciesTable_CCCE0FF7351A40FA0EBBDB1E04B62E92" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_LitigationCaseAxis" xlink:label="loc_srt_LitigationCaseAxis_D2181E3E2BEA30ED4142DB1E04B62F40" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesTable_CCCE0FF7351A40FA0EBBDB1E04B62E92" xlink:to="loc_srt_LitigationCaseAxis_D2181E3E2BEA30ED4142DB1E04B62F40" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_LitigationCaseTypeDomain" xlink:label="loc_srt_LitigationCaseTypeDomain_DAF32930C2E55B78F035DB1E04B6C835" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_LitigationCaseAxis_D2181E3E2BEA30ED4142DB1E04B62F40" xlink:to="loc_srt_LitigationCaseTypeDomain_DAF32930C2E55B78F035DB1E04B6C835" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_VaginalMeshCasesMember" xlink:label="loc_endp_VaginalMeshCasesMember_4FDBE3CE58075BC4C35BDB1E04B6DC72" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_LitigationCaseTypeDomain_DAF32930C2E55B78F035DB1E04B6C835" xlink:to="loc_endp_VaginalMeshCasesMember_4FDBE3CE58075BC4C35BDB1E04B6DC72" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LossContingenciesByNatureOfContingencyAxis" xlink:label="loc_us-gaap_LossContingenciesByNatureOfContingencyAxis_7A2316DFA2F564B97C45DB1E04B6283F" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesTable_CCCE0FF7351A40FA0EBBDB1E04B62E92" xlink:to="loc_us-gaap_LossContingenciesByNatureOfContingencyAxis_7A2316DFA2F564B97C45DB1E04B6283F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LossContingencyNatureDomain" xlink:label="loc_us-gaap_LossContingencyNatureDomain_F7F6290E7A63A60F8513DB1E04B6379A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesByNatureOfContingencyAxis_7A2316DFA2F564B97C45DB1E04B6283F" xlink:to="loc_us-gaap_LossContingencyNatureDomain_F7F6290E7A63A60F8513DB1E04B6379A" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_ProductLiabilityMember" xlink:label="loc_endp_ProductLiabilityMember_6446DD0E3E375A714BD8DB1E04B6C640" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingencyNatureDomain_F7F6290E7A63A60F8513DB1E04B6379A" xlink:to="loc_endp_ProductLiabilityMember_6446DD0E3E375A714BD8DB1E04B6C640" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LossContingenciesLineItems" xlink:label="loc_us-gaap_LossContingenciesLineItems_EE8BD2FCB0D5FEC7E8B7DB1E04B6FF44" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesTable_CCCE0FF7351A40FA0EBBDB1E04B62E92" xlink:to="loc_us-gaap_LossContingenciesLineItems_EE8BD2FCB0D5FEC7E8B7DB1E04B6FF44" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_SettlementFundsRollForward" xlink:label="loc_endp_SettlementFundsRollForward_2ED0B9C34BEC6DF394ADDB1E04B6E94A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_EE8BD2FCB0D5FEC7E8B7DB1E04B6FF44" xlink:to="loc_endp_SettlementFundsRollForward_2ED0B9C34BEC6DF394ADDB1E04B6E94A" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_SettlementFunds" xlink:label="loc_endp_SettlementFunds_901B20578315082647B9DB1E04B601B0" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_SettlementFundsRollForward_2ED0B9C34BEC6DF394ADDB1E04B6E94A" xlink:to="loc_endp_SettlementFunds_901B20578315082647B9DB1E04B601B0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LossContingencyAccrualProvision" xlink:label="loc_us-gaap_LossContingencyAccrualProvision_BBCF69D890710468F6FFDB1E04B60ECB" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_SettlementFundsRollForward_2ED0B9C34BEC6DF394ADDB1E04B6E94A" xlink:to="loc_us-gaap_LossContingencyAccrualProvision_BBCF69D890710468F6FFDB1E04B60ECB" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_SettlementFundsAdditions" xlink:label="loc_endp_SettlementFundsAdditions_85470A73CC7983D79D69DB1E04B6DBDC" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_SettlementFundsRollForward_2ED0B9C34BEC6DF394ADDB1E04B6E94A" xlink:to="loc_endp_SettlementFundsAdditions_85470A73CC7983D79D69DB1E04B6DBDC" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_SettlementFundsPaymentsToPlaintiffCounselFromQualifiedSettlementFunds" xlink:label="loc_endp_SettlementFundsPaymentsToPlaintiffCounselFromQualifiedSettlementFunds_1BC9A4DB5242EFE16E89DB1E04B659D2" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_SettlementFundsRollForward_2ED0B9C34BEC6DF394ADDB1E04B6E94A" xlink:to="loc_endp_SettlementFundsPaymentsToPlaintiffCounselFromQualifiedSettlementFunds_1BC9A4DB5242EFE16E89DB1E04B659D2" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_SettlementFundsOther" xlink:label="loc_endp_SettlementFundsOther_F699AE070A95EA810013DB1E04B6A6A9" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_SettlementFundsRollForward_2ED0B9C34BEC6DF394ADDB1E04B6E94A" xlink:to="loc_endp_SettlementFundsOther_F699AE070A95EA810013DB1E04B6A6A9" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_SettlementFunds" xlink:label="loc_endp_SettlementFunds_16F79F95D5134184E46DDB1E04B6E7AB" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_SettlementFundsRollForward_2ED0B9C34BEC6DF394ADDB1E04B6E94A" xlink:to="loc_endp_SettlementFunds_16F79F95D5134184E46DDB1E04B6E7AB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LossContingencyAccrualRollForward" xlink:label="loc_us-gaap_LossContingencyAccrualRollForward_C5506108718DADD5509FDB1E04B6762C" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_EE8BD2FCB0D5FEC7E8B7DB1E04B6FF44" xlink:to="loc_us-gaap_LossContingencyAccrualRollForward_C5506108718DADD5509FDB1E04B6762C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LossContingencyAccrualAtCarryingValue" xlink:label="loc_us-gaap_LossContingencyAccrualAtCarryingValue_22EA22C6EB845295537EDB1E04C63488" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingencyAccrualRollForward_C5506108718DADD5509FDB1E04B6762C" xlink:to="loc_us-gaap_LossContingencyAccrualAtCarryingValue_22EA22C6EB845295537EDB1E04C63488" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_LossContingencyAccrualPaymentsToPlaintiffCounselFromQualifiedSettlementFunds" xlink:label="loc_endp_LossContingencyAccrualPaymentsToPlaintiffCounselFromQualifiedSettlementFunds_64D09B63E6A458E9C183DB1E04C60900" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingencyAccrualRollForward_C5506108718DADD5509FDB1E04B6762C" xlink:to="loc_endp_LossContingencyAccrualPaymentsToPlaintiffCounselFromQualifiedSettlementFunds_64D09B63E6A458E9C183DB1E04C60900" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_LossContingencyAccrualPaymentsToPlaintiffCounsel" xlink:label="loc_endp_LossContingencyAccrualPaymentsToPlaintiffCounsel_94C1C3562D6CA771E859DB1E04C6C4E3" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingencyAccrualRollForward_C5506108718DADD5509FDB1E04B6762C" xlink:to="loc_endp_LossContingencyAccrualPaymentsToPlaintiffCounsel_94C1C3562D6CA771E859DB1E04C6C4E3" xlink:type="arc" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingencyAccrualRollForward_C5506108718DADD5509FDB1E04B6762C" xlink:to="loc_endp_SettlementFundsOther_F699AE070A95EA810013DB1E04B6A6A9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LossContingencyAccrualAtCarryingValue" xlink:label="loc_us-gaap_LossContingencyAccrualAtCarryingValue_E1EC3A32954F60E18412DB1E04C723E0" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingencyAccrualRollForward_C5506108718DADD5509FDB1E04B6762C" xlink:to="loc_us-gaap_LossContingencyAccrualAtCarryingValue_E1EC3A32954F60E18412DB1E04C723E0" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/CommitmentsAndContingenciesTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_F2C99A02A5AD59DE98F589456C80D7AB" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfLossContingenciesByContingencyTextBlock" xlink:label="loc_us-gaap_ScheduleOfLossContingenciesByContingencyTextBlock_8817DD6262A05758AE96EEDC7DC58E81" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_F2C99A02A5AD59DE98F589456C80D7AB" xlink:to="loc_us-gaap_ScheduleOfLossContingenciesByContingencyTextBlock_8817DD6262A05758AE96EEDC7DC58E81" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/CondensedConsolidatedBalanceSheetsUnaudited" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StatementOfFinancialPositionAbstract" xlink:label="loc_us-gaap_StatementOfFinancialPositionAbstract_1C146995811992EEC80DEFF6628BE6C5" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AssetsAbstract" xlink:label="loc_us-gaap_AssetsAbstract_05D4D5114DFBF74109A0EFF6628BF59E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_1C146995811992EEC80DEFF6628BE6C5" xlink:to="loc_us-gaap_AssetsAbstract_05D4D5114DFBF74109A0EFF6628BF59E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AssetsCurrentAbstract" xlink:label="loc_us-gaap_AssetsCurrentAbstract_103DAE66948312ECA8D1EFF6628B9EBE" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_05D4D5114DFBF74109A0EFF6628BF59E" xlink:to="loc_us-gaap_AssetsCurrentAbstract_103DAE66948312ECA8D1EFF6628B9EBE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_B52297B302CD2DFD1CE6EFF6628B45D7" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_103DAE66948312ECA8D1EFF6628B9EBE" xlink:to="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_B52297B302CD2DFD1CE6EFF6628B45D7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestrictedCashAndCashEquivalentsAtCarryingValue" xlink:label="loc_us-gaap_RestrictedCashAndCashEquivalentsAtCarryingValue_FF27E1E949FBC44DD107EFF6628B0BF3" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_103DAE66948312ECA8D1EFF6628B9EBE" xlink:to="loc_us-gaap_RestrictedCashAndCashEquivalentsAtCarryingValue_FF27E1E949FBC44DD107EFF6628B0BF3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AccountsReceivableNetCurrent" xlink:label="loc_us-gaap_AccountsReceivableNetCurrent_D88E43A9173AC72EE615EFF6628B17A2" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_103DAE66948312ECA8D1EFF6628B9EBE" xlink:to="loc_us-gaap_AccountsReceivableNetCurrent_D88E43A9173AC72EE615EFF6628B17A2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_InventoryNet" xlink:label="loc_us-gaap_InventoryNet_04BAF3A6509781FE3ED1EFF6628BBA6A" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_103DAE66948312ECA8D1EFF6628B9EBE" xlink:to="loc_us-gaap_InventoryNet_04BAF3A6509781FE3ED1EFF6628BBA6A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_PrepaidExpenseAndOtherAssetsCurrent" xlink:label="loc_us-gaap_PrepaidExpenseAndOtherAssetsCurrent_470C206A8EFE897C16ADEFF662914916" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_103DAE66948312ECA8D1EFF6628B9EBE" xlink:to="loc_us-gaap_PrepaidExpenseAndOtherAssetsCurrent_470C206A8EFE897C16ADEFF662914916" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeTaxesReceivable" xlink:label="loc_us-gaap_IncomeTaxesReceivable_606105E6AA44D0CFE2EBEFF6629124F7" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_103DAE66948312ECA8D1EFF6628B9EBE" xlink:to="loc_us-gaap_IncomeTaxesReceivable_606105E6AA44D0CFE2EBEFF6629124F7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AssetsCurrent" xlink:label="loc_us-gaap_AssetsCurrent_62FF78F5340625F60EBAEFF662918FE5" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_103DAE66948312ECA8D1EFF6628B9EBE" xlink:to="loc_us-gaap_AssetsCurrent_62FF78F5340625F60EBAEFF662918FE5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_PropertyPlantAndEquipmentNet" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_A2C6321BD128FA355CECEFF662919B71" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_05D4D5114DFBF74109A0EFF6628BF59E" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentNet_A2C6321BD128FA355CECEFF662919B71" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OperatingLeaseRightOfUseAsset" xlink:label="loc_us-gaap_OperatingLeaseRightOfUseAsset_3FEFD25289C4E0A2AD1EEFF662918EE3" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_05D4D5114DFBF74109A0EFF6628BF59E" xlink:to="loc_us-gaap_OperatingLeaseRightOfUseAsset_3FEFD25289C4E0A2AD1EEFF662918EE3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_Goodwill" xlink:label="loc_us-gaap_Goodwill_A3BD67D0EF3A15BF81A1EFF66291A1D3" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_05D4D5114DFBF74109A0EFF6628BF59E" xlink:to="loc_us-gaap_Goodwill_A3BD67D0EF3A15BF81A1EFF66291A1D3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IntangibleAssetsNetExcludingGoodwill" xlink:label="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_44EAA4D32129C96D6F59EFF662917C2B" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_05D4D5114DFBF74109A0EFF6628BF59E" xlink:to="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_44EAA4D32129C96D6F59EFF662917C2B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DeferredIncomeTaxAssetsNet" xlink:label="loc_us-gaap_DeferredIncomeTaxAssetsNet_979F38E1DE5A448257DDEFF66291F78D" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_05D4D5114DFBF74109A0EFF6628BF59E" xlink:to="loc_us-gaap_DeferredIncomeTaxAssetsNet_979F38E1DE5A448257DDEFF66291F78D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OtherAssetsNoncurrent" xlink:label="loc_us-gaap_OtherAssetsNoncurrent_4FC37A910D67B393CE0FEFF66291AD51" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_05D4D5114DFBF74109A0EFF6628BF59E" xlink:to="loc_us-gaap_OtherAssetsNoncurrent_4FC37A910D67B393CE0FEFF66291AD51" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_Assets" xlink:label="loc_us-gaap_Assets_17451D2D8643CD881675EFF662911011" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_05D4D5114DFBF74109A0EFF6628BF59E" xlink:to="loc_us-gaap_Assets_17451D2D8643CD881675EFF662911011" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LiabilitiesAndStockholdersEquityAbstract" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_6CBE8DE190E486B6136BEFF66291411C" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_1C146995811992EEC80DEFF6628BE6C5" xlink:to="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_6CBE8DE190E486B6136BEFF66291411C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LiabilitiesCurrentAbstract" xlink:label="loc_us-gaap_LiabilitiesCurrentAbstract_558917D64AAE2CBAAC70EFF662918436" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_6CBE8DE190E486B6136BEFF66291411C" xlink:to="loc_us-gaap_LiabilitiesCurrentAbstract_558917D64AAE2CBAAC70EFF662918436" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AccountsPayableAndAccruedLiabilitiesCurrent" xlink:label="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesCurrent_813723099E1206F253CAEFF6629153DE" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_558917D64AAE2CBAAC70EFF662918436" xlink:to="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesCurrent_813723099E1206F253CAEFF6629153DE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LossContingencyAccrualCarryingValueCurrent" xlink:label="loc_us-gaap_LossContingencyAccrualCarryingValueCurrent_D50E830A07359D43DEF2EFF66291B8A3" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_558917D64AAE2CBAAC70EFF662918436" xlink:to="loc_us-gaap_LossContingencyAccrualCarryingValueCurrent_D50E830A07359D43DEF2EFF66291B8A3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OperatingLeaseLiabilityCurrent" xlink:label="loc_us-gaap_OperatingLeaseLiabilityCurrent_A9E578497A80B1EDF09DEFF66291D714" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_558917D64AAE2CBAAC70EFF662918436" xlink:to="loc_us-gaap_OperatingLeaseLiabilityCurrent_A9E578497A80B1EDF09DEFF66291D714" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LongTermDebtCurrent" xlink:label="loc_us-gaap_LongTermDebtCurrent_D72BB815B9DEF097D990EFF6629185F0" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_558917D64AAE2CBAAC70EFF662918436" xlink:to="loc_us-gaap_LongTermDebtCurrent_D72BB815B9DEF097D990EFF6629185F0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AccruedIncomeTaxesCurrent" xlink:label="loc_us-gaap_AccruedIncomeTaxesCurrent_6E31FBABA4AD3F0D9971EFF662915D13" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_558917D64AAE2CBAAC70EFF662918436" xlink:to="loc_us-gaap_AccruedIncomeTaxesCurrent_6E31FBABA4AD3F0D9971EFF662915D13" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LiabilitiesCurrent" xlink:label="loc_us-gaap_LiabilitiesCurrent_C9CD4665D6A77E9B8F6AEFF662910ADB" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_558917D64AAE2CBAAC70EFF662918436" xlink:to="loc_us-gaap_LiabilitiesCurrent_C9CD4665D6A77E9B8F6AEFF662910ADB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DeferredIncomeTaxLiabilitiesNet" xlink:label="loc_us-gaap_DeferredIncomeTaxLiabilitiesNet_F79B172C5B96632D0406EFF66291D70D" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_6CBE8DE190E486B6136BEFF66291411C" xlink:to="loc_us-gaap_DeferredIncomeTaxLiabilitiesNet_F79B172C5B96632D0406EFF66291D70D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LongTermDebtNoncurrent" xlink:label="loc_us-gaap_LongTermDebtNoncurrent_D264901CAD53D1ABA6BEEFF66291DFFB" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_6CBE8DE190E486B6136BEFF66291411C" xlink:to="loc_us-gaap_LongTermDebtNoncurrent_D264901CAD53D1ABA6BEEFF66291DFFB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LossContingencyAccrualCarryingValueNoncurrent" xlink:label="loc_us-gaap_LossContingencyAccrualCarryingValueNoncurrent_CA4AAD609872D30FA463EFF66291385E" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_6CBE8DE190E486B6136BEFF66291411C" xlink:to="loc_us-gaap_LossContingencyAccrualCarryingValueNoncurrent_CA4AAD609872D30FA463EFF66291385E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OperatingLeaseLiabilityNoncurrent" xlink:label="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_13F38F49A26DE8BA6BFCEFF66291BD6E" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_6CBE8DE190E486B6136BEFF66291411C" xlink:to="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_13F38F49A26DE8BA6BFCEFF66291BD6E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OtherLiabilitiesNoncurrent" xlink:label="loc_us-gaap_OtherLiabilitiesNoncurrent_A4AF3BD5270AF2AD4DF0EFF662910762" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_6CBE8DE190E486B6136BEFF66291411C" xlink:to="loc_us-gaap_OtherLiabilitiesNoncurrent_A4AF3BD5270AF2AD4DF0EFF662910762" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CommitmentsAndContingencies" xlink:label="loc_us-gaap_CommitmentsAndContingencies_12434C51A18FF9C3152FEFF662912036" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_6CBE8DE190E486B6136BEFF66291411C" xlink:to="loc_us-gaap_CommitmentsAndContingencies_12434C51A18FF9C3152FEFF662912036" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterestAbstract" xlink:label="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterestAbstract_F6BC12F4A69693077835EFF66291CB82" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_6CBE8DE190E486B6136BEFF66291411C" xlink:to="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterestAbstract_F6BC12F4A69693077835EFF66291CB82" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_EuroDeferredStockValueIssued" xlink:label="loc_endp_EuroDeferredStockValueIssued_2C1F45AF5023EDF10405EFF6629110A8" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterestAbstract_F6BC12F4A69693077835EFF66291CB82" xlink:to="loc_endp_EuroDeferredStockValueIssued_2C1F45AF5023EDF10405EFF6629110A8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CommonStockValue" xlink:label="loc_us-gaap_CommonStockValue_24C0F065EF9544C25378EFF66291F26B" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterestAbstract_F6BC12F4A69693077835EFF66291CB82" xlink:to="loc_us-gaap_CommonStockValue_24C0F065EF9544C25378EFF66291F26B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AdditionalPaidInCapital" xlink:label="loc_us-gaap_AdditionalPaidInCapital_F091D7A6CB3EC5291721EFF662912DF5" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterestAbstract_F6BC12F4A69693077835EFF66291CB82" xlink:to="loc_us-gaap_AdditionalPaidInCapital_F091D7A6CB3EC5291721EFF662912DF5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RetainedEarningsAccumulatedDeficit" xlink:label="loc_us-gaap_RetainedEarningsAccumulatedDeficit_4E53DB3F46C68C25AC4AEFF662910907" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterestAbstract_F6BC12F4A69693077835EFF66291CB82" xlink:to="loc_us-gaap_RetainedEarningsAccumulatedDeficit_4E53DB3F46C68C25AC4AEFF662910907" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_F75FEFEB25AB7AC3FD42EFF662910855" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterestAbstract_F6BC12F4A69693077835EFF66291CB82" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_F75FEFEB25AB7AC3FD42EFF662910855" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StockholdersEquity" xlink:label="loc_us-gaap_StockholdersEquity_D2E34E71DD1D795D387CEFF66296E084" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterestAbstract_F6BC12F4A69693077835EFF66291CB82" xlink:to="loc_us-gaap_StockholdersEquity_D2E34E71DD1D795D387CEFF66296E084" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LiabilitiesAndStockholdersEquity" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquity_AA8962F930F32C82FB06EFF66296C458" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_6CBE8DE190E486B6136BEFF66291411C" xlink:to="loc_us-gaap_LiabilitiesAndStockholdersEquity_AA8962F930F32C82FB06EFF66296C458" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/CondensedConsolidatedBalanceSheetsUnauditedParenthetical" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StatementOfFinancialPositionAbstract" xlink:label="loc_us-gaap_StatementOfFinancialPositionAbstract_F63EB277682B0CEBA6212D6DBB8E8AB3" xlink:type="locator" />
    <link:loc xlink:href="endp-20190930.xsd#endp_EuroDeferredSharesParorStatedValuePerShare" xlink:label="loc_endp_EuroDeferredSharesParorStatedValuePerShare_606BD1AA6A428D8DD8932D6DBB8E5B24" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_F63EB277682B0CEBA6212D6DBB8E8AB3" xlink:to="loc_endp_EuroDeferredSharesParorStatedValuePerShare_606BD1AA6A428D8DD8932D6DBB8E5B24" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_EuroDeferredSharesSharesAuthorized" xlink:label="loc_endp_EuroDeferredSharesSharesAuthorized_629248D8DCB398759C362D6DBB8FF888" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_F63EB277682B0CEBA6212D6DBB8E8AB3" xlink:to="loc_endp_EuroDeferredSharesSharesAuthorized_629248D8DCB398759C362D6DBB8FF888" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_EuroDeferredSharesSharesIssued" xlink:label="loc_endp_EuroDeferredSharesSharesIssued_64FBEC6FF7D198054E892D6DBB8F10C6" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_F63EB277682B0CEBA6212D6DBB8E8AB3" xlink:to="loc_endp_EuroDeferredSharesSharesIssued_64FBEC6FF7D198054E892D6DBB8F10C6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CommonStockParOrStatedValuePerShare" xlink:label="loc_us-gaap_CommonStockParOrStatedValuePerShare_BDEB8E20C5042DA387F52D6DBB8F7848" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_F63EB277682B0CEBA6212D6DBB8E8AB3" xlink:to="loc_us-gaap_CommonStockParOrStatedValuePerShare_BDEB8E20C5042DA387F52D6DBB8F7848" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CommonStockSharesAuthorized" xlink:label="loc_us-gaap_CommonStockSharesAuthorized_C0BB242B4C4558C6984E2D6DBB8FD9EE" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_F63EB277682B0CEBA6212D6DBB8E8AB3" xlink:to="loc_us-gaap_CommonStockSharesAuthorized_C0BB242B4C4558C6984E2D6DBB8FD9EE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CommonStockSharesIssued" xlink:label="loc_us-gaap_CommonStockSharesIssued_331AAB7529E6204C20042D6DBB8FCD02" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_F63EB277682B0CEBA6212D6DBB8E8AB3" xlink:to="loc_us-gaap_CommonStockSharesIssued_331AAB7529E6204C20042D6DBB8FCD02" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CommonStockSharesOutstanding" xlink:label="loc_us-gaap_CommonStockSharesOutstanding_74638305B6A5710087B42D6DBB901DEF" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_F63EB277682B0CEBA6212D6DBB8E8AB3" xlink:to="loc_us-gaap_CommonStockSharesOutstanding_74638305B6A5710087B42D6DBB901DEF" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/CondensedConsolidatedStatementsOfCashFlowsUnaudited" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StatementOfCashFlowsAbstract" xlink:label="loc_us-gaap_StatementOfCashFlowsAbstract_313E8E72A65746C9EC0A50DDE1875BD0" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_FBDF5958BFDE2682457C50DDE1887579" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_313E8E72A65746C9EC0A50DDE1875BD0" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_FBDF5958BFDE2682457C50DDE1887579" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_NetIncomeLoss" xlink:label="loc_us-gaap_NetIncomeLoss_B9896AD63B08D51D4BBC50DDE18880FC" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_FBDF5958BFDE2682457C50DDE1887579" xlink:to="loc_us-gaap_NetIncomeLoss_B9896AD63B08D51D4BBC50DDE18880FC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract" xlink:label="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_0723ADF3265D61F1342950DDE1890403" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_FBDF5958BFDE2682457C50DDE1887579" xlink:to="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_0723ADF3265D61F1342950DDE1890403" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DepreciationAndAmortization" xlink:label="loc_us-gaap_DepreciationAndAmortization_031811962ECA6C297E3350DDE18963F8" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_0723ADF3265D61F1342950DDE1890403" xlink:to="loc_us-gaap_DepreciationAndAmortization_031811962ECA6C297E3350DDE18963F8" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_InventoryStepUp" xlink:label="loc_endp_InventoryStepUp_A9C1787C88BEE54D649750DDE1891D25" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_0723ADF3265D61F1342950DDE1890403" xlink:to="loc_endp_InventoryStepUp_A9C1787C88BEE54D649750DDE1891D25" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensation" xlink:label="loc_us-gaap_ShareBasedCompensation_02133D1DD5E9E5E0975150DDE18A4CD7" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_0723ADF3265D61F1342950DDE1890403" xlink:to="loc_us-gaap_ShareBasedCompensation_02133D1DD5E9E5E0975150DDE18A4CD7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AmortizationOfFinancingCostsAndDiscounts" xlink:label="loc_us-gaap_AmortizationOfFinancingCostsAndDiscounts_CD16EDED93E241543C7B50DDE18AD366" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_0723ADF3265D61F1342950DDE1890403" xlink:to="loc_us-gaap_AmortizationOfFinancingCostsAndDiscounts_CD16EDED93E241543C7B50DDE18AD366" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DeferredIncomeTaxesAndTaxCredits" xlink:label="loc_us-gaap_DeferredIncomeTaxesAndTaxCredits_C98F5C15C80E746FCE3050DDE18BFC07" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_0723ADF3265D61F1342950DDE1890403" xlink:to="loc_us-gaap_DeferredIncomeTaxesAndTaxCredits_C98F5C15C80E746FCE3050DDE18BFC07" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1_B220F0252DDD378E98A350DDE18BB425" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_0723ADF3265D61F1342950DDE1890403" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1_B220F0252DDD378E98A350DDE18BB425" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_GainsLossesOnExtinguishmentOfDebt" xlink:label="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_47FC425E1BF485A079F850DDE18B54B1" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_0723ADF3265D61F1342950DDE1890403" xlink:to="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_47FC425E1BF485A079F850DDE18B54B1" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_AssetImpairmentChargesIncludingContinuingandDiscontinuedOperations" xlink:label="loc_endp_AssetImpairmentChargesIncludingContinuingandDiscontinuedOperations_7BE664C3D3D07BF9B04950DDE18C51F6" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_0723ADF3265D61F1342950DDE1890403" xlink:to="loc_endp_AssetImpairmentChargesIncludingContinuingandDiscontinuedOperations_7BE664C3D3D07BF9B04950DDE18C51F6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_GainLossOnSaleOfBusiness" xlink:label="loc_us-gaap_GainLossOnSaleOfBusiness_6380EEF969F19D98B19650DDE18C6DC5" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_0723ADF3265D61F1342950DDE1890403" xlink:to="loc_us-gaap_GainLossOnSaleOfBusiness_6380EEF969F19D98B19650DDE18C6DC5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncreaseDecreaseInOperatingCapitalAbstract" xlink:label="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_FA3EFA5C93CDB7005FBE50DDE18C5DCD" xlink:type="locator" />
    <link:presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_0723ADF3265D61F1342950DDE1890403" xlink:to="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_FA3EFA5C93CDB7005FBE50DDE18C5DCD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncreaseDecreaseInAccountsReceivable" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsReceivable_426B2589E6511D5BFCCB50DDE18C1003" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_FA3EFA5C93CDB7005FBE50DDE18C5DCD" xlink:to="loc_us-gaap_IncreaseDecreaseInAccountsReceivable_426B2589E6511D5BFCCB50DDE18C1003" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncreaseDecreaseInInventories" xlink:label="loc_us-gaap_IncreaseDecreaseInInventories_C7ECF894FA6C8B86077E50DDE18DBFA9" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_FA3EFA5C93CDB7005FBE50DDE18C5DCD" xlink:to="loc_us-gaap_IncreaseDecreaseInInventories_C7ECF894FA6C8B86077E50DDE18DBFA9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets" xlink:label="loc_us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets_6EF6BE7E87B054E20DBD50DDE18E6D74" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_FA3EFA5C93CDB7005FBE50DDE18C5DCD" xlink:to="loc_us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets_6EF6BE7E87B054E20DBD50DDE18E6D74" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities_EB0385B32D6E39A036B950DDE18EB3DF" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_FA3EFA5C93CDB7005FBE50DDE18C5DCD" xlink:to="loc_us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities_EB0385B32D6E39A036B950DDE18EB3DF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncreaseDecreaseInIncomeTaxesPayableNetOfIncomeTaxesReceivable" xlink:label="loc_us-gaap_IncreaseDecreaseInIncomeTaxesPayableNetOfIncomeTaxesReceivable_A725708B06FEA5975B1350DDE18E15A0" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_FA3EFA5C93CDB7005FBE50DDE18C5DCD" xlink:to="loc_us-gaap_IncreaseDecreaseInIncomeTaxesPayableNetOfIncomeTaxesReceivable_A725708B06FEA5975B1350DDE18E15A0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_3779A0B19E9F8593D2C850DDE18F4B95" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_FBDF5958BFDE2682457C50DDE1887579" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_3779A0B19E9F8593D2C850DDE18F4B95" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_4C439133CD3F6FF782BE50DDE18F6793" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_313E8E72A65746C9EC0A50DDE1875BD0" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_4C439133CD3F6FF782BE50DDE18F6793" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_PaymentsToAcquirePropertyPlantAndEquipment" xlink:label="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_D43739108D68A3E921E650DDE18F5CFC" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_4C439133CD3F6FF782BE50DDE18F6793" xlink:to="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_D43739108D68A3E921E650DDE18F5CFC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_InterestPaidCapitalized" xlink:label="loc_us-gaap_InterestPaidCapitalized_686684664383BE2CBFBD50DDE190C4A2" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_4C439133CD3F6FF782BE50DDE18F6793" xlink:to="loc_us-gaap_InterestPaidCapitalized_686684664383BE2CBFBD50DDE190C4A2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ProceedsFromDivestitureOfBusinesses" xlink:label="loc_us-gaap_ProceedsFromDivestitureOfBusinesses_BB11EF0CD71319D1B1C250DDE1909D2A" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_4C439133CD3F6FF782BE50DDE18F6793" xlink:to="loc_us-gaap_ProceedsFromDivestitureOfBusinesses_BB11EF0CD71319D1B1C250DDE1909D2A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_PaymentsForProceedsFromOtherInvestingActivities" xlink:label="loc_us-gaap_PaymentsForProceedsFromOtherInvestingActivities_C646176C4CB21E4F622F50DDE191F5C8" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_4C439133CD3F6FF782BE50DDE18F6793" xlink:to="loc_us-gaap_PaymentsForProceedsFromOtherInvestingActivities_C646176C4CB21E4F622F50DDE191F5C8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_49F1C4C15DC47D6DA6B450DDE1917983" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_4C439133CD3F6FF782BE50DDE18F6793" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_49F1C4C15DC47D6DA6B450DDE1917983" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_765CBFEF07090E7DCC6650DDE1915E3C" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_313E8E72A65746C9EC0A50DDE1875BD0" xlink:to="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_765CBFEF07090E7DCC6650DDE1915E3C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ProceedsFromNotesPayable" xlink:label="loc_us-gaap_ProceedsFromNotesPayable_300A2985A5703C543D3950DDE19151F1" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_765CBFEF07090E7DCC6650DDE1915E3C" xlink:to="loc_us-gaap_ProceedsFromNotesPayable_300A2985A5703C543D3950DDE19151F1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RepaymentsOfNotesPayable" xlink:label="loc_us-gaap_RepaymentsOfNotesPayable_B197D560D65F6A337B7350DDE191E4C5" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_765CBFEF07090E7DCC6650DDE1915E3C" xlink:to="loc_us-gaap_RepaymentsOfNotesPayable_B197D560D65F6A337B7350DDE191E4C5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RepaymentsOfOtherLongTermDebt" xlink:label="loc_us-gaap_RepaymentsOfOtherLongTermDebt_1A29205724DBA4212A1050DDE192D47B" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_765CBFEF07090E7DCC6650DDE1915E3C" xlink:to="loc_us-gaap_RepaymentsOfOtherLongTermDebt_1A29205724DBA4212A1050DDE192D47B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ProceedsFromLinesOfCredit" xlink:label="loc_us-gaap_ProceedsFromLinesOfCredit_AC6947D4B8B01A2382AB50DDE1925E2E" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_765CBFEF07090E7DCC6650DDE1915E3C" xlink:to="loc_us-gaap_ProceedsFromLinesOfCredit_AC6947D4B8B01A2382AB50DDE1925E2E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RepaymentsOfDebt" xlink:label="loc_us-gaap_RepaymentsOfDebt_2F089A1513757A6FE72950DDE1922D68" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_765CBFEF07090E7DCC6650DDE1915E3C" xlink:to="loc_us-gaap_RepaymentsOfDebt_2F089A1513757A6FE72950DDE1922D68" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_PaymentForDebtExtinguishmentOrDebtPrepaymentCostAndDebtIssuanceCosts" xlink:label="loc_endp_PaymentForDebtExtinguishmentOrDebtPrepaymentCostAndDebtIssuanceCosts_CD6CCC332156592232D050DDE19351AD" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_765CBFEF07090E7DCC6650DDE1915E3C" xlink:to="loc_endp_PaymentForDebtExtinguishmentOrDebtPrepaymentCostAndDebtIssuanceCosts_CD6CCC332156592232D050DDE19351AD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_PaymentForContingentConsiderationLiabilityFinancingActivities" xlink:label="loc_us-gaap_PaymentForContingentConsiderationLiabilityFinancingActivities_55512BBF9C52A96D26C550DDE193F243" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_765CBFEF07090E7DCC6650DDE1915E3C" xlink:to="loc_us-gaap_PaymentForContingentConsiderationLiabilityFinancingActivities_55512BBF9C52A96D26C550DDE193F243" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_PaymentsRelatedToTaxWithholdingForShareBasedCompensation" xlink:label="loc_us-gaap_PaymentsRelatedToTaxWithholdingForShareBasedCompensation_EA194651452E4314E1C850DDE19369DE" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_765CBFEF07090E7DCC6650DDE1915E3C" xlink:to="loc_us-gaap_PaymentsRelatedToTaxWithholdingForShareBasedCompensation_EA194651452E4314E1C850DDE19369DE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ProceedsFromStockOptionsExercised" xlink:label="loc_us-gaap_ProceedsFromStockOptionsExercised_003170781F9F7A54812550DDE1939D0C" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_765CBFEF07090E7DCC6650DDE1915E3C" xlink:to="loc_us-gaap_ProceedsFromStockOptionsExercised_003170781F9F7A54812550DDE1939D0C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_DEA61149F834B6E26DF350DDE1942064" xlink:type="locator" />
    <link:presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_765CBFEF07090E7DCC6650DDE1915E3C" xlink:to="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_DEA61149F834B6E26DF350DDE1942064" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EffectOfExchangeRateOnCashAndCashEquivalents" xlink:label="loc_us-gaap_EffectOfExchangeRateOnCashAndCashEquivalents_29B4ED55D36A02CAB86A50DDE1940174" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_313E8E72A65746C9EC0A50DDE1875BD0" xlink:to="loc_us-gaap_EffectOfExchangeRateOnCashAndCashEquivalents_29B4ED55D36A02CAB86A50DDE1940174" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_AC3CE593F5869F88C8F150DDE194FD64" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_313E8E72A65746C9EC0A50DDE1875BD0" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_AC3CE593F5869F88C8F150DDE194FD64" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_1775C0BEE97C10D2B64550DDE194321C" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_313E8E72A65746C9EC0A50DDE1875BD0" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_1775C0BEE97C10D2B64550DDE194321C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_3F120BA6E4119EC4B27850DDE194F9CC" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_313E8E72A65746C9EC0A50DDE1875BD0" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_3F120BA6E4119EC4B27850DDE194F9CC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SupplementalCashFlowInformationAbstract" xlink:label="loc_us-gaap_SupplementalCashFlowInformationAbstract_92F9A370E42B20665D9150DDE195366F" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_313E8E72A65746C9EC0A50DDE1875BD0" xlink:to="loc_us-gaap_SupplementalCashFlowInformationAbstract_92F9A370E42B20665D9150DDE195366F" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_SettlementFundsAdditions" xlink:label="loc_endp_SettlementFundsAdditions_DCDEF19C1F4189AA2B4A50DDE1951E3A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SupplementalCashFlowInformationAbstract_92F9A370E42B20665D9150DDE195366F" xlink:to="loc_endp_SettlementFundsAdditions_DCDEF19C1F4189AA2B4A50DDE1951E3A" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_SettlementFundsPayments" xlink:label="loc_endp_SettlementFundsPayments_DB198411543F6B0B528050DDE1954621" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SupplementalCashFlowInformationAbstract_92F9A370E42B20665D9150DDE195366F" xlink:to="loc_endp_SettlementFundsPayments_DB198411543F6B0B528050DDE1954621" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_OtherPaymentsForLegalSettlements" xlink:label="loc_endp_OtherPaymentsForLegalSettlements_D15BDFBCDDCFAA05AC7A50DDE196C4FE" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SupplementalCashFlowInformationAbstract_92F9A370E42B20665D9150DDE195366F" xlink:to="loc_endp_OtherPaymentsForLegalSettlements_D15BDFBCDDCFAA05AC7A50DDE196C4FE" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/CondensedConsolidatedStatementsOfComprehensiveLossUnaudited" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract" xlink:label="loc_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract_19F5A08C38ECBE556800D076D08762EA" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_NetIncomeLoss" xlink:label="loc_us-gaap_NetIncomeLoss_8CDF85C8EE0FF389F3A4D076D087EC90" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract_19F5A08C38ECBE556800D076D08762EA" xlink:to="loc_us-gaap_NetIncomeLoss_8CDF85C8EE0FF389F3A4D076D087EC90" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTaxPeriodIncreaseDecreaseAbstract" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPeriodIncreaseDecreaseAbstract_34A86D522953360DF71BD076D08813D8" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract_19F5A08C38ECBE556800D076D08762EA" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPeriodIncreaseDecreaseAbstract_34A86D522953360DF71BD076D08813D8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPeriodIncreaseDecreaseAbstract" xlink:label="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPeriodIncreaseDecreaseAbstract_EC1D94AF2AE5AE631F6FD076D0887AF2" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPeriodIncreaseDecreaseAbstract_34A86D522953360DF71BD076D08813D8" xlink:to="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPeriodIncreaseDecreaseAbstract_EC1D94AF2AE5AE631F6FD076D0887AF2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationGainLossArisingDuringPeriodNetOfTax" xlink:label="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationGainLossArisingDuringPeriodNetOfTax_2B5B22ED0C15957E8EA1D076D088522C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPeriodIncreaseDecreaseAbstract_EC1D94AF2AE5AE631F6FD076D0887AF2" xlink:to="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationGainLossArisingDuringPeriodNetOfTax_2B5B22ED0C15957E8EA1D076D088522C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationReclassificationAdjustmentFromAOCIRealizedUponSaleOrLiquidationNetOfTax" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationReclassificationAdjustmentFromAOCIRealizedUponSaleOrLiquidationNetOfTax_B180895E53048D02FF1AD076D089733D" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPeriodIncreaseDecreaseAbstract_EC1D94AF2AE5AE631F6FD076D0887AF2" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationReclassificationAdjustmentFromAOCIRealizedUponSaleOrLiquidationNetOfTax_B180895E53048D02FF1AD076D089733D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent" xlink:label="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent_A5483030DE9326041154D076D0899029" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPeriodIncreaseDecreaseAbstract_EC1D94AF2AE5AE631F6FD076D0887AF2" xlink:to="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent_A5483030DE9326041154D076D0899029" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_03E9D3B30B188D6DD11BD076D089D3E0" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPeriodIncreaseDecreaseAbstract_34A86D522953360DF71BD076D08813D8" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_03E9D3B30B188D6DD11BD076D089D3E0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ComprehensiveIncomeNetOfTax" xlink:label="loc_us-gaap_ComprehensiveIncomeNetOfTax_D74E4C12C66941A9B9F8D076D089F14C" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPeriodIncreaseDecreaseAbstract_34A86D522953360DF71BD076D08813D8" xlink:to="loc_us-gaap_ComprehensiveIncomeNetOfTax_D74E4C12C66941A9B9F8D076D089F14C" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/CondensedConsolidatedStatementsOfOperationsUnaudited" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeStatementAbstract" xlink:label="loc_us-gaap_IncomeStatementAbstract_8E3C75DEB953A0A5AAE8EFF66278A35B" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_Revenues" xlink:label="loc_us-gaap_Revenues_D41318944BF91CF4D05EEFF662788C53" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_8E3C75DEB953A0A5AAE8EFF66278A35B" xlink:to="loc_us-gaap_Revenues_D41318944BF91CF4D05EEFF662788C53" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CostsAndExpensesAbstract" xlink:label="loc_us-gaap_CostsAndExpensesAbstract_C01B57340E1AD88DDFEFEFF662786BA7" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_8E3C75DEB953A0A5AAE8EFF66278A35B" xlink:to="loc_us-gaap_CostsAndExpensesAbstract_C01B57340E1AD88DDFEFEFF662786BA7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CostOfRevenue" xlink:label="loc_us-gaap_CostOfRevenue_0D64CFA3057C2A68F124EFF662781D11" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_C01B57340E1AD88DDFEFEFF662786BA7" xlink:to="loc_us-gaap_CostOfRevenue_0D64CFA3057C2A68F124EFF662781D11" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SellingGeneralAndAdministrativeExpense" xlink:label="loc_us-gaap_SellingGeneralAndAdministrativeExpense_41957E63C69AE35FA81CEFF66278C173" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_C01B57340E1AD88DDFEFEFF662786BA7" xlink:to="loc_us-gaap_SellingGeneralAndAdministrativeExpense_41957E63C69AE35FA81CEFF66278C173" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ResearchAndDevelopmentExpense" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpense_9D608018ED422699733AEFF6627859B7" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_C01B57340E1AD88DDFEFEFF662786BA7" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpense_9D608018ED422699733AEFF6627859B7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_GainLossRelatedToLitigationSettlement" xlink:label="loc_us-gaap_GainLossRelatedToLitigationSettlement_7E39F9DA2ED951D7231FEFF66278AEA7" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_C01B57340E1AD88DDFEFEFF662786BA7" xlink:to="loc_us-gaap_GainLossRelatedToLitigationSettlement_7E39F9DA2ED951D7231FEFF66278AEA7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AssetImpairmentCharges" xlink:label="loc_us-gaap_AssetImpairmentCharges_4C1CB380398FBEF247E4EFF66278423C" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_C01B57340E1AD88DDFEFEFF662786BA7" xlink:to="loc_us-gaap_AssetImpairmentCharges_4C1CB380398FBEF247E4EFF66278423C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessCombinationAcquisitionRelatedCosts" xlink:label="loc_us-gaap_BusinessCombinationAcquisitionRelatedCosts_9BE2E749AFDFEFC59005EFF6627843C3" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_C01B57340E1AD88DDFEFEFF662786BA7" xlink:to="loc_us-gaap_BusinessCombinationAcquisitionRelatedCosts_9BE2E749AFDFEFC59005EFF6627843C3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_InterestIncomeExpenseNet" xlink:label="loc_us-gaap_InterestIncomeExpenseNet_7E4C3368A81227902541EFF662782C54" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_8E3C75DEB953A0A5AAE8EFF66278A35B" xlink:to="loc_us-gaap_InterestIncomeExpenseNet_7E4C3368A81227902541EFF662782C54" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_GainsLossesOnExtinguishmentOfDebt" xlink:label="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_B798DBC01533CC0B9D3DEFF662786E78" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_8E3C75DEB953A0A5AAE8EFF66278A35B" xlink:to="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_B798DBC01533CC0B9D3DEFF662786E78" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_NonoperatingIncomeExpense" xlink:label="loc_us-gaap_NonoperatingIncomeExpense_BABBD772603D09EE6B6FEFF662782C82" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_8E3C75DEB953A0A5AAE8EFF66278A35B" xlink:to="loc_us-gaap_NonoperatingIncomeExpense_BABBD772603D09EE6B6FEFF662782C82" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_5E1E959C6C26C96FDB89EFF662789131" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_8E3C75DEB953A0A5AAE8EFF66278A35B" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_5E1E959C6C26C96FDB89EFF662789131" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeTaxExpenseBenefit" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_2EA7FEF07808742A3CC8EFF66278754F" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_8E3C75DEB953A0A5AAE8EFF66278A35B" xlink:to="loc_us-gaap_IncomeTaxExpenseBenefit_2EA7FEF07808742A3CC8EFF66278754F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeLossFromContinuingOperations" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperations_0C80A9544E68E3DA5CD3EFF6627818F8" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_8E3C75DEB953A0A5AAE8EFF66278A35B" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperations_0C80A9544E68E3DA5CD3EFF6627818F8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxAttributableToReportingEntity" xlink:label="loc_us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxAttributableToReportingEntity_41E019596534BEA80B64EFF662788A73" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_8E3C75DEB953A0A5AAE8EFF66278A35B" xlink:to="loc_us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxAttributableToReportingEntity_41E019596534BEA80B64EFF662788A73" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_NetIncomeLoss" xlink:label="loc_us-gaap_NetIncomeLoss_0BC496F117BC3CAB734CEFF66278D74F" xlink:type="locator" />
    <link:presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_8E3C75DEB953A0A5AAE8EFF66278A35B" xlink:to="loc_us-gaap_NetIncomeLoss_0BC496F117BC3CAB734CEFF66278D74F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EarningsPerShareBasicAbstract" xlink:label="loc_us-gaap_EarningsPerShareBasicAbstract_D7D7E55A7F32B5751F86EFF66278D03B" xlink:type="locator" />
    <link:presentationArc order="11" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_8E3C75DEB953A0A5AAE8EFF66278A35B" xlink:to="loc_us-gaap_EarningsPerShareBasicAbstract_D7D7E55A7F32B5751F86EFF66278D03B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsPerBasicShare" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsPerBasicShare_E23DE60CE79F476F80FCEFF66278F1E0" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareBasicAbstract_D7D7E55A7F32B5751F86EFF66278D03B" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsPerBasicShare_E23DE60CE79F476F80FCEFF66278F1E0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DiscontinuedOperationIncomeLossFromDiscontinuedOperationNetOfTaxPerBasicShare" xlink:label="loc_us-gaap_DiscontinuedOperationIncomeLossFromDiscontinuedOperationNetOfTaxPerBasicShare_F09130F7D7A6D5E1859CEFF66278B739" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareBasicAbstract_D7D7E55A7F32B5751F86EFF66278D03B" xlink:to="loc_us-gaap_DiscontinuedOperationIncomeLossFromDiscontinuedOperationNetOfTaxPerBasicShare_F09130F7D7A6D5E1859CEFF66278B739" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EarningsPerShareBasic" xlink:label="loc_us-gaap_EarningsPerShareBasic_C4F8FBE6FDE5ADFB201CEFF662781A5C" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareBasicAbstract_D7D7E55A7F32B5751F86EFF66278D03B" xlink:to="loc_us-gaap_EarningsPerShareBasic_C4F8FBE6FDE5ADFB201CEFF662781A5C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EarningsPerShareDilutedAbstract" xlink:label="loc_us-gaap_EarningsPerShareDilutedAbstract_97E9FCE46F66F700894CEFF6627866BF" xlink:type="locator" />
    <link:presentationArc order="12" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_8E3C75DEB953A0A5AAE8EFF66278A35B" xlink:to="loc_us-gaap_EarningsPerShareDilutedAbstract_97E9FCE46F66F700894CEFF6627866BF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsPerDilutedShare" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsPerDilutedShare_A45A3D27D4CB284D75F1EFF6627804F5" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareDilutedAbstract_97E9FCE46F66F700894CEFF6627866BF" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsPerDilutedShare_A45A3D27D4CB284D75F1EFF6627804F5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DiscontinuedOperationIncomeLossFromDiscontinuedOperationNetOfTaxPerDilutedShare" xlink:label="loc_us-gaap_DiscontinuedOperationIncomeLossFromDiscontinuedOperationNetOfTaxPerDilutedShare_A22BF84567E8E096F156EFF6627E6A71" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareDilutedAbstract_97E9FCE46F66F700894CEFF6627866BF" xlink:to="loc_us-gaap_DiscontinuedOperationIncomeLossFromDiscontinuedOperationNetOfTaxPerDilutedShare_A22BF84567E8E096F156EFF6627E6A71" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EarningsPerShareDiluted" xlink:label="loc_us-gaap_EarningsPerShareDiluted_76E60D2564B8FAAF3188EFF6627E57BC" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareDilutedAbstract_97E9FCE46F66F700894CEFF6627866BF" xlink:to="loc_us-gaap_EarningsPerShareDiluted_76E60D2564B8FAAF3188EFF6627E57BC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_F0D196DAAEA834843139EFF6627E7170" xlink:type="locator" />
    <link:presentationArc order="13" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_8E3C75DEB953A0A5AAE8EFF66278A35B" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_F0D196DAAEA834843139EFF6627E7170" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingBasic" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_822BAD2CD9B9647D164BEFF6627E07C3" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_F0D196DAAEA834843139EFF6627E7170" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_822BAD2CD9B9647D164BEFF6627E07C3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding" xlink:label="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_1E988F4794CA1AC9281EEFF6627E5C18" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_F0D196DAAEA834843139EFF6627E7170" xlink:to="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_1E988F4794CA1AC9281EEFF6627E5C18" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/ContractAssetsAndLiabilities" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ContractWithCustomerAssetAndLiabilityAbstract" xlink:label="loc_us-gaap_ContractWithCustomerAssetAndLiabilityAbstract_05F314A28F8C5F2486CB65B89165F8AD" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RevenueFromContractWithCustomerTextBlock" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerTextBlock_67911212F6885682A8BDC4451BC7B473" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ContractWithCustomerAssetAndLiabilityAbstract_05F314A28F8C5F2486CB65B89165F8AD" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerTextBlock_67911212F6885682A8BDC4451BC7B473" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/ContractAssetsAndLiabilitiesContractAssetsAndContractLiabilitiesFromContractsWithCustomersDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ContractWithCustomerAssetAndLiabilityAbstract" xlink:label="loc_us-gaap_ContractWithCustomerAssetAndLiabilityAbstract_45589FAFB73E3A123C82D076CCCAC816" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ContractWithCustomerAssetNet" xlink:label="loc_us-gaap_ContractWithCustomerAssetNet_B9ABBE5286C7DB353F88D076CCCACBEA" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ContractWithCustomerAssetAndLiabilityAbstract_45589FAFB73E3A123C82D076CCCAC816" xlink:to="loc_us-gaap_ContractWithCustomerAssetNet_B9ABBE5286C7DB353F88D076CCCACBEA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncreaseDecreaseInContractWithCustomerAsset" xlink:label="loc_us-gaap_IncreaseDecreaseInContractWithCustomerAsset_91BF1CDF01823FAB295DD076CCCA3A88" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ContractWithCustomerAssetAndLiabilityAbstract_45589FAFB73E3A123C82D076CCCAC816" xlink:to="loc_us-gaap_IncreaseDecreaseInContractWithCustomerAsset_91BF1CDF01823FAB295DD076CCCA3A88" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_ContractwithCustomerAssetIncreaseDecreasePercentage" xlink:label="loc_endp_ContractwithCustomerAssetIncreaseDecreasePercentage_CB01F02F4F6D6BA4A22AD076CCCA280B" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ContractWithCustomerAssetAndLiabilityAbstract_45589FAFB73E3A123C82D076CCCAC816" xlink:to="loc_endp_ContractwithCustomerAssetIncreaseDecreasePercentage_CB01F02F4F6D6BA4A22AD076CCCA280B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ContractWithCustomerLiability" xlink:label="loc_us-gaap_ContractWithCustomerLiability_40254DFA69A42DF63FF9D076CCCB323E" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ContractWithCustomerAssetAndLiabilityAbstract_45589FAFB73E3A123C82D076CCCAC816" xlink:to="loc_us-gaap_ContractWithCustomerLiability_40254DFA69A42DF63FF9D076CCCB323E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncreaseDecreaseInContractWithCustomerLiability" xlink:label="loc_us-gaap_IncreaseDecreaseInContractWithCustomerLiability_DB198ABDC6671C7EC0FFD076CCCB683C" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ContractWithCustomerAssetAndLiabilityAbstract_45589FAFB73E3A123C82D076CCCAC816" xlink:to="loc_us-gaap_IncreaseDecreaseInContractWithCustomerLiability_DB198ABDC6671C7EC0FFD076CCCB683C" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_ContractwithCustomerLiabilityIncreaseDecreasePercentage" xlink:label="loc_endp_ContractwithCustomerLiabilityIncreaseDecreasePercentage_DC3611D7C882E05C9B6FD076CCCBF492" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ContractWithCustomerAssetAndLiabilityAbstract_45589FAFB73E3A123C82D076CCCAC816" xlink:to="loc_endp_ContractwithCustomerLiabilityIncreaseDecreasePercentage_DC3611D7C882E05C9B6FD076CCCBF492" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ContractWithCustomerAssetNetCurrent" xlink:label="loc_us-gaap_ContractWithCustomerAssetNetCurrent_4966FC6AA1039FBEF37FD076CCCB721D" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ContractWithCustomerAssetAndLiabilityAbstract_45589FAFB73E3A123C82D076CCCAC816" xlink:to="loc_us-gaap_ContractWithCustomerAssetNetCurrent_4966FC6AA1039FBEF37FD076CCCB721D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ContractWithCustomerLiabilityCurrent" xlink:label="loc_us-gaap_ContractWithCustomerLiabilityCurrent_18951D569CD1EE838703D076CCCBF08A" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ContractWithCustomerAssetAndLiabilityAbstract_45589FAFB73E3A123C82D076CCCAC816" xlink:to="loc_us-gaap_ContractWithCustomerLiabilityCurrent_18951D569CD1EE838703D076CCCBF08A" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_ContractwithCustomerLiabilityIncreaseDecrease" xlink:label="loc_endp_ContractwithCustomerLiabilityIncreaseDecrease_A717E43122E259F5E9DCD076CCCB93EF" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ContractWithCustomerAssetAndLiabilityAbstract_45589FAFB73E3A123C82D076CCCAC816" xlink:to="loc_endp_ContractwithCustomerLiabilityIncreaseDecrease_A717E43122E259F5E9DCD076CCCB93EF" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_ContractwithCustomerLiabilityReductions" xlink:label="loc_endp_ContractwithCustomerLiabilityReductions_139A3A596585BC19ACB9D0892C16C1BE" xlink:type="locator" />
    <link:presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ContractWithCustomerAssetAndLiabilityAbstract_45589FAFB73E3A123C82D076CCCAC816" xlink:to="loc_endp_ContractwithCustomerLiabilityReductions_139A3A596585BC19ACB9D0892C16C1BE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ContractWithCustomerLiabilityRevenueRecognized" xlink:label="loc_us-gaap_ContractWithCustomerLiabilityRevenueRecognized_5E7195B94FEB597DBE2DD076CCCC981F" xlink:type="locator" />
    <link:presentationArc order="11" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ContractWithCustomerAssetAndLiabilityAbstract_45589FAFB73E3A123C82D076CCCAC816" xlink:to="loc_us-gaap_ContractWithCustomerLiabilityRevenueRecognized_5E7195B94FEB597DBE2DD076CCCC981F" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/ContractAssetsAndLiabilitiesNarrativeDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ContractWithCustomerAssetAndLiabilityAbstract" xlink:label="loc_us-gaap_ContractWithCustomerAssetAndLiabilityAbstract_37914BB6FC3F5734A79E75988DF41F90" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ContractWithCustomerPerformanceObligationSatisfiedInPreviousPeriod" xlink:label="loc_us-gaap_ContractWithCustomerPerformanceObligationSatisfiedInPreviousPeriod_2C5FD72338D555CFA942E1C4F43695DE" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ContractWithCustomerAssetAndLiabilityAbstract_37914BB6FC3F5734A79E75988DF41F90" xlink:to="loc_us-gaap_ContractWithCustomerPerformanceObligationSatisfiedInPreviousPeriod_2C5FD72338D555CFA942E1C4F43695DE" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/ContractAssetsAndLiabilitiesTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ContractWithCustomerAssetAndLiabilityAbstract" xlink:label="loc_us-gaap_ContractWithCustomerAssetAndLiabilityAbstract_5306E807EA0D565299CF2A0A9C92256D" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ContractWithCustomerAssetAndLiabilityTableTextBlock" xlink:label="loc_us-gaap_ContractWithCustomerAssetAndLiabilityTableTextBlock_63EC784FF9015765837EC73FAC1C6685" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ContractWithCustomerAssetAndLiabilityAbstract_5306E807EA0D565299CF2A0A9C92256D" xlink:to="loc_us-gaap_ContractWithCustomerAssetAndLiabilityTableTextBlock_63EC784FF9015765837EC73FAC1C6685" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/CoverPage" xlink:type="extended">
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_CoverAbstract" xlink:label="loc_dei_CoverAbstract_7F2E6B087F155F2E8477262696F40445" xlink:type="locator" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_DocumentType" xlink:label="loc_dei_DocumentType_F2AFA829C85658699BF85BEE3BF58511" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_7F2E6B087F155F2E8477262696F40445" xlink:to="loc_dei_DocumentType_F2AFA829C85658699BF85BEE3BF58511" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_DocumentQuarterlyReport" xlink:label="loc_dei_DocumentQuarterlyReport_40478010B5F55FCEB75E7555EBFCF193" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_7F2E6B087F155F2E8477262696F40445" xlink:to="loc_dei_DocumentQuarterlyReport_40478010B5F55FCEB75E7555EBFCF193" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_DocumentPeriodEndDate" xlink:label="loc_dei_DocumentPeriodEndDate_DAAAD53D31EB52CB901157AD5A26B847" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_7F2E6B087F155F2E8477262696F40445" xlink:to="loc_dei_DocumentPeriodEndDate_DAAAD53D31EB52CB901157AD5A26B847" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_DocumentTransitionReport" xlink:label="loc_dei_DocumentTransitionReport_F60BAFEAEE8A5A2BA6336250EF926B75" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_7F2E6B087F155F2E8477262696F40445" xlink:to="loc_dei_DocumentTransitionReport_F60BAFEAEE8A5A2BA6336250EF926B75" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityFileNumber" xlink:label="loc_dei_EntityFileNumber_D848A32BDC815D2D9B0F5F26D1BE6855" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_7F2E6B087F155F2E8477262696F40445" xlink:to="loc_dei_EntityFileNumber_D848A32BDC815D2D9B0F5F26D1BE6855" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityRegistrantName" xlink:label="loc_dei_EntityRegistrantName_817A50053AE85EE5A078B01CC9F9335E" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_7F2E6B087F155F2E8477262696F40445" xlink:to="loc_dei_EntityRegistrantName_817A50053AE85EE5A078B01CC9F9335E" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityIncorporationStateCountryCode" xlink:label="loc_dei_EntityIncorporationStateCountryCode_EEF2270DA9A9517182C82775B8947A8B" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_7F2E6B087F155F2E8477262696F40445" xlink:to="loc_dei_EntityIncorporationStateCountryCode_EEF2270DA9A9517182C82775B8947A8B" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityTaxIdentificationNumber" xlink:label="loc_dei_EntityTaxIdentificationNumber_CDDB89592BB15366B7DF3B7B0D48BB40" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_7F2E6B087F155F2E8477262696F40445" xlink:to="loc_dei_EntityTaxIdentificationNumber_CDDB89592BB15366B7DF3B7B0D48BB40" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityAddressAddressLine1" xlink:label="loc_dei_EntityAddressAddressLine1_A3F50F0651BA5CCDBF4964B9EEB0FA57" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_7F2E6B087F155F2E8477262696F40445" xlink:to="loc_dei_EntityAddressAddressLine1_A3F50F0651BA5CCDBF4964B9EEB0FA57" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityAddressCityOrTown" xlink:label="loc_dei_EntityAddressCityOrTown_F8C5A775B16055EE8993A2A0A70DC1D8" xlink:type="locator" />
    <link:presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_7F2E6B087F155F2E8477262696F40445" xlink:to="loc_dei_EntityAddressCityOrTown_F8C5A775B16055EE8993A2A0A70DC1D8" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityAddressCountry" xlink:label="loc_dei_EntityAddressCountry_F89C5E848C3450D390063FD778F2CBE9" xlink:type="locator" />
    <link:presentationArc order="11" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_7F2E6B087F155F2E8477262696F40445" xlink:to="loc_dei_EntityAddressCountry_F89C5E848C3450D390063FD778F2CBE9" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityAddressPostalZipCode" xlink:label="loc_dei_EntityAddressPostalZipCode_184FB783DEF65CF0BEF9E5419C0EA0BB" xlink:type="locator" />
    <link:presentationArc order="12" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_7F2E6B087F155F2E8477262696F40445" xlink:to="loc_dei_EntityAddressPostalZipCode_184FB783DEF65CF0BEF9E5419C0EA0BB" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_CityAreaCode" xlink:label="loc_dei_CityAreaCode_E9B7C58C9C695A4C80E1A987EA4764CC" xlink:type="locator" />
    <link:presentationArc order="13" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_7F2E6B087F155F2E8477262696F40445" xlink:to="loc_dei_CityAreaCode_E9B7C58C9C695A4C80E1A987EA4764CC" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_LocalPhoneNumber" xlink:label="loc_dei_LocalPhoneNumber_35C925E4E8F45271B722554CD1A9B8D8" xlink:type="locator" />
    <link:presentationArc order="14" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_7F2E6B087F155F2E8477262696F40445" xlink:to="loc_dei_LocalPhoneNumber_35C925E4E8F45271B722554CD1A9B8D8" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityCurrentReportingStatus" xlink:label="loc_dei_EntityCurrentReportingStatus_7A37E93871C55069B6C26832861A4228" xlink:type="locator" />
    <link:presentationArc order="15" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_7F2E6B087F155F2E8477262696F40445" xlink:to="loc_dei_EntityCurrentReportingStatus_7A37E93871C55069B6C26832861A4228" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityInteractiveDataCurrent" xlink:label="loc_dei_EntityInteractiveDataCurrent_0F92630046095C19BA9E7B89258F7A79" xlink:type="locator" />
    <link:presentationArc order="16" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_7F2E6B087F155F2E8477262696F40445" xlink:to="loc_dei_EntityInteractiveDataCurrent_0F92630046095C19BA9E7B89258F7A79" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityFilerCategory" xlink:label="loc_dei_EntityFilerCategory_DF94E9E9917B5277A9FE92A1C713ACF4" xlink:type="locator" />
    <link:presentationArc order="17" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_7F2E6B087F155F2E8477262696F40445" xlink:to="loc_dei_EntityFilerCategory_DF94E9E9917B5277A9FE92A1C713ACF4" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntitySmallBusiness" xlink:label="loc_dei_EntitySmallBusiness_711D6E51F80E5C3D899093AAB19345A0" xlink:type="locator" />
    <link:presentationArc order="18" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_7F2E6B087F155F2E8477262696F40445" xlink:to="loc_dei_EntitySmallBusiness_711D6E51F80E5C3D899093AAB19345A0" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityEmergingGrowthCompany" xlink:label="loc_dei_EntityEmergingGrowthCompany_602C546477075434B23EC896D6A956C5" xlink:type="locator" />
    <link:presentationArc order="19" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_7F2E6B087F155F2E8477262696F40445" xlink:to="loc_dei_EntityEmergingGrowthCompany_602C546477075434B23EC896D6A956C5" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityShellCompany" xlink:label="loc_dei_EntityShellCompany_83174A0F400E59E980CD058C3613E263" xlink:type="locator" />
    <link:presentationArc order="20" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_7F2E6B087F155F2E8477262696F40445" xlink:to="loc_dei_EntityShellCompany_83174A0F400E59E980CD058C3613E263" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_Security12bTitle" xlink:label="loc_dei_Security12bTitle_AC5EBA2FC3D455FA9A4C44A67359BF44" xlink:type="locator" />
    <link:presentationArc order="21" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_7F2E6B087F155F2E8477262696F40445" xlink:to="loc_dei_Security12bTitle_AC5EBA2FC3D455FA9A4C44A67359BF44" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_TradingSymbol" xlink:label="loc_dei_TradingSymbol_9B688EFC7FFC583C8A2D3F2538D8C059" xlink:type="locator" />
    <link:presentationArc order="22" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_7F2E6B087F155F2E8477262696F40445" xlink:to="loc_dei_TradingSymbol_9B688EFC7FFC583C8A2D3F2538D8C059" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_SecurityExchangeName" xlink:label="loc_dei_SecurityExchangeName_ECF2C482C952529F9F5FB00C596AE7C0" xlink:type="locator" />
    <link:presentationArc order="23" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_7F2E6B087F155F2E8477262696F40445" xlink:to="loc_dei_SecurityExchangeName_ECF2C482C952529F9F5FB00C596AE7C0" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityCommonStockSharesOutstanding" xlink:label="loc_dei_EntityCommonStockSharesOutstanding_1282C50CA6975EF4B5769B363F8BEAF0" xlink:type="locator" />
    <link:presentationArc order="24" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_7F2E6B087F155F2E8477262696F40445" xlink:to="loc_dei_EntityCommonStockSharesOutstanding_1282C50CA6975EF4B5769B363F8BEAF0" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_AmendmentFlag" xlink:label="loc_dei_AmendmentFlag_B84C311A9BEA5CCAB0AA6E53E8E2E02E" xlink:type="locator" />
    <link:presentationArc order="25" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_7F2E6B087F155F2E8477262696F40445" xlink:to="loc_dei_AmendmentFlag_B84C311A9BEA5CCAB0AA6E53E8E2E02E" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_DocumentFiscalYearFocus" xlink:label="loc_dei_DocumentFiscalYearFocus_492E0F130C8C554EA7DA18F037465685" xlink:type="locator" />
    <link:presentationArc order="26" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_7F2E6B087F155F2E8477262696F40445" xlink:to="loc_dei_DocumentFiscalYearFocus_492E0F130C8C554EA7DA18F037465685" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_DocumentFiscalPeriodFocus" xlink:label="loc_dei_DocumentFiscalPeriodFocus_0A1318AF59FE5B369EC6DCAED663605A" xlink:type="locator" />
    <link:presentationArc order="27" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_7F2E6B087F155F2E8477262696F40445" xlink:to="loc_dei_DocumentFiscalPeriodFocus_0A1318AF59FE5B369EC6DCAED663605A" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityCentralIndexKey" xlink:label="loc_dei_EntityCentralIndexKey_5C7AA68D402F51C1B8614907D1E3106E" xlink:type="locator" />
    <link:presentationArc order="28" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_7F2E6B087F155F2E8477262696F40445" xlink:to="loc_dei_EntityCentralIndexKey_5C7AA68D402F51C1B8614907D1E3106E" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_CurrentFiscalYearEndDate" xlink:label="loc_dei_CurrentFiscalYearEndDate_AB3E5FD24D9656818CE82C9CB58BB0C6" xlink:type="locator" />
    <link:presentationArc order="29" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_7F2E6B087F155F2E8477262696F40445" xlink:to="loc_dei_CurrentFiscalYearEndDate_AB3E5FD24D9656818CE82C9CB58BB0C6" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/Debt" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtDisclosureAbstract" xlink:label="loc_us-gaap_DebtDisclosureAbstract_CFF8680683B25DDAA70B362A8546E9DA" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtDisclosureTextBlock" xlink:label="loc_us-gaap_DebtDisclosureTextBlock_CCEF082840AC5CD3B09DBC442066E679" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_CFF8680683B25DDAA70B362A8546E9DA" xlink:to="loc_us-gaap_DebtDisclosureTextBlock_CCEF082840AC5CD3B09DBC442066E679" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/DebtComponentsOfTotalIndebtednessDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtDisclosureAbstract" xlink:label="loc_us-gaap_DebtDisclosureAbstract_5A667131B4481FA13708690312A10456" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtInstrumentTable" xlink:label="loc_us-gaap_DebtInstrumentTable_5634692A340FEF6F4092690312A16270" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_5A667131B4481FA13708690312A10456" xlink:to="loc_us-gaap_DebtInstrumentTable_5634692A340FEF6F4092690312A16270" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtInstrumentAxis" xlink:label="loc_us-gaap_DebtInstrumentAxis_D8487A04B962B3F4E2A4690312A2EEF7" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_5634692A340FEF6F4092690312A16270" xlink:to="loc_us-gaap_DebtInstrumentAxis_D8487A04B962B3F4E2A4690312A2EEF7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtInstrumentNameDomain" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_082432964A4724101292690312A3CC67" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentAxis_D8487A04B962B3F4E2A4690312A2EEF7" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_082432964A4724101292690312A3CC67" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_SevenPointTwoFivePercentSeniorNotesDueTwoThousandTwentyTwoMember" xlink:label="loc_endp_SevenPointTwoFivePercentSeniorNotesDueTwoThousandTwentyTwoMember_4972A6A4526BBC9866B7690312A3BC1F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_082432964A4724101292690312A3CC67" xlink:to="loc_endp_SevenPointTwoFivePercentSeniorNotesDueTwoThousandTwentyTwoMember_4972A6A4526BBC9866B7690312A3BC1F" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_FivePointSevenFiveSeniorNotesDueOnTwoThousandTwentyTwoMember" xlink:label="loc_endp_FivePointSevenFiveSeniorNotesDueOnTwoThousandTwentyTwoMember_6069E4532701757DB0CD690312A38048" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_082432964A4724101292690312A3CC67" xlink:to="loc_endp_FivePointSevenFiveSeniorNotesDueOnTwoThousandTwentyTwoMember_6069E4532701757DB0CD690312A38048" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_FivePointThreeSevenFiveSeniorNotesDueOnTwoThousandTwentyThreeMember" xlink:label="loc_endp_FivePointThreeSevenFiveSeniorNotesDueOnTwoThousandTwentyThreeMember_FE0D73A116CA775E7197690312A3C0E6" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_082432964A4724101292690312A3CC67" xlink:to="loc_endp_FivePointThreeSevenFiveSeniorNotesDueOnTwoThousandTwentyThreeMember_FE0D73A116CA775E7197690312A3C0E6" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_SixPointZeroPercentSeniorNotesDueTwoThousandTwentyThreeMember" xlink:label="loc_endp_SixPointZeroPercentSeniorNotesDueTwoThousandTwentyThreeMember_406F33D49A69D338221A690312A304E4" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_082432964A4724101292690312A3CC67" xlink:to="loc_endp_SixPointZeroPercentSeniorNotesDueTwoThousandTwentyThreeMember_406F33D49A69D338221A690312A304E4" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_FivePointEightSevenFivePercentSeniorSecuredNotesDueTwentyTwentyFourMember" xlink:label="loc_endp_FivePointEightSevenFivePercentSeniorSecuredNotesDueTwentyTwentyFourMember_FCE8BE920B816B554917690312A46D39" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_082432964A4724101292690312A3CC67" xlink:to="loc_endp_FivePointEightSevenFivePercentSeniorSecuredNotesDueTwentyTwentyFourMember_FCE8BE920B816B554917690312A46D39" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_A6.00SeniorNotesDue2025Member" xlink:label="loc_endp_A6.00SeniorNotesDue2025Member_11C6236353702E6A4997690312A4915C" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_082432964A4724101292690312A3CC67" xlink:to="loc_endp_A6.00SeniorNotesDue2025Member_11C6236353702E6A4997690312A4915C" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_SevenPointFivePercentSeniorSecuredNotesDueTwentyTwentySevenMember" xlink:label="loc_endp_SevenPointFivePercentSeniorSecuredNotesDueTwentyTwentySevenMember_54FA0271135A42D6BEC8690312A40E43" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_082432964A4724101292690312A3CC67" xlink:to="loc_endp_SevenPointFivePercentSeniorSecuredNotesDueTwentyTwentySevenMember_54FA0271135A42D6BEC8690312A40E43" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_TermLoanBFacilityDueTwoThousandTwentyFourMember" xlink:label="loc_endp_TermLoanBFacilityDueTwoThousandTwentyFourMember_5293FAD7EADC6198CFF6690312A420A1" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_082432964A4724101292690312A3CC67" xlink:to="loc_endp_TermLoanBFacilityDueTwoThousandTwentyFourMember_5293FAD7EADC6198CFF6690312A420A1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CreditFacilityAxis" xlink:label="loc_us-gaap_CreditFacilityAxis_B46443F24788ECEC862C690312A2F8E5" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_5634692A340FEF6F4092690312A16270" xlink:to="loc_us-gaap_CreditFacilityAxis_B46443F24788ECEC862C690312A2F8E5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CreditFacilityDomain" xlink:label="loc_us-gaap_CreditFacilityDomain_1F189A64660E0AD9EC54690312A2B81C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CreditFacilityAxis_B46443F24788ECEC862C690312A2F8E5" xlink:to="loc_us-gaap_CreditFacilityDomain_1F189A64660E0AD9EC54690312A2B81C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RevolvingCreditFacilityMember" xlink:label="loc_us-gaap_RevolvingCreditFacilityMember_B7FD387AA71D39B1069E690312A29A0C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CreditFacilityDomain_1F189A64660E0AD9EC54690312A2B81C" xlink:to="loc_us-gaap_RevolvingCreditFacilityMember_B7FD387AA71D39B1069E690312A29A0C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtInstrumentLineItems" xlink:label="loc_us-gaap_DebtInstrumentLineItems_5FF84D26FDB1A9D0873F690312A47706" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_5634692A340FEF6F4092690312A16270" xlink:to="loc_us-gaap_DebtInstrumentLineItems_5FF84D26FDB1A9D0873F690312A47706" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtInstrumentInterestRateEffectivePercentage" xlink:label="loc_us-gaap_DebtInstrumentInterestRateEffectivePercentage_63CBA130F88E5A46086E690312A5C20B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_5FF84D26FDB1A9D0873F690312A47706" xlink:to="loc_us-gaap_DebtInstrumentInterestRateEffectivePercentage_63CBA130F88E5A46086E690312A5C20B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtInstrumentFaceAmount" xlink:label="loc_us-gaap_DebtInstrumentFaceAmount_3ED1667FBE5D8F9A46D5690312A5FE19" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_5FF84D26FDB1A9D0873F690312A47706" xlink:to="loc_us-gaap_DebtInstrumentFaceAmount_3ED1667FBE5D8F9A46D5690312A5FE19" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LongTermDebt" xlink:label="loc_us-gaap_LongTermDebt_9FB1B2136DADD140A17D690312A5DAD8" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_5FF84D26FDB1A9D0873F690312A47706" xlink:to="loc_us-gaap_LongTermDebt_9FB1B2136DADD140A17D690312A5DAD8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LongTermDebtCurrent" xlink:label="loc_us-gaap_LongTermDebtCurrent_DD3F8605F44CF2B4BE33690312A5279B" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_5FF84D26FDB1A9D0873F690312A47706" xlink:to="loc_us-gaap_LongTermDebtCurrent_DD3F8605F44CF2B4BE33690312A5279B" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_DebtInstrumentFaceAmountExcludingCurrentMaturities" xlink:label="loc_endp_DebtInstrumentFaceAmountExcludingCurrentMaturities_DC06D4ECB65A779FDC1F690312A5EA62" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_5FF84D26FDB1A9D0873F690312A47706" xlink:to="loc_endp_DebtInstrumentFaceAmountExcludingCurrentMaturities_DC06D4ECB65A779FDC1F690312A5EA62" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LongTermDebtNoncurrent" xlink:label="loc_us-gaap_LongTermDebtNoncurrent_2AF4801A88D247623F46690312A5E92F" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_5FF84D26FDB1A9D0873F690312A47706" xlink:to="loc_us-gaap_LongTermDebtNoncurrent_2AF4801A88D247623F46690312A5E92F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtInstrumentInterestRateStatedPercentage" xlink:label="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_89D27C4AD041F333FC37690312A68C79" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_5FF84D26FDB1A9D0873F690312A47706" xlink:to="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_89D27C4AD041F333FC37690312A68C79" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LongTermDebtFairValue" xlink:label="loc_us-gaap_LongTermDebtFairValue_8D098F63D38A57CC1063690312A6EA60" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_5FF84D26FDB1A9D0873F690312A47706" xlink:to="loc_us-gaap_LongTermDebtFairValue_8D098F63D38A57CC1063690312A6EA60" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/DebtCreditFacilityNarrativeDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtDisclosureAbstract" xlink:label="loc_us-gaap_DebtDisclosureAbstract_B16D451AAB825CA18875C5459225F432" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LineOfCreditFacilityTable" xlink:label="loc_us-gaap_LineOfCreditFacilityTable_6503416D2A0B56B88233B797FB955573" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_B16D451AAB825CA18875C5459225F432" xlink:to="loc_us-gaap_LineOfCreditFacilityTable_6503416D2A0B56B88233B797FB955573" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtInstrumentAxis" xlink:label="loc_us-gaap_DebtInstrumentAxis_D7BBB1C41AE35FD091130A573B334080" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityTable_6503416D2A0B56B88233B797FB955573" xlink:to="loc_us-gaap_DebtInstrumentAxis_D7BBB1C41AE35FD091130A573B334080" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtInstrumentNameDomain" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_38A4DF9413FD5600B1672C42B9FA0E02" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentAxis_D7BBB1C41AE35FD091130A573B334080" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_38A4DF9413FD5600B1672C42B9FA0E02" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_A2017CreditAgreementMember" xlink:label="loc_endp_A2017CreditAgreementMember_598AB322CF61570CA9027897148FF588" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_38A4DF9413FD5600B1672C42B9FA0E02" xlink:to="loc_endp_A2017CreditAgreementMember_598AB322CF61570CA9027897148FF588" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CreditFacilityAxis" xlink:label="loc_us-gaap_CreditFacilityAxis_5CA1F69FB90152C4A7FAAD0D0B198347" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityTable_6503416D2A0B56B88233B797FB955573" xlink:to="loc_us-gaap_CreditFacilityAxis_5CA1F69FB90152C4A7FAAD0D0B198347" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CreditFacilityDomain" xlink:label="loc_us-gaap_CreditFacilityDomain_4596C41D4B5455F79C7A704B06B45492" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CreditFacilityAxis_5CA1F69FB90152C4A7FAAD0D0B198347" xlink:to="loc_us-gaap_CreditFacilityDomain_4596C41D4B5455F79C7A704B06B45492" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RevolvingCreditFacilityMember" xlink:label="loc_us-gaap_RevolvingCreditFacilityMember_DD70327344875B828E51E474C49D6A87" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CreditFacilityDomain_4596C41D4B5455F79C7A704B06B45492" xlink:to="loc_us-gaap_RevolvingCreditFacilityMember_DD70327344875B828E51E474C49D6A87" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LineOfCreditFacilityLineItems" xlink:label="loc_us-gaap_LineOfCreditFacilityLineItems_AA7FDFE48A73556991A6B0FF5A494309" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityTable_6503416D2A0B56B88233B797FB955573" xlink:to="loc_us-gaap_LineOfCreditFacilityLineItems_AA7FDFE48A73556991A6B0FF5A494309" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity" xlink:label="loc_us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity_B3633529189954569D06B86FCB8FEE6F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityLineItems_AA7FDFE48A73556991A6B0FF5A494309" xlink:to="loc_us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity_B3633529189954569D06B86FCB8FEE6F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ProceedsFromLinesOfCredit" xlink:label="loc_us-gaap_ProceedsFromLinesOfCredit_D63145E9A69C504E89F27F5A4A67E848" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityLineItems_AA7FDFE48A73556991A6B0FF5A494309" xlink:to="loc_us-gaap_ProceedsFromLinesOfCredit_D63145E9A69C504E89F27F5A4A67E848" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LineOfCreditFacilityRemainingBorrowingCapacity" xlink:label="loc_us-gaap_LineOfCreditFacilityRemainingBorrowingCapacity_01FAFEFA5B645B45892A6BE55D549985" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityLineItems_AA7FDFE48A73556991A6B0FF5A494309" xlink:to="loc_us-gaap_LineOfCreditFacilityRemainingBorrowingCapacity_01FAFEFA5B645B45892A6BE55D549985" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/DebtMarch2019RefinancingDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtDisclosureAbstract" xlink:label="loc_us-gaap_DebtDisclosureAbstract_DA6D4B59F0CD25007B9F2370E6129784" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtInstrumentTable" xlink:label="loc_us-gaap_DebtInstrumentTable_D9367EFAF4BAFDE2DFDA2370E612B7EB" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_DA6D4B59F0CD25007B9F2370E6129784" xlink:to="loc_us-gaap_DebtInstrumentTable_D9367EFAF4BAFDE2DFDA2370E612B7EB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CreditFacilityAxis" xlink:label="loc_us-gaap_CreditFacilityAxis_80DF887327041798E5A02370E6120759" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_D9367EFAF4BAFDE2DFDA2370E612B7EB" xlink:to="loc_us-gaap_CreditFacilityAxis_80DF887327041798E5A02370E6120759" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CreditFacilityDomain" xlink:label="loc_us-gaap_CreditFacilityDomain_EC0AA28F9044103F519D2370E612B538" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CreditFacilityAxis_80DF887327041798E5A02370E6120759" xlink:to="loc_us-gaap_CreditFacilityDomain_EC0AA28F9044103F519D2370E612B538" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RevolvingCreditFacilityMember" xlink:label="loc_us-gaap_RevolvingCreditFacilityMember_9F9C12A79F5679D655DE2370E61377F4" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CreditFacilityDomain_EC0AA28F9044103F519D2370E612B538" xlink:to="loc_us-gaap_RevolvingCreditFacilityMember_9F9C12A79F5679D655DE2370E61377F4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LongtermDebtTypeAxis" xlink:label="loc_us-gaap_LongtermDebtTypeAxis_8B5813FF857BDD82A4192370E613B680" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_D9367EFAF4BAFDE2DFDA2370E612B7EB" xlink:to="loc_us-gaap_LongtermDebtTypeAxis_8B5813FF857BDD82A4192370E613B680" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LongtermDebtTypeDomain" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_23DECAFFCA0ED21F1B542370E613F31C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_8B5813FF857BDD82A4192370E613B680" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_23DECAFFCA0ED21F1B542370E613F31C" xlink:type="arc" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_23DECAFFCA0ED21F1B542370E613F31C" xlink:to="loc_us-gaap_RevolvingCreditFacilityMember_9F9C12A79F5679D655DE2370E61377F4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SeniorNotesMember" xlink:label="loc_us-gaap_SeniorNotesMember_C41C0F7BEC722872D44D2370E614BA8F" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_23DECAFFCA0ED21F1B542370E613F31C" xlink:to="loc_us-gaap_SeniorNotesMember_C41C0F7BEC722872D44D2370E614BA8F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtInstrumentAxis" xlink:label="loc_us-gaap_DebtInstrumentAxis_FEB738C625ADB16A31A22370E6143D14" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_D9367EFAF4BAFDE2DFDA2370E612B7EB" xlink:to="loc_us-gaap_DebtInstrumentAxis_FEB738C625ADB16A31A22370E6143D14" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtInstrumentNameDomain" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_1DE9CD516169353FDF652370E61453CC" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentAxis_FEB738C625ADB16A31A22370E6143D14" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_1DE9CD516169353FDF652370E61453CC" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_SevenPointFivePercentSeniorSecuredNotesDueTwentyTwentySevenMember" xlink:label="loc_endp_SevenPointFivePercentSeniorSecuredNotesDueTwentyTwentySevenMember_9A725F952F57742D6D4A2370E614E4F1" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_1DE9CD516169353FDF652370E61453CC" xlink:to="loc_endp_SevenPointFivePercentSeniorSecuredNotesDueTwentyTwentySevenMember_9A725F952F57742D6D4A2370E614E4F1" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_SevenPointTwoFivePercentSeniorNotesDueTwoThousandTwentyTwoMember" xlink:label="loc_endp_SevenPointTwoFivePercentSeniorNotesDueTwoThousandTwentyTwoMember_7C43E7815DFE25BFCAAF2370E615F089" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_1DE9CD516169353FDF652370E61453CC" xlink:to="loc_endp_SevenPointTwoFivePercentSeniorNotesDueTwoThousandTwentyTwoMember_7C43E7815DFE25BFCAAF2370E615F089" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_FivePointSevenFiveSeniorNotesDueOnTwoThousandTwentyTwoMember" xlink:label="loc_endp_FivePointSevenFiveSeniorNotesDueOnTwoThousandTwentyTwoMember_FE492342B9E377BC4F6D2370E615F4E9" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_1DE9CD516169353FDF652370E61453CC" xlink:to="loc_endp_FivePointSevenFiveSeniorNotesDueOnTwoThousandTwentyTwoMember_FE492342B9E377BC4F6D2370E615F4E9" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_A2017CreditAgreementMember" xlink:label="loc_endp_A2017CreditAgreementMember_659519348ACD4C65C4762370E61A08F2" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_1DE9CD516169353FDF652370E61453CC" xlink:to="loc_endp_A2017CreditAgreementMember_659519348ACD4C65C4762370E61A08F2" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_FivePointThreeSevenFiveSeniorNotesDueOnTwoThousandTwentyThreeMember" xlink:label="loc_endp_FivePointThreeSevenFiveSeniorNotesDueOnTwoThousandTwentyThreeMember_6C2A921668238F0B27B92370E61AFE65" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_1DE9CD516169353FDF652370E61453CC" xlink:to="loc_endp_FivePointThreeSevenFiveSeniorNotesDueOnTwoThousandTwentyThreeMember_6C2A921668238F0B27B92370E61AFE65" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_SixPointZeroPercentSeniorNotesDueTwoThousandTwentyThreeMember" xlink:label="loc_endp_SixPointZeroPercentSeniorNotesDueTwoThousandTwentyThreeMember_E5967C1CB43CC9C09DBB2370E61AA957" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_1DE9CD516169353FDF652370E61453CC" xlink:to="loc_endp_SixPointZeroPercentSeniorNotesDueTwoThousandTwentyThreeMember_E5967C1CB43CC9C09DBB2370E61AA957" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_NoteRepurchasesMember" xlink:label="loc_endp_NoteRepurchasesMember_93D36BB2EDBFDF9F8FAE2370E61BA454" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_1DE9CD516169353FDF652370E61453CC" xlink:to="loc_endp_NoteRepurchasesMember_93D36BB2EDBFDF9F8FAE2370E61BA454" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtInstrumentRedemptionPeriodAxis" xlink:label="loc_us-gaap_DebtInstrumentRedemptionPeriodAxis_03021BE1463FC9A2AE0F2370E61B92CD" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_D9367EFAF4BAFDE2DFDA2370E612B7EB" xlink:to="loc_us-gaap_DebtInstrumentRedemptionPeriodAxis_03021BE1463FC9A2AE0F2370E61B92CD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtInstrumentRedemptionPeriodDomain" xlink:label="loc_us-gaap_DebtInstrumentRedemptionPeriodDomain_0D6277769F901B86E0AB2370E61B3EE0" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentRedemptionPeriodAxis_03021BE1463FC9A2AE0F2370E61B92CD" xlink:to="loc_us-gaap_DebtInstrumentRedemptionPeriodDomain_0D6277769F901B86E0AB2370E61B3EE0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtInstrumentRedemptionPeriodOneMember" xlink:label="loc_us-gaap_DebtInstrumentRedemptionPeriodOneMember_639537C2A9D7491132BB2370E61BF1BE" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentRedemptionPeriodDomain_0D6277769F901B86E0AB2370E61B3EE0" xlink:to="loc_us-gaap_DebtInstrumentRedemptionPeriodOneMember_639537C2A9D7491132BB2370E61BF1BE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtInstrumentRedemptionPeriodTwoMember" xlink:label="loc_us-gaap_DebtInstrumentRedemptionPeriodTwoMember_31BCDA0C280669FB5CAA2370E61B57B4" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentRedemptionPeriodDomain_0D6277769F901B86E0AB2370E61B3EE0" xlink:to="loc_us-gaap_DebtInstrumentRedemptionPeriodTwoMember_31BCDA0C280669FB5CAA2370E61B57B4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtInstrumentRedemptionPeriodThreeMember" xlink:label="loc_us-gaap_DebtInstrumentRedemptionPeriodThreeMember_385D6CCD972BA88F10CE2370E61CBF01" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentRedemptionPeriodDomain_0D6277769F901B86E0AB2370E61B3EE0" xlink:to="loc_us-gaap_DebtInstrumentRedemptionPeriodThreeMember_385D6CCD972BA88F10CE2370E61CBF01" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtInstrumentRedemptionPeriodFourMember" xlink:label="loc_us-gaap_DebtInstrumentRedemptionPeriodFourMember_B072CA2383BBB35E38B92370E61CE91F" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentRedemptionPeriodDomain_0D6277769F901B86E0AB2370E61B3EE0" xlink:to="loc_us-gaap_DebtInstrumentRedemptionPeriodFourMember_B072CA2383BBB35E38B92370E61CE91F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtInstrumentRedemptionPeriodFiveMember" xlink:label="loc_us-gaap_DebtInstrumentRedemptionPeriodFiveMember_CE979031101F61B4993F2370E61CAB1B" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentRedemptionPeriodDomain_0D6277769F901B86E0AB2370E61B3EE0" xlink:to="loc_us-gaap_DebtInstrumentRedemptionPeriodFiveMember_CE979031101F61B4993F2370E61CAB1B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_RangeAxis" xlink:label="loc_srt_RangeAxis_F180E033F42C06292B192370E61C9764" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_D9367EFAF4BAFDE2DFDA2370E612B7EB" xlink:to="loc_srt_RangeAxis_F180E033F42C06292B192370E61C9764" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_RangeMember" xlink:label="loc_srt_RangeMember_EED36C1D0715F60779D62370E61C4FF0" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeAxis_F180E033F42C06292B192370E61C9764" xlink:to="loc_srt_RangeMember_EED36C1D0715F60779D62370E61C4FF0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_MinimumMember" xlink:label="loc_srt_MinimumMember_05EA7D93A5946DC8D2152370E61DC695" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_EED36C1D0715F60779D62370E61C4FF0" xlink:to="loc_srt_MinimumMember_05EA7D93A5946DC8D2152370E61DC695" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_MaximumMember" xlink:label="loc_srt_MaximumMember_0C07295D55858C4EDFA02370E61D6009" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_EED36C1D0715F60779D62370E61C4FF0" xlink:to="loc_srt_MaximumMember_0C07295D55858C4EDFA02370E61D6009" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtInstrumentLineItems" xlink:label="loc_us-gaap_DebtInstrumentLineItems_00B73431C32810F742752370E61D0925" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_D9367EFAF4BAFDE2DFDA2370E612B7EB" xlink:to="loc_us-gaap_DebtInstrumentLineItems_00B73431C32810F742752370E61D0925" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtInstrumentFaceAmount" xlink:label="loc_us-gaap_DebtInstrumentFaceAmount_9CF2B5C49E01F633E4F82370E61D9E2A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_00B73431C32810F742752370E61D0925" xlink:to="loc_us-gaap_DebtInstrumentFaceAmount_9CF2B5C49E01F633E4F82370E61D9E2A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtInstrumentRepurchasedFaceAmount" xlink:label="loc_us-gaap_DebtInstrumentRepurchasedFaceAmount_74547DAB9B79B4E1A9E92370E61E5916" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_00B73431C32810F742752370E61D0925" xlink:to="loc_us-gaap_DebtInstrumentRepurchasedFaceAmount_74547DAB9B79B4E1A9E92370E61E5916" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RepaymentsOfLongTermDebt" xlink:label="loc_us-gaap_RepaymentsOfLongTermDebt_BDD8CECDBA92813CFDD02370E61E1237" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_00B73431C32810F742752370E61D0925" xlink:to="loc_us-gaap_RepaymentsOfLongTermDebt_BDD8CECDBA92813CFDD02370E61E1237" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtInstrumentInterestRateStatedPercentage" xlink:label="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_4CCFC83C915B53230BE62370E61E3877" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_00B73431C32810F742752370E61D0925" xlink:to="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_4CCFC83C915B53230BE62370E61E3877" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_DebtInstrumentCommitmentsNotExtendedAmount" xlink:label="loc_endp_DebtInstrumentCommitmentsNotExtendedAmount_386635D31B8C703DEBA72370E61E08F8" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_00B73431C32810F742752370E61D0925" xlink:to="loc_endp_DebtInstrumentCommitmentsNotExtendedAmount_386635D31B8C703DEBA72370E61E08F8" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_DebtInstrumentSecuredLeverageRatio" xlink:label="loc_endp_DebtInstrumentSecuredLeverageRatio_82DED2C5905C53B94DBE2370E61E5048" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_00B73431C32810F742752370E61D0925" xlink:to="loc_endp_DebtInstrumentSecuredLeverageRatio_82DED2C5905C53B94DBE2370E61E5048" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtInstrumentRedemptionPricePercentage" xlink:label="loc_us-gaap_DebtInstrumentRedemptionPricePercentage_03362C3080898F989C612370E61EEA3C" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_00B73431C32810F742752370E61D0925" xlink:to="loc_us-gaap_DebtInstrumentRedemptionPricePercentage_03362C3080898F989C612370E61EEA3C" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_DebtInstrumentRedemptionPercentOfPrincipalAmountOutstanding" xlink:label="loc_endp_DebtInstrumentRedemptionPercentOfPrincipalAmountOutstanding_4A7CF08FE1BB04890B6B2370E61FEDAB" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_00B73431C32810F742752370E61D0925" xlink:to="loc_endp_DebtInstrumentRedemptionPercentOfPrincipalAmountOutstanding_4A7CF08FE1BB04890B6B2370E61FEDAB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ExtinguishmentOfDebtAmount" xlink:label="loc_us-gaap_ExtinguishmentOfDebtAmount_E1830D8B72F0F3E78AAD2370E61F65A3" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_00B73431C32810F742752370E61D0925" xlink:to="loc_us-gaap_ExtinguishmentOfDebtAmount_E1830D8B72F0F3E78AAD2370E61F65A3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_GainsLossesOnExtinguishmentOfDebtBeforeWriteOffOfDeferredDebtIssuanceCost" xlink:label="loc_us-gaap_GainsLossesOnExtinguishmentOfDebtBeforeWriteOffOfDeferredDebtIssuanceCost_53297D696DDAF6B921C52370E61FB2A5" xlink:type="locator" />
    <link:presentationArc order="10" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_00B73431C32810F742752370E61D0925" xlink:to="loc_us-gaap_GainsLossesOnExtinguishmentOfDebtBeforeWriteOffOfDeferredDebtIssuanceCost_53297D696DDAF6B921C52370E61FB2A5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_WriteOffOfDeferredDebtIssuanceCost" xlink:label="loc_us-gaap_WriteOffOfDeferredDebtIssuanceCost_9F7AB78938E74A0797AD2370E61F81F2" xlink:type="locator" />
    <link:presentationArc order="11" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_00B73431C32810F742752370E61D0925" xlink:to="loc_us-gaap_WriteOffOfDeferredDebtIssuanceCost_9F7AB78938E74A0797AD2370E61F81F2" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/DebtMaturitiesOnLongTermDebtForEachOfNextFiveYearsDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtDisclosureAbstract" xlink:label="loc_us-gaap_DebtDisclosureAbstract_791E373A097EFC629F6469A2CE2C6899" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtInstrumentTable" xlink:label="loc_us-gaap_DebtInstrumentTable_F2EA49BEC9C1341618B269A2CE2CCF8D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_791E373A097EFC629F6469A2CE2C6899" xlink:to="loc_us-gaap_DebtInstrumentTable_F2EA49BEC9C1341618B269A2CE2CCF8D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CreditFacilityAxis" xlink:label="loc_us-gaap_CreditFacilityAxis_56E15A7B909E90F3CFED69A2CE2C1BDD" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_F2EA49BEC9C1341618B269A2CE2CCF8D" xlink:to="loc_us-gaap_CreditFacilityAxis_56E15A7B909E90F3CFED69A2CE2C1BDD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CreditFacilityDomain" xlink:label="loc_us-gaap_CreditFacilityDomain_030B81151CF47AE34A8769A2CE2C28DB" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CreditFacilityAxis_56E15A7B909E90F3CFED69A2CE2C1BDD" xlink:to="loc_us-gaap_CreditFacilityDomain_030B81151CF47AE34A8769A2CE2C28DB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RevolvingCreditFacilityMember" xlink:label="loc_us-gaap_RevolvingCreditFacilityMember_6050E269740B3A21C8AB69A2CE2CAC51" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CreditFacilityDomain_030B81151CF47AE34A8769A2CE2C28DB" xlink:to="loc_us-gaap_RevolvingCreditFacilityMember_6050E269740B3A21C8AB69A2CE2CAC51" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LongtermDebtTypeAxis" xlink:label="loc_us-gaap_LongtermDebtTypeAxis_0FB69FBEF275163B51C469A2CE2CA1F0" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_F2EA49BEC9C1341618B269A2CE2CCF8D" xlink:to="loc_us-gaap_LongtermDebtTypeAxis_0FB69FBEF275163B51C469A2CE2CA1F0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LongtermDebtTypeDomain" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_C8AF20151CF63A44F25069A2CE2C58A0" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_0FB69FBEF275163B51C469A2CE2CA1F0" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_C8AF20151CF63A44F25069A2CE2C58A0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SeniorNotesMember" xlink:label="loc_us-gaap_SeniorNotesMember_4EB82BF4CB3CB60245AB69A2CE2C4D1B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_C8AF20151CF63A44F25069A2CE2C58A0" xlink:to="loc_us-gaap_SeniorNotesMember_4EB82BF4CB3CB60245AB69A2CE2C4D1B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtInstrumentAxis" xlink:label="loc_us-gaap_DebtInstrumentAxis_BF6DFC7C9E906BDDD78069A2CE2C076C" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_F2EA49BEC9C1341618B269A2CE2CCF8D" xlink:to="loc_us-gaap_DebtInstrumentAxis_BF6DFC7C9E906BDDD78069A2CE2C076C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtInstrumentNameDomain" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_CA718F15B6D4A43C80CC69A2CE2CE11E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentAxis_BF6DFC7C9E906BDDD78069A2CE2C076C" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_CA718F15B6D4A43C80CC69A2CE2CE11E" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_SeniorNotesMaturingDue2022Member" xlink:label="loc_endp_SeniorNotesMaturingDue2022Member_7A59FEFE53A70C2BCB6A69A2CE2CEBBB" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_CA718F15B6D4A43C80CC69A2CE2CE11E" xlink:to="loc_endp_SeniorNotesMaturingDue2022Member_7A59FEFE53A70C2BCB6A69A2CE2CEBBB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtInstrumentLineItems" xlink:label="loc_us-gaap_DebtInstrumentLineItems_DE9E685476A6DEEE366769A2CE2CCA31" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_F2EA49BEC9C1341618B269A2CE2CCF8D" xlink:to="loc_us-gaap_DebtInstrumentLineItems_DE9E685476A6DEEE366769A2CE2CCA31" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LongTermDebtByMaturityAbstract" xlink:label="loc_us-gaap_LongTermDebtByMaturityAbstract_6F8B3653B3DC9EFDC06469A2CE2CDAFD" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_DE9E685476A6DEEE366769A2CE2CCA31" xlink:to="loc_us-gaap_LongTermDebtByMaturityAbstract_6F8B3653B3DC9EFDC06469A2CE2CDAFD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInNextTwelveMonths" xlink:label="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInNextTwelveMonths_010E2FA44A1AA6B0AD306A0F34DD78D6" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongTermDebtByMaturityAbstract_6F8B3653B3DC9EFDC06469A2CE2CDAFD" xlink:to="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInNextTwelveMonths_010E2FA44A1AA6B0AD306A0F34DD78D6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearTwo" xlink:label="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearTwo_8264819EDB65A47CA72969A2CE2C67DF" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongTermDebtByMaturityAbstract_6F8B3653B3DC9EFDC06469A2CE2CDAFD" xlink:to="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearTwo_8264819EDB65A47CA72969A2CE2C67DF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearThree" xlink:label="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearThree_0E6025115274000792AF69A2CE2C7E83" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongTermDebtByMaturityAbstract_6F8B3653B3DC9EFDC06469A2CE2CDAFD" xlink:to="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearThree_0E6025115274000792AF69A2CE2C7E83" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFour" xlink:label="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFour_624A84E748460B4D288269A2CE2C9902" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongTermDebtByMaturityAbstract_6F8B3653B3DC9EFDC06469A2CE2CDAFD" xlink:to="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFour_624A84E748460B4D288269A2CE2C9902" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFive" xlink:label="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFive_1D2E050C353EA66A760669A2CE2CF1EF" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongTermDebtByMaturityAbstract_6F8B3653B3DC9EFDC06469A2CE2CDAFD" xlink:to="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFive_1D2E050C353EA66A760669A2CE2CF1EF" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_LongtermDebtMaturityRepaymentDeadline" xlink:label="loc_endp_LongtermDebtMaturityRepaymentDeadline_F1025BD010AF150DA44469A2CE2C3984" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_DE9E685476A6DEEE366769A2CE2CCA31" xlink:to="loc_endp_LongtermDebtMaturityRepaymentDeadline_F1025BD010AF150DA44469A2CE2C3984" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ExtinguishmentOfDebtAmount" xlink:label="loc_us-gaap_ExtinguishmentOfDebtAmount_CAF23E4EDEE95432AB8869A2CE2C1385" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_DE9E685476A6DEEE366769A2CE2CCA31" xlink:to="loc_us-gaap_ExtinguishmentOfDebtAmount_CAF23E4EDEE95432AB8869A2CE2C1385" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/DebtTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtDisclosureAbstract" xlink:label="loc_us-gaap_DebtDisclosureAbstract_27360F77F47C5DBBACAB065C18742947" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfDebtInstrumentsTextBlock" xlink:label="loc_us-gaap_ScheduleOfDebtInstrumentsTextBlock_7AD406E434785591A32D031EE4338606" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_27360F77F47C5DBBACAB065C18742947" xlink:to="loc_us-gaap_ScheduleOfDebtInstrumentsTextBlock_7AD406E434785591A32D031EE4338606" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfMaturitiesOfLongTermDebtTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfMaturitiesOfLongTermDebtTableTextBlock_E6C66E327450506F9372C319C75C6742" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_27360F77F47C5DBBACAB065C18742947" xlink:to="loc_us-gaap_ScheduleOfMaturitiesOfLongTermDebtTableTextBlock_E6C66E327450506F9372C319C75C6742" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/DiscontinuedOperations" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DiscontinuedOperationsAndDisposalGroupsAbstract" xlink:label="loc_us-gaap_DiscontinuedOperationsAndDisposalGroupsAbstract_B27EFED4EC0A53ADB80EE3B31FAF31E3" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DisposalGroupsIncludingDiscontinuedOperationsDisclosureTextBlock" xlink:label="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsDisclosureTextBlock_F2A59ADA95E856F6AC91960C6C5C5EB1" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DiscontinuedOperationsAndDisposalGroupsAbstract_B27EFED4EC0A53ADB80EE3B31FAF31E3" xlink:to="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsDisclosureTextBlock_F2A59ADA95E856F6AC91960C6C5C5EB1" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/DiscontinuedOperationsAstoraDiscontinuedOperationsDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DiscontinuedOperationsAndDisposalGroupsAbstract" xlink:label="loc_us-gaap_DiscontinuedOperationsAndDisposalGroupsAbstract_E68F4A0E90741E1B030E2D6DBB01AFC5" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable" xlink:label="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_61C0A2CA86A1A5D198B12D6DBB015009" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DiscontinuedOperationsAndDisposalGroupsAbstract_E68F4A0E90741E1B030E2D6DBB01AFC5" xlink:to="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_61C0A2CA86A1A5D198B12D6DBB015009" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DisposalGroupClassificationAxis" xlink:label="loc_us-gaap_DisposalGroupClassificationAxis_9AC26F5DA187724DC7882D6DBB01E3A2" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_61C0A2CA86A1A5D198B12D6DBB015009" xlink:to="loc_us-gaap_DisposalGroupClassificationAxis_9AC26F5DA187724DC7882D6DBB01E3A2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DisposalGroupClassificationDomain" xlink:label="loc_us-gaap_DisposalGroupClassificationDomain_855FC4A80CE4D4ECA4AB2D6DBB02D28C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisposalGroupClassificationAxis_9AC26F5DA187724DC7882D6DBB01E3A2" xlink:to="loc_us-gaap_DisposalGroupClassificationDomain_855FC4A80CE4D4ECA4AB2D6DBB02D28C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DiscontinuedOperationsDisposedOfByMeansOtherThanSaleAbandonmentMember" xlink:label="loc_us-gaap_DiscontinuedOperationsDisposedOfByMeansOtherThanSaleAbandonmentMember_98911870E6BB18236B232D6DBB02775B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisposalGroupClassificationDomain_855FC4A80CE4D4ECA4AB2D6DBB02D28C" xlink:to="loc_us-gaap_DiscontinuedOperationsDisposedOfByMeansOtherThanSaleAbandonmentMember_98911870E6BB18236B232D6DBB02775B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis" xlink:label="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_799EEDB0C5DE51F0962C2D6DBB026871" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_61C0A2CA86A1A5D198B12D6DBB015009" xlink:to="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_799EEDB0C5DE51F0962C2D6DBB026871" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain" xlink:label="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_C319D2606939300AE70F2D6DBB025729" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_799EEDB0C5DE51F0962C2D6DBB026871" xlink:to="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_C319D2606939300AE70F2D6DBB025729" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_AstoraMember" xlink:label="loc_endp_AstoraMember_D7B7EAD94E38A084148C2D6DBB022147" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_C319D2606939300AE70F2D6DBB025729" xlink:to="loc_endp_AstoraMember_D7B7EAD94E38A084148C2D6DBB022147" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems" xlink:label="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_6E92FB5973D1238A28F92D6DBB020889" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_61C0A2CA86A1A5D198B12D6DBB015009" xlink:to="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_6E92FB5973D1238A28F92D6DBB020889" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_DisposalGroupIncludingDiscontinuedOperationLitigationRelatedAndOtherContingencies" xlink:label="loc_endp_DisposalGroupIncludingDiscontinuedOperationLitigationRelatedAndOtherContingencies_36F7ED9402F6124F4BD62D6DBB0276B9" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_6E92FB5973D1238A28F92D6DBB020889" xlink:to="loc_endp_DisposalGroupIncludingDiscontinuedOperationLitigationRelatedAndOtherContingencies_36F7ED9402F6124F4BD62D6DBB0276B9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DiscontinuedOperationIncomeLossFromDiscontinuedOperationBeforeIncomeTax" xlink:label="loc_us-gaap_DiscontinuedOperationIncomeLossFromDiscontinuedOperationBeforeIncomeTax_2A056880DE495338431C2D6DBB0287F1" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_6E92FB5973D1238A28F92D6DBB020889" xlink:to="loc_us-gaap_DiscontinuedOperationIncomeLossFromDiscontinuedOperationBeforeIncomeTax_2A056880DE495338431C2D6DBB0287F1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DiscontinuedOperationTaxEffectOfDiscontinuedOperation" xlink:label="loc_us-gaap_DiscontinuedOperationTaxEffectOfDiscontinuedOperation_A911FE4B3F7053D5381B2D6DBB03EA54" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_6E92FB5973D1238A28F92D6DBB020889" xlink:to="loc_us-gaap_DiscontinuedOperationTaxEffectOfDiscontinuedOperation_A911FE4B3F7053D5381B2D6DBB03EA54" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxAttributableToReportingEntity" xlink:label="loc_us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxAttributableToReportingEntity_CABFC3AB3C5182EC0B912D6DBB031B4E" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_6E92FB5973D1238A28F92D6DBB020889" xlink:to="loc_us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxAttributableToReportingEntity_CABFC3AB3C5182EC0B912D6DBB031B4E" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/DiscontinuedOperationsAstoraNarrativeDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DiscontinuedOperationsAndDisposalGroupsAbstract" xlink:label="loc_us-gaap_DiscontinuedOperationsAndDisposalGroupsAbstract_6135FDD8956A5DC881B22F469533F1D6" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfRestructuringAndRelatedCostsTable" xlink:label="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_FDBCC19B5E1F5AE890CA99A57137861B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DiscontinuedOperationsAndDisposalGroupsAbstract_6135FDD8956A5DC881B22F469533F1D6" xlink:to="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_FDBCC19B5E1F5AE890CA99A57137861B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DisposalGroupClassificationAxis" xlink:label="loc_us-gaap_DisposalGroupClassificationAxis_1E3D990EEE525A20A49BBB993390D2FA" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_FDBCC19B5E1F5AE890CA99A57137861B" xlink:to="loc_us-gaap_DisposalGroupClassificationAxis_1E3D990EEE525A20A49BBB993390D2FA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DisposalGroupClassificationDomain" xlink:label="loc_us-gaap_DisposalGroupClassificationDomain_1E545E129556592C82A8A33F804D774D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisposalGroupClassificationAxis_1E3D990EEE525A20A49BBB993390D2FA" xlink:to="loc_us-gaap_DisposalGroupClassificationDomain_1E545E129556592C82A8A33F804D774D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DiscontinuedOperationsDisposedOfByMeansOtherThanSaleAbandonmentMember" xlink:label="loc_us-gaap_DiscontinuedOperationsDisposedOfByMeansOtherThanSaleAbandonmentMember_3D8890D3E2C25883A30F92E0692292A6" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisposalGroupClassificationDomain_1E545E129556592C82A8A33F804D774D" xlink:to="loc_us-gaap_DiscontinuedOperationsDisposedOfByMeansOtherThanSaleAbandonmentMember_3D8890D3E2C25883A30F92E0692292A6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis" xlink:label="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_154465D53D915A95A2B82A5DF77D704C" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_FDBCC19B5E1F5AE890CA99A57137861B" xlink:to="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_154465D53D915A95A2B82A5DF77D704C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain" xlink:label="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_891AA33E36BB5173AD28786E8E395147" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_154465D53D915A95A2B82A5DF77D704C" xlink:to="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_891AA33E36BB5173AD28786E8E395147" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_AstoraMember" xlink:label="loc_endp_AstoraMember_1202D0AEB9775F3CBA7E47E2B1891138" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_891AA33E36BB5173AD28786E8E395147" xlink:to="loc_endp_AstoraMember_1202D0AEB9775F3CBA7E47E2B1891138" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestructuringCostAndReserveLineItems" xlink:label="loc_us-gaap_RestructuringCostAndReserveLineItems_0351895E38095B2DB282F9B992A66F9E" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_FDBCC19B5E1F5AE890CA99A57137861B" xlink:to="loc_us-gaap_RestructuringCostAndReserveLineItems_0351895E38095B2DB282F9B992A66F9E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxAttributableToReportingEntity" xlink:label="loc_us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxAttributableToReportingEntity_1F88BC7094CD599B84CFECD687237DBD" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringCostAndReserveLineItems_0351895E38095B2DB282F9B992A66F9E" xlink:to="loc_us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxAttributableToReportingEntity_1F88BC7094CD599B84CFECD687237DBD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CashProvidedByUsedInInvestingActivitiesDiscontinuedOperations" xlink:label="loc_us-gaap_CashProvidedByUsedInInvestingActivitiesDiscontinuedOperations_FD6F4773521B5A96A431B021354AFF9F" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringCostAndReserveLineItems_0351895E38095B2DB282F9B992A66F9E" xlink:to="loc_us-gaap_CashProvidedByUsedInInvestingActivitiesDiscontinuedOperations_FD6F4773521B5A96A431B021354AFF9F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationDepreciationAndAmortization" xlink:label="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationDepreciationAndAmortization_CA6E92670A5B5029B1FE9799B1ABF2AA" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringCostAndReserveLineItems_0351895E38095B2DB282F9B992A66F9E" xlink:to="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationDepreciationAndAmortization_CA6E92670A5B5029B1FE9799B1ABF2AA" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/DiscontinuedOperationsTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DiscontinuedOperationsAndDisposalGroupsAbstract" xlink:label="loc_us-gaap_DiscontinuedOperationsAndDisposalGroupsAbstract_05A944C1B47A5187970E18F581027417" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfDisposalGroupsIncludingDiscontinuedOperationsIncomeStatementBalanceSheetAndAdditionalDisclosuresTextBlock" xlink:label="loc_us-gaap_ScheduleOfDisposalGroupsIncludingDiscontinuedOperationsIncomeStatementBalanceSheetAndAdditionalDisclosuresTextBlock_E4DCB766EDB05639A01AC94DB5E6166F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DiscontinuedOperationsAndDisposalGroupsAbstract_05A944C1B47A5187970E18F581027417" xlink:to="loc_us-gaap_ScheduleOfDisposalGroupsIncludingDiscontinuedOperationsIncomeStatementBalanceSheetAndAdditionalDisclosuresTextBlock_E4DCB766EDB05639A01AC94DB5E6166F" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/FairValueMeasurements" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueDisclosuresAbstract" xlink:label="loc_us-gaap_FairValueDisclosuresAbstract_10E6829E5B9A5C2D927BF739FDC10380" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueDisclosuresTextBlock" xlink:label="loc_us-gaap_FairValueDisclosuresTextBlock_2F5DA649EED559A9BDD1599DE2D30CE0" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_10E6829E5B9A5C2D927BF739FDC10380" xlink:to="loc_us-gaap_FairValueDisclosuresTextBlock_2F5DA649EED559A9BDD1599DE2D30CE0" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/FairValueMeasurementsFinancialAssetsAndLiabilitiesMeasuredAtFairValueOnRecurringBasisDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueDisclosuresAbstract" xlink:label="loc_us-gaap_FairValueDisclosuresAbstract_191513261247532DA463CC0226FCDCE4" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationTable" xlink:label="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationTable_2A0FF01E3DBC5FDB97068C312EA283DB" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_191513261247532DA463CC0226FCDCE4" xlink:to="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationTable_2A0FF01E3DBC5FDB97068C312EA283DB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueByMeasurementFrequencyAxis" xlink:label="loc_us-gaap_FairValueByMeasurementFrequencyAxis_494F1D131F3555ACA360EF0C1357379D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationTable_2A0FF01E3DBC5FDB97068C312EA283DB" xlink:to="loc_us-gaap_FairValueByMeasurementFrequencyAxis_494F1D131F3555ACA360EF0C1357379D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueMeasurementFrequencyDomain" xlink:label="loc_us-gaap_FairValueMeasurementFrequencyDomain_8A02687700EE59F0AACCB78A6629699C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueByMeasurementFrequencyAxis_494F1D131F3555ACA360EF0C1357379D" xlink:to="loc_us-gaap_FairValueMeasurementFrequencyDomain_8A02687700EE59F0AACCB78A6629699C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueMeasurementsRecurringMember" xlink:label="loc_us-gaap_FairValueMeasurementsRecurringMember_D25803954339518E8DF4037A80E9FCF8" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementFrequencyDomain_8A02687700EE59F0AACCB78A6629699C" xlink:to="loc_us-gaap_FairValueMeasurementsRecurringMember_D25803954339518E8DF4037A80E9FCF8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueByFairValueHierarchyLevelAxis" xlink:label="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_6EFB1AE240DB507FBA0EECFDEE2C4D1D" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationTable_2A0FF01E3DBC5FDB97068C312EA283DB" xlink:to="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_6EFB1AE240DB507FBA0EECFDEE2C4D1D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_35CBFF713603593BB6F53723CD11BD71" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_6EFB1AE240DB507FBA0EECFDEE2C4D1D" xlink:to="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_35CBFF713603593BB6F53723CD11BD71" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueInputsLevel1Member" xlink:label="loc_us-gaap_FairValueInputsLevel1Member_7320B4C3A2505E0EA6BC0F872FDFC960" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_35CBFF713603593BB6F53723CD11BD71" xlink:to="loc_us-gaap_FairValueInputsLevel1Member_7320B4C3A2505E0EA6BC0F872FDFC960" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueInputsLevel2Member" xlink:label="loc_us-gaap_FairValueInputsLevel2Member_C5293E770FAB54A7BBA831C273AB032E" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_35CBFF713603593BB6F53723CD11BD71" xlink:to="loc_us-gaap_FairValueInputsLevel2Member_C5293E770FAB54A7BBA831C273AB032E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueInputsLevel3Member" xlink:label="loc_us-gaap_FairValueInputsLevel3Member_6AC27DAF0F065B4FB6F988156A57C1F2" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_35CBFF713603593BB6F53723CD11BD71" xlink:to="loc_us-gaap_FairValueInputsLevel3Member_6AC27DAF0F065B4FB6F988156A57C1F2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FinancialInstrumentAxis" xlink:label="loc_us-gaap_FinancialInstrumentAxis_C297F1803F78505B913071E2EB03EAE5" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationTable_2A0FF01E3DBC5FDB97068C312EA283DB" xlink:to="loc_us-gaap_FinancialInstrumentAxis_C297F1803F78505B913071E2EB03EAE5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain" xlink:label="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_1685DAD0634A55209C0FE6BD8676210E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancialInstrumentAxis_C297F1803F78505B913071E2EB03EAE5" xlink:to="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_1685DAD0634A55209C0FE6BD8676210E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_MoneyMarketFundsMember" xlink:label="loc_us-gaap_MoneyMarketFundsMember_C7288F3509AE54D4802EE4D54C564F77" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_1685DAD0634A55209C0FE6BD8676210E" xlink:to="loc_us-gaap_MoneyMarketFundsMember_C7288F3509AE54D4802EE4D54C564F77" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ContingentConsiderationByTypeAxis" xlink:label="loc_us-gaap_ContingentConsiderationByTypeAxis_5C6FF7F6E81159E7B883E1F72638517D" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationTable_2A0FF01E3DBC5FDB97068C312EA283DB" xlink:to="loc_us-gaap_ContingentConsiderationByTypeAxis_5C6FF7F6E81159E7B883E1F72638517D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ContingentConsiderationTypeDomain" xlink:label="loc_us-gaap_ContingentConsiderationTypeDomain_02CAAFA6733A563991068CE1F0A2C5FD" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ContingentConsiderationByTypeAxis_5C6FF7F6E81159E7B883E1F72638517D" xlink:to="loc_us-gaap_ContingentConsiderationTypeDomain_02CAAFA6733A563991068CE1F0A2C5FD" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_AcquisitionRelatedContingentConsiderationShortTermMember" xlink:label="loc_endp_AcquisitionRelatedContingentConsiderationShortTermMember_2B3807C948F7560982281387FAD57324" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ContingentConsiderationTypeDomain_02CAAFA6733A563991068CE1F0A2C5FD" xlink:to="loc_endp_AcquisitionRelatedContingentConsiderationShortTermMember_2B3807C948F7560982281387FAD57324" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_AcquisitionRelatedContingentConsiderationLongTermMember" xlink:label="loc_endp_AcquisitionRelatedContingentConsiderationLongTermMember_03232FCA410559E8A0BFA8AE7C47D4DA" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ContingentConsiderationTypeDomain_02CAAFA6733A563991068CE1F0A2C5FD" xlink:to="loc_endp_AcquisitionRelatedContingentConsiderationLongTermMember_03232FCA410559E8A0BFA8AE7C47D4DA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationLineItems" xlink:label="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationLineItems_4E50A11F90C85473BA1E79C3F7D01C94" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationTable_2A0FF01E3DBC5FDB97068C312EA283DB" xlink:to="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationLineItems_4E50A11F90C85473BA1E79C3F7D01C94" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AssetsAbstract" xlink:label="loc_us-gaap_AssetsAbstract_59354F580E775B26B7CDDE59C4281949" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationLineItems_4E50A11F90C85473BA1E79C3F7D01C94" xlink:to="loc_us-gaap_AssetsAbstract_59354F580E775B26B7CDDE59C4281949" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AssetsFairValueDisclosure" xlink:label="loc_us-gaap_AssetsFairValueDisclosure_9182BD3C0B3A527E90AB167ECECFE17B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_59354F580E775B26B7CDDE59C4281949" xlink:to="loc_us-gaap_AssetsFairValueDisclosure_9182BD3C0B3A527E90AB167ECECFE17B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LiabilitiesAbstract" xlink:label="loc_us-gaap_LiabilitiesAbstract_D94C28ED0AF25D169B9BEC84B318ACD5" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationLineItems_4E50A11F90C85473BA1E79C3F7D01C94" xlink:to="loc_us-gaap_LiabilitiesAbstract_D94C28ED0AF25D169B9BEC84B318ACD5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LiabilitiesFairValueDisclosure" xlink:label="loc_us-gaap_LiabilitiesFairValueDisclosure_A5C9AA77AEAE5C25BA608ACF294595E0" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAbstract_D94C28ED0AF25D169B9BEC84B318ACD5" xlink:to="loc_us-gaap_LiabilitiesFairValueDisclosure_A5C9AA77AEAE5C25BA608ACF294595E0" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/FairValueMeasurementsFinancialLiabilitiesMeasuredAtFairValueOnRecurringBasisUsingSignificantUnobservableInputsDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueDisclosuresAbstract" xlink:label="loc_us-gaap_FairValueDisclosuresAbstract_32CEB2FFE1FD50829CA9ADAC1184181B" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationTable" xlink:label="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationTable_17927EAED80456A5B8795A5D67D66031" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_32CEB2FFE1FD50829CA9ADAC1184181B" xlink:to="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationTable_17927EAED80456A5B8795A5D67D66031" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ContingentConsiderationByTypeAxis" xlink:label="loc_us-gaap_ContingentConsiderationByTypeAxis_50B605DE94EE52F4BFCCE99A7F4430B7" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationTable_17927EAED80456A5B8795A5D67D66031" xlink:to="loc_us-gaap_ContingentConsiderationByTypeAxis_50B605DE94EE52F4BFCCE99A7F4430B7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ContingentConsiderationTypeDomain" xlink:label="loc_us-gaap_ContingentConsiderationTypeDomain_AF6FBD01A5B55D25BB897F3B2B8133F7" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ContingentConsiderationByTypeAxis_50B605DE94EE52F4BFCCE99A7F4430B7" xlink:to="loc_us-gaap_ContingentConsiderationTypeDomain_AF6FBD01A5B55D25BB897F3B2B8133F7" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_AcquisitionRelatedContingentConsiderationMember" xlink:label="loc_endp_AcquisitionRelatedContingentConsiderationMember_1A3A26831CBC599C88E8FCF389452F2D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ContingentConsiderationTypeDomain_AF6FBD01A5B55D25BB897F3B2B8133F7" xlink:to="loc_endp_AcquisitionRelatedContingentConsiderationMember_1A3A26831CBC599C88E8FCF389452F2D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessAcquisitionAxis" xlink:label="loc_us-gaap_BusinessAcquisitionAxis_DB0C2647DE925926BD427C740A716BD8" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationTable_17927EAED80456A5B8795A5D67D66031" xlink:to="loc_us-gaap_BusinessAcquisitionAxis_DB0C2647DE925926BD427C740A716BD8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_D1376EF945D853E6A475C182340B307E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_DB0C2647DE925926BD427C740A716BD8" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_D1376EF945D853E6A475C182340B307E" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_AuxiliumPharmaceuticalsInc.Member" xlink:label="loc_endp_AuxiliumPharmaceuticalsInc.Member_B693F221A5515627AE4D85712D526C11" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_D1376EF945D853E6A475C182340B307E" xlink:to="loc_endp_AuxiliumPharmaceuticalsInc.Member_B693F221A5515627AE4D85712D526C11" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_LehighValleyTechnologiesInc.Member" xlink:label="loc_endp_LehighValleyTechnologiesInc.Member_EAAD2014670D54C7B62FD196948A2F60" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_D1376EF945D853E6A475C182340B307E" xlink:to="loc_endp_LehighValleyTechnologiesInc.Member_EAAD2014670D54C7B62FD196948A2F60" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_VoltarenGelMember" xlink:label="loc_endp_VoltarenGelMember_51276E8353145ED2859EE175A514C68E" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_D1376EF945D853E6A475C182340B307E" xlink:to="loc_endp_VoltarenGelMember_51276E8353145ED2859EE175A514C68E" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_OtherAcquisitionsMember" xlink:label="loc_endp_OtherAcquisitionsMember_61850BFAF57E520290A7F1567A50D94E" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_D1376EF945D853E6A475C182340B307E" xlink:to="loc_endp_OtherAcquisitionsMember_61850BFAF57E520290A7F1567A50D94E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationLineItems" xlink:label="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationLineItems_C088D58358B55B77BE08507DB3095FFC" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationTable_17927EAED80456A5B8795A5D67D66031" xlink:to="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationLineItems_C088D58358B55B77BE08507DB3095FFC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward" xlink:label="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_525ADDE0EEA45663820EB355910A5B99" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationLineItems_C088D58358B55B77BE08507DB3095FFC" xlink:to="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_525ADDE0EEA45663820EB355910A5B99" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue" xlink:label="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue_3A43096FC84C500CA8FE90496AE638B8" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_525ADDE0EEA45663820EB355910A5B99" xlink:to="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue_3A43096FC84C500CA8FE90496AE638B8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilitySettlements" xlink:label="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilitySettlements_8D2D565DDC505FDE8AF73D3CDE07B9D6" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_525ADDE0EEA45663820EB355910A5B99" xlink:to="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilitySettlements_8D2D565DDC505FDE8AF73D3CDE07B9D6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityGainLossIncludedInEarnings" xlink:label="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityGainLossIncludedInEarnings_8CEF5E8E03065EA688E7FEAEA316297A" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_525ADDE0EEA45663820EB355910A5B99" xlink:to="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityGainLossIncludedInEarnings_8CEF5E8E03065EA688E7FEAEA316297A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityGainLossIncludedInOtherComprehensiveIncome" xlink:label="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityGainLossIncludedInOtherComprehensiveIncome_5E400EF8799E56748670D0D81B49AD2A" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_525ADDE0EEA45663820EB355910A5B99" xlink:to="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityGainLossIncludedInOtherComprehensiveIncome_5E400EF8799E56748670D0D81B49AD2A" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_FairValueMeasurementwithUnobservableInputsReconciliationRecurringBasisLiabilityAdjustmentsAndAccretion" xlink:label="loc_endp_FairValueMeasurementwithUnobservableInputsReconciliationRecurringBasisLiabilityAdjustmentsAndAccretion_CE719652FC605E039B3AF6753B39DEEE" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_525ADDE0EEA45663820EB355910A5B99" xlink:to="loc_endp_FairValueMeasurementwithUnobservableInputsReconciliationRecurringBasisLiabilityAdjustmentsAndAccretion_CE719652FC605E039B3AF6753B39DEEE" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilitySettlementsAndEffectOfCurrencyTranslation" xlink:label="loc_endp_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilitySettlementsAndEffectOfCurrencyTranslation_01241BC191BB522E8612D3A8A5EB612A" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_525ADDE0EEA45663820EB355910A5B99" xlink:to="loc_endp_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilitySettlementsAndEffectOfCurrencyTranslation_01241BC191BB522E8612D3A8A5EB612A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue" xlink:label="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue_683EAC91B5575EF5ABD7174FA0B41A4F" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_525ADDE0EEA45663820EB355910A5B99" xlink:to="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue_683EAC91B5575EF5ABD7174FA0B41A4F" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/FairValueMeasurementsNarrativeDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueDisclosuresAbstract" xlink:label="loc_us-gaap_FairValueDisclosuresAbstract_3F432A4F94A2575BA0C3D6DF8BAD622F" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationTable" xlink:label="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationTable_CC820846EB0159C1893EFABF25628E69" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_3F432A4F94A2575BA0C3D6DF8BAD622F" xlink:to="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationTable_CC820846EB0159C1893EFABF25628E69" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_MeasurementInputTypeAxis" xlink:label="loc_us-gaap_MeasurementInputTypeAxis_758C9787434859489556F440D52F8265" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationTable_CC820846EB0159C1893EFABF25628E69" xlink:to="loc_us-gaap_MeasurementInputTypeAxis_758C9787434859489556F440D52F8265" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_MeasurementInputTypeDomain" xlink:label="loc_us-gaap_MeasurementInputTypeDomain_FEAF0BA2337D5E3B8757FBBC90F0FE27" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MeasurementInputTypeAxis_758C9787434859489556F440D52F8265" xlink:to="loc_us-gaap_MeasurementInputTypeDomain_FEAF0BA2337D5E3B8757FBBC90F0FE27" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_MeasurementInputDiscountRateMember" xlink:label="loc_us-gaap_MeasurementInputDiscountRateMember_7A2AA9EBB2775288BBB1DA8D0629DF70" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MeasurementInputTypeDomain_FEAF0BA2337D5E3B8757FBBC90F0FE27" xlink:to="loc_us-gaap_MeasurementInputDiscountRateMember_7A2AA9EBB2775288BBB1DA8D0629DF70" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FinancialInstrumentAxis" xlink:label="loc_us-gaap_FinancialInstrumentAxis_5E7EDCF62F6E5134B8328EE0B2E7E84D" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationTable_CC820846EB0159C1893EFABF25628E69" xlink:to="loc_us-gaap_FinancialInstrumentAxis_5E7EDCF62F6E5134B8328EE0B2E7E84D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain" xlink:label="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_AF9406A4B5A3556BA6F6E534F72D5F8D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancialInstrumentAxis_5E7EDCF62F6E5134B8328EE0B2E7E84D" xlink:to="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_AF9406A4B5A3556BA6F6E534F72D5F8D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_MoneyMarketFundsMember" xlink:label="loc_us-gaap_MoneyMarketFundsMember_EA4EBE87225B5645816F2677DBC57703" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_AF9406A4B5A3556BA6F6E534F72D5F8D" xlink:to="loc_us-gaap_MoneyMarketFundsMember_EA4EBE87225B5645816F2677DBC57703" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_InvestmentTypeAxis" xlink:label="loc_us-gaap_InvestmentTypeAxis_A1504CD0B829581688EE56FEB8B4579A" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationTable_CC820846EB0159C1893EFABF25628E69" xlink:to="loc_us-gaap_InvestmentTypeAxis_A1504CD0B829581688EE56FEB8B4579A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_InvestmentTypeCategorizationMember" xlink:label="loc_us-gaap_InvestmentTypeCategorizationMember_A0EA956D56BA57369FBC944405C821D6" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InvestmentTypeAxis_A1504CD0B829581688EE56FEB8B4579A" xlink:to="loc_us-gaap_InvestmentTypeCategorizationMember_A0EA956D56BA57369FBC944405C821D6" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_RestrictedCashAndCashEquivalentsMember" xlink:label="loc_endp_RestrictedCashAndCashEquivalentsMember_43AE36B4C95255189C33BB205CB4FF92" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InvestmentTypeCategorizationMember_A0EA956D56BA57369FBC944405C821D6" xlink:to="loc_endp_RestrictedCashAndCashEquivalentsMember_43AE36B4C95255189C33BB205CB4FF92" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_RangeAxis" xlink:label="loc_srt_RangeAxis_2E4822A7EB945B1C857871E0A8BE4119" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationTable_CC820846EB0159C1893EFABF25628E69" xlink:to="loc_srt_RangeAxis_2E4822A7EB945B1C857871E0A8BE4119" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_RangeMember" xlink:label="loc_srt_RangeMember_1E6BACD7B196587C91578DF783EE154B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeAxis_2E4822A7EB945B1C857871E0A8BE4119" xlink:to="loc_srt_RangeMember_1E6BACD7B196587C91578DF783EE154B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_MinimumMember" xlink:label="loc_srt_MinimumMember_DB3EF23C34B051F589DE6AAD61292BE2" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_1E6BACD7B196587C91578DF783EE154B" xlink:to="loc_srt_MinimumMember_DB3EF23C34B051F589DE6AAD61292BE2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_MaximumMember" xlink:label="loc_srt_MaximumMember_0B5953C8130E564C8DBCF38682543B74" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_1E6BACD7B196587C91578DF783EE154B" xlink:to="loc_srt_MaximumMember_0B5953C8130E564C8DBCF38682543B74" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_WeightedAverageMember" xlink:label="loc_srt_WeightedAverageMember_F177FD8758FC59728AA314780A0FEE55" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_1E6BACD7B196587C91578DF783EE154B" xlink:to="loc_srt_WeightedAverageMember_F177FD8758FC59728AA314780A0FEE55" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationLineItems" xlink:label="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationLineItems_32E045B892BB51F6B9FD8019DF443BAD" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationTable_CC820846EB0159C1893EFABF25628E69" xlink:to="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationLineItems_32E045B892BB51F6B9FD8019DF443BAD" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_SettlementFunds" xlink:label="loc_endp_SettlementFunds_31B235D703A15DE69C5AA25F84E25F30" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationLineItems_32E045B892BB51F6B9FD8019DF443BAD" xlink:to="loc_endp_SettlementFunds_31B235D703A15DE69C5AA25F84E25F30" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationLiabilityMeasurementInput" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationLiabilityMeasurementInput_0079B3527AA75959851E215C365FD542" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationLineItems_32E045B892BB51F6B9FD8019DF443BAD" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationLiabilityMeasurementInput_0079B3527AA75959851E215C365FD542" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_GoodwillImpairmentLoss" xlink:label="loc_us-gaap_GoodwillImpairmentLoss_996F0006BFED52CEB40D4E7553136E3F" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationLineItems_32E045B892BB51F6B9FD8019DF443BAD" xlink:to="loc_us-gaap_GoodwillImpairmentLoss_996F0006BFED52CEB40D4E7553136E3F" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/FairValueMeasurementsRestrictedCashAndCashEquivalentsDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueDisclosuresAbstract" xlink:label="loc_us-gaap_FairValueDisclosuresAbstract_652170F1A0365D0F9FF199E08C23F4BD" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfRestrictedCashAndCashEquivalentsTable" xlink:label="loc_us-gaap_ScheduleOfRestrictedCashAndCashEquivalentsTable_3F93956169115BD1B8F3AB92E63E2982" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_652170F1A0365D0F9FF199E08C23F4BD" xlink:to="loc_us-gaap_ScheduleOfRestrictedCashAndCashEquivalentsTable_3F93956169115BD1B8F3AB92E63E2982" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_LitigationCaseAxis" xlink:label="loc_srt_LitigationCaseAxis_64BAC477057558DF9755890A83B12F3D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRestrictedCashAndCashEquivalentsTable_3F93956169115BD1B8F3AB92E63E2982" xlink:to="loc_srt_LitigationCaseAxis_64BAC477057558DF9755890A83B12F3D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_LitigationCaseTypeDomain" xlink:label="loc_srt_LitigationCaseTypeDomain_DE62654A6B0D5952876AD5FB88B166FD" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_LitigationCaseAxis_64BAC477057558DF9755890A83B12F3D" xlink:to="loc_srt_LitigationCaseTypeDomain_DE62654A6B0D5952876AD5FB88B166FD" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_VaginalMeshCasesMember" xlink:label="loc_endp_VaginalMeshCasesMember_051744D2DB8A54F0AB8B3CAFCAC4A800" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_LitigationCaseTypeDomain_DE62654A6B0D5952876AD5FB88B166FD" xlink:to="loc_endp_VaginalMeshCasesMember_051744D2DB8A54F0AB8B3CAFCAC4A800" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestrictedCashAndCashEquivalentsItemsLineItems" xlink:label="loc_us-gaap_RestrictedCashAndCashEquivalentsItemsLineItems_A4501FC3EBCE52248B79C5416BDC1F28" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRestrictedCashAndCashEquivalentsTable_3F93956169115BD1B8F3AB92E63E2982" xlink:to="loc_us-gaap_RestrictedCashAndCashEquivalentsItemsLineItems_A4501FC3EBCE52248B79C5416BDC1F28" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestrictedCashAndCashEquivalentsAtCarryingValue" xlink:label="loc_us-gaap_RestrictedCashAndCashEquivalentsAtCarryingValue_856F41BE9CFC5FA0A9356E804E0B298A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestrictedCashAndCashEquivalentsItemsLineItems_A4501FC3EBCE52248B79C5416BDC1F28" xlink:to="loc_us-gaap_RestrictedCashAndCashEquivalentsAtCarryingValue_856F41BE9CFC5FA0A9356E804E0B298A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestrictedCashAndCashEquivalentsNoncurrent" xlink:label="loc_us-gaap_RestrictedCashAndCashEquivalentsNoncurrent_BB4033490F805746BCDD672C98F9629C" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestrictedCashAndCashEquivalentsItemsLineItems_A4501FC3EBCE52248B79C5416BDC1F28" xlink:to="loc_us-gaap_RestrictedCashAndCashEquivalentsNoncurrent_BB4033490F805746BCDD672C98F9629C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestrictedCashAndCashEquivalents" xlink:label="loc_us-gaap_RestrictedCashAndCashEquivalents_8AB52B5DD8DA5107AD337B32FCA622E6" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestrictedCashAndCashEquivalentsItemsLineItems_A4501FC3EBCE52248B79C5416BDC1F28" xlink:to="loc_us-gaap_RestrictedCashAndCashEquivalents_8AB52B5DD8DA5107AD337B32FCA622E6" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_SettlementFunds" xlink:label="loc_endp_SettlementFunds_9DFA6606A9D55451BBC9013CDA1C611E" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestrictedCashAndCashEquivalentsItemsLineItems_A4501FC3EBCE52248B79C5416BDC1F28" xlink:to="loc_endp_SettlementFunds_9DFA6606A9D55451BBC9013CDA1C611E" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/FairValueMeasurementsScheduleOfFinancialAssetsMeasuredAtFairValueOnNonrecurringBasisDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueDisclosuresAbstract" xlink:label="loc_us-gaap_FairValueDisclosuresAbstract_4E2B3DC5981A531DB75FCB3BC7E6C4D9" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_5F9F00A963715558BBA6CB6242418F1D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_4E2B3DC5981A531DB75FCB3BC7E6C4D9" xlink:to="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_5F9F00A963715558BBA6CB6242418F1D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueByFairValueHierarchyLevelAxis" xlink:label="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_AFCC0463ABEE51BD853FA62CAB4C97EA" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_5F9F00A963715558BBA6CB6242418F1D" xlink:to="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_AFCC0463ABEE51BD853FA62CAB4C97EA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_1AB39B9B8905540AAA3A49025F4A2E1E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_AFCC0463ABEE51BD853FA62CAB4C97EA" xlink:to="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_1AB39B9B8905540AAA3A49025F4A2E1E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueInputsLevel1Member" xlink:label="loc_us-gaap_FairValueInputsLevel1Member_24638608A5055EAABB86C6FED4C137BE" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_1AB39B9B8905540AAA3A49025F4A2E1E" xlink:to="loc_us-gaap_FairValueInputsLevel1Member_24638608A5055EAABB86C6FED4C137BE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueInputsLevel2Member" xlink:label="loc_us-gaap_FairValueInputsLevel2Member_023BE0E480B0597DA1B43904AB651ED7" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_1AB39B9B8905540AAA3A49025F4A2E1E" xlink:to="loc_us-gaap_FairValueInputsLevel2Member_023BE0E480B0597DA1B43904AB651ED7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueInputsLevel3Member" xlink:label="loc_us-gaap_FairValueInputsLevel3Member_D33AF89AD6E25FB6A16DBF60D2A8C222" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_1AB39B9B8905540AAA3A49025F4A2E1E" xlink:to="loc_us-gaap_FairValueInputsLevel3Member_D33AF89AD6E25FB6A16DBF60D2A8C222" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueByMeasurementFrequencyAxis" xlink:label="loc_us-gaap_FairValueByMeasurementFrequencyAxis_C13B6661E5D359DB8B8DABC0F723E3FC" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_5F9F00A963715558BBA6CB6242418F1D" xlink:to="loc_us-gaap_FairValueByMeasurementFrequencyAxis_C13B6661E5D359DB8B8DABC0F723E3FC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueMeasurementFrequencyDomain" xlink:label="loc_us-gaap_FairValueMeasurementFrequencyDomain_8512B0B268E153FEA4D4790A6B999F4C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueByMeasurementFrequencyAxis_C13B6661E5D359DB8B8DABC0F723E3FC" xlink:to="loc_us-gaap_FairValueMeasurementFrequencyDomain_8512B0B268E153FEA4D4790A6B999F4C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueMeasurementsNonrecurringMember" xlink:label="loc_us-gaap_FairValueMeasurementsNonrecurringMember_75BF5829A5595AC687D93207770FD71C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementFrequencyDomain_8512B0B268E153FEA4D4790A6B999F4C" xlink:to="loc_us-gaap_FairValueMeasurementsNonrecurringMember_75BF5829A5595AC687D93207770FD71C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueByAssetClassAxis" xlink:label="loc_us-gaap_FairValueByAssetClassAxis_0064DD6D238F5D588BDB1CB1D3E8BF0B" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_5F9F00A963715558BBA6CB6242418F1D" xlink:to="loc_us-gaap_FairValueByAssetClassAxis_0064DD6D238F5D588BDB1CB1D3E8BF0B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationByAssetClassDomain" xlink:label="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationByAssetClassDomain_B2B4658CD9A65555947C6305CD7F5D99" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueByAssetClassAxis_0064DD6D238F5D588BDB1CB1D3E8BF0B" xlink:to="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationByAssetClassDomain_B2B4658CD9A65555947C6305CD7F5D99" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_IntangibleAssetsMember" xlink:label="loc_endp_IntangibleAssetsMember_CA572B709DCE50EA946A7B519FD86667" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationByAssetClassDomain_B2B4658CD9A65555947C6305CD7F5D99" xlink:to="loc_endp_IntangibleAssetsMember_CA572B709DCE50EA946A7B519FD86667" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_PropertyPlantAndEquipmentMember" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentMember_3D2A218E8FCA5825A9C68D8393E652B5" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationByAssetClassDomain_B2B4658CD9A65555947C6305CD7F5D99" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentMember_3D2A218E8FCA5825A9C68D8393E652B5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_17BFD0D7F25B5E4592E125BD6FB94C79" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_5F9F00A963715558BBA6CB6242418F1D" xlink:to="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_17BFD0D7F25B5E4592E125BD6FB94C79" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AssetsFairValueDisclosureAbstract" xlink:label="loc_us-gaap_AssetsFairValueDisclosureAbstract_0C5A77BB16FD5D699FCEC3C094B1192E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_17BFD0D7F25B5E4592E125BD6FB94C79" xlink:to="loc_us-gaap_AssetsFairValueDisclosureAbstract_0C5A77BB16FD5D699FCEC3C094B1192E" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_IntangibleAssetsExcludingGoodwillFairValueDisclosure" xlink:label="loc_endp_IntangibleAssetsExcludingGoodwillFairValueDisclosure_0790881099DD5A378EE5332D9A062AF0" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsFairValueDisclosureAbstract_0C5A77BB16FD5D699FCEC3C094B1192E" xlink:to="loc_endp_IntangibleAssetsExcludingGoodwillFairValueDisclosure_0790881099DD5A378EE5332D9A062AF0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_PropertyPlantAndEquipmentFairValueDisclosure" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentFairValueDisclosure_67ED20429256586999ABC90454791705" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsFairValueDisclosureAbstract_0C5A77BB16FD5D699FCEC3C094B1192E" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentFairValueDisclosure_67ED20429256586999ABC90454791705" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AssetsFairValueDisclosure" xlink:label="loc_us-gaap_AssetsFairValueDisclosure_8643F91B85A65AE1AD5F210AF15B25AE" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsFairValueDisclosureAbstract_0C5A77BB16FD5D699FCEC3C094B1192E" xlink:to="loc_us-gaap_AssetsFairValueDisclosure_8643F91B85A65AE1AD5F210AF15B25AE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AssetImpairmentCharges" xlink:label="loc_us-gaap_AssetImpairmentCharges_E7ECC756807052D692EDD477B0175C97" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsFairValueDisclosureAbstract_0C5A77BB16FD5D699FCEC3C094B1192E" xlink:to="loc_us-gaap_AssetImpairmentCharges_E7ECC756807052D692EDD477B0175C97" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/FairValueMeasurementsTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueDisclosuresAbstract" xlink:label="loc_us-gaap_FairValueDisclosuresAbstract_6DB106E7A77859FFA868DD9F2563545B" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfCashAndCashEquivalentsTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfCashAndCashEquivalentsTableTextBlock_B0C5473344715545AA4A7F88180402EB" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_6DB106E7A77859FFA868DD9F2563545B" xlink:to="loc_us-gaap_ScheduleOfCashAndCashEquivalentsTableTextBlock_B0C5473344715545AA4A7F88180402EB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfRestrictedCashAndCashEquivalentsTextBlock" xlink:label="loc_us-gaap_ScheduleOfRestrictedCashAndCashEquivalentsTextBlock_8ADF9F5F722554CFAB1ACC733C9553EC" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_6DB106E7A77859FFA868DD9F2563545B" xlink:to="loc_us-gaap_ScheduleOfRestrictedCashAndCashEquivalentsTextBlock_8ADF9F5F722554CFAB1ACC733C9553EC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock_8D776ABBF7C6598C88B3930F2EE8EE5A" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_6DB106E7A77859FFA868DD9F2563545B" xlink:to="loc_us-gaap_ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock_8D776ABBF7C6598C88B3930F2EE8EE5A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationTextBlock" xlink:label="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationTextBlock_7D572D5C4B5556D3A286ABAC0331E0B2" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_6DB106E7A77859FFA868DD9F2563545B" xlink:to="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationTextBlock_7D572D5C4B5556D3A286ABAC0331E0B2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueAssetsMeasuredOnNonrecurringBasisTextBlock" xlink:label="loc_us-gaap_FairValueAssetsMeasuredOnNonrecurringBasisTextBlock_5BB0BE7469AC55A1A4CD8CBC7FDF07BA" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_6DB106E7A77859FFA868DD9F2563545B" xlink:to="loc_us-gaap_FairValueAssetsMeasuredOnNonrecurringBasisTextBlock_5BB0BE7469AC55A1A4CD8CBC7FDF07BA" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/GoodwillAndOtherIntangibles" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract" xlink:label="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_9B39D6B76F8556989BF2F63461438E69" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_GoodwillAndIntangibleAssetsDisclosureTextBlock" xlink:label="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureTextBlock_607ADBC9162355D1A1C42E564484633C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_9B39D6B76F8556989BF2F63461438E69" xlink:to="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureTextBlock_607ADBC9162355D1A1C42E564484633C" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/GoodwillAndOtherIntangiblesAccumulatedImpairmentDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract" xlink:label="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_937346BA9F635234961EDDFEB3245543" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfGoodwillTable" xlink:label="loc_us-gaap_ScheduleOfGoodwillTable_E34EA46AEA025FF68B2189FD22EB2855" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_937346BA9F635234961EDDFEB3245543" xlink:to="loc_us-gaap_ScheduleOfGoodwillTable_E34EA46AEA025FF68B2189FD22EB2855" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StatementBusinessSegmentsAxis" xlink:label="loc_us-gaap_StatementBusinessSegmentsAxis_506788B7C6DB5E4A9B5908834B5A9E40" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfGoodwillTable_E34EA46AEA025FF68B2189FD22EB2855" xlink:to="loc_us-gaap_StatementBusinessSegmentsAxis_506788B7C6DB5E4A9B5908834B5A9E40" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SegmentDomain" xlink:label="loc_us-gaap_SegmentDomain_A0E91F279C605015BD8F76D7B48B5895" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_506788B7C6DB5E4A9B5908834B5A9E40" xlink:to="loc_us-gaap_SegmentDomain_A0E91F279C605015BD8F76D7B48B5895" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_BrandedSpecialtyandEstablishedPharmaceuticalsMember" xlink:label="loc_endp_BrandedSpecialtyandEstablishedPharmaceuticalsMember_6C6047D6FD5355F5AFE49E606EBD5BB1" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_A0E91F279C605015BD8F76D7B48B5895" xlink:to="loc_endp_BrandedSpecialtyandEstablishedPharmaceuticalsMember_6C6047D6FD5355F5AFE49E606EBD5BB1" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_BrandedSterileInjectablesMember" xlink:label="loc_endp_BrandedSterileInjectablesMember_3C7F65EF55C357AB86D98AE45D045014" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_A0E91F279C605015BD8F76D7B48B5895" xlink:to="loc_endp_BrandedSterileInjectablesMember_3C7F65EF55C357AB86D98AE45D045014" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_GenericPharmaceuticalsMember" xlink:label="loc_endp_GenericPharmaceuticalsMember_D58ED641441052139E0218DC4D6974F7" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_A0E91F279C605015BD8F76D7B48B5895" xlink:to="loc_endp_GenericPharmaceuticalsMember_D58ED641441052139E0218DC4D6974F7" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_InternationalPharmaceuticalsMember" xlink:label="loc_endp_InternationalPharmaceuticalsMember_1B9BFC6FAB2754BDBDEF6915F5500911" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_A0E91F279C605015BD8F76D7B48B5895" xlink:to="loc_endp_InternationalPharmaceuticalsMember_1B9BFC6FAB2754BDBDEF6915F5500911" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_GoodwillLineItems" xlink:label="loc_us-gaap_GoodwillLineItems_15FB6EDAB86C5082B9F9759632FF6F5F" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfGoodwillTable_E34EA46AEA025FF68B2189FD22EB2855" xlink:to="loc_us-gaap_GoodwillLineItems_15FB6EDAB86C5082B9F9759632FF6F5F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_GoodwillImpairedAccumulatedImpairmentLoss" xlink:label="loc_us-gaap_GoodwillImpairedAccumulatedImpairmentLoss_85E011D4199B50388D7B1414F2DCC371" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillLineItems_15FB6EDAB86C5082B9F9759632FF6F5F" xlink:to="loc_us-gaap_GoodwillImpairedAccumulatedImpairmentLoss_85E011D4199B50388D7B1414F2DCC371" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/GoodwillAndOtherIntangiblesImpairmentsNarrativeDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract" xlink:label="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_58B10CDA74D65E9DB37D60F837BD43EA" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfGoodwillTable" xlink:label="loc_us-gaap_ScheduleOfGoodwillTable_06F4453ECB2E5FE280E47084E3AE793D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_58B10CDA74D65E9DB37D60F837BD43EA" xlink:to="loc_us-gaap_ScheduleOfGoodwillTable_06F4453ECB2E5FE280E47084E3AE793D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ReportingUnitAxis" xlink:label="loc_us-gaap_ReportingUnitAxis_E7AE17F19A9257D683CF3D936964A572" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfGoodwillTable_06F4453ECB2E5FE280E47084E3AE793D" xlink:to="loc_us-gaap_ReportingUnitAxis_E7AE17F19A9257D683CF3D936964A572" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ReportingUnitDomain" xlink:label="loc_us-gaap_ReportingUnitDomain_B95543D8D529519480F06FA9BCB78C41" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReportingUnitAxis_E7AE17F19A9257D683CF3D936964A572" xlink:to="loc_us-gaap_ReportingUnitDomain_B95543D8D529519480F06FA9BCB78C41" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_GenericPharmaceuticalsMember" xlink:label="loc_endp_GenericPharmaceuticalsMember_472951EBFD1B56D588BF78E67530FF77" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReportingUnitDomain_B95543D8D529519480F06FA9BCB78C41" xlink:to="loc_endp_GenericPharmaceuticalsMember_472951EBFD1B56D588BF78E67530FF77" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_FormerU.S.GenericPharmaceuticalsMember" xlink:label="loc_endp_FormerU.S.GenericPharmaceuticalsMember_21DAEDD6D22C525C8C04F426866D9BE5" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReportingUnitDomain_B95543D8D529519480F06FA9BCB78C41" xlink:to="loc_endp_FormerU.S.GenericPharmaceuticalsMember_21DAEDD6D22C525C8C04F426866D9BE5" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_SterileInjectablesMember" xlink:label="loc_endp_SterileInjectablesMember_56E8E75437A651B88F4318C28373549F" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReportingUnitDomain_B95543D8D529519480F06FA9BCB78C41" xlink:to="loc_endp_SterileInjectablesMember_56E8E75437A651B88F4318C28373549F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_MeasurementInputTypeAxis" xlink:label="loc_us-gaap_MeasurementInputTypeAxis_728C0BB836565E5C814E3A088FF965AC" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfGoodwillTable_06F4453ECB2E5FE280E47084E3AE793D" xlink:to="loc_us-gaap_MeasurementInputTypeAxis_728C0BB836565E5C814E3A088FF965AC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_MeasurementInputTypeDomain" xlink:label="loc_us-gaap_MeasurementInputTypeDomain_E6E53E8876BA50D0AA7B1167D3DA23E0" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MeasurementInputTypeAxis_728C0BB836565E5C814E3A088FF965AC" xlink:to="loc_us-gaap_MeasurementInputTypeDomain_E6E53E8876BA50D0AA7B1167D3DA23E0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_MeasurementInputDiscountRateMember" xlink:label="loc_us-gaap_MeasurementInputDiscountRateMember_770394DB439F561A8B54C1A5924802EB" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MeasurementInputTypeDomain_E6E53E8876BA50D0AA7B1167D3DA23E0" xlink:to="loc_us-gaap_MeasurementInputDiscountRateMember_770394DB439F561A8B54C1A5924802EB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StatementBusinessSegmentsAxis" xlink:label="loc_us-gaap_StatementBusinessSegmentsAxis_01D45C6A4B7C567CB65FD8A40D416207" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfGoodwillTable_06F4453ECB2E5FE280E47084E3AE793D" xlink:to="loc_us-gaap_StatementBusinessSegmentsAxis_01D45C6A4B7C567CB65FD8A40D416207" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SegmentDomain" xlink:label="loc_us-gaap_SegmentDomain_828C482C51975E9E94181FFCE694767A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_01D45C6A4B7C567CB65FD8A40D416207" xlink:to="loc_us-gaap_SegmentDomain_828C482C51975E9E94181FFCE694767A" xlink:type="arc" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_828C482C51975E9E94181FFCE694767A" xlink:to="loc_endp_GenericPharmaceuticalsMember_472951EBFD1B56D588BF78E67530FF77" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_GoodwillLineItems" xlink:label="loc_us-gaap_GoodwillLineItems_FF78CD0878385922A6B85F4EDC8837CA" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfGoodwillTable_06F4453ECB2E5FE280E47084E3AE793D" xlink:to="loc_us-gaap_GoodwillLineItems_FF78CD0878385922A6B85F4EDC8837CA" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_IntangibleAssetsNetIncludingGoodwillMeasurementInput" xlink:label="loc_endp_IntangibleAssetsNetIncludingGoodwillMeasurementInput_7C6BAE472B9551B9A264701049B4FD2A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillLineItems_FF78CD0878385922A6B85F4EDC8837CA" xlink:to="loc_endp_IntangibleAssetsNetIncludingGoodwillMeasurementInput_7C6BAE472B9551B9A264701049B4FD2A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_GoodwillImpairmentLoss" xlink:label="loc_us-gaap_GoodwillImpairmentLoss_0A90C6486E205477B71DC46812A49974" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillLineItems_FF78CD0878385922A6B85F4EDC8837CA" xlink:to="loc_us-gaap_GoodwillImpairmentLoss_0A90C6486E205477B71DC46812A49974" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/GoodwillAndOtherIntangiblesOtherIntangiblesNarrativeDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract" xlink:label="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_73F406174934508B8F8CEB2ED9C74312" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AmortizationOfIntangibleAssets" xlink:label="loc_us-gaap_AmortizationOfIntangibleAssets_51BE35C7A9785796A8EB1CDF5088DFD8" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_73F406174934508B8F8CEB2ED9C74312" xlink:to="loc_us-gaap_AmortizationOfIntangibleAssets_51BE35C7A9785796A8EB1CDF5088DFD8" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/GoodwillAndOtherIntangiblesScheduleOfChangesInCarryingAmountOfGoodwillDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract" xlink:label="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_D5CEDBED0ADC56F89DF8783B0AC9F337" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable" xlink:label="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_B3265CD87465519D9701052DD89BF00A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_D5CEDBED0ADC56F89DF8783B0AC9F337" xlink:to="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_B3265CD87465519D9701052DD89BF00A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StatementBusinessSegmentsAxis" xlink:label="loc_us-gaap_StatementBusinessSegmentsAxis_08BFC6102456579989524E2D908708B2" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_B3265CD87465519D9701052DD89BF00A" xlink:to="loc_us-gaap_StatementBusinessSegmentsAxis_08BFC6102456579989524E2D908708B2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SegmentDomain" xlink:label="loc_us-gaap_SegmentDomain_3284E1C0FA23596A9FD8F131C00A0C1E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_08BFC6102456579989524E2D908708B2" xlink:to="loc_us-gaap_SegmentDomain_3284E1C0FA23596A9FD8F131C00A0C1E" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_BrandedSpecialtyandEstablishedPharmaceuticalsMember" xlink:label="loc_endp_BrandedSpecialtyandEstablishedPharmaceuticalsMember_055D5146712657CBAE631D4327FBEA39" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_3284E1C0FA23596A9FD8F131C00A0C1E" xlink:to="loc_endp_BrandedSpecialtyandEstablishedPharmaceuticalsMember_055D5146712657CBAE631D4327FBEA39" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_BrandedSterileInjectablesMember" xlink:label="loc_endp_BrandedSterileInjectablesMember_B35E83CF71005CF8B379FF0DD2059005" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_3284E1C0FA23596A9FD8F131C00A0C1E" xlink:to="loc_endp_BrandedSterileInjectablesMember_B35E83CF71005CF8B379FF0DD2059005" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_GenericPharmaceuticalsMember" xlink:label="loc_endp_GenericPharmaceuticalsMember_5A9A6008FC9B5053907AAB6B6C90CB7B" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_3284E1C0FA23596A9FD8F131C00A0C1E" xlink:to="loc_endp_GenericPharmaceuticalsMember_5A9A6008FC9B5053907AAB6B6C90CB7B" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_InternationalPharmaceuticalsMember" xlink:label="loc_endp_InternationalPharmaceuticalsMember_2517CBD01F965041A38A4C0CE9313D94" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_3284E1C0FA23596A9FD8F131C00A0C1E" xlink:to="loc_endp_InternationalPharmaceuticalsMember_2517CBD01F965041A38A4C0CE9313D94" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SegmentReportingInformationLineItems" xlink:label="loc_us-gaap_SegmentReportingInformationLineItems_20E8EB606B7655339755052332497CD6" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_B3265CD87465519D9701052DD89BF00A" xlink:to="loc_us-gaap_SegmentReportingInformationLineItems_20E8EB606B7655339755052332497CD6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_GoodwillRollForward" xlink:label="loc_us-gaap_GoodwillRollForward_07D44670FAE45D4190534428DE6C03A2" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_20E8EB606B7655339755052332497CD6" xlink:to="loc_us-gaap_GoodwillRollForward_07D44670FAE45D4190534428DE6C03A2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_Goodwill" xlink:label="loc_us-gaap_Goodwill_247B65265E2A59C58128A94DF24F720A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillRollForward_07D44670FAE45D4190534428DE6C03A2" xlink:to="loc_us-gaap_Goodwill_247B65265E2A59C58128A94DF24F720A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_GoodwillForeignCurrencyTranslationGainLoss" xlink:label="loc_us-gaap_GoodwillForeignCurrencyTranslationGainLoss_6E5B6B3C598356BF9FF7E455ACAC28D2" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillRollForward_07D44670FAE45D4190534428DE6C03A2" xlink:to="loc_us-gaap_GoodwillForeignCurrencyTranslationGainLoss_6E5B6B3C598356BF9FF7E455ACAC28D2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_GoodwillImpairmentLoss" xlink:label="loc_us-gaap_GoodwillImpairmentLoss_411EFABA105452438C33C6A648AEF380" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillRollForward_07D44670FAE45D4190534428DE6C03A2" xlink:to="loc_us-gaap_GoodwillImpairmentLoss_411EFABA105452438C33C6A648AEF380" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_Goodwill" xlink:label="loc_us-gaap_Goodwill_EEA8EF5201A558BDB134CF5A205C850B" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillRollForward_07D44670FAE45D4190534428DE6C03A2" xlink:to="loc_us-gaap_Goodwill_EEA8EF5201A558BDB134CF5A205C850B" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/GoodwillAndOtherIntangiblesScheduleOfEstimatedAmortizationOfIntangiblesDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract" xlink:label="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_7270727DC6DA46171F3468FC709CF41E" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_9A4135EB1C0789A53D5E68FFA62B1CAF" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_7270727DC6DA46171F3468FC709CF41E" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_9A4135EB1C0789A53D5E68FFA62B1CAF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_D8E4CBF96EB0DE648C1B68FC709D8B2D" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_7270727DC6DA46171F3468FC709CF41E" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_D8E4CBF96EB0DE648C1B68FC709D8B2D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_D14B3BC08174C1D57AFF68FC709D4CF8" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_7270727DC6DA46171F3468FC709CF41E" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_D14B3BC08174C1D57AFF68FC709D4CF8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_792C2A48B78D7C76AC2868FC709ED78C" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_7270727DC6DA46171F3468FC709CF41E" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_792C2A48B78D7C76AC2868FC709ED78C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive_0718AB49B2026E4A469068FC709EA86B" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_7270727DC6DA46171F3468FC709CF41E" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive_0718AB49B2026E4A469068FC709EA86B" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/GoodwillAndOtherIntangiblesScheduleOfIntangibleAssetImpairmentChargesIncludingGoodwillDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract" xlink:label="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_F9A6AFEF860651F2BEC8EE8B02CA2AA3" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_GoodwillImpairmentLoss" xlink:label="loc_us-gaap_GoodwillImpairmentLoss_C793F1465CF15657B52675E932505176" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_F9A6AFEF860651F2BEC8EE8B02CA2AA3" xlink:to="loc_us-gaap_GoodwillImpairmentLoss_C793F1465CF15657B52675E932505176" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ImpairmentOfIntangibleAssetsExcludingGoodwill" xlink:label="loc_us-gaap_ImpairmentOfIntangibleAssetsExcludingGoodwill_660C3993E54657CCA0E05E645A042493" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_F9A6AFEF860651F2BEC8EE8B02CA2AA3" xlink:to="loc_us-gaap_ImpairmentOfIntangibleAssetsExcludingGoodwill_660C3993E54657CCA0E05E645A042493" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/GoodwillAndOtherIntangiblesScheduleOfOtherIntangibleAssetsDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract" xlink:label="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_B5477B149997AE6A25C34A2112A55190" xlink:type="locator" />
    <link:loc xlink:href="endp-20190930.xsd#endp_ScheduleOfGoodwillAndOtherIntangiblesTable" xlink:label="loc_endp_ScheduleOfGoodwillAndOtherIntangiblesTable_710647EDE25B1EA849224A2112A5A7B5" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_B5477B149997AE6A25C34A2112A55190" xlink:to="loc_endp_ScheduleOfGoodwillAndOtherIntangiblesTable_710647EDE25B1EA849224A2112A5A7B5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_RangeAxis" xlink:label="loc_srt_RangeAxis_32DFB198D07B65E090CF4A2112A57C5D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_ScheduleOfGoodwillAndOtherIntangiblesTable_710647EDE25B1EA849224A2112A5A7B5" xlink:to="loc_srt_RangeAxis_32DFB198D07B65E090CF4A2112A57C5D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_RangeMember" xlink:label="loc_srt_RangeMember_18129FA51C6B56BC0F534A2112A6E986" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeAxis_32DFB198D07B65E090CF4A2112A57C5D" xlink:to="loc_srt_RangeMember_18129FA51C6B56BC0F534A2112A6E986" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_WeightedAverageMember" xlink:label="loc_srt_WeightedAverageMember_F02A153E0BCCA0199E9B4A2112A6D90F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_18129FA51C6B56BC0F534A2112A6E986" xlink:to="loc_srt_WeightedAverageMember_F02A153E0BCCA0199E9B4A2112A6D90F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis_73C3F2570086C66AFB2C4A2112A6CACF" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_ScheduleOfGoodwillAndOtherIntangiblesTable_710647EDE25B1EA849224A2112A5A7B5" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis_73C3F2570086C66AFB2C4A2112A6CACF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_740643306C7BC08F2C9B4A2112A6E21B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis_73C3F2570086C66AFB2C4A2112A6CACF" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_740643306C7BC08F2C9B4A2112A6E21B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_InProcessResearchAndDevelopmentMember" xlink:label="loc_us-gaap_InProcessResearchAndDevelopmentMember_100AF4DA9652E326E1C34A2112A7AC2E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_740643306C7BC08F2C9B4A2112A6E21B" xlink:to="loc_us-gaap_InProcessResearchAndDevelopmentMember_100AF4DA9652E326E1C34A2112A7AC2E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_FC19C54301389336F47A4A2112A70C53" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_ScheduleOfGoodwillAndOtherIntangiblesTable_710647EDE25B1EA849224A2112A5A7B5" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_FC19C54301389336F47A4A2112A70C53" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_2F75139A0B5FD29A13DD4A2112A743CD" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_FC19C54301389336F47A4A2112A70C53" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_2F75139A0B5FD29A13DD4A2112A743CD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LicensingAgreementsMember" xlink:label="loc_us-gaap_LicensingAgreementsMember_7A020F3F944B2F402A1B4A2112A740B6" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_2F75139A0B5FD29A13DD4A2112A743CD" xlink:to="loc_us-gaap_LicensingAgreementsMember_7A020F3F944B2F402A1B4A2112A740B6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_TradeNamesMember" xlink:label="loc_us-gaap_TradeNamesMember_75D80019767D555A46854A2112A84D46" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_2F75139A0B5FD29A13DD4A2112A743CD" xlink:to="loc_us-gaap_TradeNamesMember_75D80019767D555A46854A2112A84D46" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DevelopedTechnologyRightsMember" xlink:label="loc_us-gaap_DevelopedTechnologyRightsMember_C0ABE56290B39781CD1C4A2112A8A32A" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_2F75139A0B5FD29A13DD4A2112A743CD" xlink:to="loc_us-gaap_DevelopedTechnologyRightsMember_C0ABE56290B39781CD1C4A2112A8A32A" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_OtherIntangibleAssetsLineItems" xlink:label="loc_endp_OtherIntangibleAssetsLineItems_F15691CCA92537E06BA94A2112A88FA3" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_ScheduleOfGoodwillAndOtherIntangiblesTable_710647EDE25B1EA849224A2112A5A7B5" xlink:to="loc_endp_OtherIntangibleAssetsLineItems_F15691CCA92537E06BA94A2112A88FA3" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_OtherIntangibleAssetsCostBasisAbstract" xlink:label="loc_endp_OtherIntangibleAssetsCostBasisAbstract_89F5AA2CF179E493F1C54A2112A83B3E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_OtherIntangibleAssetsLineItems_F15691CCA92537E06BA94A2112A88FA3" xlink:to="loc_endp_OtherIntangibleAssetsCostBasisAbstract_89F5AA2CF179E493F1C54A2112A83B3E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IndefiniteLivedIntangibleAssetsRollForward" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsRollForward_65A9F55A682EC9D1863E4A2112A8BAFD" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_OtherIntangibleAssetsCostBasisAbstract_89F5AA2CF179E493F1C54A2112A83B3E" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsRollForward_65A9F55A682EC9D1863E4A2112A8BAFD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill_BEB534EB5DAEA1D128EA4A2112A90D6C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsRollForward_65A9F55A682EC9D1863E4A2112A8BAFD" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill_BEB534EB5DAEA1D128EA4A2112A90D6C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IndefinitelivedIntangibleAssetsAcquired" xlink:label="loc_us-gaap_IndefinitelivedIntangibleAssetsAcquired_AE2F306A81B1199B013C4A2112A9439A" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsRollForward_65A9F55A682EC9D1863E4A2112A8BAFD" xlink:to="loc_us-gaap_IndefinitelivedIntangibleAssetsAcquired_AE2F306A81B1199B013C4A2112A9439A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ImpairmentOfIntangibleAssetsIndefinitelivedExcludingGoodwill" xlink:label="loc_us-gaap_ImpairmentOfIntangibleAssetsIndefinitelivedExcludingGoodwill_FC4C875F34CD97D96F294A2112A900C3" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsRollForward_65A9F55A682EC9D1863E4A2112A8BAFD" xlink:to="loc_us-gaap_ImpairmentOfIntangibleAssetsIndefinitelivedExcludingGoodwill_FC4C875F34CD97D96F294A2112A900C3" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_IndefinitelivedIntangibleAssetsOther" xlink:label="loc_endp_IndefinitelivedIntangibleAssetsOther_E84E97B4B1A09F385F9D4A2112A92CC9" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsRollForward_65A9F55A682EC9D1863E4A2112A8BAFD" xlink:to="loc_endp_IndefinitelivedIntangibleAssetsOther_E84E97B4B1A09F385F9D4A2112A92CC9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IndefiniteLivedIntangibleAssetsForeignCurrencyTranslationGainLoss" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsForeignCurrencyTranslationGainLoss_B5F361AAC7A1DE803AA74A2112A95F9C" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsRollForward_65A9F55A682EC9D1863E4A2112A8BAFD" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsForeignCurrencyTranslationGainLoss_B5F361AAC7A1DE803AA74A2112A95F9C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill_3015A5E6BA6662B172A74A2112AA8363" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsRollForward_65A9F55A682EC9D1863E4A2112A8BAFD" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill_3015A5E6BA6662B172A74A2112AA8363" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsRollForward" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsRollForward_5B5BE9BF88ED02BFCD004A2112AA34F9" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_OtherIntangibleAssetsCostBasisAbstract_89F5AA2CF179E493F1C54A2112A83B3E" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsRollForward_5B5BE9BF88ED02BFCD004A2112AA34F9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsGross" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsGross_89830391325751BE56A44A2112AA2F56" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsRollForward_5B5BE9BF88ED02BFCD004A2112AA34F9" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsGross_89830391325751BE56A44A2112AA2F56" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FinitelivedIntangibleAssetsAcquired1" xlink:label="loc_us-gaap_FinitelivedIntangibleAssetsAcquired1_6EB4BE7D93C1DD8189364A2112AAD42A" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsRollForward_5B5BE9BF88ED02BFCD004A2112AA34F9" xlink:to="loc_us-gaap_FinitelivedIntangibleAssetsAcquired1_6EB4BE7D93C1DD8189364A2112AAD42A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ImpairmentOfIntangibleAssetsFinitelived" xlink:label="loc_us-gaap_ImpairmentOfIntangibleAssetsFinitelived_FB05BB042A89FBFD47D04A2112AA9DC2" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsRollForward_5B5BE9BF88ED02BFCD004A2112AA34F9" xlink:to="loc_us-gaap_ImpairmentOfIntangibleAssetsFinitelived_FB05BB042A89FBFD47D04A2112AA9DC2" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_FiniteLivedIntangibleAssetsOther" xlink:label="loc_endp_FiniteLivedIntangibleAssetsOther_149F9F91684E3E734DA44A2112ABCBB4" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsRollForward_5B5BE9BF88ED02BFCD004A2112AA34F9" xlink:to="loc_endp_FiniteLivedIntangibleAssetsOther_149F9F91684E3E734DA44A2112ABCBB4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsForeignCurrencyTranslationGainLoss" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsForeignCurrencyTranslationGainLoss_E0D0B6986A58915E2BE54A2112ABEFF5" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsRollForward_5B5BE9BF88ED02BFCD004A2112AA34F9" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsForeignCurrencyTranslationGainLoss_E0D0B6986A58915E2BE54A2112ABEFF5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsGross" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsGross_58F69DA6D8B35C7832C04A2112ABB116" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsRollForward_5B5BE9BF88ED02BFCD004A2112AA34F9" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsGross_58F69DA6D8B35C7832C04A2112ABB116" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_IntangibleAssetsGrossRollForward" xlink:label="loc_endp_IntangibleAssetsGrossRollForward_2C9D20BB19AD04E427754A2112AB0784" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_OtherIntangibleAssetsCostBasisAbstract_89F5AA2CF179E493F1C54A2112A83B3E" xlink:to="loc_endp_IntangibleAssetsGrossRollForward_2C9D20BB19AD04E427754A2112AB0784" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IntangibleAssetsGrossExcludingGoodwill" xlink:label="loc_us-gaap_IntangibleAssetsGrossExcludingGoodwill_27AC2402A02CE183BBD94A2112AB2BA9" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_IntangibleAssetsGrossRollForward_2C9D20BB19AD04E427754A2112AB0784" xlink:to="loc_us-gaap_IntangibleAssetsGrossExcludingGoodwill_27AC2402A02CE183BBD94A2112AB2BA9" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_IntangibleAssetsAcquired" xlink:label="loc_endp_IntangibleAssetsAcquired_824925A24C0012C32FD54A2112AB6946" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_IntangibleAssetsGrossRollForward_2C9D20BB19AD04E427754A2112AB0784" xlink:to="loc_endp_IntangibleAssetsAcquired_824925A24C0012C32FD54A2112AB6946" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ImpairmentOfIntangibleAssetsExcludingGoodwill" xlink:label="loc_us-gaap_ImpairmentOfIntangibleAssetsExcludingGoodwill_F3B9A26D66B8795EE3374A2112ACAED7" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2009/role/negatedTotalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_IntangibleAssetsGrossRollForward_2C9D20BB19AD04E427754A2112AB0784" xlink:to="loc_us-gaap_ImpairmentOfIntangibleAssetsExcludingGoodwill_F3B9A26D66B8795EE3374A2112ACAED7" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_IntangibleAssetsOther" xlink:label="loc_endp_IntangibleAssetsOther_9C29CA1BDD9A1E72AB064A2112ACA6DE" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2009/role/negatedTotalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_IntangibleAssetsGrossRollForward_2C9D20BB19AD04E427754A2112AB0784" xlink:to="loc_endp_IntangibleAssetsOther_9C29CA1BDD9A1E72AB064A2112ACA6DE" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_IntangibleAssetsForeignCurrencyTranslationGainLoss" xlink:label="loc_endp_IntangibleAssetsForeignCurrencyTranslationGainLoss_3EEFA4C46AC937F6E53E4A2112AC13C1" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_IntangibleAssetsGrossRollForward_2C9D20BB19AD04E427754A2112AB0784" xlink:to="loc_endp_IntangibleAssetsForeignCurrencyTranslationGainLoss_3EEFA4C46AC937F6E53E4A2112AC13C1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IntangibleAssetsGrossExcludingGoodwill" xlink:label="loc_us-gaap_IntangibleAssetsGrossExcludingGoodwill_7E8307223383E393B2E34A2112AC4B43" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_IntangibleAssetsGrossRollForward_2C9D20BB19AD04E427754A2112AB0784" xlink:to="loc_us-gaap_IntangibleAssetsGrossExcludingGoodwill_7E8307223383E393B2E34A2112AC4B43" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_FiniteLivedIntangibleAssetsAccumulatedAmortizationRollForward" xlink:label="loc_endp_FiniteLivedIntangibleAssetsAccumulatedAmortizationRollForward_477B1A4E1FFDF90D60544A2112ACA9D5" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_OtherIntangibleAssetsLineItems_F15691CCA92537E06BA94A2112A88FA3" xlink:to="loc_endp_FiniteLivedIntangibleAssetsAccumulatedAmortizationRollForward_477B1A4E1FFDF90D60544A2112ACA9D5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_4E9AC9B0866E5ABB5D934A2112AC1367" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2009/role/negatedPeriodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_FiniteLivedIntangibleAssetsAccumulatedAmortizationRollForward_477B1A4E1FFDF90D60544A2112ACA9D5" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_4E9AC9B0866E5ABB5D934A2112AC1367" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AmortizationOfIntangibleAssets" xlink:label="loc_us-gaap_AmortizationOfIntangibleAssets_47CB7AEB1836D1AA3B5C4A2112ADFE54" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_FiniteLivedIntangibleAssetsAccumulatedAmortizationRollForward_477B1A4E1FFDF90D60544A2112ACA9D5" xlink:to="loc_us-gaap_AmortizationOfIntangibleAssets_47CB7AEB1836D1AA3B5C4A2112ADFE54" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_ImpairmentofIntangibleAssetsFinitelivedEffectOnAccumulatedAmortization" xlink:label="loc_endp_ImpairmentofIntangibleAssetsFinitelivedEffectOnAccumulatedAmortization_7E0AEF94B2F0B431BB7E4A2112AD8EE7" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_FiniteLivedIntangibleAssetsAccumulatedAmortizationRollForward_477B1A4E1FFDF90D60544A2112ACA9D5" xlink:to="loc_endp_ImpairmentofIntangibleAssetsFinitelivedEffectOnAccumulatedAmortization_7E0AEF94B2F0B431BB7E4A2112AD8EE7" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_FiniteLivedIntangibleAssetsOtherAdjustmentsIncreaseDecreaseInAccumulatedAmortization" xlink:label="loc_endp_FiniteLivedIntangibleAssetsOtherAdjustmentsIncreaseDecreaseInAccumulatedAmortization_D16FF656E58555D6EE254A2112AD8ED2" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_FiniteLivedIntangibleAssetsAccumulatedAmortizationRollForward_477B1A4E1FFDF90D60544A2112ACA9D5" xlink:to="loc_endp_FiniteLivedIntangibleAssetsOtherAdjustmentsIncreaseDecreaseInAccumulatedAmortization_D16FF656E58555D6EE254A2112AD8ED2" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_FiniteLivedIntangibleAssetsTranslationAdjustmentsEffectOnAccumulatedAmortization" xlink:label="loc_endp_FiniteLivedIntangibleAssetsTranslationAdjustmentsEffectOnAccumulatedAmortization_56462F147577FCA8D32C4A2112ADCDAF" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_FiniteLivedIntangibleAssetsAccumulatedAmortizationRollForward_477B1A4E1FFDF90D60544A2112ACA9D5" xlink:to="loc_endp_FiniteLivedIntangibleAssetsTranslationAdjustmentsEffectOnAccumulatedAmortization_56462F147577FCA8D32C4A2112ADCDAF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_2F4B887DFB902A47F05E4A2112AD0BE5" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2009/role/negatedPeriodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_FiniteLivedIntangibleAssetsAccumulatedAmortizationRollForward_477B1A4E1FFDF90D60544A2112ACA9D5" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_2F4B887DFB902A47F05E4A2112AD0BE5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IntangibleAssetsNetExcludingGoodwill" xlink:label="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_125EA0FEA4E53ECCF3A74A2112AE841C" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_OtherIntangibleAssetsLineItems_F15691CCA92537E06BA94A2112A88FA3" xlink:to="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_125EA0FEA4E53ECCF3A74A2112AE841C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetUsefulLife" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetUsefulLife_216793BF7D7A132A24C64A2112AE0821" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_OtherIntangibleAssetsLineItems_F15691CCA92537E06BA94A2112A88FA3" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetUsefulLife_216793BF7D7A132A24C64A2112AE0821" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/GoodwillAndOtherIntangiblesTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract" xlink:label="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_C25060F9025C582AA544862E1C6692E9" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfGoodwillTextBlock" xlink:label="loc_us-gaap_ScheduleOfGoodwillTextBlock_095700A4DB9A5566B45DD2F66479F5EA" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_C25060F9025C582AA544862E1C6692E9" xlink:to="loc_us-gaap_ScheduleOfGoodwillTextBlock_095700A4DB9A5566B45DD2F66479F5EA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfIntangibleAssetsAndGoodwillTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfIntangibleAssetsAndGoodwillTableTextBlock_D394FC8846F75E61B92007DA5981AF24" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_C25060F9025C582AA544862E1C6692E9" xlink:to="loc_us-gaap_ScheduleOfIntangibleAssetsAndGoodwillTableTextBlock_D394FC8846F75E61B92007DA5981AF24" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleofFiniteLivedIntangibleAssetsFutureAmortizationExpenseTableTextBlock" xlink:label="loc_us-gaap_ScheduleofFiniteLivedIntangibleAssetsFutureAmortizationExpenseTableTextBlock_00AA7DDBBEC65969912DC829ED43969F" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_C25060F9025C582AA544862E1C6692E9" xlink:to="loc_us-gaap_ScheduleofFiniteLivedIntangibleAssetsFutureAmortizationExpenseTableTextBlock_00AA7DDBBEC65969912DC829ED43969F" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_ScheduleofIntangibleAssetImpairmentChargesIncludingGoodwillTableTextBlock" xlink:label="loc_endp_ScheduleofIntangibleAssetImpairmentChargesIncludingGoodwillTableTextBlock_BE9F102F51E7529FB0115266D15EDC73" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_C25060F9025C582AA544862E1C6692E9" xlink:to="loc_endp_ScheduleofIntangibleAssetImpairmentChargesIncludingGoodwillTableTextBlock_BE9F102F51E7529FB0115266D15EDC73" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/IncomeTaxes" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract_8CB96609238B54B1AE79C30EA1D88541" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeTaxDisclosureTextBlock" xlink:label="loc_us-gaap_IncomeTaxDisclosureTextBlock_454E007C5FE35E12B769FB6A2B30747C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_8CB96609238B54B1AE79C30EA1D88541" xlink:to="loc_us-gaap_IncomeTaxDisclosureTextBlock_454E007C5FE35E12B769FB6A2B30747C" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/IncomeTaxesScheduleOfComponentsOfContinuingOperationsBeforeIncomeTaxIncomeTaxExpenseEffectiveTaxRateDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract_B842D0E5F8C8A83730BBEFF65CE84024" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_14BCE874E57BC3E3922BEFF65CE8850C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_B842D0E5F8C8A83730BBEFF65CE84024" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_14BCE874E57BC3E3922BEFF65CE8850C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeTaxExpenseBenefit" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_B1A2DF896A65E56F906BEFF65CE82B23" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_B842D0E5F8C8A83730BBEFF65CE84024" xlink:to="loc_us-gaap_IncomeTaxExpenseBenefit_B1A2DF896A65E56F906BEFF65CE82B23" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EffectiveIncomeTaxRateContinuingOperations" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperations_EB7ADC8924E2CD3E013DEFF65CE81BB3" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_B842D0E5F8C8A83730BBEFF65CE84024" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperations_EB7ADC8924E2CD3E013DEFF65CE81BB3" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/IncomeTaxesTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract_A0898BBFC61F572DA66702113EE9E905" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfComponentsOfIncomeTaxExpenseBenefitTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfComponentsOfIncomeTaxExpenseBenefitTableTextBlock_6D824A55FF955C08935AB816661D5764" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_A0898BBFC61F572DA66702113EE9E905" xlink:to="loc_us-gaap_ScheduleOfComponentsOfIncomeTaxExpenseBenefitTableTextBlock_6D824A55FF955C08935AB816661D5764" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/Inventories" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_InventoryDisclosureAbstract" xlink:label="loc_us-gaap_InventoryDisclosureAbstract_7172939007D6596593141AE26E3A480D" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_InventoryDisclosureTextBlock" xlink:label="loc_us-gaap_InventoryDisclosureTextBlock_5A8F7886E5855928950764B7A7843C3B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InventoryDisclosureAbstract_7172939007D6596593141AE26E3A480D" xlink:to="loc_us-gaap_InventoryDisclosureTextBlock_5A8F7886E5855928950764B7A7843C3B" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/InventoriesDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_InventoryDisclosureAbstract" xlink:label="loc_us-gaap_InventoryDisclosureAbstract_10C67A275B4E50A3B01F930C822E5F1F" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_InventoryRawMaterialsNetOfReserves" xlink:label="loc_us-gaap_InventoryRawMaterialsNetOfReserves_48CA9CEE883950C6BA8A1ED07A7D3230" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InventoryDisclosureAbstract_10C67A275B4E50A3B01F930C822E5F1F" xlink:to="loc_us-gaap_InventoryRawMaterialsNetOfReserves_48CA9CEE883950C6BA8A1ED07A7D3230" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_InventoryWorkInProcessNetOfReserves" xlink:label="loc_us-gaap_InventoryWorkInProcessNetOfReserves_338742A58F9A59B9827A7AE34B054442" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InventoryDisclosureAbstract_10C67A275B4E50A3B01F930C822E5F1F" xlink:to="loc_us-gaap_InventoryWorkInProcessNetOfReserves_338742A58F9A59B9827A7AE34B054442" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_InventoryFinishedGoodsNetOfReserves" xlink:label="loc_us-gaap_InventoryFinishedGoodsNetOfReserves_9D4ADF4FEEE75938849FEC728D6E2021" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InventoryDisclosureAbstract_10C67A275B4E50A3B01F930C822E5F1F" xlink:to="loc_us-gaap_InventoryFinishedGoodsNetOfReserves_9D4ADF4FEEE75938849FEC728D6E2021" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_InventoryNet" xlink:label="loc_us-gaap_InventoryNet_50073D2CF5595CC7A26194678ED5E222" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InventoryDisclosureAbstract_10C67A275B4E50A3B01F930C822E5F1F" xlink:to="loc_us-gaap_InventoryNet_50073D2CF5595CC7A26194678ED5E222" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_InventoryNoncurrent" xlink:label="loc_us-gaap_InventoryNoncurrent_302877497268503C8C91B1D6FE9C52DF" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InventoryDisclosureAbstract_10C67A275B4E50A3B01F930C822E5F1F" xlink:to="loc_us-gaap_InventoryNoncurrent_302877497268503C8C91B1D6FE9C52DF" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_InventoryNotYetAvailableForSaleNet" xlink:label="loc_endp_InventoryNotYetAvailableForSaleNet_9C9AB9B54D5A5EEDB22AEE0365C6860D" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InventoryDisclosureAbstract_10C67A275B4E50A3B01F930C822E5F1F" xlink:to="loc_endp_InventoryNotYetAvailableForSaleNet_9C9AB9B54D5A5EEDB22AEE0365C6860D" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/InventoriesTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_InventoryDisclosureAbstract" xlink:label="loc_us-gaap_InventoryDisclosureAbstract_FA3F937E236351EA97D507B9B6C1B46B" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfInventoryCurrentTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfInventoryCurrentTableTextBlock_7F89E670BF8450448F1D93C71DBAC996" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InventoryDisclosureAbstract_FA3F937E236351EA97D507B9B6C1B46B" xlink:to="loc_us-gaap_ScheduleOfInventoryCurrentTableTextBlock_7F89E670BF8450448F1D93C71DBAC996" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/Leases" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LeasesAbstract" xlink:label="loc_us-gaap_LeasesAbstract_67C3C6E0BE6455D68240890092CCE636" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LesseeOperatingLeasesTextBlock" xlink:label="loc_us-gaap_LesseeOperatingLeasesTextBlock_E93795849F725B05BCEAF91D09EE58D7" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_67C3C6E0BE6455D68240890092CCE636" xlink:to="loc_us-gaap_LesseeOperatingLeasesTextBlock_E93795849F725B05BCEAF91D09EE58D7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LesseeFinanceLeasesTextBlock" xlink:label="loc_us-gaap_LesseeFinanceLeasesTextBlock_9FFEBC96726051618249733683D84A4E" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_67C3C6E0BE6455D68240890092CCE636" xlink:to="loc_us-gaap_LesseeFinanceLeasesTextBlock_9FFEBC96726051618249733683D84A4E" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/LeasesAssetsAndLiabilitiesDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LeasesAbstract" xlink:label="loc_us-gaap_LeasesAbstract_BDCDA87DCDE2582DAB4285A91CB5777E" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AssetsNoncurrentAbstract" xlink:label="loc_us-gaap_AssetsNoncurrentAbstract_38118671B11353FC842D844DD1976B83" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_BDCDA87DCDE2582DAB4285A91CB5777E" xlink:to="loc_us-gaap_AssetsNoncurrentAbstract_38118671B11353FC842D844DD1976B83" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OperatingLeaseRightOfUseAsset" xlink:label="loc_us-gaap_OperatingLeaseRightOfUseAsset_FB561F621FF65ED6A088B92C18D91621" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsNoncurrentAbstract_38118671B11353FC842D844DD1976B83" xlink:to="loc_us-gaap_OperatingLeaseRightOfUseAsset_FB561F621FF65ED6A088B92C18D91621" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FinanceLeaseRightOfUseAsset" xlink:label="loc_us-gaap_FinanceLeaseRightOfUseAsset_1A1BFED1695A50A388636FD86BA4F274" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsNoncurrentAbstract_38118671B11353FC842D844DD1976B83" xlink:to="loc_us-gaap_FinanceLeaseRightOfUseAsset_1A1BFED1695A50A388636FD86BA4F274" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_LeaseRightofUseAsset" xlink:label="loc_endp_LeaseRightofUseAsset_958A29C33EA25105916D43EA99DD64A0" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsNoncurrentAbstract_38118671B11353FC842D844DD1976B83" xlink:to="loc_endp_LeaseRightofUseAsset_958A29C33EA25105916D43EA99DD64A0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LiabilitiesNoncurrentAbstract" xlink:label="loc_us-gaap_LiabilitiesNoncurrentAbstract_8DB8BF2BB0A55C8CAACB2551E4066C19" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_BDCDA87DCDE2582DAB4285A91CB5777E" xlink:to="loc_us-gaap_LiabilitiesNoncurrentAbstract_8DB8BF2BB0A55C8CAACB2551E4066C19" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OperatingLeaseLiabilityCurrent" xlink:label="loc_us-gaap_OperatingLeaseLiabilityCurrent_C00EBE03295658F981C7EA15561083E0" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesNoncurrentAbstract_8DB8BF2BB0A55C8CAACB2551E4066C19" xlink:to="loc_us-gaap_OperatingLeaseLiabilityCurrent_C00EBE03295658F981C7EA15561083E0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OperatingLeaseLiabilityNoncurrent" xlink:label="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_FF0F694E88D35167BF5FB8CF0501785B" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesNoncurrentAbstract_8DB8BF2BB0A55C8CAACB2551E4066C19" xlink:to="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_FF0F694E88D35167BF5FB8CF0501785B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OperatingLeaseLiability" xlink:label="loc_us-gaap_OperatingLeaseLiability_3E9E2CBDF674554EAAF37A8503EE4F12" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesNoncurrentAbstract_8DB8BF2BB0A55C8CAACB2551E4066C19" xlink:to="loc_us-gaap_OperatingLeaseLiability_3E9E2CBDF674554EAAF37A8503EE4F12" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AssetsAndLiabilitiesLesseeAbstract" xlink:label="loc_us-gaap_AssetsAndLiabilitiesLesseeAbstract_83FC87A8B1B45E46AFABA4F0B51665D6" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_BDCDA87DCDE2582DAB4285A91CB5777E" xlink:to="loc_us-gaap_AssetsAndLiabilitiesLesseeAbstract_83FC87A8B1B45E46AFABA4F0B51665D6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FinanceLeaseLiabilityCurrent" xlink:label="loc_us-gaap_FinanceLeaseLiabilityCurrent_065E5682DB115E12A2EB2BC76C5DB524" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAndLiabilitiesLesseeAbstract_83FC87A8B1B45E46AFABA4F0B51665D6" xlink:to="loc_us-gaap_FinanceLeaseLiabilityCurrent_065E5682DB115E12A2EB2BC76C5DB524" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FinanceLeaseLiabilityNoncurrent" xlink:label="loc_us-gaap_FinanceLeaseLiabilityNoncurrent_EA934EA31B6B57468EE55374D459310B" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAndLiabilitiesLesseeAbstract_83FC87A8B1B45E46AFABA4F0B51665D6" xlink:to="loc_us-gaap_FinanceLeaseLiabilityNoncurrent_EA934EA31B6B57468EE55374D459310B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FinanceLeaseLiability" xlink:label="loc_us-gaap_FinanceLeaseLiability_C6FCA8A7B2BD5742B93BAF6B6CE54F1A" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAndLiabilitiesLesseeAbstract_83FC87A8B1B45E46AFABA4F0B51665D6" xlink:to="loc_us-gaap_FinanceLeaseLiability_C6FCA8A7B2BD5742B93BAF6B6CE54F1A" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/LeasesCashFlowAndSupplementalNoncashInformationDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LeasesAbstract" xlink:label="loc_us-gaap_LeasesAbstract_1579CB478EA25E7C83476F47DD365145" xlink:type="locator" />
    <link:loc xlink:href="endp-20190930.xsd#endp_CashFlowLesseeAbstract" xlink:label="loc_endp_CashFlowLesseeAbstract_7C18C516E051555F8F7253E37E39BFEF" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_1579CB478EA25E7C83476F47DD365145" xlink:to="loc_endp_CashFlowLesseeAbstract_7C18C516E051555F8F7253E37E39BFEF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OperatingLeasePayments" xlink:label="loc_us-gaap_OperatingLeasePayments_E675EFFFD4065AE18F6EE2CB220D3599" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_CashFlowLesseeAbstract_7C18C516E051555F8F7253E37E39BFEF" xlink:to="loc_us-gaap_OperatingLeasePayments_E675EFFFD4065AE18F6EE2CB220D3599" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FinanceLeaseInterestPaymentOnLiability" xlink:label="loc_us-gaap_FinanceLeaseInterestPaymentOnLiability_B059F721909D5AD38903361802F03F90" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_CashFlowLesseeAbstract_7C18C516E051555F8F7253E37E39BFEF" xlink:to="loc_us-gaap_FinanceLeaseInterestPaymentOnLiability_B059F721909D5AD38903361802F03F90" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FinanceLeasePrincipalPayments" xlink:label="loc_us-gaap_FinanceLeasePrincipalPayments_202388D85AD55AF6B513018FC947FDEC" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_CashFlowLesseeAbstract_7C18C516E051555F8F7253E37E39BFEF" xlink:to="loc_us-gaap_FinanceLeasePrincipalPayments_202388D85AD55AF6B513018FC947FDEC" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_RightofUseAssetObtainedInExchangeForLeaseLiabilityAbstract" xlink:label="loc_endp_RightofUseAssetObtainedInExchangeForLeaseLiabilityAbstract_971B732A7BE45C6D8E7B5318C02C2816" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_1579CB478EA25E7C83476F47DD365145" xlink:to="loc_endp_RightofUseAssetObtainedInExchangeForLeaseLiabilityAbstract_971B732A7BE45C6D8E7B5318C02C2816" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability" xlink:label="loc_us-gaap_RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability_E07E0D41F31B5EE892E6CD26AA32B2B6" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_RightofUseAssetObtainedInExchangeForLeaseLiabilityAbstract_971B732A7BE45C6D8E7B5318C02C2816" xlink:to="loc_us-gaap_RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability_E07E0D41F31B5EE892E6CD26AA32B2B6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RightOfUseAssetObtainedInExchangeForFinanceLeaseLiability" xlink:label="loc_us-gaap_RightOfUseAssetObtainedInExchangeForFinanceLeaseLiability_106563F8931456C98826F84AC244DC22" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_RightofUseAssetObtainedInExchangeForLeaseLiabilityAbstract_971B732A7BE45C6D8E7B5318C02C2816" xlink:to="loc_us-gaap_RightOfUseAssetObtainedInExchangeForFinanceLeaseLiability_106563F8931456C98826F84AC244DC22" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/LeasesComponentsOfLeaseExpenseDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LeasesAbstract" xlink:label="loc_us-gaap_LeasesAbstract_6A2B5C485F26558882229215D8516907" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OperatingLeaseCost" xlink:label="loc_us-gaap_OperatingLeaseCost_3B8D465C8C9B5CD395CE08774B9BF7DB" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_6A2B5C485F26558882229215D8516907" xlink:to="loc_us-gaap_OperatingLeaseCost_3B8D465C8C9B5CD395CE08774B9BF7DB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LeaseCostAbstract" xlink:label="loc_us-gaap_LeaseCostAbstract_9167FF3B600B5BE482426C641CEE179E" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_6A2B5C485F26558882229215D8516907" xlink:to="loc_us-gaap_LeaseCostAbstract_9167FF3B600B5BE482426C641CEE179E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FinanceLeaseRightOfUseAssetAmortization" xlink:label="loc_us-gaap_FinanceLeaseRightOfUseAssetAmortization_2E3121D169D85AC0A9341FD130DA5004" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeaseCostAbstract_9167FF3B600B5BE482426C641CEE179E" xlink:to="loc_us-gaap_FinanceLeaseRightOfUseAssetAmortization_2E3121D169D85AC0A9341FD130DA5004" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FinanceLeaseInterestExpense" xlink:label="loc_us-gaap_FinanceLeaseInterestExpense_C890A6512B9A5E9AA2B564AEEFDAC9DC" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeaseCostAbstract_9167FF3B600B5BE482426C641CEE179E" xlink:to="loc_us-gaap_FinanceLeaseInterestExpense_C890A6512B9A5E9AA2B564AEEFDAC9DC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OperatingLeasesLeaseIncomeAbstract" xlink:label="loc_us-gaap_OperatingLeasesLeaseIncomeAbstract_5EEC1B9305BF5D5F89DED63202F33145" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_6A2B5C485F26558882229215D8516907" xlink:to="loc_us-gaap_OperatingLeasesLeaseIncomeAbstract_5EEC1B9305BF5D5F89DED63202F33145" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_VariableLeaseCost" xlink:label="loc_us-gaap_VariableLeaseCost_3B7517960F4856008DB909AAAD81F308" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeasesLeaseIncomeAbstract_5EEC1B9305BF5D5F89DED63202F33145" xlink:to="loc_us-gaap_VariableLeaseCost_3B7517960F4856008DB909AAAD81F308" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SubleaseIncome" xlink:label="loc_us-gaap_SubleaseIncome_79530B800A5E515E87F91A8824C18DB3" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeasesLeaseIncomeAbstract_5EEC1B9305BF5D5F89DED63202F33145" xlink:to="loc_us-gaap_SubleaseIncome_79530B800A5E515E87F91A8824C18DB3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LesseeLeaseDescriptionTable" xlink:label="loc_us-gaap_LesseeLeaseDescriptionTable_F525B65C3CEA57F689781000AF024B7D" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_6A2B5C485F26558882229215D8516907" xlink:to="loc_us-gaap_LesseeLeaseDescriptionTable_F525B65C3CEA57F689781000AF024B7D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeStatementLocationAxis" xlink:label="loc_us-gaap_IncomeStatementLocationAxis_E6478513988C5986B20B626705B6A72A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionTable_F525B65C3CEA57F689781000AF024B7D" xlink:to="loc_us-gaap_IncomeStatementLocationAxis_E6478513988C5986B20B626705B6A72A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeStatementLocationDomain" xlink:label="loc_us-gaap_IncomeStatementLocationDomain_C5EE4D9CA2D45BA0A7A09B7EB3F67028" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationAxis_E6478513988C5986B20B626705B6A72A" xlink:to="loc_us-gaap_IncomeStatementLocationDomain_C5EE4D9CA2D45BA0A7A09B7EB3F67028" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CostOfSalesMember" xlink:label="loc_us-gaap_CostOfSalesMember_7963B883F41A5E72A00054F00EDE1418" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_C5EE4D9CA2D45BA0A7A09B7EB3F67028" xlink:to="loc_us-gaap_CostOfSalesMember_7963B883F41A5E72A00054F00EDE1418" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SellingGeneralAndAdministrativeExpensesMember" xlink:label="loc_us-gaap_SellingGeneralAndAdministrativeExpensesMember_5B0FFEE4C87C5274BE9DF0608E717FCB" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_C5EE4D9CA2D45BA0A7A09B7EB3F67028" xlink:to="loc_us-gaap_SellingGeneralAndAdministrativeExpensesMember_5B0FFEE4C87C5274BE9DF0608E717FCB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ResearchAndDevelopmentExpenseMember" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpenseMember_27F8A195A56753498A012DC970D5ED1D" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_C5EE4D9CA2D45BA0A7A09B7EB3F67028" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpenseMember_27F8A195A56753498A012DC970D5ED1D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LesseeLeaseDescriptionLineItems" xlink:label="loc_us-gaap_LesseeLeaseDescriptionLineItems_CF862C0835AE5E0FB92F9B255C41E3CE" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionTable_F525B65C3CEA57F689781000AF024B7D" xlink:to="loc_us-gaap_LesseeLeaseDescriptionLineItems_CF862C0835AE5E0FB92F9B255C41E3CE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LeaseCost" xlink:label="loc_us-gaap_LeaseCost_8DBB398C7CC15313A6059AFB6638894E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_CF862C0835AE5E0FB92F9B255C41E3CE" xlink:to="loc_us-gaap_LeaseCost_8DBB398C7CC15313A6059AFB6638894E" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/LeasesFutureMinimumLeasePaymentObligationsUnderOperatingAndCapitalLeasesDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LeasesAbstract" xlink:label="loc_us-gaap_LeasesAbstract_A1CC5A7069DB5DF9B76E1DA495DAD49E" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LeasesCapitalAbstract" xlink:label="loc_us-gaap_LeasesCapitalAbstract_1D7194A8916A5BEC9116C12D5BB72FA0" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_A1CC5A7069DB5DF9B76E1DA495DAD49E" xlink:to="loc_us-gaap_LeasesCapitalAbstract_1D7194A8916A5BEC9116C12D5BB72FA0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CapitalLeasesFutureMinimumPaymentsRemainderOfFiscalYear" xlink:label="loc_us-gaap_CapitalLeasesFutureMinimumPaymentsRemainderOfFiscalYear_7EBF97A36D0F5405A1C9C3E32993FFFA" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesCapitalAbstract_1D7194A8916A5BEC9116C12D5BB72FA0" xlink:to="loc_us-gaap_CapitalLeasesFutureMinimumPaymentsRemainderOfFiscalYear_7EBF97A36D0F5405A1C9C3E32993FFFA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CapitalLeasesFutureMinimumPaymentsDueInTwoYears" xlink:label="loc_us-gaap_CapitalLeasesFutureMinimumPaymentsDueInTwoYears_A8CB0E0517BE564EB37CC5F243CA9EAA" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesCapitalAbstract_1D7194A8916A5BEC9116C12D5BB72FA0" xlink:to="loc_us-gaap_CapitalLeasesFutureMinimumPaymentsDueInTwoYears_A8CB0E0517BE564EB37CC5F243CA9EAA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CapitalLeasesFutureMinimumPaymentsDueInThreeYears" xlink:label="loc_us-gaap_CapitalLeasesFutureMinimumPaymentsDueInThreeYears_7934938B5F80554C9BA3597438A08190" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesCapitalAbstract_1D7194A8916A5BEC9116C12D5BB72FA0" xlink:to="loc_us-gaap_CapitalLeasesFutureMinimumPaymentsDueInThreeYears_7934938B5F80554C9BA3597438A08190" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CapitalLeasesFutureMinimumPaymentsDueInFourYears" xlink:label="loc_us-gaap_CapitalLeasesFutureMinimumPaymentsDueInFourYears_B7714D64CA835ED8B13B62F58DC92CD3" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesCapitalAbstract_1D7194A8916A5BEC9116C12D5BB72FA0" xlink:to="loc_us-gaap_CapitalLeasesFutureMinimumPaymentsDueInFourYears_B7714D64CA835ED8B13B62F58DC92CD3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CapitalLeasesFutureMinimumPaymentsDueInFiveYears" xlink:label="loc_us-gaap_CapitalLeasesFutureMinimumPaymentsDueInFiveYears_0040F05CE293524191C7BE847767776F" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesCapitalAbstract_1D7194A8916A5BEC9116C12D5BB72FA0" xlink:to="loc_us-gaap_CapitalLeasesFutureMinimumPaymentsDueInFiveYears_0040F05CE293524191C7BE847767776F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CapitalLeasesFutureMinimumPaymentsDueThereafter" xlink:label="loc_us-gaap_CapitalLeasesFutureMinimumPaymentsDueThereafter_B3E607B71D8F5FCC9A4F87DA8EA8EF4D" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesCapitalAbstract_1D7194A8916A5BEC9116C12D5BB72FA0" xlink:to="loc_us-gaap_CapitalLeasesFutureMinimumPaymentsDueThereafter_B3E607B71D8F5FCC9A4F87DA8EA8EF4D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CapitalLeasesFutureMinimumPaymentsDue" xlink:label="loc_us-gaap_CapitalLeasesFutureMinimumPaymentsDue_CD5232B196AE5C18A591C811191578D6" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesCapitalAbstract_1D7194A8916A5BEC9116C12D5BB72FA0" xlink:to="loc_us-gaap_CapitalLeasesFutureMinimumPaymentsDue_CD5232B196AE5C18A591C811191578D6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CapitalLeasesFutureMinimumPaymentsInterestIncludedInPayments" xlink:label="loc_us-gaap_CapitalLeasesFutureMinimumPaymentsInterestIncludedInPayments_2964B5B0358659429A326F6BB0DF21E4" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesCapitalAbstract_1D7194A8916A5BEC9116C12D5BB72FA0" xlink:to="loc_us-gaap_CapitalLeasesFutureMinimumPaymentsInterestIncludedInPayments_2964B5B0358659429A326F6BB0DF21E4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CapitalLeasesFutureMinimumPaymentsPresentValueOfNetMinimumPayments" xlink:label="loc_us-gaap_CapitalLeasesFutureMinimumPaymentsPresentValueOfNetMinimumPayments_11432A096893592DB4A535BBD4B602FB" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesCapitalAbstract_1D7194A8916A5BEC9116C12D5BB72FA0" xlink:to="loc_us-gaap_CapitalLeasesFutureMinimumPaymentsPresentValueOfNetMinimumPayments_11432A096893592DB4A535BBD4B602FB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CapitalLeaseObligationsCurrent" xlink:label="loc_us-gaap_CapitalLeaseObligationsCurrent_71FEC8AB6C105B99BD5C55A34CA28C00" xlink:type="locator" />
    <link:presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesCapitalAbstract_1D7194A8916A5BEC9116C12D5BB72FA0" xlink:to="loc_us-gaap_CapitalLeaseObligationsCurrent_71FEC8AB6C105B99BD5C55A34CA28C00" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CapitalLeaseObligationsNoncurrent" xlink:label="loc_us-gaap_CapitalLeaseObligationsNoncurrent_5E3F3DF776CD56CC82407702B3119350" xlink:type="locator" />
    <link:presentationArc order="11" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesCapitalAbstract_1D7194A8916A5BEC9116C12D5BB72FA0" xlink:to="loc_us-gaap_CapitalLeaseObligationsNoncurrent_5E3F3DF776CD56CC82407702B3119350" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LeasesOperatingAbstract" xlink:label="loc_us-gaap_LeasesOperatingAbstract_652994CD8EE25170A555182DBD148F6C" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_A1CC5A7069DB5DF9B76E1DA495DAD49E" xlink:to="loc_us-gaap_LeasesOperatingAbstract_652994CD8EE25170A555182DBD148F6C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OperatingLeasesFutureMinimumPaymentsRemainderOfFiscalYear" xlink:label="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsRemainderOfFiscalYear_CE427720E8055E4298455DA3A1430AEB" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesOperatingAbstract_652994CD8EE25170A555182DBD148F6C" xlink:to="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsRemainderOfFiscalYear_CE427720E8055E4298455DA3A1430AEB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OperatingLeasesFutureMinimumPaymentsDueInTwoYears" xlink:label="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueInTwoYears_FBE1C761F1445E058E7999E481A38A88" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesOperatingAbstract_652994CD8EE25170A555182DBD148F6C" xlink:to="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueInTwoYears_FBE1C761F1445E058E7999E481A38A88" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OperatingLeasesFutureMinimumPaymentsDueInThreeYears" xlink:label="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueInThreeYears_2FD86FD222C25F68939A8A5321B5D359" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesOperatingAbstract_652994CD8EE25170A555182DBD148F6C" xlink:to="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueInThreeYears_2FD86FD222C25F68939A8A5321B5D359" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OperatingLeasesFutureMinimumPaymentsDueInFourYears" xlink:label="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueInFourYears_EA264C327D9F5EC2BC69AB6EBD4D4B93" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesOperatingAbstract_652994CD8EE25170A555182DBD148F6C" xlink:to="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueInFourYears_EA264C327D9F5EC2BC69AB6EBD4D4B93" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OperatingLeasesFutureMinimumPaymentsDueInFiveYears" xlink:label="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueInFiveYears_9042F48CD29951B19077AC386290AA30" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesOperatingAbstract_652994CD8EE25170A555182DBD148F6C" xlink:to="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueInFiveYears_9042F48CD29951B19077AC386290AA30" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OperatingLeasesFutureMinimumPaymentsDueThereafter" xlink:label="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueThereafter_982CF852ED9C5D6E8B01D48FE5BE6CD7" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesOperatingAbstract_652994CD8EE25170A555182DBD148F6C" xlink:to="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueThereafter_982CF852ED9C5D6E8B01D48FE5BE6CD7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OperatingLeasesFutureMinimumPaymentsDue" xlink:label="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDue_18820D2B61975478BEA93A88838F888B" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesOperatingAbstract_652994CD8EE25170A555182DBD148F6C" xlink:to="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDue_18820D2B61975478BEA93A88838F888B" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/LeasesMaturitiesOfOperatingAndFinanceLeaseLiabilitiesDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LeasesAbstract" xlink:label="loc_us-gaap_LeasesAbstract_EB4670A232B3553E98CBD1C08B766AE6" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OperatingLeaseLiabilitiesPaymentsDueAbstract" xlink:label="loc_us-gaap_OperatingLeaseLiabilitiesPaymentsDueAbstract_4F6565B4C2D05098AF4298A2B46B5323" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_EB4670A232B3553E98CBD1C08B766AE6" xlink:to="loc_us-gaap_OperatingLeaseLiabilitiesPaymentsDueAbstract_4F6565B4C2D05098AF4298A2B46B5323" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear_FC118685F4F7556E93EC35ACB45598F8" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeaseLiabilitiesPaymentsDueAbstract_4F6565B4C2D05098AF4298A2B46B5323" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear_FC118685F4F7556E93EC35ACB45598F8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo_1B87F07533F95599B7B79B63315CAFCD" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeaseLiabilitiesPaymentsDueAbstract_4F6565B4C2D05098AF4298A2B46B5323" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo_1B87F07533F95599B7B79B63315CAFCD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree_213E05BDFB195152B0766DC71DD9DA0B" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeaseLiabilitiesPaymentsDueAbstract_4F6565B4C2D05098AF4298A2B46B5323" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree_213E05BDFB195152B0766DC71DD9DA0B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour_42D78970DD5355D0824676675A9BC06C" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeaseLiabilitiesPaymentsDueAbstract_4F6565B4C2D05098AF4298A2B46B5323" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour_42D78970DD5355D0824676675A9BC06C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFive" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFive_D149E7B46F79590DA8B86FE35ECCDCD1" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeaseLiabilitiesPaymentsDueAbstract_4F6565B4C2D05098AF4298A2B46B5323" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFive_D149E7B46F79590DA8B86FE35ECCDCD1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueAfterYearFive" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueAfterYearFive_06C0B4CE064A5BC09F48B45DF0866828" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeaseLiabilitiesPaymentsDueAbstract_4F6565B4C2D05098AF4298A2B46B5323" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueAfterYearFive_06C0B4CE064A5BC09F48B45DF0866828" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_C4E0AA65DDCC507194F7DE4AFE8C58C2" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeaseLiabilitiesPaymentsDueAbstract_4F6565B4C2D05098AF4298A2B46B5323" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_C4E0AA65DDCC507194F7DE4AFE8C58C2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount_D07CAD8CAEF15F15A3577862ABAA000C" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeaseLiabilitiesPaymentsDueAbstract_4F6565B4C2D05098AF4298A2B46B5323" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount_D07CAD8CAEF15F15A3577862ABAA000C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OperatingLeaseLiability" xlink:label="loc_us-gaap_OperatingLeaseLiability_2F24A6E273485703BCFAB464664F7189" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeaseLiabilitiesPaymentsDueAbstract_4F6565B4C2D05098AF4298A2B46B5323" xlink:to="loc_us-gaap_OperatingLeaseLiability_2F24A6E273485703BCFAB464664F7189" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FinanceLeaseLiabilitiesPaymentsDueAbstract" xlink:label="loc_us-gaap_FinanceLeaseLiabilitiesPaymentsDueAbstract_025A180F130F55019578C169D943DF1F" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_EB4670A232B3553E98CBD1C08B766AE6" xlink:to="loc_us-gaap_FinanceLeaseLiabilitiesPaymentsDueAbstract_025A180F130F55019578C169D943DF1F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FinanceLeaseLiabilityPaymentsRemainderOfFiscalYear" xlink:label="loc_us-gaap_FinanceLeaseLiabilityPaymentsRemainderOfFiscalYear_F814968D80BA51DC8E6754C2F94D65DA" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinanceLeaseLiabilitiesPaymentsDueAbstract_025A180F130F55019578C169D943DF1F" xlink:to="loc_us-gaap_FinanceLeaseLiabilityPaymentsRemainderOfFiscalYear_F814968D80BA51DC8E6754C2F94D65DA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FinanceLeaseLiabilityPaymentsDueYearTwo" xlink:label="loc_us-gaap_FinanceLeaseLiabilityPaymentsDueYearTwo_17AB5A48AECB59E8BFBE00A3B4E1DBD5" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinanceLeaseLiabilitiesPaymentsDueAbstract_025A180F130F55019578C169D943DF1F" xlink:to="loc_us-gaap_FinanceLeaseLiabilityPaymentsDueYearTwo_17AB5A48AECB59E8BFBE00A3B4E1DBD5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FinanceLeaseLiabilityPaymentsDueYearThree" xlink:label="loc_us-gaap_FinanceLeaseLiabilityPaymentsDueYearThree_FD018B7F9D945359963DBE76B32BE395" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinanceLeaseLiabilitiesPaymentsDueAbstract_025A180F130F55019578C169D943DF1F" xlink:to="loc_us-gaap_FinanceLeaseLiabilityPaymentsDueYearThree_FD018B7F9D945359963DBE76B32BE395" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FinanceLeaseLiabilityPaymentsDueYearFour" xlink:label="loc_us-gaap_FinanceLeaseLiabilityPaymentsDueYearFour_51F722D6DBB05751B267785433FA94DA" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinanceLeaseLiabilitiesPaymentsDueAbstract_025A180F130F55019578C169D943DF1F" xlink:to="loc_us-gaap_FinanceLeaseLiabilityPaymentsDueYearFour_51F722D6DBB05751B267785433FA94DA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FinanceLeaseLiabilityPaymentsDueYearFive" xlink:label="loc_us-gaap_FinanceLeaseLiabilityPaymentsDueYearFive_8716E8882B305F1892B8412F9A5C851C" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinanceLeaseLiabilitiesPaymentsDueAbstract_025A180F130F55019578C169D943DF1F" xlink:to="loc_us-gaap_FinanceLeaseLiabilityPaymentsDueYearFive_8716E8882B305F1892B8412F9A5C851C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FinanceLeaseLiabilityPaymentsDueAfterYearFive" xlink:label="loc_us-gaap_FinanceLeaseLiabilityPaymentsDueAfterYearFive_7F01CD99A691503BB28B873CC8B8EF4C" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinanceLeaseLiabilitiesPaymentsDueAbstract_025A180F130F55019578C169D943DF1F" xlink:to="loc_us-gaap_FinanceLeaseLiabilityPaymentsDueAfterYearFive_7F01CD99A691503BB28B873CC8B8EF4C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FinanceLeaseLiabilityPaymentsDue" xlink:label="loc_us-gaap_FinanceLeaseLiabilityPaymentsDue_A06BF387D78554758575638DBE82F7FA" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinanceLeaseLiabilitiesPaymentsDueAbstract_025A180F130F55019578C169D943DF1F" xlink:to="loc_us-gaap_FinanceLeaseLiabilityPaymentsDue_A06BF387D78554758575638DBE82F7FA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FinanceLeaseLiabilityUndiscountedExcessAmount" xlink:label="loc_us-gaap_FinanceLeaseLiabilityUndiscountedExcessAmount_607CEDE6DE49583493E478C053869FED" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinanceLeaseLiabilitiesPaymentsDueAbstract_025A180F130F55019578C169D943DF1F" xlink:to="loc_us-gaap_FinanceLeaseLiabilityUndiscountedExcessAmount_607CEDE6DE49583493E478C053869FED" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FinanceLeaseLiability" xlink:label="loc_us-gaap_FinanceLeaseLiability_91F7F6A563735D0AB59FE9DE7F86801D" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinanceLeaseLiabilitiesPaymentsDueAbstract_025A180F130F55019578C169D943DF1F" xlink:to="loc_us-gaap_FinanceLeaseLiability_91F7F6A563735D0AB59FE9DE7F86801D" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/LeasesNarrativeDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LeasesAbstract" xlink:label="loc_us-gaap_LeasesAbstract_63D87F7FCE7F5A06AB030BAE7EC78D0F" xlink:type="locator" />
    <link:loc xlink:href="endp-20190930.xsd#endp_LesseeOperatingLeaseNumberOfRenewalOptions" xlink:label="loc_endp_LesseeOperatingLeaseNumberOfRenewalOptions_B54C3EF87C8E5A9DB61CBD19E21044B7" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_63D87F7FCE7F5A06AB030BAE7EC78D0F" xlink:to="loc_endp_LesseeOperatingLeaseNumberOfRenewalOptions_B54C3EF87C8E5A9DB61CBD19E21044B7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LesseeOperatingLeaseRenewalTerm" xlink:label="loc_us-gaap_LesseeOperatingLeaseRenewalTerm_578DCEEB5A94576A9EE31CABAFF4D969" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_63D87F7FCE7F5A06AB030BAE7EC78D0F" xlink:to="loc_us-gaap_LesseeOperatingLeaseRenewalTerm_578DCEEB5A94576A9EE31CABAFF4D969" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/LeasesTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LeasesAbstract" xlink:label="loc_us-gaap_LeasesAbstract_0D5A033B9D285B2D915FE63DBD94C441" xlink:type="locator" />
    <link:loc xlink:href="endp-20190930.xsd#endp_AssetsAndLiabilitiesLesseeTableTextBlock" xlink:label="loc_endp_AssetsAndLiabilitiesLesseeTableTextBlock_679E1B6F09845AC6982F0DA5A37ABE84" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_0D5A033B9D285B2D915FE63DBD94C441" xlink:to="loc_endp_AssetsAndLiabilitiesLesseeTableTextBlock_679E1B6F09845AC6982F0DA5A37ABE84" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LeaseCostTableTextBlock" xlink:label="loc_us-gaap_LeaseCostTableTextBlock_F3AA09BB156D5AF9ADD9E04EA7FCB22A" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_0D5A033B9D285B2D915FE63DBD94C441" xlink:to="loc_us-gaap_LeaseCostTableTextBlock_F3AA09BB156D5AF9ADD9E04EA7FCB22A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityMaturityTableTextBlock" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityMaturityTableTextBlock_C07B9AC4E3EC585F8FB11FBAF32681DC" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_0D5A033B9D285B2D915FE63DBD94C441" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityMaturityTableTextBlock_C07B9AC4E3EC585F8FB11FBAF32681DC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FinanceLeaseLiabilityMaturityTableTextBlock" xlink:label="loc_us-gaap_FinanceLeaseLiabilityMaturityTableTextBlock_934C0FE830095CEDB40CB0F178B76A26" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_0D5A033B9D285B2D915FE63DBD94C441" xlink:to="loc_us-gaap_FinanceLeaseLiabilityMaturityTableTextBlock_934C0FE830095CEDB40CB0F178B76A26" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfFutureMinimumRentalPaymentsForOperatingLeasesTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfFutureMinimumRentalPaymentsForOperatingLeasesTableTextBlock_ED53DA4163C95417979B1EC401FD80A4" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_0D5A033B9D285B2D915FE63DBD94C441" xlink:to="loc_us-gaap_ScheduleOfFutureMinimumRentalPaymentsForOperatingLeasesTableTextBlock_ED53DA4163C95417979B1EC401FD80A4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfFutureMinimumLeasePaymentsForCapitalLeasesTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfFutureMinimumLeasePaymentsForCapitalLeasesTableTextBlock_E3078F53F0135FDE88F52DC9F867D142" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_0D5A033B9D285B2D915FE63DBD94C441" xlink:to="loc_us-gaap_ScheduleOfFutureMinimumLeasePaymentsForCapitalLeasesTableTextBlock_E3078F53F0135FDE88F52DC9F867D142" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/LeasesWeightedAverageTermLeaseAndDiscountRatesDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LeasesAbstract" xlink:label="loc_us-gaap_LeasesAbstract_77E33292863D55B7A2D89BCB91630A0B" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SalesTypeLeasesNetInvestmentInLeasesAbstract" xlink:label="loc_us-gaap_SalesTypeLeasesNetInvestmentInLeasesAbstract_027A03ACF80A5CEF989AD2AF97190D6A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_77E33292863D55B7A2D89BCB91630A0B" xlink:to="loc_us-gaap_SalesTypeLeasesNetInvestmentInLeasesAbstract_027A03ACF80A5CEF989AD2AF97190D6A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OperatingLeaseWeightedAverageRemainingLeaseTerm1" xlink:label="loc_us-gaap_OperatingLeaseWeightedAverageRemainingLeaseTerm1_2B6851AC61155B9BA7F2C42E73631223" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SalesTypeLeasesNetInvestmentInLeasesAbstract_027A03ACF80A5CEF989AD2AF97190D6A" xlink:to="loc_us-gaap_OperatingLeaseWeightedAverageRemainingLeaseTerm1_2B6851AC61155B9BA7F2C42E73631223" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FinanceLeaseWeightedAverageRemainingLeaseTerm1" xlink:label="loc_us-gaap_FinanceLeaseWeightedAverageRemainingLeaseTerm1_16B6628426C85EC086481DCCF6FB4C79" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SalesTypeLeasesNetInvestmentInLeasesAbstract_027A03ACF80A5CEF989AD2AF97190D6A" xlink:to="loc_us-gaap_FinanceLeaseWeightedAverageRemainingLeaseTerm1_16B6628426C85EC086481DCCF6FB4C79" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DirectFinancingLeaseNetInvestmentInLeasesAbstract" xlink:label="loc_us-gaap_DirectFinancingLeaseNetInvestmentInLeasesAbstract_DD2532482D7A52E393C4EFDCCE30E870" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_77E33292863D55B7A2D89BCB91630A0B" xlink:to="loc_us-gaap_DirectFinancingLeaseNetInvestmentInLeasesAbstract_DD2532482D7A52E393C4EFDCCE30E870" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OperatingLeaseWeightedAverageDiscountRatePercent" xlink:label="loc_us-gaap_OperatingLeaseWeightedAverageDiscountRatePercent_409C7497FFC8570287C52D4495E9C04B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DirectFinancingLeaseNetInvestmentInLeasesAbstract_DD2532482D7A52E393C4EFDCCE30E870" xlink:to="loc_us-gaap_OperatingLeaseWeightedAverageDiscountRatePercent_409C7497FFC8570287C52D4495E9C04B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FinanceLeaseWeightedAverageDiscountRatePercent" xlink:label="loc_us-gaap_FinanceLeaseWeightedAverageDiscountRatePercent_914B44EB70065DBAB32CD1B7BEC3E31D" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DirectFinancingLeaseNetInvestmentInLeasesAbstract_DD2532482D7A52E393C4EFDCCE30E870" xlink:to="loc_us-gaap_FinanceLeaseWeightedAverageDiscountRatePercent_914B44EB70065DBAB32CD1B7BEC3E31D" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/NetLossPerShare" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EarningsPerShareAbstract" xlink:label="loc_us-gaap_EarningsPerShareAbstract_7EC7269B36D653C09DC51FCFB9B9FEF9" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EarningsPerShareTextBlock" xlink:label="loc_us-gaap_EarningsPerShareTextBlock_3B34B9ED9F4E5D2E8E8EC99DD7331D57" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareAbstract_7EC7269B36D653C09DC51FCFB9B9FEF9" xlink:to="loc_us-gaap_EarningsPerShareTextBlock_3B34B9ED9F4E5D2E8E8EC99DD7331D57" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/NetLossPerShareReconciliationOfNumeratorAndDenominatorOfBasicAndDilutedNetLossPerShareDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EarningsPerShareAbstract" xlink:label="loc_us-gaap_EarningsPerShareAbstract_85EE4490C1B52F13C01150DDD87EBB59" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EarningsPerShareReconciliationAbstract" xlink:label="loc_us-gaap_EarningsPerShareReconciliationAbstract_38FE5FD8C6A013AB179B50DDD87F533D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareAbstract_85EE4490C1B52F13C01150DDD87EBB59" xlink:to="loc_us-gaap_EarningsPerShareReconciliationAbstract_38FE5FD8C6A013AB179B50DDD87F533D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeLossFromContinuingOperations" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperations_8D53D092332D1760DECC50DDD87F09F1" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareReconciliationAbstract_38FE5FD8C6A013AB179B50DDD87F533D" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperations_8D53D092332D1760DECC50DDD87F09F1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxAttributableToReportingEntity" xlink:label="loc_us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxAttributableToReportingEntity_33230D8D1004AE5612D750DDD87F8530" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareReconciliationAbstract_38FE5FD8C6A013AB179B50DDD87F533D" xlink:to="loc_us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxAttributableToReportingEntity_33230D8D1004AE5612D750DDD87F8530" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_NetIncomeLoss" xlink:label="loc_us-gaap_NetIncomeLoss_BFC163028934AB3EF22D50DDD87FC319" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareReconciliationAbstract_38FE5FD8C6A013AB179B50DDD87F533D" xlink:to="loc_us-gaap_NetIncomeLoss_BFC163028934AB3EF22D50DDD87FC319" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingDilutedDisclosureItemsAbstract" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingDilutedDisclosureItemsAbstract_AE3DDC7EC64601F80FC450DDD88055EC" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareAbstract_85EE4490C1B52F13C01150DDD87EBB59" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingDilutedDisclosureItemsAbstract_AE3DDC7EC64601F80FC450DDD88055EC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingBasic" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_9A0865B9C22D2681927950DDD8805AA1" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingDilutedDisclosureItemsAbstract_AE3DDC7EC64601F80FC450DDD88055EC" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_9A0865B9C22D2681927950DDD8805AA1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements" xlink:label="loc_us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements_BB48B68BDA6430678F9450DDD880B3D9" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingDilutedDisclosureItemsAbstract_AE3DDC7EC64601F80FC450DDD88055EC" xlink:to="loc_us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements_BB48B68BDA6430678F9450DDD880B3D9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding" xlink:label="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_73983AA5DD98B1C852A450DDD880FEA6" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingDilutedDisclosureItemsAbstract_AE3DDC7EC64601F80FC450DDD88055EC" xlink:to="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_73983AA5DD98B1C852A450DDD880FEA6" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/NetLossPerShareTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EarningsPerShareAbstract" xlink:label="loc_us-gaap_EarningsPerShareAbstract_E33FCAD481D55713AA01B950750EA24F" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock_021E96E5AB425218B5A602FE788E78E2" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareAbstract_E33FCAD481D55713AA01B950750EA24F" xlink:to="loc_us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock_021E96E5AB425218B5A602FE788E78E2" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/OtherComprehensiveIncomeLoss" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EquityAbstract" xlink:label="loc_us-gaap_EquityAbstract_91EEAC272B1F5A0F98570FF9B5E0A701" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ComprehensiveIncomeNoteTextBlock" xlink:label="loc_us-gaap_ComprehensiveIncomeNoteTextBlock_15209F8B99F45C35AE9FB4630CFDD2F1" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_91EEAC272B1F5A0F98570FF9B5E0A701" xlink:to="loc_us-gaap_ComprehensiveIncomeNoteTextBlock_15209F8B99F45C35AE9FB4630CFDD2F1" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/OtherComprehensiveLossNarrativeDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EquityAbstract" xlink:label="loc_us-gaap_EquityAbstract_CA5ACBD48EF553B69DB595A8C05F1884" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossTaxPortionAttributableToParent1" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossTaxPortionAttributableToParent1_CE6A7AF3ADEA5A78AB1608F36E7E8121" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_CA5ACBD48EF553B69DB595A8C05F1884" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossTaxPortionAttributableToParent1_CE6A7AF3ADEA5A78AB1608F36E7E8121" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/OtherExpenseIncomeNet" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OtherIncomeAbstract" xlink:label="loc_us-gaap_OtherIncomeAbstract_5FE89888C3621D6CDFA969A2CC7453EC" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OtherIncomeAndOtherExpenseDisclosureTextBlock" xlink:label="loc_us-gaap_OtherIncomeAndOtherExpenseDisclosureTextBlock_834E71C00487DD0CA7DA69A2CC742AC9" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherIncomeAbstract_5FE89888C3621D6CDFA969A2CC7453EC" xlink:to="loc_us-gaap_OtherIncomeAndOtherExpenseDisclosureTextBlock_834E71C00487DD0CA7DA69A2CC742AC9" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/OtherExpenseIncomeNetDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OtherIncomeAbstract" xlink:label="loc_us-gaap_OtherIncomeAbstract_2C499706334134E1FBD7245931DB97BD" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_GainLossOnDispositionOfAssets1" xlink:label="loc_us-gaap_GainLossOnDispositionOfAssets1_0710E58A6F0AF98472EF245931DB5EA3" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherIncomeAbstract_2C499706334134E1FBD7245931DB97BD" xlink:to="loc_us-gaap_GainLossOnDispositionOfAssets1_0710E58A6F0AF98472EF245931DB5EA3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ForeignCurrencyTransactionGainLossBeforeTax" xlink:label="loc_us-gaap_ForeignCurrencyTransactionGainLossBeforeTax_DAABC98AEB80647B97B6245931E0CDB7" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherIncomeAbstract_2C499706334134E1FBD7245931DB97BD" xlink:to="loc_us-gaap_ForeignCurrencyTransactionGainLossBeforeTax_DAABC98AEB80647B97B6245931E0CDB7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeLossFromEquityMethodInvestments" xlink:label="loc_us-gaap_IncomeLossFromEquityMethodInvestments_EF744CDD920727D7EB56245931E0BCCC" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherIncomeAbstract_2C499706334134E1FBD7245931DB97BD" xlink:to="loc_us-gaap_IncomeLossFromEquityMethodInvestments_EF744CDD920727D7EB56245931E0BCCC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OtherNonoperatingIncomeExpense" xlink:label="loc_us-gaap_OtherNonoperatingIncomeExpense_AB8D4043D7DEED528012245931E19418" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherIncomeAbstract_2C499706334134E1FBD7245931DB97BD" xlink:to="loc_us-gaap_OtherNonoperatingIncomeExpense_AB8D4043D7DEED528012245931E19418" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_NonoperatingIncomeExpense" xlink:label="loc_us-gaap_NonoperatingIncomeExpense_D4900A6A80C242ABB1CA245931E10689" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2009/role/negatedTotalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherIncomeAbstract_2C499706334134E1FBD7245931DB97BD" xlink:to="loc_us-gaap_NonoperatingIncomeExpense_D4900A6A80C242ABB1CA245931E10689" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfRestructuringAndRelatedCostsTable" xlink:label="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_7D1AF25F63EB090E6E6F245931E199A9" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherIncomeAbstract_2C499706334134E1FBD7245931DB97BD" xlink:to="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_7D1AF25F63EB090E6E6F245931E199A9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestructuringCostAndReserveAxis" xlink:label="loc_us-gaap_RestructuringCostAndReserveAxis_92D82A5A3EE0B74AAB13245931E18688" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_7D1AF25F63EB090E6E6F245931E199A9" xlink:to="loc_us-gaap_RestructuringCostAndReserveAxis_92D82A5A3EE0B74AAB13245931E18688" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_TypeOfRestructuringDomain" xlink:label="loc_us-gaap_TypeOfRestructuringDomain_987BAC613537D6E9B39F245931E152AB" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringCostAndReserveAxis_92D82A5A3EE0B74AAB13245931E18688" xlink:to="loc_us-gaap_TypeOfRestructuringDomain_987BAC613537D6E9B39F245931E152AB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ContractTerminationMember" xlink:label="loc_us-gaap_ContractTerminationMember_D2F0347E9B168C541773245931E2B575" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfRestructuringDomain_987BAC613537D6E9B39F245931E152AB" xlink:to="loc_us-gaap_ContractTerminationMember_D2F0347E9B168C541773245931E2B575" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestructuringCostAndReserveLineItems" xlink:label="loc_us-gaap_RestructuringCostAndReserveLineItems_882556E0AD303EE8720E245931E20DA3" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_7D1AF25F63EB090E6E6F245931E199A9" xlink:to="loc_us-gaap_RestructuringCostAndReserveLineItems_882556E0AD303EE8720E245931E20DA3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestructuringCharges" xlink:label="loc_us-gaap_RestructuringCharges_6DDB59D790A99AEF6261245931E26BD3" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringCostAndReserveLineItems_882556E0AD303EE8720E245931E20DA3" xlink:to="loc_us-gaap_RestructuringCharges_6DDB59D790A99AEF6261245931E26BD3" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/OtherExpenseIncomeNetTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OtherIncomeAbstract" xlink:label="loc_us-gaap_OtherIncomeAbstract_5B465EC270F5A1E8B8D069A2CC72A36A" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfOtherNonoperatingIncomeByComponentTextBlock" xlink:label="loc_us-gaap_ScheduleOfOtherNonoperatingIncomeByComponentTextBlock_8141E146617234680AF369A2CC731401" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherIncomeAbstract_5B465EC270F5A1E8B8D069A2CC72A36A" xlink:to="loc_us-gaap_ScheduleOfOtherNonoperatingIncomeByComponentTextBlock_8141E146617234680AF369A2CC731401" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/Restructuring" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestructuringAndRelatedActivitiesAbstract" xlink:label="loc_us-gaap_RestructuringAndRelatedActivitiesAbstract_8E43D4E688E85D5EA1A367E3F3D38767" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestructuringAndRelatedActivitiesDisclosureTextBlock" xlink:label="loc_us-gaap_RestructuringAndRelatedActivitiesDisclosureTextBlock_AA7FA342E99D5CCC8FEEF72B403CE10C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringAndRelatedActivitiesAbstract_8E43D4E688E85D5EA1A367E3F3D38767" xlink:to="loc_us-gaap_RestructuringAndRelatedActivitiesDisclosureTextBlock_AA7FA342E99D5CCC8FEEF72B403CE10C" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/Restructuring2017RestructuringInitiativesNarrativeDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestructuringAndRelatedActivitiesAbstract" xlink:label="loc_us-gaap_RestructuringAndRelatedActivitiesAbstract_F429AF2E9F69753523E1FFA7E859AFA9" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfRestructuringAndRelatedCostsTable" xlink:label="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_BF172F8C944FEEBF5622FFA7E85996DE" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringAndRelatedActivitiesAbstract_F429AF2E9F69753523E1FFA7E859AFA9" xlink:to="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_BF172F8C944FEEBF5622FFA7E85996DE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis" xlink:label="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_C554EB5C65EA40BCB3A6FFA7E8595D5A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_BF172F8C944FEEBF5622FFA7E85996DE" xlink:to="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_C554EB5C65EA40BCB3A6FFA7E8595D5A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain" xlink:label="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_9E8CF288CE94BA32EC9CFFA7E8594A7E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_C554EB5C65EA40BCB3A6FFA7E8595D5A" xlink:to="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_9E8CF288CE94BA32EC9CFFA7E8594A7E" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_HuntsvilleAlabamaManufacturingandDistributingFacilityMember" xlink:label="loc_endp_HuntsvilleAlabamaManufacturingandDistributingFacilityMember_781FF0CD05A06C03A798FFA7E859DC01" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_9E8CF288CE94BA32EC9CFFA7E8594A7E" xlink:to="loc_endp_HuntsvilleAlabamaManufacturingandDistributingFacilityMember_781FF0CD05A06C03A798FFA7E859DC01" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DisposalGroupClassificationAxis" xlink:label="loc_us-gaap_DisposalGroupClassificationAxis_2BB8A020C6F538CD85DBFFA7E85917E1" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_BF172F8C944FEEBF5622FFA7E85996DE" xlink:to="loc_us-gaap_DisposalGroupClassificationAxis_2BB8A020C6F538CD85DBFFA7E85917E1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DisposalGroupClassificationDomain" xlink:label="loc_us-gaap_DisposalGroupClassificationDomain_928BB13C72A510BCFA31FFA7E8596E08" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisposalGroupClassificationAxis_2BB8A020C6F538CD85DBFFA7E85917E1" xlink:to="loc_us-gaap_DisposalGroupClassificationDomain_928BB13C72A510BCFA31FFA7E8596E08" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DisposalGroupDisposedOfBySaleNotDiscontinuedOperationsMember" xlink:label="loc_us-gaap_DisposalGroupDisposedOfBySaleNotDiscontinuedOperationsMember_55887D3B344DA8AA9693FFA7E859A63E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisposalGroupClassificationDomain_928BB13C72A510BCFA31FFA7E8596E08" xlink:to="loc_us-gaap_DisposalGroupDisposedOfBySaleNotDiscontinuedOperationsMember_55887D3B344DA8AA9693FFA7E859A63E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestructuringPlanAxis" xlink:label="loc_us-gaap_RestructuringPlanAxis_F4F538C98385F68219ECFFA7E859404C" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_BF172F8C944FEEBF5622FFA7E85996DE" xlink:to="loc_us-gaap_RestructuringPlanAxis_F4F538C98385F68219ECFFA7E859404C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestructuringPlanDomain" xlink:label="loc_us-gaap_RestructuringPlanDomain_B33DA5CDFF56111C0D0EFFA7E8599DDC" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringPlanAxis_F4F538C98385F68219ECFFA7E859404C" xlink:to="loc_us-gaap_RestructuringPlanDomain_B33DA5CDFF56111C0D0EFFA7E8599DDC" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_USGenericPharmaceuticalsRestructuring2017Member" xlink:label="loc_endp_USGenericPharmaceuticalsRestructuring2017Member_55FBAAD9830034BF66F3FFA7E8592080" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringPlanDomain_B33DA5CDFF56111C0D0EFFA7E8599DDC" xlink:to="loc_endp_USGenericPharmaceuticalsRestructuring2017Member_55FBAAD9830034BF66F3FFA7E8592080" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_EmployeeSeparationRetentionandOtherBenefitRelatedCostsMember" xlink:label="loc_endp_EmployeeSeparationRetentionandOtherBenefitRelatedCostsMember_FB2E4E1E26A8912005CEFFA7E859E368" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringPlanDomain_B33DA5CDFF56111C0D0EFFA7E8599DDC" xlink:to="loc_endp_EmployeeSeparationRetentionandOtherBenefitRelatedCostsMember_FB2E4E1E26A8912005CEFFA7E859E368" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestructuringCostAndReserveAxis" xlink:label="loc_us-gaap_RestructuringCostAndReserveAxis_EDD35105C5AED7B9EEB4FFA7E8596776" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_BF172F8C944FEEBF5622FFA7E85996DE" xlink:to="loc_us-gaap_RestructuringCostAndReserveAxis_EDD35105C5AED7B9EEB4FFA7E8596776" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_TypeOfRestructuringDomain" xlink:label="loc_us-gaap_TypeOfRestructuringDomain_CF9E3170B71A7F0211FBFFA7E86296AD" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringCostAndReserveAxis_EDD35105C5AED7B9EEB4FFA7E8596776" xlink:to="loc_us-gaap_TypeOfRestructuringDomain_CF9E3170B71A7F0211FBFFA7E86296AD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FacilityClosingMember" xlink:label="loc_us-gaap_FacilityClosingMember_BB206BCD3BDF059F08B1FFA7E8624BFB" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfRestructuringDomain_CF9E3170B71A7F0211FBFFA7E86296AD" xlink:to="loc_us-gaap_FacilityClosingMember_BB206BCD3BDF059F08B1FFA7E8624BFB" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_AcceleratedDepreciationMember" xlink:label="loc_endp_AcceleratedDepreciationMember_A164D9674F2C61CD1931FFA7E862B296" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfRestructuringDomain_CF9E3170B71A7F0211FBFFA7E86296AD" xlink:to="loc_endp_AcceleratedDepreciationMember_A164D9674F2C61CD1931FFA7E862B296" xlink:type="arc" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfRestructuringDomain_CF9E3170B71A7F0211FBFFA7E86296AD" xlink:to="loc_endp_EmployeeSeparationRetentionandOtherBenefitRelatedCostsMember_FB2E4E1E26A8912005CEFFA7E859E368" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OtherRestructuringMember" xlink:label="loc_us-gaap_OtherRestructuringMember_D413F38281005E8B2F3FFFA7E8629279" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfRestructuringDomain_CF9E3170B71A7F0211FBFFA7E86296AD" xlink:to="loc_us-gaap_OtherRestructuringMember_D413F38281005E8B2F3FFFA7E8629279" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_PropertyPlantandEquipmentImpairmentChargesMember" xlink:label="loc_endp_PropertyPlantandEquipmentImpairmentChargesMember_D2325628A40BE8BBEAE6FFA7E8621835" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfRestructuringDomain_CF9E3170B71A7F0211FBFFA7E86296AD" xlink:to="loc_endp_PropertyPlantandEquipmentImpairmentChargesMember_D2325628A40BE8BBEAE6FFA7E8621835" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StatementBusinessSegmentsAxis" xlink:label="loc_us-gaap_StatementBusinessSegmentsAxis_24DFD50FDF4B0FDB6BD2FFA7E862365C" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_BF172F8C944FEEBF5622FFA7E85996DE" xlink:to="loc_us-gaap_StatementBusinessSegmentsAxis_24DFD50FDF4B0FDB6BD2FFA7E862365C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SegmentDomain" xlink:label="loc_us-gaap_SegmentDomain_40D43F03BB6B8A471D2EFFA7E862FDE4" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_24DFD50FDF4B0FDB6BD2FFA7E862365C" xlink:to="loc_us-gaap_SegmentDomain_40D43F03BB6B8A471D2EFFA7E862FDE4" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_GenericPharmaceuticalsMember" xlink:label="loc_endp_GenericPharmaceuticalsMember_5755EB832B4B49C9E75EFFA7E86200F3" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_40D43F03BB6B8A471D2EFFA7E862FDE4" xlink:to="loc_endp_GenericPharmaceuticalsMember_5755EB832B4B49C9E75EFFA7E86200F3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestructuringCostAndReserveLineItems" xlink:label="loc_us-gaap_RestructuringCostAndReserveLineItems_E5C6C125C31B11125F2BFFA7E862BA2A" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_BF172F8C944FEEBF5622FFA7E85996DE" xlink:to="loc_us-gaap_RestructuringCostAndReserveLineItems_E5C6C125C31B11125F2BFFA7E862BA2A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ProceedsFromSaleOfPropertyPlantAndEquipment" xlink:label="loc_us-gaap_ProceedsFromSaleOfPropertyPlantAndEquipment_753AE4ACA96A0AED6930FFA7E8629F0E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringCostAndReserveLineItems_E5C6C125C31B11125F2BFFA7E862BA2A" xlink:to="loc_us-gaap_ProceedsFromSaleOfPropertyPlantAndEquipment_753AE4ACA96A0AED6930FFA7E8629F0E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DisposalGroupNotDiscontinuedOperationGainLossOnDisposal" xlink:label="loc_us-gaap_DisposalGroupNotDiscontinuedOperationGainLossOnDisposal_A039E62B1A4AD1E4959BFFA7E862B9D0" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringCostAndReserveLineItems_E5C6C125C31B11125F2BFFA7E862BA2A" xlink:to="loc_us-gaap_DisposalGroupNotDiscontinuedOperationGainLossOnDisposal_A039E62B1A4AD1E4959BFFA7E862B9D0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestructuringCharges" xlink:label="loc_us-gaap_RestructuringCharges_E9E934B8A406C99C4AEFFFA7E862C2D1" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringCostAndReserveLineItems_E5C6C125C31B11125F2BFFA7E862BA2A" xlink:to="loc_us-gaap_RestructuringCharges_E9E934B8A406C99C4AEFFFA7E862C2D1" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/RestructuringJanuary2018RestructuringInitiativeNarrativeDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestructuringAndRelatedActivitiesAbstract" xlink:label="loc_us-gaap_RestructuringAndRelatedActivitiesAbstract_EA81CFE53FAB5B8EE71D69A2D03F7BD7" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfRestructuringAndRelatedCostsTable" xlink:label="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_F4FD9C70F72AAAECE27069A2D03F98CE" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringAndRelatedActivitiesAbstract_EA81CFE53FAB5B8EE71D69A2D03F7BD7" xlink:to="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_F4FD9C70F72AAAECE27069A2D03F98CE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_ConsolidationItemsAxis" xlink:label="loc_srt_ConsolidationItemsAxis_A1FA3D08538EEC745B2169A2D03FC293" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_F4FD9C70F72AAAECE27069A2D03F98CE" xlink:to="loc_srt_ConsolidationItemsAxis_A1FA3D08538EEC745B2169A2D03FC293" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_ConsolidationItemsDomain" xlink:label="loc_srt_ConsolidationItemsDomain_FF7236B38F2FDCCC1B5569A2D03F9AEE" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ConsolidationItemsAxis_A1FA3D08538EEC745B2169A2D03FC293" xlink:to="loc_srt_ConsolidationItemsDomain_FF7236B38F2FDCCC1B5569A2D03F9AEE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OperatingSegmentsMember" xlink:label="loc_us-gaap_OperatingSegmentsMember_A87FA2B3F0D0492F11BD69A2D03FD26B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ConsolidationItemsDomain_FF7236B38F2FDCCC1B5569A2D03F9AEE" xlink:to="loc_us-gaap_OperatingSegmentsMember_A87FA2B3F0D0492F11BD69A2D03FD26B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_MaterialReconcilingItemsMember" xlink:label="loc_us-gaap_MaterialReconcilingItemsMember_672F038C0768D7427EEA69A2D03F6C10" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ConsolidationItemsDomain_FF7236B38F2FDCCC1B5569A2D03F9AEE" xlink:to="loc_us-gaap_MaterialReconcilingItemsMember_672F038C0768D7427EEA69A2D03F6C10" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StatementBusinessSegmentsAxis" xlink:label="loc_us-gaap_StatementBusinessSegmentsAxis_6C64F76E9D7C8E7B5AD069A2D03F4077" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_F4FD9C70F72AAAECE27069A2D03F98CE" xlink:to="loc_us-gaap_StatementBusinessSegmentsAxis_6C64F76E9D7C8E7B5AD069A2D03F4077" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SegmentDomain" xlink:label="loc_us-gaap_SegmentDomain_470F024BE0A56520F13D69A2D03F1C34" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_6C64F76E9D7C8E7B5AD069A2D03F4077" xlink:to="loc_us-gaap_SegmentDomain_470F024BE0A56520F13D69A2D03F1C34" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_GenericPharmaceuticalsMember" xlink:label="loc_endp_GenericPharmaceuticalsMember_013D9E5001897504ECD969A2D03FD3A9" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_470F024BE0A56520F13D69A2D03F1C34" xlink:to="loc_endp_GenericPharmaceuticalsMember_013D9E5001897504ECD969A2D03FD3A9" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_BrandedSterileInjectablesMember" xlink:label="loc_endp_BrandedSterileInjectablesMember_B8AB4115CE371687F40C69A2D03FD0E6" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_470F024BE0A56520F13D69A2D03F1C34" xlink:to="loc_endp_BrandedSterileInjectablesMember_B8AB4115CE371687F40C69A2D03FD0E6" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_InternationalPharmaceuticalsMember" xlink:label="loc_endp_InternationalPharmaceuticalsMember_C4589746E19CF90CECF869A2D03FCD6E" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_470F024BE0A56520F13D69A2D03F1C34" xlink:to="loc_endp_InternationalPharmaceuticalsMember_C4589746E19CF90CECF869A2D03FCD6E" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_BrandedSpecialtyandEstablishedPharmaceuticalsMember" xlink:label="loc_endp_BrandedSpecialtyandEstablishedPharmaceuticalsMember_37282B331BC130FC76C569A2D03F3CE4" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_470F024BE0A56520F13D69A2D03F1C34" xlink:to="loc_endp_BrandedSpecialtyandEstablishedPharmaceuticalsMember_37282B331BC130FC76C569A2D03F3CE4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestructuringCostAndReserveAxis" xlink:label="loc_us-gaap_RestructuringCostAndReserveAxis_086656326599025A9DAB69A2D03F26D8" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_F4FD9C70F72AAAECE27069A2D03F98CE" xlink:to="loc_us-gaap_RestructuringCostAndReserveAxis_086656326599025A9DAB69A2D03F26D8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_TypeOfRestructuringDomain" xlink:label="loc_us-gaap_TypeOfRestructuringDomain_C01DFDAA59EAD4C19EFF69A2D03FADE5" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringCostAndReserveAxis_086656326599025A9DAB69A2D03F26D8" xlink:to="loc_us-gaap_TypeOfRestructuringDomain_C01DFDAA59EAD4C19EFF69A2D03FADE5" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_EmployeeSeparationRetentionandOtherBenefitRelatedCostsMember" xlink:label="loc_endp_EmployeeSeparationRetentionandOtherBenefitRelatedCostsMember_ABFAEE367F965F4C68E269A2D03FC071" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfRestructuringDomain_C01DFDAA59EAD4C19EFF69A2D03FADE5" xlink:to="loc_endp_EmployeeSeparationRetentionandOtherBenefitRelatedCostsMember_ABFAEE367F965F4C68E269A2D03FC071" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OtherRestructuringMember" xlink:label="loc_us-gaap_OtherRestructuringMember_7D83DFEAA95DDFCA569469A2D03F43C8" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfRestructuringDomain_C01DFDAA59EAD4C19EFF69A2D03FADE5" xlink:to="loc_us-gaap_OtherRestructuringMember_7D83DFEAA95DDFCA569469A2D03F43C8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestructuringPlanAxis" xlink:label="loc_us-gaap_RestructuringPlanAxis_84FA87F8CC0B5887AF2869A2D03F89BE" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_F4FD9C70F72AAAECE27069A2D03F98CE" xlink:to="loc_us-gaap_RestructuringPlanAxis_84FA87F8CC0B5887AF2869A2D03F89BE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestructuringPlanDomain" xlink:label="loc_us-gaap_RestructuringPlanDomain_D738759FAE89B550997D69A2D03FC464" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringPlanAxis_84FA87F8CC0B5887AF2869A2D03F89BE" xlink:to="loc_us-gaap_RestructuringPlanDomain_D738759FAE89B550997D69A2D03FC464" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_January2018RestructuringMember" xlink:label="loc_endp_January2018RestructuringMember_560E9B3F2C57FE13287569A2D03F2C74" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringPlanDomain_D738759FAE89B550997D69A2D03FC464" xlink:to="loc_endp_January2018RestructuringMember_560E9B3F2C57FE13287569A2D03F2C74" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestructuringCostAndReserveLineItems" xlink:label="loc_us-gaap_RestructuringCostAndReserveLineItems_C9D0826F928745FADC0E69A2D03FF7DD" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_F4FD9C70F72AAAECE27069A2D03F98CE" xlink:to="loc_us-gaap_RestructuringCostAndReserveLineItems_C9D0826F928745FADC0E69A2D03FF7DD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestructuringCharges" xlink:label="loc_us-gaap_RestructuringCharges_2077C108A54EDAF9B6A369A2D03FC436" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringCostAndReserveLineItems_C9D0826F928745FADC0E69A2D03FF7DD" xlink:to="loc_us-gaap_RestructuringCharges_2077C108A54EDAF9B6A369A2D03FC436" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestructuringReserve" xlink:label="loc_us-gaap_RestructuringReserve_EC4AED0369093D0597AB69A2D03F820F" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringCostAndReserveLineItems_C9D0826F928745FADC0E69A2D03FF7DD" xlink:to="loc_us-gaap_RestructuringReserve_EC4AED0369093D0597AB69A2D03F820F" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/RestructuringScheduleOfRestructuringRollForwardDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestructuringAndRelatedActivitiesAbstract" xlink:label="loc_us-gaap_RestructuringAndRelatedActivitiesAbstract_8ACAB832C625561091B4D2E2CF41F1F0" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfRestructuringAndRelatedCostsTable" xlink:label="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_4DF9A2EE003859A8AAFAD4B6DAB03E57" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringAndRelatedActivitiesAbstract_8ACAB832C625561091B4D2E2CF41F1F0" xlink:to="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_4DF9A2EE003859A8AAFAD4B6DAB03E57" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestructuringPlanAxis" xlink:label="loc_us-gaap_RestructuringPlanAxis_28AC7831EEA55222A0F2981A774449F8" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_4DF9A2EE003859A8AAFAD4B6DAB03E57" xlink:to="loc_us-gaap_RestructuringPlanAxis_28AC7831EEA55222A0F2981A774449F8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestructuringPlanDomain" xlink:label="loc_us-gaap_RestructuringPlanDomain_4C58C69ED2C457DAB93EA52E793004D2" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringPlanAxis_28AC7831EEA55222A0F2981A774449F8" xlink:to="loc_us-gaap_RestructuringPlanDomain_4C58C69ED2C457DAB93EA52E793004D2" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_USGenericPharmaceuticalsRestructuring2017Member" xlink:label="loc_endp_USGenericPharmaceuticalsRestructuring2017Member_993D43691B8A5C2DBE9C690AA4E607D8" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringPlanDomain_4C58C69ED2C457DAB93EA52E793004D2" xlink:to="loc_endp_USGenericPharmaceuticalsRestructuring2017Member_993D43691B8A5C2DBE9C690AA4E607D8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestructuringCostAndReserveAxis" xlink:label="loc_us-gaap_RestructuringCostAndReserveAxis_F783A041D7D95CE9B5A20BF984B22125" xlink:type="locator" />
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_4DF9A2EE003859A8AAFAD4B6DAB03E57" xlink:to="loc_us-gaap_RestructuringCostAndReserveAxis_F783A041D7D95CE9B5A20BF984B22125" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_TypeOfRestructuringDomain" xlink:label="loc_us-gaap_TypeOfRestructuringDomain_0BD1C8DED7CD54E29641A35E17398428" xlink:type="locator" />
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringCostAndReserveAxis_F783A041D7D95CE9B5A20BF984B22125" xlink:to="loc_us-gaap_TypeOfRestructuringDomain_0BD1C8DED7CD54E29641A35E17398428" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_EmployeeSeverenceandOtherBenefitRelatedCostsMember" xlink:label="loc_endp_EmployeeSeverenceandOtherBenefitRelatedCostsMember_0EF762CB395A57BFA688D6BE33ADE770" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfRestructuringDomain_0BD1C8DED7CD54E29641A35E17398428" xlink:to="loc_endp_EmployeeSeverenceandOtherBenefitRelatedCostsMember_0EF762CB395A57BFA688D6BE33ADE770" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OtherRestructuringMember" xlink:label="loc_us-gaap_OtherRestructuringMember_EDEAF99DA8F05521B17D2AF3485404DF" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/netLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfRestructuringDomain_0BD1C8DED7CD54E29641A35E17398428" xlink:to="loc_us-gaap_OtherRestructuringMember_EDEAF99DA8F05521B17D2AF3485404DF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestructuringCostAndReserveLineItems" xlink:label="loc_us-gaap_RestructuringCostAndReserveLineItems_9659679006585C7797AF183A96EA918F" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_4DF9A2EE003859A8AAFAD4B6DAB03E57" xlink:to="loc_us-gaap_RestructuringCostAndReserveLineItems_9659679006585C7797AF183A96EA918F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestructuringReserveRollForward" xlink:label="loc_us-gaap_RestructuringReserveRollForward_32799FA56B665D6990D06502D2999825" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringCostAndReserveLineItems_9659679006585C7797AF183A96EA918F" xlink:to="loc_us-gaap_RestructuringReserveRollForward_32799FA56B665D6990D06502D2999825" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestructuringReserve" xlink:label="loc_us-gaap_RestructuringReserve_7D63C6F099975E48A2FCFC72C6D7614A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringReserveRollForward_32799FA56B665D6990D06502D2999825" xlink:to="loc_us-gaap_RestructuringReserve_7D63C6F099975E48A2FCFC72C6D7614A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_PaymentsForRestructuring" xlink:label="loc_us-gaap_PaymentsForRestructuring_D373C999545F56618A239CD981B9DB0D" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringReserveRollForward_32799FA56B665D6990D06502D2999825" xlink:to="loc_us-gaap_PaymentsForRestructuring_D373C999545F56618A239CD981B9DB0D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestructuringReserve" xlink:label="loc_us-gaap_RestructuringReserve_4027F074B2CD5A649CC56498E22E3C79" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringReserveRollForward_32799FA56B665D6990D06502D2999825" xlink:to="loc_us-gaap_RestructuringReserve_4027F074B2CD5A649CC56498E22E3C79" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/RestructuringTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestructuringAndRelatedActivitiesAbstract" xlink:label="loc_us-gaap_RestructuringAndRelatedActivitiesAbstract_06F8A078C71A51BC9DC1728F42E48EAC" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfRestructuringReserveByTypeOfCostTextBlock" xlink:label="loc_us-gaap_ScheduleOfRestructuringReserveByTypeOfCostTextBlock_BD5D9C026C06545D89D97B1621038577" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringAndRelatedActivitiesAbstract_06F8A078C71A51BC9DC1728F42E48EAC" xlink:to="loc_us-gaap_ScheduleOfRestructuringReserveByTypeOfCostTextBlock_BD5D9C026C06545D89D97B1621038577" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/SegmentResults" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SegmentReportingAbstract" xlink:label="loc_us-gaap_SegmentReportingAbstract_BCF83346B7BE5662A5ED606AD0DFA0F6" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SegmentReportingDisclosureTextBlock" xlink:label="loc_us-gaap_SegmentReportingDisclosureTextBlock_C712BD4C7DEB52958ACF1FB067682AC1" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingAbstract_BCF83346B7BE5662A5ED606AD0DFA0F6" xlink:to="loc_us-gaap_SegmentReportingDisclosureTextBlock_C712BD4C7DEB52958ACF1FB067682AC1" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/SegmentResultsScheduleOfDisaggregationOfRevenuesDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SegmentReportingAbstract" xlink:label="loc_us-gaap_SegmentReportingAbstract_E6F8DCB4D3A85DDDABE6DA96C4C69202" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DisaggregationOfRevenueTable" xlink:label="loc_us-gaap_DisaggregationOfRevenueTable_F76C987A2A3B8DEE01A9DA96C4C6A706" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingAbstract_E6F8DCB4D3A85DDDABE6DA96C4C69202" xlink:to="loc_us-gaap_DisaggregationOfRevenueTable_F76C987A2A3B8DEE01A9DA96C4C6A706" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_ProductOrServiceAxis" xlink:label="loc_srt_ProductOrServiceAxis_0BD641645F988012D987DA96C4C67CC0" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisaggregationOfRevenueTable_F76C987A2A3B8DEE01A9DA96C4C6A706" xlink:to="loc_srt_ProductOrServiceAxis_0BD641645F988012D987DA96C4C67CC0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_ProductsAndServicesDomain" xlink:label="loc_srt_ProductsAndServicesDomain_2AA86EBDAAA889E6CAA3DA96C4C6EA59" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductOrServiceAxis_0BD641645F988012D987DA96C4C67CC0" xlink:to="loc_srt_ProductsAndServicesDomain_2AA86EBDAAA889E6CAA3DA96C4C6EA59" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_XiaflexMember" xlink:label="loc_endp_XiaflexMember_77CD2781B2055A6CEC6ADA96C4C6C30F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_2AA86EBDAAA889E6CAA3DA96C4C6EA59" xlink:to="loc_endp_XiaflexMember_77CD2781B2055A6CEC6ADA96C4C6C30F" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_SUPPRELINLAMember" xlink:label="loc_endp_SUPPRELINLAMember_306C4495EE991470E7E5DA96C4C6D5AD" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_2AA86EBDAAA889E6CAA3DA96C4C6EA59" xlink:to="loc_endp_SUPPRELINLAMember_306C4495EE991470E7E5DA96C4C6D5AD" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_OtherSpecialtyProductsMember" xlink:label="loc_endp_OtherSpecialtyProductsMember_DD3330EE532E8483D868DA96C4C6741A" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_2AA86EBDAAA889E6CAA3DA96C4C6EA59" xlink:to="loc_endp_OtherSpecialtyProductsMember_DD3330EE532E8483D868DA96C4C6741A" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_TotalSpecialtyProductsMember" xlink:label="loc_endp_TotalSpecialtyProductsMember_2BCAC561FFD8741F0130DA96C4C63941" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_2AA86EBDAAA889E6CAA3DA96C4C6EA59" xlink:to="loc_endp_TotalSpecialtyProductsMember_2BCAC561FFD8741F0130DA96C4C63941" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_PERCOCETMember" xlink:label="loc_endp_PERCOCETMember_475353D0E52AA32C8827DA96C4C670E7" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_2AA86EBDAAA889E6CAA3DA96C4C6EA59" xlink:to="loc_endp_PERCOCETMember_475353D0E52AA32C8827DA96C4C670E7" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_TestopelMember" xlink:label="loc_endp_TestopelMember_5626CEA5B9ED7FCD54A8DA96C4C64D33" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_2AA86EBDAAA889E6CAA3DA96C4C6EA59" xlink:to="loc_endp_TestopelMember_5626CEA5B9ED7FCD54A8DA96C4C64D33" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_OtherEstablishedProductsMember" xlink:label="loc_endp_OtherEstablishedProductsMember_96822DFBF9CF312E6731DA96C4C60616" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_2AA86EBDAAA889E6CAA3DA96C4C6EA59" xlink:to="loc_endp_OtherEstablishedProductsMember_96822DFBF9CF312E6731DA96C4C60616" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_EstablishedProductsMember" xlink:label="loc_endp_EstablishedProductsMember_E022D14E12464F34134BDA96C4C66186" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_2AA86EBDAAA889E6CAA3DA96C4C6EA59" xlink:to="loc_endp_EstablishedProductsMember_E022D14E12464F34134BDA96C4C66186" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_VasostrictMember" xlink:label="loc_endp_VasostrictMember_BCB215E70F8A62137526DA96C4C6F291" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_2AA86EBDAAA889E6CAA3DA96C4C6EA59" xlink:to="loc_endp_VasostrictMember_BCB215E70F8A62137526DA96C4C6F291" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_AdrenalinMember" xlink:label="loc_endp_AdrenalinMember_390616CC4E5C6FCAAD1DDA96C4C6F729" xlink:type="locator" />
    <link:presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_2AA86EBDAAA889E6CAA3DA96C4C6EA59" xlink:to="loc_endp_AdrenalinMember_390616CC4E5C6FCAAD1DDA96C4C6F729" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_AplisolMember" xlink:label="loc_endp_AplisolMember_342602701A20FFE050B7DB12F75BEBD3" xlink:type="locator" />
    <link:presentationArc order="11" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_2AA86EBDAAA889E6CAA3DA96C4C6EA59" xlink:to="loc_endp_AplisolMember_342602701A20FFE050B7DB12F75BEBD3" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_ErtapenemForInjectionMember" xlink:label="loc_endp_ErtapenemForInjectionMember_A3093B2968ED5E2CF492DA96C4C67511" xlink:type="locator" />
    <link:presentationArc order="12" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_2AA86EBDAAA889E6CAA3DA96C4C6EA59" xlink:to="loc_endp_ErtapenemForInjectionMember_A3093B2968ED5E2CF492DA96C4C67511" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_OtherSterileInjectablesMember" xlink:label="loc_endp_OtherSterileInjectablesMember_AF7A0008DB2BB21DBD37DA96C4CAED2E" xlink:type="locator" />
    <link:presentationArc order="13" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_2AA86EBDAAA889E6CAA3DA96C4C6EA59" xlink:to="loc_endp_OtherSterileInjectablesMember_AF7A0008DB2BB21DBD37DA96C4CAED2E" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_ColchicineTabletsMember" xlink:label="loc_endp_ColchicineTabletsMember_5B042A156F6C867FB31CDA96C4CA3D66" xlink:type="locator" />
    <link:presentationArc order="14" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_2AA86EBDAAA889E6CAA3DA96C4C6EA59" xlink:to="loc_endp_ColchicineTabletsMember_5B042A156F6C867FB31CDA96C4CA3D66" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StatementBusinessSegmentsAxis" xlink:label="loc_us-gaap_StatementBusinessSegmentsAxis_F68E29D266805EDAE590DA96C4CABAA0" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisaggregationOfRevenueTable_F76C987A2A3B8DEE01A9DA96C4C6A706" xlink:to="loc_us-gaap_StatementBusinessSegmentsAxis_F68E29D266805EDAE590DA96C4CABAA0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SegmentDomain" xlink:label="loc_us-gaap_SegmentDomain_F4F40DE2C13EB93B831EDA96C4CAFA5D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_F68E29D266805EDAE590DA96C4CABAA0" xlink:to="loc_us-gaap_SegmentDomain_F4F40DE2C13EB93B831EDA96C4CAFA5D" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_BrandedSpecialtyandEstablishedPharmaceuticalsMember" xlink:label="loc_endp_BrandedSpecialtyandEstablishedPharmaceuticalsMember_5CBB7CEEFEE3E3421058DA96C4CAB608" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_F4F40DE2C13EB93B831EDA96C4CAFA5D" xlink:to="loc_endp_BrandedSpecialtyandEstablishedPharmaceuticalsMember_5CBB7CEEFEE3E3421058DA96C4CAB608" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_BrandedSterileInjectablesMember" xlink:label="loc_endp_BrandedSterileInjectablesMember_87E08C0F07D34C6812D8DA96C4CAEA00" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_F4F40DE2C13EB93B831EDA96C4CAFA5D" xlink:to="loc_endp_BrandedSterileInjectablesMember_87E08C0F07D34C6812D8DA96C4CAEA00" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_GenericPharmaceuticalsMember" xlink:label="loc_endp_GenericPharmaceuticalsMember_BDE9F0D573BFD011F843DA96C4CA34DB" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_F4F40DE2C13EB93B831EDA96C4CAFA5D" xlink:to="loc_endp_GenericPharmaceuticalsMember_BDE9F0D573BFD011F843DA96C4CA34DB" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_InternationalPharmaceuticalsMember" xlink:label="loc_endp_InternationalPharmaceuticalsMember_0721191C411C8EF6F4F4DA96C4CA628B" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_F4F40DE2C13EB93B831EDA96C4CAFA5D" xlink:to="loc_endp_InternationalPharmaceuticalsMember_0721191C411C8EF6F4F4DA96C4CA628B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ConcentrationRiskByBenchmarkAxis" xlink:label="loc_us-gaap_ConcentrationRiskByBenchmarkAxis_9EBF026D24F9C47650BCDA96C4CA1F81" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisaggregationOfRevenueTable_F76C987A2A3B8DEE01A9DA96C4C6A706" xlink:to="loc_us-gaap_ConcentrationRiskByBenchmarkAxis_9EBF026D24F9C47650BCDA96C4CA1F81" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ConcentrationRiskBenchmarkDomain" xlink:label="loc_us-gaap_ConcentrationRiskBenchmarkDomain_38802AC581A381643649DA96C4CA7AD5" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskByBenchmarkAxis_9EBF026D24F9C47650BCDA96C4CA1F81" xlink:to="loc_us-gaap_ConcentrationRiskBenchmarkDomain_38802AC581A381643649DA96C4CA7AD5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SalesRevenueNetMember" xlink:label="loc_us-gaap_SalesRevenueNetMember_99F86DADCF1634EE6BD9DA96C4CA7642" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskBenchmarkDomain_38802AC581A381643649DA96C4CA7AD5" xlink:to="loc_us-gaap_SalesRevenueNetMember_99F86DADCF1634EE6BD9DA96C4CA7642" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ConcentrationRiskByTypeAxis" xlink:label="loc_us-gaap_ConcentrationRiskByTypeAxis_67578AEF7F561769F098DA96C4CA9093" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisaggregationOfRevenueTable_F76C987A2A3B8DEE01A9DA96C4C6A706" xlink:to="loc_us-gaap_ConcentrationRiskByTypeAxis_67578AEF7F561769F098DA96C4CA9093" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ConcentrationRiskTypeDomain" xlink:label="loc_us-gaap_ConcentrationRiskTypeDomain_FB859142169C644F122EDA96C4CA4058" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskByTypeAxis_67578AEF7F561769F098DA96C4CA9093" xlink:to="loc_us-gaap_ConcentrationRiskTypeDomain_FB859142169C644F122EDA96C4CA4058" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ProductConcentrationRiskMember" xlink:label="loc_us-gaap_ProductConcentrationRiskMember_3AB1AE27ABB94FFF8314DA96C4CA13BB" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskTypeDomain_FB859142169C644F122EDA96C4CA4058" xlink:to="loc_us-gaap_ProductConcentrationRiskMember_3AB1AE27ABB94FFF8314DA96C4CA13BB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DisaggregationOfRevenueLineItems" xlink:label="loc_us-gaap_DisaggregationOfRevenueLineItems_C7D6E6366BBC3A6DE60BDA96C4CA71FA" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisaggregationOfRevenueTable_F76C987A2A3B8DEE01A9DA96C4C6A706" xlink:to="loc_us-gaap_DisaggregationOfRevenueLineItems_C7D6E6366BBC3A6DE60BDA96C4CA71FA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_Revenues" xlink:label="loc_us-gaap_Revenues_EE625F91FED0E13E4F42DA96C4CAEB4C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisaggregationOfRevenueLineItems_C7D6E6366BBC3A6DE60BDA96C4CA71FA" xlink:to="loc_us-gaap_Revenues_EE625F91FED0E13E4F42DA96C4CAEB4C" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_ProductLineRevenueReportingThreshold" xlink:label="loc_endp_ProductLineRevenueReportingThreshold_5271A5B067595D05DFDEDA96C4CAD8F9" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisaggregationOfRevenueLineItems_C7D6E6366BBC3A6DE60BDA96C4CA71FA" xlink:to="loc_endp_ProductLineRevenueReportingThreshold_5271A5B067595D05DFDEDA96C4CAD8F9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ConcentrationRiskPercentage1" xlink:label="loc_us-gaap_ConcentrationRiskPercentage1_0AC61EF91E0DAFD00AF3DA96C4CAA830" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisaggregationOfRevenueLineItems_C7D6E6366BBC3A6DE60BDA96C4CA71FA" xlink:to="loc_us-gaap_ConcentrationRiskPercentage1_0AC61EF91E0DAFD00AF3DA96C4CAA830" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/SegmentResultsScheduleOfReconciliationsOfConsolidatedAdjustedIncomeLossBeforeIncomeTaxDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SegmentReportingAbstract" xlink:label="loc_us-gaap_SegmentReportingAbstract_AE3BA98AA5E870E8DC532459352E92BD" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable" xlink:label="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_00403FBE74A9FC1D07CF2459352E1523" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingAbstract_AE3BA98AA5E870E8DC532459352E92BD" xlink:to="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_00403FBE74A9FC1D07CF2459352E1523" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_ConsolidationItemsAxis" xlink:label="loc_srt_ConsolidationItemsAxis_4C49F55AAB49312695132459352E9990" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_00403FBE74A9FC1D07CF2459352E1523" xlink:to="loc_srt_ConsolidationItemsAxis_4C49F55AAB49312695132459352E9990" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_ConsolidationItemsDomain" xlink:label="loc_srt_ConsolidationItemsDomain_C1F30E66757697E68A742459352E0CA5" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ConsolidationItemsAxis_4C49F55AAB49312695132459352E9990" xlink:to="loc_srt_ConsolidationItemsDomain_C1F30E66757697E68A742459352E0CA5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_MaterialReconcilingItemsMember" xlink:label="loc_us-gaap_MaterialReconcilingItemsMember_651F52994273B05C79262459352F444E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ConsolidationItemsDomain_C1F30E66757697E68A742459352E0CA5" xlink:to="loc_us-gaap_MaterialReconcilingItemsMember_651F52994273B05C79262459352F444E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OperatingSegmentsMember" xlink:label="loc_us-gaap_OperatingSegmentsMember_E4C9CB05362569FCF8E42459352F0BF0" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ConsolidationItemsDomain_C1F30E66757697E68A742459352E0CA5" xlink:to="loc_us-gaap_OperatingSegmentsMember_E4C9CB05362569FCF8E42459352F0BF0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestructuringCostAndReserveAxis" xlink:label="loc_us-gaap_RestructuringCostAndReserveAxis_89DF522CC1B825A68B302459352F3938" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_00403FBE74A9FC1D07CF2459352E1523" xlink:to="loc_us-gaap_RestructuringCostAndReserveAxis_89DF522CC1B825A68B302459352F3938" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_TypeOfRestructuringDomain" xlink:label="loc_us-gaap_TypeOfRestructuringDomain_BE8C9EA92F77FA3930332459352F5D9A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringCostAndReserveAxis_89DF522CC1B825A68B302459352F3938" xlink:to="loc_us-gaap_TypeOfRestructuringDomain_BE8C9EA92F77FA3930332459352F5D9A" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_RetentionBonusMember" xlink:label="loc_endp_RetentionBonusMember_62003C33C0956FC795F724593530C3D8" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfRestructuringDomain_BE8C9EA92F77FA3930332459352F5D9A" xlink:to="loc_endp_RetentionBonusMember_62003C33C0956FC795F724593530C3D8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OtherRestructuringMember" xlink:label="loc_us-gaap_OtherRestructuringMember_840E29A8122ADC33141C245935303BDC" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfRestructuringDomain_BE8C9EA92F77FA3930332459352F5D9A" xlink:to="loc_us-gaap_OtherRestructuringMember_840E29A8122ADC33141C245935303BDC" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_InventoryWriteOffsMember" xlink:label="loc_endp_InventoryWriteOffsMember_64297AB0AF867DA0E5D824593530EEBC" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfRestructuringDomain_BE8C9EA92F77FA3930332459352F5D9A" xlink:to="loc_endp_InventoryWriteOffsMember_64297AB0AF867DA0E5D824593530EEBC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ContractTerminationMember" xlink:label="loc_us-gaap_ContractTerminationMember_6869FF3A6A75F94A4562245935300F9F" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfRestructuringDomain_BE8C9EA92F77FA3930332459352F5D9A" xlink:to="loc_us-gaap_ContractTerminationMember_6869FF3A6A75F94A4562245935300F9F" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_InsuranceProgramPremiumMember" xlink:label="loc_endp_InsuranceProgramPremiumMember_72F03B7858EEFC6B395224593530D432" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfRestructuringDomain_BE8C9EA92F77FA3930332459352F5D9A" xlink:to="loc_endp_InsuranceProgramPremiumMember_72F03B7858EEFC6B395224593530D432" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SegmentReportingInformationLineItems" xlink:label="loc_us-gaap_SegmentReportingInformationLineItems_7A26233E0ADA9C37097C245935310D36" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_00403FBE74A9FC1D07CF2459352E1523" xlink:to="loc_us-gaap_SegmentReportingInformationLineItems_7A26233E0ADA9C37097C245935310D36" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ConcentrationRiskPercentage1" xlink:label="loc_us-gaap_ConcentrationRiskPercentage1_28072935C653E0940927245935315E15" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_7A26233E0ADA9C37097C245935310D36" xlink:to="loc_us-gaap_ConcentrationRiskPercentage1_28072935C653E0940927245935315E15" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_FFC6D2C172B796D847E624593531BDE1" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_7A26233E0ADA9C37097C245935310D36" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_FFC6D2C172B796D847E624593531BDE1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_InterestIncomeExpenseNet" xlink:label="loc_us-gaap_InterestIncomeExpenseNet_7B5DB58885AC1E64956F2459353120A6" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_7A26233E0ADA9C37097C245935310D36" xlink:to="loc_us-gaap_InterestIncomeExpenseNet_7B5DB58885AC1E64956F2459353120A6" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_SegmentReportingInformationUnallocatedCorporateExpense" xlink:label="loc_endp_SegmentReportingInformationUnallocatedCorporateExpense_2EACFD1E62778A97249524593531A5BB" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_7A26233E0ADA9C37097C245935310D36" xlink:to="loc_endp_SegmentReportingInformationUnallocatedCorporateExpense_2EACFD1E62778A97249524593531A5BB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AmortizationOfIntangibleAssets" xlink:label="loc_us-gaap_AmortizationOfIntangibleAssets_E35B629A4A1232A1BED52459353282B0" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_7A26233E0ADA9C37097C245935310D36" xlink:to="loc_us-gaap_AmortizationOfIntangibleAssets_E35B629A4A1232A1BED52459353282B0" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_InventoryStepUp" xlink:label="loc_endp_InventoryStepUp_14FDC9CAB5E4019C978424593532B8C4" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_7A26233E0ADA9C37097C245935310D36" xlink:to="loc_endp_InventoryStepUp_14FDC9CAB5E4019C978424593532B8C4" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_UpfrontAndMilestonePaymentsToPartners" xlink:label="loc_endp_UpfrontAndMilestonePaymentsToPartners_90B8F5042F10E61D176024593532C5BA" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_7A26233E0ADA9C37097C245935310D36" xlink:to="loc_endp_UpfrontAndMilestonePaymentsToPartners_90B8F5042F10E61D176024593532C5BA" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_CostReductionInitiatives" xlink:label="loc_endp_CostReductionInitiatives_8A5C610B96E87D5014DF2459353274FB" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_7A26233E0ADA9C37097C245935310D36" xlink:to="loc_endp_CostReductionInitiatives_8A5C610B96E87D5014DF2459353274FB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LossContingencyLossInPeriod" xlink:label="loc_us-gaap_LossContingencyLossInPeriod_79B6521211A48D9B3F9024593532BB8B" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_7A26233E0ADA9C37097C245935310D36" xlink:to="loc_us-gaap_LossContingencyLossInPeriod_79B6521211A48D9B3F9024593532BB8B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AssetImpairmentCharges" xlink:label="loc_us-gaap_AssetImpairmentCharges_B756E12476EC38B70A4A245935321F92" xlink:type="locator" />
    <link:presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_7A26233E0ADA9C37097C245935310D36" xlink:to="loc_us-gaap_AssetImpairmentCharges_B756E12476EC38B70A4A245935321F92" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessCombinationAcquisitionRelatedCosts" xlink:label="loc_us-gaap_BusinessCombinationAcquisitionRelatedCosts_BAE6D4A5345035E3D57024593533A7C3" xlink:type="locator" />
    <link:presentationArc order="11" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_7A26233E0ADA9C37097C245935310D36" xlink:to="loc_us-gaap_BusinessCombinationAcquisitionRelatedCosts_BAE6D4A5345035E3D57024593533A7C3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_GainsLossesOnExtinguishmentOfDebt" xlink:label="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_897BA521983777982BD524593533A1AC" xlink:type="locator" />
    <link:presentationArc order="12" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_7A26233E0ADA9C37097C245935310D36" xlink:to="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_897BA521983777982BD524593533A1AC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AdjustmentForLongTermIntercompanyTransactionsGrossOfTax" xlink:label="loc_us-gaap_AdjustmentForLongTermIntercompanyTransactionsGrossOfTax_1D8392616D525BBB44B92459353379F1" xlink:type="locator" />
    <link:presentationArc order="13" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_7A26233E0ADA9C37097C245935310D36" xlink:to="loc_us-gaap_AdjustmentForLongTermIntercompanyTransactionsGrossOfTax_1D8392616D525BBB44B92459353379F1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OtherNonrecurringIncomeExpense" xlink:label="loc_us-gaap_OtherNonrecurringIncomeExpense_FE3ECD8974599CBC134D24593533C102" xlink:type="locator" />
    <link:presentationArc order="14" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_7A26233E0ADA9C37097C245935310D36" xlink:to="loc_us-gaap_OtherNonrecurringIncomeExpense_FE3ECD8974599CBC134D24593533C102" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_FC96D3034428AFFB6597245935338C8D" xlink:type="locator" />
    <link:presentationArc order="15" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_7A26233E0ADA9C37097C245935310D36" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_FC96D3034428AFFB6597245935338C8D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SeveranceCosts1" xlink:label="loc_us-gaap_SeveranceCosts1_731C1FE2ED213B60971A245935330A06" xlink:type="locator" />
    <link:presentationArc order="16" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_7A26233E0ADA9C37097C245935310D36" xlink:to="loc_us-gaap_SeveranceCosts1_731C1FE2ED213B60971A245935330A06" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestructuringCharges" xlink:label="loc_us-gaap_RestructuringCharges_0F11D73426B590A55112245935348EDF" xlink:type="locator" />
    <link:presentationArc order="17" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_7A26233E0ADA9C37097C245935310D36" xlink:to="loc_us-gaap_RestructuringCharges_0F11D73426B590A55112245935348EDF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestructuringReserveAcceleratedDepreciation" xlink:label="loc_us-gaap_RestructuringReserveAcceleratedDepreciation_787BF1490D9229C01F192459353422E2" xlink:type="locator" />
    <link:presentationArc order="18" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_7A26233E0ADA9C37097C245935310D36" xlink:to="loc_us-gaap_RestructuringReserveAcceleratedDepreciation_787BF1490D9229C01F192459353422E2" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/SegmentResultsScheduleOfReportableSegmentsInformationDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SegmentReportingAbstract" xlink:label="loc_us-gaap_SegmentReportingAbstract_DE793CD19937351CB59645F7E27B9458" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable" xlink:label="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_0DA41BA6F81E741A106A45F7E27B7FD3" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingAbstract_DE793CD19937351CB59645F7E27B9458" xlink:to="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_0DA41BA6F81E741A106A45F7E27B7FD3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StatementBusinessSegmentsAxis" xlink:label="loc_us-gaap_StatementBusinessSegmentsAxis_B3C0868A2F2AA8DF40A545F7E27CE045" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_0DA41BA6F81E741A106A45F7E27B7FD3" xlink:to="loc_us-gaap_StatementBusinessSegmentsAxis_B3C0868A2F2AA8DF40A545F7E27CE045" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SegmentDomain" xlink:label="loc_us-gaap_SegmentDomain_484A3A1253AE4D84D44845F7E27CC4A7" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_B3C0868A2F2AA8DF40A545F7E27CE045" xlink:to="loc_us-gaap_SegmentDomain_484A3A1253AE4D84D44845F7E27CC4A7" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_BrandedSpecialtyandEstablishedPharmaceuticalsMember" xlink:label="loc_endp_BrandedSpecialtyandEstablishedPharmaceuticalsMember_1C6B4AD71238A683D7C845F7E27D419F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_484A3A1253AE4D84D44845F7E27CC4A7" xlink:to="loc_endp_BrandedSpecialtyandEstablishedPharmaceuticalsMember_1C6B4AD71238A683D7C845F7E27D419F" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_BrandedSterileInjectablesMember" xlink:label="loc_endp_BrandedSterileInjectablesMember_453F51882DA90AC7903A45F7E27DCACF" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_484A3A1253AE4D84D44845F7E27CC4A7" xlink:to="loc_endp_BrandedSterileInjectablesMember_453F51882DA90AC7903A45F7E27DCACF" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_GenericPharmaceuticalsMember" xlink:label="loc_endp_GenericPharmaceuticalsMember_D163CE02A798E6099FC145F7E27D177A" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_484A3A1253AE4D84D44845F7E27CC4A7" xlink:to="loc_endp_GenericPharmaceuticalsMember_D163CE02A798E6099FC145F7E27D177A" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_InternationalPharmaceuticalsMember" xlink:label="loc_endp_InternationalPharmaceuticalsMember_00468BBD4A8A15CF5D2645F7E27DB8D7" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_484A3A1253AE4D84D44845F7E27CC4A7" xlink:to="loc_endp_InternationalPharmaceuticalsMember_00468BBD4A8A15CF5D2645F7E27DB8D7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SegmentReportingInformationLineItems" xlink:label="loc_us-gaap_SegmentReportingInformationLineItems_AEAEDF3B9D01F1BB828145F7E27D6BFB" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_0DA41BA6F81E741A106A45F7E27B7FD3" xlink:to="loc_us-gaap_SegmentReportingInformationLineItems_AEAEDF3B9D01F1BB828145F7E27D6BFB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_NumberOfReportableSegments" xlink:label="loc_us-gaap_NumberOfReportableSegments_106EF10122F96DDF63B545F7E27ED0C3" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_AEAEDF3B9D01F1BB828145F7E27D6BFB" xlink:to="loc_us-gaap_NumberOfReportableSegments_106EF10122F96DDF63B545F7E27ED0C3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_Revenues" xlink:label="loc_us-gaap_Revenues_063ED4BF91BB7C68DA1845F7E27EDF23" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/netLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_AEAEDF3B9D01F1BB828145F7E27D6BFB" xlink:to="loc_us-gaap_Revenues_063ED4BF91BB7C68DA1845F7E27EDF23" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_AdjustedIncomeLossBeforeIncomeTax" xlink:label="loc_endp_AdjustedIncomeLossBeforeIncomeTax_1A76D1DED6AE5AD8AFAA45F7E27E6908" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_AEAEDF3B9D01F1BB828145F7E27D6BFB" xlink:to="loc_endp_AdjustedIncomeLossBeforeIncomeTax_1A76D1DED6AE5AD8AFAA45F7E27E6908" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/SegmentResultsTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SegmentReportingAbstract" xlink:label="loc_us-gaap_SegmentReportingAbstract_5855863079805C8E9D3FCA2CB82CA602" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfSegmentReportingInformationBySegmentTextBlock" xlink:label="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTextBlock_EA3E0DEAC55E59329CEE2B5F5B8FE984" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingAbstract_5855863079805C8E9D3FCA2CB82CA602" xlink:to="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTextBlock_EA3E0DEAC55E59329CEE2B5F5B8FE984" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DisaggregationOfRevenueTableTextBlock" xlink:label="loc_us-gaap_DisaggregationOfRevenueTableTextBlock_2F540D288C1F57169183F006C01D03E4" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingAbstract_5855863079805C8E9D3FCA2CB82CA602" xlink:to="loc_us-gaap_DisaggregationOfRevenueTableTextBlock_2F540D288C1F57169183F006C01D03E4" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/ShareholdersDeficit" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EquityAbstract" xlink:label="loc_us-gaap_EquityAbstract_2E73A463068C55D89E8DA63B39BC828A" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StockholdersEquityNoteDisclosureTextBlock" xlink:label="loc_us-gaap_StockholdersEquityNoteDisclosureTextBlock_6F7E2E7DEF945120AC7263A6C97EF377" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_2E73A463068C55D89E8DA63B39BC828A" xlink:to="loc_us-gaap_StockholdersEquityNoteDisclosureTextBlock_6F7E2E7DEF945120AC7263A6C97EF377" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/ShareholdersDeficitEquityNarrativeDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EquityAbstract" xlink:label="loc_us-gaap_EquityAbstract_49BF96048298050E8BAADB1E03DFE167" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_51311CE8B5F8A009A367DB1E03F3301F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_49BF96048298050E8BAADB1E03DFE167" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_51311CE8B5F8A009A367DB1E03F3301F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AwardTypeAxis" xlink:label="loc_us-gaap_AwardTypeAxis_E3B3962F0F20E5EDF908DB1E03F55257" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_51311CE8B5F8A009A367DB1E03F3301F" xlink:to="loc_us-gaap_AwardTypeAxis_E3B3962F0F20E5EDF908DB1E03F55257" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_10496C9D8ED70472616CDB1E03F5AA01" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_E3B3962F0F20E5EDF908DB1E03F55257" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_10496C9D8ED70472616CDB1E03F5AA01" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_NonVestedStockOptionsMember" xlink:label="loc_endp_NonVestedStockOptionsMember_EA61168868579A0D2F30DB1E03F52384" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_10496C9D8ED70472616CDB1E03F5AA01" xlink:to="loc_endp_NonVestedStockOptionsMember_EA61168868579A0D2F30DB1E03F52384" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_NonVestedRestrictedStockMember" xlink:label="loc_endp_NonVestedRestrictedStockMember_DF0F0F644C6AEBAFDBB0DB1E03F63C29" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_10496C9D8ED70472616CDB1E03F5AA01" xlink:to="loc_endp_NonVestedRestrictedStockMember_DF0F0F644C6AEBAFDBB0DB1E03F63C29" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StatementEquityComponentsAxis" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_41977C758FB98740961EDB1E03F6AC5B" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_51311CE8B5F8A009A367DB1E03F3301F" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_41977C758FB98740961EDB1E03F6AC5B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EquityComponentDomain" xlink:label="loc_us-gaap_EquityComponentDomain_ACB6C9155A6F4829DC41DB1E03F62F27" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_41977C758FB98740961EDB1E03F6AC5B" xlink:to="loc_us-gaap_EquityComponentDomain_ACB6C9155A6F4829DC41DB1E03F62F27" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AdditionalPaidInCapitalMember" xlink:label="loc_us-gaap_AdditionalPaidInCapitalMember_6884D2CE195D4020C730DB1E03F6FFF2" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_ACB6C9155A6F4829DC41DB1E03F62F27" xlink:to="loc_us-gaap_AdditionalPaidInCapitalMember_6884D2CE195D4020C730DB1E03F6FFF2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_7EBE6286E837470B0DA9DB1E03F7BF82" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_51311CE8B5F8A009A367DB1E03F3301F" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_7EBE6286E837470B0DA9DB1E03F7BF82" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue" xlink:label="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue_AAD70B5E05D62B6E6166DB1E03F77434" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_7EBE6286E837470B0DA9DB1E03F7BF82" xlink:to="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue_AAD70B5E05D62B6E6166DB1E03F77434" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognized" xlink:label="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognized_63CF5C1A38DD93B97CD7DB1E03F70750" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_7EBE6286E837470B0DA9DB1E03F7BF82" xlink:to="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognized_63CF5C1A38DD93B97CD7DB1E03F70750" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardRequisiteServicePeriod1" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardRequisiteServicePeriod1_9F73B707AE5E4024A0B8DB1E03F7338E" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_7EBE6286E837470B0DA9DB1E03F7BF82" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardRequisiteServicePeriod1_9F73B707AE5E4024A0B8DB1E03F7338E" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/ShareholdersDeficitScheduleOfChangesInShareholdersEquityDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EquityAbstract" xlink:label="loc_us-gaap_EquityAbstract_6CB829B99D5092D0ADBB50DDDA487680" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossTable" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossTable_5273008D9E61075113BA50DDDA49232E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_6CB829B99D5092D0ADBB50DDDA487680" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossTable_5273008D9E61075113BA50DDDA49232E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_InitialApplicationPeriodCumulativeEffectTransitionAxis" xlink:label="loc_us-gaap_InitialApplicationPeriodCumulativeEffectTransitionAxis_F97DB1AFF46EFBD2CACB50DDDA49026E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossTable_5273008D9E61075113BA50DDDA49232E" xlink:to="loc_us-gaap_InitialApplicationPeriodCumulativeEffectTransitionAxis_F97DB1AFF46EFBD2CACB50DDDA49026E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_InitialApplicationPeriodCumulativeEffectTransitionDomain" xlink:label="loc_us-gaap_InitialApplicationPeriodCumulativeEffectTransitionDomain_0339545E2114A15A294650DDDA4A9256" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InitialApplicationPeriodCumulativeEffectTransitionAxis_F97DB1AFF46EFBD2CACB50DDDA49026E" xlink:to="loc_us-gaap_InitialApplicationPeriodCumulativeEffectTransitionDomain_0339545E2114A15A294650DDDA4A9256" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DifferenceBetweenRevenueGuidanceInEffectBeforeAndAfterTopic606Member" xlink:label="loc_us-gaap_DifferenceBetweenRevenueGuidanceInEffectBeforeAndAfterTopic606Member_4E1BF2D0D4291671616350DDDA4AA16F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InitialApplicationPeriodCumulativeEffectTransitionDomain_0339545E2114A15A294650DDDA4A9256" xlink:to="loc_us-gaap_DifferenceBetweenRevenueGuidanceInEffectBeforeAndAfterTopic606Member_4E1BF2D0D4291671616350DDDA4AA16F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AdjustmentsForNewAccountingPronouncementsAxis" xlink:label="loc_us-gaap_AdjustmentsForNewAccountingPronouncementsAxis_68C2F6BAD68A85958A5E50DDDA4A0BA2" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossTable_5273008D9E61075113BA50DDDA49232E" xlink:to="loc_us-gaap_AdjustmentsForNewAccountingPronouncementsAxis_68C2F6BAD68A85958A5E50DDDA4A0BA2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_TypeOfAdoptionMember" xlink:label="loc_us-gaap_TypeOfAdoptionMember_0346F02B20A227E378FB50DDDA4A20C8" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsForNewAccountingPronouncementsAxis_68C2F6BAD68A85958A5E50DDDA4A0BA2" xlink:to="loc_us-gaap_TypeOfAdoptionMember_0346F02B20A227E378FB50DDDA4A20C8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AccountingStandardsUpdate201409Member" xlink:label="loc_us-gaap_AccountingStandardsUpdate201409Member_5CFBF13482755C67D0CE50DDDA4B7A19" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfAdoptionMember_0346F02B20A227E378FB50DDDA4A20C8" xlink:to="loc_us-gaap_AccountingStandardsUpdate201409Member_5CFBF13482755C67D0CE50DDDA4B7A19" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StatementEquityComponentsAxis" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_03F2EBE9373B90E2008950DDDA4B07BB" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossTable_5273008D9E61075113BA50DDDA49232E" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_03F2EBE9373B90E2008950DDDA4B07BB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EquityComponentDomain" xlink:label="loc_us-gaap_EquityComponentDomain_48291548BB08BD41A94250DDDA4B5AFF" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_03F2EBE9373B90E2008950DDDA4B07BB" xlink:to="loc_us-gaap_EquityComponentDomain_48291548BB08BD41A94250DDDA4B5AFF" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_EuroDeferredSharesMember" xlink:label="loc_endp_EuroDeferredSharesMember_70BD80A0267E9FDEBB8C50DDDA4C07C9" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_48291548BB08BD41A94250DDDA4B5AFF" xlink:to="loc_endp_EuroDeferredSharesMember_70BD80A0267E9FDEBB8C50DDDA4C07C9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CommonStockMember" xlink:label="loc_us-gaap_CommonStockMember_713DB870032EE4C7F3F150DDDA4C495C" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_48291548BB08BD41A94250DDDA4B5AFF" xlink:to="loc_us-gaap_CommonStockMember_713DB870032EE4C7F3F150DDDA4C495C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AdditionalPaidInCapitalMember" xlink:label="loc_us-gaap_AdditionalPaidInCapitalMember_4DD4138338A17BBEAC3450DDDA4C9CA9" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_48291548BB08BD41A94250DDDA4B5AFF" xlink:to="loc_us-gaap_AdditionalPaidInCapitalMember_4DD4138338A17BBEAC3450DDDA4C9CA9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RetainedEarningsMember" xlink:label="loc_us-gaap_RetainedEarningsMember_4431947EAF2EA38A367550DDDA4CA257" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_48291548BB08BD41A94250DDDA4B5AFF" xlink:to="loc_us-gaap_RetainedEarningsMember_4431947EAF2EA38A367550DDDA4CA257" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeMember" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeMember_7D48F1B1051FE7ECF46950DDDA4DDEB5" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_48291548BB08BD41A94250DDDA4B5AFF" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeMember_7D48F1B1051FE7ECF46950DDDA4DDEB5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_5097C297F8164634C6B250DDDA4D385D" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossTable_5273008D9E61075113BA50DDDA49232E" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_5097C297F8164634C6B250DDDA4D385D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncreaseDecreaseInStockholdersEquityRollForward" xlink:label="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_11609BE07BF21A47DBE450DDDA4D499B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_5097C297F8164634C6B250DDDA4D385D" xlink:to="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_11609BE07BF21A47DBE450DDDA4D499B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StockholdersEquity" xlink:label="loc_us-gaap_StockholdersEquity_39997186EF4F23707A5550DDDA4E62C6" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_11609BE07BF21A47DBE450DDDA4D499B" xlink:to="loc_us-gaap_StockholdersEquity_39997186EF4F23707A5550DDDA4E62C6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CumulativeEffectOfNewAccountingPrincipleInPeriodOfAdoption" xlink:label="loc_us-gaap_CumulativeEffectOfNewAccountingPrincipleInPeriodOfAdoption_1A460B8BB8097FBB759950DDDA4ECDEE" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_11609BE07BF21A47DBE450DDDA4D499B" xlink:to="loc_us-gaap_CumulativeEffectOfNewAccountingPrincipleInPeriodOfAdoption_1A460B8BB8097FBB759950DDDA4ECDEE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterestAdjustedBalance1" xlink:label="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterestAdjustedBalance1_2BDCC95ABD4A5134EB5D50DDDA4ED76D" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_11609BE07BF21A47DBE450DDDA4D499B" xlink:to="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterestAdjustedBalance1_2BDCC95ABD4A5134EB5D50DDDA4ED76D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_NetIncomeLoss" xlink:label="loc_us-gaap_NetIncomeLoss_BE31CD3C85170B7C0FCB50DDDA4EA5CA" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_11609BE07BF21A47DBE450DDDA4D499B" xlink:to="loc_us-gaap_NetIncomeLoss_BE31CD3C85170B7C0FCB50DDDA4EA5CA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_7D6124BB0DD369DBABE950DDDA4EDC21" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_11609BE07BF21A47DBE450DDDA4D499B" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_7D6124BB0DD369DBABE950DDDA4EDC21" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue" xlink:label="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue_BA72A94ABB0EB30145CB50DDDA4F7F1F" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_11609BE07BF21A47DBE450DDDA4D499B" xlink:to="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue_BA72A94ABB0EB30145CB50DDDA4F7F1F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised" xlink:label="loc_us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised_F33E077AFD4E8CB64D0850DDDA4F108B" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_11609BE07BF21A47DBE450DDDA4D499B" xlink:to="loc_us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised_F33E077AFD4E8CB64D0850DDDA4F108B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AdjustmentsRelatedToTaxWithholdingForShareBasedCompensation" xlink:label="loc_us-gaap_AdjustmentsRelatedToTaxWithholdingForShareBasedCompensation_304C051D094C36F6E59D50DDDA4FE1A5" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_11609BE07BF21A47DBE450DDDA4D499B" xlink:to="loc_us-gaap_AdjustmentsRelatedToTaxWithholdingForShareBasedCompensation_304C051D094C36F6E59D50DDDA4FE1A5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StockholdersEquityOther" xlink:label="loc_us-gaap_StockholdersEquityOther_A3BC032A819F000ED6F550DDDA4F006C" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_11609BE07BF21A47DBE450DDDA4D499B" xlink:to="loc_us-gaap_StockholdersEquityOther_A3BC032A819F000ED6F550DDDA4F006C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StockholdersEquity" xlink:label="loc_us-gaap_StockholdersEquity_E3014534937270FA123550DDDA4F061A" xlink:type="locator" />
    <link:presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_11609BE07BF21A47DBE450DDDA4D499B" xlink:to="loc_us-gaap_StockholdersEquity_E3014534937270FA123550DDDA4F061A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RetainedEarningsAccumulatedDeficit" xlink:label="loc_us-gaap_RetainedEarningsAccumulatedDeficit_5EF917610EAE9626DAA950DDDA50A02C" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_5097C297F8164634C6B250DDDA4D385D" xlink:to="loc_us-gaap_RetainedEarningsAccumulatedDeficit_5EF917610EAE9626DAA950DDDA50A02C" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/ShareholdersDeficitTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EquityAbstract" xlink:label="loc_us-gaap_EquityAbstract_77C83FD748015F9EB0E7AF98B03533AC" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfStockholdersEquityTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfStockholdersEquityTableTextBlock_E693C2535A335C168ACCCCE25034E1E9" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_77C83FD748015F9EB0E7AF98B03533AC" xlink:to="loc_us-gaap_ScheduleOfStockholdersEquityTableTextBlock_E693C2535A335C168ACCCCE25034E1E9" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/SummaryOfSignificantAccountingPolicies" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AccountingPoliciesAbstract" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_71AC2F8EB85B5D2485048E632EB96589" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SignificantAccountingPoliciesTextBlock" xlink:label="loc_us-gaap_SignificantAccountingPoliciesTextBlock_61001265AB6858679A5732CD5410D92D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_71AC2F8EB85B5D2485048E632EB96589" xlink:to="loc_us-gaap_SignificantAccountingPoliciesTextBlock_61001265AB6858679A5732CD5410D92D" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/SummaryOfSignificantAccountingPoliciesNarrativeDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AccountingPoliciesAbstract" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_8DF46DBC0312550CBA9F675935FAC367" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfProductInformationTable" xlink:label="loc_us-gaap_ScheduleOfProductInformationTable_A55EEBF6B13F5710AD50646AC4740048" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_8DF46DBC0312550CBA9F675935FAC367" xlink:to="loc_us-gaap_ScheduleOfProductInformationTable_A55EEBF6B13F5710AD50646AC4740048" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AdjustmentsForNewAccountingPronouncementsAxis" xlink:label="loc_us-gaap_AdjustmentsForNewAccountingPronouncementsAxis_3FEFCC34253654F2B10CC213FF4E5044" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfProductInformationTable_A55EEBF6B13F5710AD50646AC4740048" xlink:to="loc_us-gaap_AdjustmentsForNewAccountingPronouncementsAxis_3FEFCC34253654F2B10CC213FF4E5044" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_TypeOfAdoptionMember" xlink:label="loc_us-gaap_TypeOfAdoptionMember_53B475CCE8CC5503B00D90085F7066D4" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsForNewAccountingPronouncementsAxis_3FEFCC34253654F2B10CC213FF4E5044" xlink:to="loc_us-gaap_TypeOfAdoptionMember_53B475CCE8CC5503B00D90085F7066D4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AccountingStandardsUpdate201602Member" xlink:label="loc_us-gaap_AccountingStandardsUpdate201602Member_B619334C01BF533AB08024AFFC7E9C18" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfAdoptionMember_53B475CCE8CC5503B00D90085F7066D4" xlink:to="loc_us-gaap_AccountingStandardsUpdate201602Member_B619334C01BF533AB08024AFFC7E9C18" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StatementEquityComponentsAxis" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_2997F63200A95BD4AE0714854D665579" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfProductInformationTable_A55EEBF6B13F5710AD50646AC4740048" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_2997F63200A95BD4AE0714854D665579" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EquityComponentDomain" xlink:label="loc_us-gaap_EquityComponentDomain_D941DF9FDA505EB7AD4B7B9D341031AC" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_2997F63200A95BD4AE0714854D665579" xlink:to="loc_us-gaap_EquityComponentDomain_D941DF9FDA505EB7AD4B7B9D341031AC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RetainedEarningsMember" xlink:label="loc_us-gaap_RetainedEarningsMember_95F3BF1AE0E2588DABBA1B2B3904BDB8" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_D941DF9FDA505EB7AD4B7B9D341031AC" xlink:to="loc_us-gaap_RetainedEarningsMember_95F3BF1AE0E2588DABBA1B2B3904BDB8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ProductInformationLineItems" xlink:label="loc_us-gaap_ProductInformationLineItems_382B6FE7E46F53F89A87DC8EDB7D7BA0" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfProductInformationTable_A55EEBF6B13F5710AD50646AC4740048" xlink:to="loc_us-gaap_ProductInformationLineItems_382B6FE7E46F53F89A87DC8EDB7D7BA0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OperatingLeaseRightOfUseAsset" xlink:label="loc_us-gaap_OperatingLeaseRightOfUseAsset_5862AFA900C55476B8355FCE51E5C4F5" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ProductInformationLineItems_382B6FE7E46F53F89A87DC8EDB7D7BA0" xlink:to="loc_us-gaap_OperatingLeaseRightOfUseAsset_5862AFA900C55476B8355FCE51E5C4F5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OperatingLeaseLiabilityCurrent" xlink:label="loc_us-gaap_OperatingLeaseLiabilityCurrent_4E7149CCDB0751468ACE70D29E61D41F" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ProductInformationLineItems_382B6FE7E46F53F89A87DC8EDB7D7BA0" xlink:to="loc_us-gaap_OperatingLeaseLiabilityCurrent_4E7149CCDB0751468ACE70D29E61D41F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OperatingLeaseLiabilityNoncurrent" xlink:label="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_9F5AB1B4E26E53BAB30FA736FE08EE17" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ProductInformationLineItems_382B6FE7E46F53F89A87DC8EDB7D7BA0" xlink:to="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_9F5AB1B4E26E53BAB30FA736FE08EE17" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CumulativeEffectOfNewAccountingPrincipleInPeriodOfAdoption" xlink:label="loc_us-gaap_CumulativeEffectOfNewAccountingPrincipleInPeriodOfAdoption_C924F696FC775D5FB2BFA4322A7CF156" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ProductInformationLineItems_382B6FE7E46F53F89A87DC8EDB7D7BA0" xlink:to="loc_us-gaap_CumulativeEffectOfNewAccountingPrincipleInPeriodOfAdoption_C924F696FC775D5FB2BFA4322A7CF156" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/SummaryOfSignificantAccountingPoliciesPolicies" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AccountingPoliciesAbstract" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_E3FB7563AB455824B3E23483D092A4B3" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LesseeLeasesPolicyTextBlock" xlink:label="loc_us-gaap_LesseeLeasesPolicyTextBlock_B3FFD7CFBBCA51479FC1CD687DD880CF" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_E3FB7563AB455824B3E23483D092A4B3" xlink:to="loc_us-gaap_LesseeLeasesPolicyTextBlock_B3FFD7CFBBCA51479FC1CD687DD880CF" xlink:type="arc" />
    <link:loc xlink:href="endp-20190930.xsd#endp_HostingArrangementServiceContractPolicyTextBlock" xlink:label="loc_endp_HostingArrangementServiceContractPolicyTextBlock_4A60AC91679F55938792AD8115668EDE" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_E3FB7563AB455824B3E23483D092A4B3" xlink:to="loc_endp_HostingArrangementServiceContractPolicyTextBlock_4A60AC91679F55938792AD8115668EDE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock" xlink:label="loc_us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock_FA3C89ACC9E2561A98D8B136C44FAE38" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_E3FB7563AB455824B3E23483D092A4B3" xlink:to="loc_us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock_FA3C89ACC9E2561A98D8B136C44FAE38" xlink:type="arc" />
  </link:presentationLink>
</link:linkbase>




