

<!--XBRL Document Created with Wdesk from Workiva-->
<!-- -->
<link:linkbase xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd" xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
  <link:roleRef roleURI="http://www.endo.com/role/AccountsPayableAndAccruedExpenses" xlink:href="endp-20180331.xsd#AccountsPayableAndAccruedExpenses" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/AccountsPayableAndAccruedExpensesDetails" xlink:href="endp-20180331.xsd#AccountsPayableAndAccruedExpensesDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/AccountsPayableAndAccruedExpensesTables" xlink:href="endp-20180331.xsd#AccountsPayableAndAccruedExpensesTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/BasisOfPresentation" xlink:href="endp-20180331.xsd#BasisOfPresentation" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/BasisOfPresentationBasisDetails" xlink:href="endp-20180331.xsd#BasisOfPresentationBasisDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/BasisOfPresentationScheduleOfEffectOfAdoptionOfAsu201618Details" xlink:href="endp-20180331.xsd#BasisOfPresentationScheduleOfEffectOfAdoptionOfAsu201618Details" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/BasisOfPresentationTables" xlink:href="endp-20180331.xsd#BasisOfPresentationTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/CommitmentsAndContingencies" xlink:href="endp-20180331.xsd#CommitmentsAndContingencies" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/CommitmentsAndContingenciesNarrativeDetails" xlink:href="endp-20180331.xsd#CommitmentsAndContingenciesNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/CommitmentsAndContingenciesScheduleOfLossContingenciesDetails" xlink:href="endp-20180331.xsd#CommitmentsAndContingenciesScheduleOfLossContingenciesDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/CommitmentsAndContingenciesTables" xlink:href="endp-20180331.xsd#CommitmentsAndContingenciesTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/CondensedConsolidatedBalanceSheetsUnaudited" xlink:href="endp-20180331.xsd#CondensedConsolidatedBalanceSheetsUnaudited" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/CondensedConsolidatedBalanceSheetsUnauditedParenthetical" xlink:href="endp-20180331.xsd#CondensedConsolidatedBalanceSheetsUnauditedParenthetical" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/CondensedConsolidatedStatementsOfCashFlowsUnaudited" xlink:href="endp-20180331.xsd#CondensedConsolidatedStatementsOfCashFlowsUnaudited" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/CondensedConsolidatedStatementsOfComprehensiveLossUnaudited" xlink:href="endp-20180331.xsd#CondensedConsolidatedStatementsOfComprehensiveLossUnaudited" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/CondensedConsolidatedStatementsOfOperationsUnaudited" xlink:href="endp-20180331.xsd#CondensedConsolidatedStatementsOfOperationsUnaudited" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/ContractAssetsAndLiabilities" xlink:href="endp-20180331.xsd#ContractAssetsAndLiabilities" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/ContractAssetsAndLiabilitiesDetails" xlink:href="endp-20180331.xsd#ContractAssetsAndLiabilitiesDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/ContractAssetsAndLiabilitiesTables" xlink:href="endp-20180331.xsd#ContractAssetsAndLiabilitiesTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/Debt" xlink:href="endp-20180331.xsd#Debt" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/DebtComponentsOfTotalIndebtednessDetails" xlink:href="endp-20180331.xsd#DebtComponentsOfTotalIndebtednessDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/DebtCreditFacilityNarrativeDetails" xlink:href="endp-20180331.xsd#DebtCreditFacilityNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/DebtTables" xlink:href="endp-20180331.xsd#DebtTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/DiscontinuedOperationsAndDivestitures" xlink:href="endp-20180331.xsd#DiscontinuedOperationsAndDivestitures" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/DiscontinuedOperationsAndDivestituresAstoraDetails" xlink:href="endp-20180331.xsd#DiscontinuedOperationsAndDivestituresAstoraDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/DiscontinuedOperationsAndDivestituresLithiaNarrativeDetails" xlink:href="endp-20180331.xsd#DiscontinuedOperationsAndDivestituresLithiaNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/DiscontinuedOperationsAndDivestituresSomarNarrativeDetails" xlink:href="endp-20180331.xsd#DiscontinuedOperationsAndDivestituresSomarNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/DiscontinuedOperationsAndDivestituresTables" xlink:href="endp-20180331.xsd#DiscontinuedOperationsAndDivestituresTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/DocumentAndEntityInformation" xlink:href="endp-20180331.xsd#DocumentAndEntityInformation" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/FairValueMeasurements" xlink:href="endp-20180331.xsd#FairValueMeasurements" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/FairValueMeasurementsFairValueMeasurementsScheduleOfFinancialAssetsMeasuredAtFairValueOnNonrecurringBasisDetails" xlink:href="endp-20180331.xsd#FairValueMeasurementsFairValueMeasurementsScheduleOfFinancialAssetsMeasuredAtFairValueOnNonrecurringBasisDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/FairValueMeasurementsFinancialAssetsAndLiabilitiesMeasuredAtFairValueOnRecurringBasisDetails" xlink:href="endp-20180331.xsd#FairValueMeasurementsFinancialAssetsAndLiabilitiesMeasuredAtFairValueOnRecurringBasisDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/FairValueMeasurementsFinancialLiabilitiesMeasuredAtFairValueOnRecurringBasisUsingSignificantUnobservableInputsDetails" xlink:href="endp-20180331.xsd#FairValueMeasurementsFinancialLiabilitiesMeasuredAtFairValueOnRecurringBasisUsingSignificantUnobservableInputsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/FairValueMeasurementsNarrativeDetails" xlink:href="endp-20180331.xsd#FairValueMeasurementsNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/FairValueMeasurementsTables" xlink:href="endp-20180331.xsd#FairValueMeasurementsTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/GoodwillAndOtherIntangibles" xlink:href="endp-20180331.xsd#GoodwillAndOtherIntangibles" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/GoodwillAndOtherIntangiblesAccumulatedImpairmentDetails" xlink:href="endp-20180331.xsd#GoodwillAndOtherIntangiblesAccumulatedImpairmentDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/GoodwillAndOtherIntangiblesImpairmentsNarrativeDetails" xlink:href="endp-20180331.xsd#GoodwillAndOtherIntangiblesImpairmentsNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/GoodwillAndOtherIntangiblesOtherIntangiblesNarrativeDetails" xlink:href="endp-20180331.xsd#GoodwillAndOtherIntangiblesOtherIntangiblesNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/GoodwillAndOtherIntangiblesScheduleOfChangesInCarryingAmountOfGoodwillDetails" xlink:href="endp-20180331.xsd#GoodwillAndOtherIntangiblesScheduleOfChangesInCarryingAmountOfGoodwillDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/GoodwillAndOtherIntangiblesScheduleOfEstimatedAmortizationOfIntangiblesDetails" xlink:href="endp-20180331.xsd#GoodwillAndOtherIntangiblesScheduleOfEstimatedAmortizationOfIntangiblesDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/GoodwillAndOtherIntangiblesScheduleOfOtherIntangibleAssetsDetails" xlink:href="endp-20180331.xsd#GoodwillAndOtherIntangiblesScheduleOfOtherIntangibleAssetsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/GoodwillAndOtherIntangiblesTables" xlink:href="endp-20180331.xsd#GoodwillAndOtherIntangiblesTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/IncomeTaxes" xlink:href="endp-20180331.xsd#IncomeTaxes" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/IncomeTaxesNarrativeDetails" xlink:href="endp-20180331.xsd#IncomeTaxesNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/Inventories" xlink:href="endp-20180331.xsd#Inventories" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/InventoriesDetails" xlink:href="endp-20180331.xsd#InventoriesDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/InventoriesTables" xlink:href="endp-20180331.xsd#InventoriesTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/NetLossPerShare" xlink:href="endp-20180331.xsd#NetLossPerShare" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/NetLossPerShareReconciliationOfNumeratorAndDenominatorOfBasicAndDilutedNetLossPerShareDetails" xlink:href="endp-20180331.xsd#NetLossPerShareReconciliationOfNumeratorAndDenominatorOfBasicAndDilutedNetLossPerShareDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/NetLossPerShareTables" xlink:href="endp-20180331.xsd#NetLossPerShareTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/OtherComprehensiveIncomeLossScheduleOfTaxEffectsAllocatedToEachComponentOfOtherComprehensiveIncomeDetails" xlink:href="endp-20180331.xsd#OtherComprehensiveIncomeLossScheduleOfTaxEffectsAllocatedToEachComponentOfOtherComprehensiveIncomeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/OtherComprehensiveIncomeLossTables" xlink:href="endp-20180331.xsd#OtherComprehensiveIncomeLossTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/OtherComprehensiveLossIncome" xlink:href="endp-20180331.xsd#OtherComprehensiveLossIncome" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/OtherIncomeExpenseNetDetails" xlink:href="endp-20180331.xsd#OtherIncomeExpenseNetDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/OtherIncomeExpenseNetTables" xlink:href="endp-20180331.xsd#OtherIncomeExpenseNetTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/OtherIncomeNet" xlink:href="endp-20180331.xsd#OtherIncomeNet" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/Restructuring" xlink:href="endp-20180331.xsd#Restructuring" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/Restructuring2017RestructuringInitiativesNarrativeDetails" xlink:href="endp-20180331.xsd#Restructuring2017RestructuringInitiativesNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/RestructuringJanuary2018RestructuringInitiativeNarrativeDetails" xlink:href="endp-20180331.xsd#RestructuringJanuary2018RestructuringInitiativeNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/RestructuringScheduleOfRestructuringRollForwardDetails" xlink:href="endp-20180331.xsd#RestructuringScheduleOfRestructuringRollForwardDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/RestructuringTables" xlink:href="endp-20180331.xsd#RestructuringTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/SegmentResults" xlink:href="endp-20180331.xsd#SegmentResults" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/SegmentResultsScheduleOfDisaggregationOfRevenuesDetails" xlink:href="endp-20180331.xsd#SegmentResultsScheduleOfDisaggregationOfRevenuesDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/SegmentResultsScheduleOfReconciliationsOfConsolidatedAdjustedIncomeLossBeforeIncomeTaxDetails" xlink:href="endp-20180331.xsd#SegmentResultsScheduleOfReconciliationsOfConsolidatedAdjustedIncomeLossBeforeIncomeTaxDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/SegmentResultsScheduleOfReportableSegmentsInformationDetails" xlink:href="endp-20180331.xsd#SegmentResultsScheduleOfReportableSegmentsInformationDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/SegmentResultsTables" xlink:href="endp-20180331.xsd#SegmentResultsTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/ShareholdersDeficitEquityDetails" xlink:href="endp-20180331.xsd#ShareholdersDeficitEquityDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/ShareholdersDeficitEquityScheduleOfChangesInShareholdersEquityDetails" xlink:href="endp-20180331.xsd#ShareholdersDeficitEquityScheduleOfChangesInShareholdersEquityDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/ShareholdersDeficitEquityShareholdersDeficitEquity" xlink:href="endp-20180331.xsd#ShareholdersDeficitEquityShareholdersDeficitEquity" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/ShareholdersDeficitEquityTables" xlink:href="endp-20180331.xsd#ShareholdersDeficitEquityTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/SubsequentEvents" xlink:href="endp-20180331.xsd#SubsequentEvents" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/SubsequentEventsDetails" xlink:href="endp-20180331.xsd#SubsequentEventsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/SummaryOfSignificantAccountingPolicies" xlink:href="endp-20180331.xsd#SummaryOfSignificantAccountingPolicies" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/SummaryOfSignificantAccountingPoliciesPolicies" xlink:href="endp-20180331.xsd#SummaryOfSignificantAccountingPoliciesPolicies" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/SummaryOfSignificantAccountingPoliciesScheduleOfImpactOfAsc606Details" xlink:href="endp-20180331.xsd#SummaryOfSignificantAccountingPoliciesScheduleOfImpactOfAsc606Details" xlink:type="simple" />
  <link:roleRef roleURI="http://www.endo.com/role/SummaryOfSignificantAccountingPoliciesTables" xlink:href="endp-20180331.xsd#SummaryOfSignificantAccountingPoliciesTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedLabel" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedLabel" xlink:type="simple" />
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedNetLabel" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedNetLabel" xlink:type="simple" />
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedPeriodEndLabel" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedPeriodEndLabel" xlink:type="simple" />
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedPeriodStartLabel" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedPeriodStartLabel" xlink:type="simple" />
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedTerseLabel" xlink:type="simple" />
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedTotalLabel" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedTotalLabel" xlink:type="simple" />
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/netLabel" xlink:href="http://www.xbrl.org/lrr/role/net-2009-12-16.xsd#netLabel" xlink:type="simple" />
  <link:presentationLink xlink:role="http://www.endo.com/role/AccountsPayableAndAccruedExpenses" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccruedLiabilitiesCurrentAndNoncurrentAbstract" xlink:label="loc_us-gaap_AccruedLiabilitiesCurrentAndNoncurrentAbstract_2AC71D2DD3E956E7B97FD2C8D84ADDB6" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccountsPayableAndAccruedLiabilitiesDisclosureTextBlock" xlink:label="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesDisclosureTextBlock_A4EB4DDB438C58A2B48356297B2B1979" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccruedLiabilitiesCurrentAndNoncurrentAbstract_2AC71D2DD3E956E7B97FD2C8D84ADDB6" xlink:to="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesDisclosureTextBlock_A4EB4DDB438C58A2B48356297B2B1979" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/AccountsPayableAndAccruedExpensesDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccruedLiabilitiesCurrentAndNoncurrentAbstract" xlink:label="loc_us-gaap_AccruedLiabilitiesCurrentAndNoncurrentAbstract_36A923C397F35768A3B90CE0DC003E55" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccountsPayableTradeCurrent" xlink:label="loc_us-gaap_AccountsPayableTradeCurrent_CE86FD92C71D5E4A920C821A39BF8C74" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccruedLiabilitiesCurrentAndNoncurrentAbstract_36A923C397F35768A3B90CE0DC003E55" xlink:to="loc_us-gaap_AccountsPayableTradeCurrent_CE86FD92C71D5E4A920C821A39BF8C74" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_AccruedLiabilitiesReturnsAndAllowances" xlink:label="loc_endp_AccruedLiabilitiesReturnsAndAllowances_3DC7B910981F5718A4057B3A963587AD" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccruedLiabilitiesCurrentAndNoncurrentAbstract_36A923C397F35768A3B90CE0DC003E55" xlink:to="loc_endp_AccruedLiabilitiesReturnsAndAllowances_3DC7B910981F5718A4057B3A963587AD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccruedExchangeFeeRebateCurrent" xlink:label="loc_us-gaap_AccruedExchangeFeeRebateCurrent_C86E6D7CA427558D8D4A51702766316C" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccruedLiabilitiesCurrentAndNoncurrentAbstract_36A923C397F35768A3B90CE0DC003E55" xlink:to="loc_us-gaap_AccruedExchangeFeeRebateCurrent_C86E6D7CA427558D8D4A51702766316C" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_AccruedLiabilitiesChargebacks" xlink:label="loc_endp_AccruedLiabilitiesChargebacks_21E518A6998D5F078A32E4BD3E1D9A94" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccruedLiabilitiesCurrentAndNoncurrentAbstract_36A923C397F35768A3B90CE0DC003E55" xlink:to="loc_endp_AccruedLiabilitiesChargebacks_21E518A6998D5F078A32E4BD3E1D9A94" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_InterestPayableCurrentAndNoncurrent" xlink:label="loc_us-gaap_InterestPayableCurrentAndNoncurrent_F6ECB4B94EF3520F9EF269E589972B4D" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccruedLiabilitiesCurrentAndNoncurrentAbstract_36A923C397F35768A3B90CE0DC003E55" xlink:to="loc_us-gaap_InterestPayableCurrentAndNoncurrent_F6ECB4B94EF3520F9EF269E589972B4D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccruedPayrollTaxesCurrent" xlink:label="loc_us-gaap_AccruedPayrollTaxesCurrent_9C8E3AC10EAB5ABF964B6B2410943DAF" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccruedLiabilitiesCurrentAndNoncurrentAbstract_36A923C397F35768A3B90CE0DC003E55" xlink:to="loc_us-gaap_AccruedPayrollTaxesCurrent_9C8E3AC10EAB5ABF964B6B2410943DAF" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_AccruedRoyaltiesandOtherDistributionPartnerPayablesCurrent" xlink:label="loc_endp_AccruedRoyaltiesandOtherDistributionPartnerPayablesCurrent_C726D68A1F4E54348587F09FFDCCC220" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccruedLiabilitiesCurrentAndNoncurrentAbstract_36A923C397F35768A3B90CE0DC003E55" xlink:to="loc_endp_AccruedRoyaltiesandOtherDistributionPartnerPayablesCurrent_C726D68A1F4E54348587F09FFDCCC220" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationLiabilityCurrent" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationLiabilityCurrent_C759D00B97E9589781C691F0ADE1CBEA" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccruedLiabilitiesCurrentAndNoncurrentAbstract_36A923C397F35768A3B90CE0DC003E55" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationLiabilityCurrent_C759D00B97E9589781C691F0ADE1CBEA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherAccruedLiabilitiesCurrent" xlink:label="loc_us-gaap_OtherAccruedLiabilitiesCurrent_1423A7240F4751ADBF1210FA80F26104" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccruedLiabilitiesCurrentAndNoncurrentAbstract_36A923C397F35768A3B90CE0DC003E55" xlink:to="loc_us-gaap_OtherAccruedLiabilitiesCurrent_1423A7240F4751ADBF1210FA80F26104" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccruedLiabilitiesCurrent" xlink:label="loc_us-gaap_AccruedLiabilitiesCurrent_01CC0EA24AD05C6BBEDC4B07D31D6092" xlink:type="locator" />
    <link:presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccruedLiabilitiesCurrentAndNoncurrentAbstract_36A923C397F35768A3B90CE0DC003E55" xlink:to="loc_us-gaap_AccruedLiabilitiesCurrent_01CC0EA24AD05C6BBEDC4B07D31D6092" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/AccountsPayableAndAccruedExpensesTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccruedLiabilitiesCurrentAndNoncurrentAbstract" xlink:label="loc_us-gaap_AccruedLiabilitiesCurrentAndNoncurrentAbstract_043EE7E81A1E5215A93C588219EC8F0F" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScheduleOfAccountsPayableAndAccruedLiabilitiesTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfAccountsPayableAndAccruedLiabilitiesTableTextBlock_10948E5BFE0955749C9E3E23DA253091" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccruedLiabilitiesCurrentAndNoncurrentAbstract_043EE7E81A1E5215A93C588219EC8F0F" xlink:to="loc_us-gaap_ScheduleOfAccountsPayableAndAccruedLiabilitiesTableTextBlock_10948E5BFE0955749C9E3E23DA253091" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/BasisOfPresentation" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract" xlink:label="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_7002D36B10CF42DE861B1D167C90639C" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureTextBlock" xlink:label="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureTextBlock_431D1309E5824BA5963D1D167C906E0D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_7002D36B10CF42DE861B1D167C90639C" xlink:to="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureTextBlock_431D1309E5824BA5963D1D167C906E0D" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/BasisOfPresentationBasisDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract" xlink:label="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_6BA3CC67409F0C57DB2C09B48DFFF373" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_StatementTable" xlink:label="loc_us-gaap_StatementTable_823051DBEE8F0F156EAF09B48FB89BAC" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_6BA3CC67409F0C57DB2C09B48DFFF373" xlink:to="loc_us-gaap_StatementTable_823051DBEE8F0F156EAF09B48FB89BAC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AdjustmentsForNewAccountingPronouncementsAxis" xlink:label="loc_us-gaap_AdjustmentsForNewAccountingPronouncementsAxis_30770D3DE55FB5DDC1C009B4E3ADFAB6" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_823051DBEE8F0F156EAF09B48FB89BAC" xlink:to="loc_us-gaap_AdjustmentsForNewAccountingPronouncementsAxis_30770D3DE55FB5DDC1C009B4E3ADFAB6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_TypeOfAdoptionMember" xlink:label="loc_us-gaap_TypeOfAdoptionMember_F8CBC510EB1BC361D28509B4E4A2000E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsForNewAccountingPronouncementsAxis_30770D3DE55FB5DDC1C009B4E3ADFAB6" xlink:to="loc_us-gaap_TypeOfAdoptionMember_F8CBC510EB1BC361D28509B4E4A2000E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccountingStandardsUpdate201618Member" xlink:label="loc_us-gaap_AccountingStandardsUpdate201618Member_F0FC2CB72ABD99CC5F4709B5220CF3FE" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfAdoptionMember_F8CBC510EB1BC361D28509B4E4A2000E" xlink:to="loc_us-gaap_AccountingStandardsUpdate201618Member_F0FC2CB72ABD99CC5F4709B5220CF3FE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_StatementLineItems" xlink:label="loc_us-gaap_StatementLineItems_53F749C8753C2BD3B62409B48FB845E7" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_823051DBEE8F0F156EAF09B48FB89BAC" xlink:to="loc_us-gaap_StatementLineItems_53F749C8753C2BD3B62409B48FB845E7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestrictedCashAndCashEquivalents" xlink:label="loc_us-gaap_RestrictedCashAndCashEquivalents_AFF690A253A1E5CEBC2709B4922F89D3" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_53F749C8753C2BD3B62409B48FB845E7" xlink:to="loc_us-gaap_RestrictedCashAndCashEquivalents_AFF690A253A1E5CEBC2709B4922F89D3" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/BasisOfPresentationScheduleOfEffectOfAdoptionOfAsu201618Details" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract" xlink:label="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_D02C2AECCA887199C7B128D483EB08D8" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable" xlink:label="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable_C747E5F12140911312A028D483EBA064" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_D02C2AECCA887199C7B128D483EB08D8" xlink:to="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable_C747E5F12140911312A028D483EBA064" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AdjustmentsForNewAccountingPronouncementsAxis" xlink:label="loc_us-gaap_AdjustmentsForNewAccountingPronouncementsAxis_4F21440A8152275111AE28D483EB931A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable_C747E5F12140911312A028D483EBA064" xlink:to="loc_us-gaap_AdjustmentsForNewAccountingPronouncementsAxis_4F21440A8152275111AE28D483EB931A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_TypeOfAdoptionMember" xlink:label="loc_us-gaap_TypeOfAdoptionMember_B3D8AF0E58A73D8F8AE428D483EBFB27" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsForNewAccountingPronouncementsAxis_4F21440A8152275111AE28D483EB931A" xlink:to="loc_us-gaap_TypeOfAdoptionMember_B3D8AF0E58A73D8F8AE428D483EBFB27" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccountingStandardsUpdate201618Member" xlink:label="loc_us-gaap_AccountingStandardsUpdate201618Member_0319B31D411EA6BE04FD28D483EB79D6" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfAdoptionMember_B3D8AF0E58A73D8F8AE428D483EBFB27" xlink:to="loc_us-gaap_AccountingStandardsUpdate201618Member_0319B31D411EA6BE04FD28D483EB79D6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_StatementScenarioAxis" xlink:label="loc_us-gaap_StatementScenarioAxis_61FCF30766D55823E18428D483EBC47C" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable_C747E5F12140911312A028D483EBA064" xlink:to="loc_us-gaap_StatementScenarioAxis_61FCF30766D55823E18428D483EBC47C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScenarioUnspecifiedDomain" xlink:label="loc_us-gaap_ScenarioUnspecifiedDomain_DFD0D09BE1068536558E28D483EB7696" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementScenarioAxis_61FCF30766D55823E18428D483EBC47C" xlink:to="loc_us-gaap_ScenarioUnspecifiedDomain_DFD0D09BE1068536558E28D483EB7696" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScenarioPreviouslyReportedMember" xlink:label="loc_us-gaap_ScenarioPreviouslyReportedMember_3D71A7E246D29152545628D483EBF2A3" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScenarioUnspecifiedDomain_DFD0D09BE1068536558E28D483EB7696" xlink:to="loc_us-gaap_ScenarioPreviouslyReportedMember_3D71A7E246D29152545628D483EBF2A3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestatementAdjustmentMember" xlink:label="loc_us-gaap_RestatementAdjustmentMember_5D98585F51261DB66CFE28D483EBEDE8" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScenarioUnspecifiedDomain_DFD0D09BE1068536558E28D483EB7696" xlink:to="loc_us-gaap_RestatementAdjustmentMember_5D98585F51261DB66CFE28D483EBEDE8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems" xlink:label="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_2885F7D244B8F024861928D483EBB8C3" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable_C747E5F12140911312A028D483EBA064" xlink:to="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_2885F7D244B8F024861928D483EBB8C3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_1A6855EC1489E1CC456A28D483EBB00D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_2885F7D244B8F024861928D483EBB8C3" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_1A6855EC1489E1CC456A28D483EBB00D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_47FE00A90FACA122DDD328D483ECDEFD" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_2885F7D244B8F024861928D483EBB8C3" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_47FE00A90FACA122DDD328D483ECDEFD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_06E81DCA047BA0A4632428D483ECF80D" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_2885F7D244B8F024861928D483EBB8C3" xlink:to="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_06E81DCA047BA0A4632428D483ECF80D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_EffectOfExchangeRateOnCashAndCashEquivalents" xlink:label="loc_us-gaap_EffectOfExchangeRateOnCashAndCashEquivalents_2A9DFC4E8F40E04C617828D483EC3FB8" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_2885F7D244B8F024861928D483EBB8C3" xlink:to="loc_us-gaap_EffectOfExchangeRateOnCashAndCashEquivalents_2A9DFC4E8F40E04C617828D483EC3FB8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_NetCashProvidedByUsedInDiscontinuedOperations" xlink:label="loc_us-gaap_NetCashProvidedByUsedInDiscontinuedOperations_79E49CF1B231EAE1B1D228D483EC2ACE" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_2885F7D244B8F024861928D483EBB8C3" xlink:to="loc_us-gaap_NetCashProvidedByUsedInDiscontinuedOperations_79E49CF1B231EAE1B1D228D483EC2ACE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease" xlink:label="loc_us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease_2DBF742655CADE8EB6D328D483EC7D17" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_2885F7D244B8F024861928D483EBB8C3" xlink:to="loc_us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease_2DBF742655CADE8EB6D328D483EC7D17" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_39163AC2D31E3DA0CFA828D483EC97B0" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_2885F7D244B8F024861928D483EBB8C3" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_39163AC2D31E3DA0CFA828D483EC97B0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_99B615C18C17AADCE74828D483ECDCFD" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_2885F7D244B8F024861928D483EBB8C3" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_99B615C18C17AADCE74828D483ECDCFD" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/BasisOfPresentationTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract" xlink:label="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_BC6C1208A7B6B26549913C343F439438" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScheduleOfNewAccountingPronouncementsAndChangesInAccountingPrinciplesTextBlock" xlink:label="loc_us-gaap_ScheduleOfNewAccountingPronouncementsAndChangesInAccountingPrinciplesTextBlock_B3BB128DD0BA34B8D49D3C343F444725" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_BC6C1208A7B6B26549913C343F439438" xlink:to="loc_us-gaap_ScheduleOfNewAccountingPronouncementsAndChangesInAccountingPrinciplesTextBlock_B3BB128DD0BA34B8D49D3C343F444725" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/CommitmentsAndContingencies" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_9C700C17F6E41A584138F9E7F6A13911" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureTextBlock" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureTextBlock_A4FB1E5DA1970470D6AFF9E7F6A1FB9B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_9C700C17F6E41A584138F9E7F6A13911" xlink:to="loc_us-gaap_CommitmentsAndContingenciesDisclosureTextBlock_A4FB1E5DA1970470D6AFF9E7F6A1FB9B" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/CommitmentsAndContingenciesNarrativeDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_8EB90102D326137FD5313C55545469A9" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LossContingenciesTable" xlink:label="loc_us-gaap_LossContingenciesTable_95D9C50E39100A24A4E43C5554541C43" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_8EB90102D326137FD5313C55545469A9" xlink:to="loc_us-gaap_LossContingenciesTable_95D9C50E39100A24A4E43C5554541C43" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LitigationStatusAxis" xlink:label="loc_us-gaap_LitigationStatusAxis_D227428284E85FCB73BC3C555454130C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesTable_95D9C50E39100A24A4E43C5554541C43" xlink:to="loc_us-gaap_LitigationStatusAxis_D227428284E85FCB73BC3C555454130C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LitigationStatusDomain" xlink:label="loc_us-gaap_LitigationStatusDomain_7277F43162AB3118EDBE3C5554543F3B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LitigationStatusAxis_D227428284E85FCB73BC3C555454130C" xlink:to="loc_us-gaap_LitigationStatusDomain_7277F43162AB3118EDBE3C5554543F3B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_JudicialRulingMember" xlink:label="loc_us-gaap_JudicialRulingMember_55F59B68617CCC7CC5DF3C5554542AE4" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LitigationStatusDomain_7277F43162AB3118EDBE3C5554543F3B" xlink:to="loc_us-gaap_JudicialRulingMember_55F59B68617CCC7CC5DF3C5554542AE4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.sec.gov/dei/2014/dei-2014-01-31.xsd#dei_LegalEntityAxis" xlink:label="loc_dei_LegalEntityAxis_8EB3D0197192309BCFCD3C5554543FBB" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesTable_95D9C50E39100A24A4E43C5554541C43" xlink:to="loc_dei_LegalEntityAxis_8EB3D0197192309BCFCD3C5554543FBB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.sec.gov/dei/2014/dei-2014-01-31.xsd#dei_EntityDomain" xlink:label="loc_dei_EntityDomain_50502ADDB94B52AB5C963C5554555E80" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_LegalEntityAxis_8EB3D0197192309BCFCD3C5554543FBB" xlink:to="loc_dei_EntityDomain_50502ADDB94B52AB5C963C5554555E80" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_AmericanMedicalSystemsMember" xlink:label="loc_endp_AmericanMedicalSystemsMember_D24BDA9D60A621DF6D703C555455B2F4" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityDomain_50502ADDB94B52AB5C963C5554555E80" xlink:to="loc_endp_AmericanMedicalSystemsMember_D24BDA9D60A621DF6D703C555455B2F4" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_ParPharmaceuticalInc.Member" xlink:label="loc_endp_ParPharmaceuticalInc.Member_2E2C4EAA2CC4A57F67E53C5554554A57" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityDomain_50502ADDB94B52AB5C963C5554555E80" xlink:to="loc_endp_ParPharmaceuticalInc.Member_2E2C4EAA2CC4A57F67E53C5554554A57" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_EndoPharmaceuticalsInc.Member" xlink:label="loc_endp_EndoPharmaceuticalsInc.Member_3AF72AFEA4305FDF5E4A3C5554553C79" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityDomain_50502ADDB94B52AB5C963C5554555E80" xlink:to="loc_endp_EndoPharmaceuticalsInc.Member_3AF72AFEA4305FDF5E4A3C5554553C79" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LitigationCaseAxis" xlink:label="loc_us-gaap_LitigationCaseAxis_3B56ED16E5819014B76A3C55545522E5" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesTable_95D9C50E39100A24A4E43C5554541C43" xlink:to="loc_us-gaap_LitigationCaseAxis_3B56ED16E5819014B76A3C55545522E5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LitigationCaseTypeDomain" xlink:label="loc_us-gaap_LitigationCaseTypeDomain_9CFDF5F7A14B6FF268C33C5554550B42" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LitigationCaseAxis_3B56ED16E5819014B76A3C55545522E5" xlink:to="loc_us-gaap_LitigationCaseTypeDomain_9CFDF5F7A14B6FF268C33C5554550B42" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_VaginalMeshCasesMember" xlink:label="loc_endp_VaginalMeshCasesMember_434AE86FD3FA9A3D69753C555455B724" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LitigationCaseTypeDomain_9CFDF5F7A14B6FF268C33C5554550B42" xlink:to="loc_endp_VaginalMeshCasesMember_434AE86FD3FA9A3D69753C555455B724" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_TestosteroneCasesMember" xlink:label="loc_endp_TestosteroneCasesMember_FF5504C23F14972DF1153C55545554A7" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LitigationCaseTypeDomain_9CFDF5F7A14B6FF268C33C5554550B42" xlink:to="loc_endp_TestosteroneCasesMember_FF5504C23F14972DF1153C55545554A7" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_UnapprovedDrugLitigationMember" xlink:label="loc_endp_UnapprovedDrugLitigationMember_BA762783AF397049BD903C5554558A31" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LitigationCaseTypeDomain_9CFDF5F7A14B6FF268C33C5554550B42" xlink:to="loc_endp_UnapprovedDrugLitigationMember_BA762783AF397049BD903C5554558A31" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_OpioidRelatedMattersMember" xlink:label="loc_endp_OpioidRelatedMattersMember_EA379ED2A55737F25A883C5554551DA6" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LitigationCaseTypeDomain_9CFDF5F7A14B6FF268C33C5554550B42" xlink:to="loc_endp_OpioidRelatedMattersMember_EA379ED2A55737F25A883C5554551DA6" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_PricingMattersCasesMember" xlink:label="loc_endp_PricingMattersCasesMember_4B2531611A4BE5C430693C55545592E9" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LitigationCaseTypeDomain_9CFDF5F7A14B6FF268C33C5554550B42" xlink:to="loc_endp_PricingMattersCasesMember_4B2531611A4BE5C430693C55545592E9" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_LidodermMember" xlink:label="loc_endp_LidodermMember_FC0F926882F9C010890D3C555455C194" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LitigationCaseTypeDomain_9CFDF5F7A14B6FF268C33C5554550B42" xlink:to="loc_endp_LidodermMember_FC0F926882F9C010890D3C555455C194" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_Bierv.EndoInternationalplcetal.Member" xlink:label="loc_endp_Bierv.EndoInternationalplcetal.Member_BE944E64949C6DC6812B3C555455FA61" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LitigationCaseTypeDomain_9CFDF5F7A14B6FF268C33C5554550B42" xlink:to="loc_endp_Bierv.EndoInternationalplcetal.Member_BE944E64949C6DC6812B3C555455FA61" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_VASOSTRICTRelatedMattersMember" xlink:label="loc_endp_VASOSTRICTRelatedMattersMember_BCB7AE989A25C68E184A3C555455675B" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LitigationCaseTypeDomain_9CFDF5F7A14B6FF268C33C5554550B42" xlink:to="loc_endp_VASOSTRICTRelatedMattersMember_BCB7AE989A25C68E184A3C555455675B" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_OpanaMember" xlink:label="loc_endp_OpanaMember_02DB060D2D621921C8533C555455A7F1" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LitigationCaseTypeDomain_9CFDF5F7A14B6FF268C33C5554550B42" xlink:to="loc_endp_OpanaMember_02DB060D2D621921C8533C555455A7F1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_TitleOfIndividualAxis" xlink:label="loc_us-gaap_TitleOfIndividualAxis_56F8738A2CFA31C35CA53C5554555F5F" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesTable_95D9C50E39100A24A4E43C5554541C43" xlink:to="loc_us-gaap_TitleOfIndividualAxis_56F8738A2CFA31C35CA53C5554555F5F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_TitleOfIndividualWithRelationshipToEntityDomain" xlink:label="loc_us-gaap_TitleOfIndividualWithRelationshipToEntityDomain_D0A880B773F624C613C93C55545577B4" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TitleOfIndividualAxis_56F8738A2CFA31C35CA53C5554555F5F" xlink:to="loc_us-gaap_TitleOfIndividualWithRelationshipToEntityDomain_D0A880B773F624C613C93C55545577B4" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_CurrentandFormerDirectorsandOfficersMember" xlink:label="loc_endp_CurrentandFormerDirectorsandOfficersMember_77B8DA117422E91E71C13C555455F468" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TitleOfIndividualWithRelationshipToEntityDomain_D0A880B773F624C613C93C55545577B4" xlink:to="loc_endp_CurrentandFormerDirectorsandOfficersMember_77B8DA117422E91E71C13C555455F468" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SubsequentEventTypeAxis" xlink:label="loc_us-gaap_SubsequentEventTypeAxis_4B845085EA9BD8C91F5D3C5554566F63" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesTable_95D9C50E39100A24A4E43C5554541C43" xlink:to="loc_us-gaap_SubsequentEventTypeAxis_4B845085EA9BD8C91F5D3C5554566F63" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SubsequentEventTypeDomain" xlink:label="loc_us-gaap_SubsequentEventTypeDomain_EE13D4F9073CFC2B27993C555456AA19" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTypeAxis_4B845085EA9BD8C91F5D3C5554566F63" xlink:to="loc_us-gaap_SubsequentEventTypeDomain_EE13D4F9073CFC2B27993C555456AA19" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SubsequentEventMember" xlink:label="loc_us-gaap_SubsequentEventMember_B60A7A1A942765C443AB3C5554565033" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTypeDomain_EE13D4F9073CFC2B27993C555456AA19" xlink:to="loc_us-gaap_SubsequentEventMember_B60A7A1A942765C443AB3C5554565033" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_TrancheAxis" xlink:label="loc_endp_TrancheAxis_1111480206579C2255583C555456FF4D" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesTable_95D9C50E39100A24A4E43C5554541C43" xlink:to="loc_endp_TrancheAxis_1111480206579C2255583C555456FF4D" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_TrancheDomain" xlink:label="loc_endp_TrancheDomain_D0CE88D342DD78D019B03C555456651D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_TrancheAxis_1111480206579C2255583C555456FF4D" xlink:to="loc_endp_TrancheDomain_D0CE88D342DD78D019B03C555456651D" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_Tranche1Member" xlink:label="loc_endp_Tranche1Member_85ECBBEA32C2F9E5FD653C55545605D8" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_TrancheDomain_D0CE88D342DD78D019B03C555456651D" xlink:to="loc_endp_Tranche1Member_85ECBBEA32C2F9E5FD653C55545605D8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LossContingenciesLineItems" xlink:label="loc_us-gaap_LossContingenciesLineItems_168F24F6D397F74971423C5554566F6E" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesTable_95D9C50E39100A24A4E43C5554541C43" xlink:to="loc_us-gaap_LossContingenciesLineItems_168F24F6D397F74971423C5554566F6E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LossContingencyAccrualAtCarryingValue" xlink:label="loc_us-gaap_LossContingencyAccrualAtCarryingValue_3EDD668F23180AAAD74D3C555456B081" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_168F24F6D397F74971423C5554566F6E" xlink:to="loc_us-gaap_LossContingencyAccrualAtCarryingValue_3EDD668F23180AAAD74D3C555456B081" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LossContingencyAccrualProductLiabilityGross" xlink:label="loc_us-gaap_LossContingencyAccrualProductLiabilityGross_E9B6A8799001161EAEE63C55545665D2" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_168F24F6D397F74971423C5554566F6E" xlink:to="loc_us-gaap_LossContingencyAccrualProductLiabilityGross_E9B6A8799001161EAEE63C55545665D2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LossContingencyAccrualCarryingValuePeriodIncreaseDecrease" xlink:label="loc_us-gaap_LossContingencyAccrualCarryingValuePeriodIncreaseDecrease_1F5E753B3E46DECE9D0E3C5554563C4F" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_168F24F6D397F74971423C5554566F6E" xlink:to="loc_us-gaap_LossContingencyAccrualCarryingValuePeriodIncreaseDecrease_1F5E753B3E46DECE9D0E3C5554563C4F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LossContingencyClaimsSettledNumber" xlink:label="loc_us-gaap_LossContingencyClaimsSettledNumber_E4D39AFD6FEF76532B133C555456FF4B" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_168F24F6D397F74971423C5554566F6E" xlink:to="loc_us-gaap_LossContingencyClaimsSettledNumber_E4D39AFD6FEF76532B133C555456FF4B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LossContingencyAccrualCarryingValueCurrent" xlink:label="loc_us-gaap_LossContingencyAccrualCarryingValueCurrent_C87D4F9CD20F6DD3AD943C555456CE42" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_168F24F6D397F74971423C5554566F6E" xlink:to="loc_us-gaap_LossContingencyAccrualCarryingValueCurrent_C87D4F9CD20F6DD3AD943C555456CE42" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LossContingencyAccrualPayments" xlink:label="loc_us-gaap_LossContingencyAccrualPayments_71E9494B64FA961EFF3E3C555456CA18" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_168F24F6D397F74971423C5554566F6E" xlink:to="loc_us-gaap_LossContingencyAccrualPayments_71E9494B64FA961EFF3E3C555456CA18" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_SettlementFunds" xlink:label="loc_endp_SettlementFunds_D3652C881280C26126703C555456966E" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_168F24F6D397F74971423C5554566F6E" xlink:to="loc_endp_SettlementFunds_D3652C881280C26126703C555456966E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LossContingencyPendingClaimsNumber" xlink:label="loc_us-gaap_LossContingencyPendingClaimsNumber_AC405A800FAABF9B6ABD3C555456C1A7" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_168F24F6D397F74971423C5554566F6E" xlink:to="loc_us-gaap_LossContingencyPendingClaimsNumber_AC405A800FAABF9B6ABD3C555456C1A7" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_LossContingencyClaimsFiledByStatesNumber" xlink:label="loc_endp_LossContingencyClaimsFiledByStatesNumber_A44BBAB2EFAE4CE193673C55545699BE" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_168F24F6D397F74971423C5554566F6E" xlink:to="loc_endp_LossContingencyClaimsFiledByStatesNumber_A44BBAB2EFAE4CE193673C55545699BE" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_LossContingencyNumberOfCasesFiledByHospitalsHealthSystemsUnionsWelfareFundsOrOtherThirdParty" xlink:label="loc_endp_LossContingencyNumberOfCasesFiledByHospitalsHealthSystemsUnionsWelfareFundsOrOtherThirdParty_359D17CD766B2EE1407F3C555456D2C6" xlink:type="locator" />
    <link:presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_168F24F6D397F74971423C5554566F6E" xlink:to="loc_endp_LossContingencyNumberOfCasesFiledByHospitalsHealthSystemsUnionsWelfareFundsOrOtherThirdParty_359D17CD766B2EE1407F3C555456D2C6" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_LossContingencyNumberOfCasesAllegingPersonalInjuryAndOrWrongfulDeath" xlink:label="loc_endp_LossContingencyNumberOfCasesAllegingPersonalInjuryAndOrWrongfulDeath_8DEDB17DD79AF19DE0943C5554567A69" xlink:type="locator" />
    <link:presentationArc order="11" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_168F24F6D397F74971423C5554566F6E" xlink:to="loc_endp_LossContingencyNumberOfCasesAllegingPersonalInjuryAndOrWrongfulDeath_8DEDB17DD79AF19DE0943C5554567A69" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_LossContingencyCasesSetForTrialNumber" xlink:label="loc_endp_LossContingencyCasesSetForTrialNumber_E99CA4F94700D69CEAA93C555456F9A7" xlink:type="locator" />
    <link:presentationArc order="12" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_168F24F6D397F74971423C5554566F6E" xlink:to="loc_endp_LossContingencyCasesSetForTrialNumber_E99CA4F94700D69CEAA93C555456F9A7" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_LossContingencyNumberofProductsInvolvedinClaims" xlink:label="loc_endp_LossContingencyNumberofProductsInvolvedinClaims_2C185292B9E757443B9C3C55545666D5" xlink:type="locator" />
    <link:presentationArc order="13" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_168F24F6D397F74971423C5554566F6E" xlink:to="loc_endp_LossContingencyNumberofProductsInvolvedinClaims_2C185292B9E757443B9C3C55545666D5" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_LossContingencyNumberofTranchesforClaims" xlink:label="loc_endp_LossContingencyNumberofTranchesforClaims_9B08CB7BE347FB2754E13C555456ECB6" xlink:type="locator" />
    <link:presentationArc order="14" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_168F24F6D397F74971423C5554566F6E" xlink:to="loc_endp_LossContingencyNumberofTranchesforClaims_9B08CB7BE347FB2754E13C555456ECB6" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_StateAttorneyGeneralsNumber" xlink:label="loc_endp_StateAttorneyGeneralsNumber_AA3A78EA69D4BC8504C83C55545684DA" xlink:type="locator" />
    <link:presentationArc order="15" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_168F24F6D397F74971423C5554566F6E" xlink:to="loc_endp_StateAttorneyGeneralsNumber_AA3A78EA69D4BC8504C83C55545684DA" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_LossContingencyNumberofClaimsConsolidated" xlink:label="loc_endp_LossContingencyNumberofClaimsConsolidated_7E2E34ECE23FFBCA95CA3C555457410A" xlink:type="locator" />
    <link:presentationArc order="16" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_168F24F6D397F74971423C5554566F6E" xlink:to="loc_endp_LossContingencyNumberofClaimsConsolidated_7E2E34ECE23FFBCA95CA3C555457410A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LossContingencyNumberOfDefendants" xlink:label="loc_us-gaap_LossContingencyNumberOfDefendants_58FE4E4772303B4C562F3C555457B773" xlink:type="locator" />
    <link:presentationArc order="17" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_168F24F6D397F74971423C5554566F6E" xlink:to="loc_us-gaap_LossContingencyNumberOfDefendants_58FE4E4772303B4C562F3C555457B773" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_LossContingencyNumberOfProductsAllegedlyManufacturedByPPI" xlink:label="loc_endp_LossContingencyNumberOfProductsAllegedlyManufacturedByPPI_292984F8B2CA11B0E8E33C555457984F" xlink:type="locator" />
    <link:presentationArc order="18" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_168F24F6D397F74971423C5554566F6E" xlink:to="loc_endp_LossContingencyNumberOfProductsAllegedlyManufacturedByPPI_292984F8B2CA11B0E8E33C555457984F" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_LossContingencyNumberOfAdditionalDefendantsNamed" xlink:label="loc_endp_LossContingencyNumberOfAdditionalDefendantsNamed_7CE0CB51A8D4535876333C555457F3D0" xlink:type="locator" />
    <link:presentationArc order="19" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_168F24F6D397F74971423C5554566F6E" xlink:to="loc_endp_LossContingencyNumberOfAdditionalDefendantsNamed_7CE0CB51A8D4535876333C555457F3D0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_GainContingencyPatentsAllegedlyInfringedUponNumber" xlink:label="loc_us-gaap_GainContingencyPatentsAllegedlyInfringedUponNumber_8CCA98BA3B2AD0BA9C1D3C555457094A" xlink:type="locator" />
    <link:presentationArc order="20" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_168F24F6D397F74971423C5554566F6E" xlink:to="loc_us-gaap_GainContingencyPatentsAllegedlyInfringedUponNumber_8CCA98BA3B2AD0BA9C1D3C555457094A" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_LossContingencyNumberOfDefendantsFilingMotionToDismissLackOfPersonalInjuryJurisdiction" xlink:label="loc_endp_LossContingencyNumberOfDefendantsFilingMotionToDismissLackOfPersonalInjuryJurisdiction_D0FB658EE1C381AD93D53C5554573D77" xlink:type="locator" />
    <link:presentationArc order="21" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_168F24F6D397F74971423C5554566F6E" xlink:to="loc_endp_LossContingencyNumberOfDefendantsFilingMotionToDismissLackOfPersonalInjuryJurisdiction_D0FB658EE1C381AD93D53C5554573D77" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_LossContingencyNumberOfDefendantsFilingMotionToDismiss" xlink:label="loc_endp_LossContingencyNumberOfDefendantsFilingMotionToDismiss_6E8805068AA8DD64134E3C555457715B" xlink:type="locator" />
    <link:presentationArc order="22" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_168F24F6D397F74971423C5554566F6E" xlink:to="loc_endp_LossContingencyNumberOfDefendantsFilingMotionToDismiss_6E8805068AA8DD64134E3C555457715B" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_LossContingencyStayOfProceedingsNumberOfDays" xlink:label="loc_endp_LossContingencyStayOfProceedingsNumberOfDays_922F3C2C009BC99AE0C63C561FAC7E2A" xlink:type="locator" />
    <link:presentationArc order="23" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_168F24F6D397F74971423C5554566F6E" xlink:to="loc_endp_LossContingencyStayOfProceedingsNumberOfDays_922F3C2C009BC99AE0C63C561FAC7E2A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_GainContingencyPatentsFoundInfringedUponNumber" xlink:label="loc_us-gaap_GainContingencyPatentsFoundInfringedUponNumber_97852902601DFCCEDFBD3C5554579687" xlink:type="locator" />
    <link:presentationArc order="24" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_168F24F6D397F74971423C5554566F6E" xlink:to="loc_us-gaap_GainContingencyPatentsFoundInfringedUponNumber_97852902601DFCCEDFBD3C5554579687" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_GainContingencyPeriodForWithdrawingGenericProduct" xlink:label="loc_endp_GainContingencyPeriodForWithdrawingGenericProduct_CFDCA18519F61A7D751D3C555457B609" xlink:type="locator" />
    <link:presentationArc order="25" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_168F24F6D397F74971423C5554566F6E" xlink:to="loc_endp_GainContingencyPeriodForWithdrawingGenericProduct_CFDCA18519F61A7D751D3C555457B609" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_GainContingencyNumberOfPostTrialMotions" xlink:label="loc_endp_GainContingencyNumberOfPostTrialMotions_11B93DDF3C82B61200F13C55545726DC" xlink:type="locator" />
    <link:presentationArc order="26" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_168F24F6D397F74971423C5554566F6E" xlink:to="loc_endp_GainContingencyNumberOfPostTrialMotions_11B93DDF3C82B61200F13C55545726DC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LitigationSettlementAmountAwardedFromOtherParty" xlink:label="loc_us-gaap_LitigationSettlementAmountAwardedFromOtherParty_6314DEC4DDCF7D622FB13C555457910C" xlink:type="locator" />
    <link:presentationArc order="27" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_168F24F6D397F74971423C5554566F6E" xlink:to="loc_us-gaap_LitigationSettlementAmountAwardedFromOtherParty_6314DEC4DDCF7D622FB13C555457910C" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_LossContingencyLawsuitFilingPeriod" xlink:label="loc_endp_LossContingencyLawsuitFilingPeriod_FEE82D90A15236135B523C555457D978" xlink:type="locator" />
    <link:presentationArc order="28" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_168F24F6D397F74971423C5554566F6E" xlink:to="loc_endp_LossContingencyLawsuitFilingPeriod_FEE82D90A15236135B523C555457D978" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_LossContingencyStayOfApprovalPeriodHatchWaxmanAct" xlink:label="loc_endp_LossContingencyStayOfApprovalPeriodHatchWaxmanAct_46E096AC7781D2E2D2C63C5554575E0D" xlink:type="locator" />
    <link:presentationArc order="29" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_168F24F6D397F74971423C5554566F6E" xlink:to="loc_endp_LossContingencyStayOfApprovalPeriodHatchWaxmanAct_46E096AC7781D2E2D2C63C5554575E0D" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/CommitmentsAndContingenciesScheduleOfLossContingenciesDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_D17D4CC7ACF52897C858F49DB792EEC5" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LossContingenciesTable" xlink:label="loc_us-gaap_LossContingenciesTable_2B44EEA4A836D299E2D0F49DB792A607" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_D17D4CC7ACF52897C858F49DB792EEC5" xlink:to="loc_us-gaap_LossContingenciesTable_2B44EEA4A836D299E2D0F49DB792A607" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LitigationCaseAxis" xlink:label="loc_us-gaap_LitigationCaseAxis_F285ACAA46936DF8C09BF49DB792E7EC" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesTable_2B44EEA4A836D299E2D0F49DB792A607" xlink:to="loc_us-gaap_LitigationCaseAxis_F285ACAA46936DF8C09BF49DB792E7EC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LitigationCaseTypeDomain" xlink:label="loc_us-gaap_LitigationCaseTypeDomain_9299B2D99F3288EF1DF0F49DB7928507" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LitigationCaseAxis_F285ACAA46936DF8C09BF49DB792E7EC" xlink:to="loc_us-gaap_LitigationCaseTypeDomain_9299B2D99F3288EF1DF0F49DB7928507" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_VaginalMeshCasesMember" xlink:label="loc_endp_VaginalMeshCasesMember_E726EEDB64CA978E1328F49DB7920886" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LitigationCaseTypeDomain_9299B2D99F3288EF1DF0F49DB7928507" xlink:to="loc_endp_VaginalMeshCasesMember_E726EEDB64CA978E1328F49DB7920886" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LossContingenciesByNatureOfContingencyAxis" xlink:label="loc_us-gaap_LossContingenciesByNatureOfContingencyAxis_C35ED3D42E9888E73822F49DB793749A" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesTable_2B44EEA4A836D299E2D0F49DB792A607" xlink:to="loc_us-gaap_LossContingenciesByNatureOfContingencyAxis_C35ED3D42E9888E73822F49DB793749A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LossContingencyNatureDomain" xlink:label="loc_us-gaap_LossContingencyNatureDomain_926D5B13F1C59777EE1CF49DB793A4BE" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesByNatureOfContingencyAxis_C35ED3D42E9888E73822F49DB793749A" xlink:to="loc_us-gaap_LossContingencyNatureDomain_926D5B13F1C59777EE1CF49DB793A4BE" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_ProductLiabilityMember" xlink:label="loc_endp_ProductLiabilityMember_895BC85956B6E32DA3E9F49DB79353A1" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingencyNatureDomain_926D5B13F1C59777EE1CF49DB793A4BE" xlink:to="loc_endp_ProductLiabilityMember_895BC85956B6E32DA3E9F49DB79353A1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LossContingenciesLineItems" xlink:label="loc_us-gaap_LossContingenciesLineItems_AD19B320A1C1F6530AA8F49DB793FBDB" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesTable_2B44EEA4A836D299E2D0F49DB792A607" xlink:to="loc_us-gaap_LossContingenciesLineItems_AD19B320A1C1F6530AA8F49DB793FBDB" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_SettlementFundsRollForward" xlink:label="loc_endp_SettlementFundsRollForward_E03995401BCF2261A269F49DB79385BD" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_AD19B320A1C1F6530AA8F49DB793FBDB" xlink:to="loc_endp_SettlementFundsRollForward_E03995401BCF2261A269F49DB79385BD" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_SettlementFunds" xlink:label="loc_endp_SettlementFunds_8DAA8EEBBA5E7904A24BF49DB79330DC" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_SettlementFundsRollForward_E03995401BCF2261A269F49DB79385BD" xlink:to="loc_endp_SettlementFunds_8DAA8EEBBA5E7904A24BF49DB79330DC" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_SettlementFundsAdditions" xlink:label="loc_endp_SettlementFundsAdditions_6F858C5B638E59432D04F49DB79308D7" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_SettlementFundsRollForward_E03995401BCF2261A269F49DB79385BD" xlink:to="loc_endp_SettlementFundsAdditions_6F858C5B638E59432D04F49DB79308D7" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_SettlementFundsPaymentsToPlaintiffCounselFromQualifiedSettlementFunds" xlink:label="loc_endp_SettlementFundsPaymentsToPlaintiffCounselFromQualifiedSettlementFunds_D941BEDBB1E5C01BD05CF49DB7938CF3" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_SettlementFundsRollForward_E03995401BCF2261A269F49DB79385BD" xlink:to="loc_endp_SettlementFundsPaymentsToPlaintiffCounselFromQualifiedSettlementFunds_D941BEDBB1E5C01BD05CF49DB7938CF3" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_SettlementFundsOther" xlink:label="loc_endp_SettlementFundsOther_70891C396F526A0E723EF49DB793FB26" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_SettlementFundsRollForward_E03995401BCF2261A269F49DB79385BD" xlink:to="loc_endp_SettlementFundsOther_70891C396F526A0E723EF49DB793FB26" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_SettlementFunds" xlink:label="loc_endp_SettlementFunds_56C095D442D70517EB97F49DB7933335" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_SettlementFundsRollForward_E03995401BCF2261A269F49DB79385BD" xlink:to="loc_endp_SettlementFunds_56C095D442D70517EB97F49DB7933335" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LossContingencyAccrualRollForward" xlink:label="loc_us-gaap_LossContingencyAccrualRollForward_5C974B34FE4D507A9556F49DB793D0D4" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_AD19B320A1C1F6530AA8F49DB793FBDB" xlink:to="loc_us-gaap_LossContingencyAccrualRollForward_5C974B34FE4D507A9556F49DB793D0D4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LossContingencyAccrualAtCarryingValue" xlink:label="loc_us-gaap_LossContingencyAccrualAtCarryingValue_DECD665A1EEBD3B5906DF49DB7939E95" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingencyAccrualRollForward_5C974B34FE4D507A9556F49DB793D0D4" xlink:to="loc_us-gaap_LossContingencyAccrualAtCarryingValue_DECD665A1EEBD3B5906DF49DB7939E95" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LossContingencyAccrualProvision" xlink:label="loc_us-gaap_LossContingencyAccrualProvision_D87B9CAC5B12CBDB6BF0F49DB793D22E" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingencyAccrualRollForward_5C974B34FE4D507A9556F49DB793D0D4" xlink:to="loc_us-gaap_LossContingencyAccrualProvision_D87B9CAC5B12CBDB6BF0F49DB793D22E" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_LossContingencyAccrualPaymentsToPlaintiffCounselFromQualifiedSettlementFunds" xlink:label="loc_endp_LossContingencyAccrualPaymentsToPlaintiffCounselFromQualifiedSettlementFunds_080899E525DA1AFE2008F49DB7938965" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingencyAccrualRollForward_5C974B34FE4D507A9556F49DB793D0D4" xlink:to="loc_endp_LossContingencyAccrualPaymentsToPlaintiffCounselFromQualifiedSettlementFunds_080899E525DA1AFE2008F49DB7938965" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_LossContingencyAccrualPaymentsToPlaintiffCounsel" xlink:label="loc_endp_LossContingencyAccrualPaymentsToPlaintiffCounsel_B2B3E5F71881EDFEA2A9F49DB7931075" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingencyAccrualRollForward_5C974B34FE4D507A9556F49DB793D0D4" xlink:to="loc_endp_LossContingencyAccrualPaymentsToPlaintiffCounsel_B2B3E5F71881EDFEA2A9F49DB7931075" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LossContingencyAccrualAtCarryingValue" xlink:label="loc_us-gaap_LossContingencyAccrualAtCarryingValue_AB65813B3BD5633672CDF49DB793D766" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingencyAccrualRollForward_5C974B34FE4D507A9556F49DB793D0D4" xlink:to="loc_us-gaap_LossContingencyAccrualAtCarryingValue_AB65813B3BD5633672CDF49DB793D766" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/CommitmentsAndContingenciesTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_9AEF29C4F8F2D7586FF7F49DB7C4230B" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScheduleOfLossContingenciesByContingencyTextBlock" xlink:label="loc_us-gaap_ScheduleOfLossContingenciesByContingencyTextBlock_0932CC6D379A92704A05F49DB7C470CC" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_9AEF29C4F8F2D7586FF7F49DB7C4230B" xlink:to="loc_us-gaap_ScheduleOfLossContingenciesByContingencyTextBlock_0932CC6D379A92704A05F49DB7C470CC" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/CondensedConsolidatedBalanceSheetsUnaudited" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_StatementOfFinancialPositionAbstract" xlink:label="loc_us-gaap_StatementOfFinancialPositionAbstract_AF2F92A2881A3C21544908CC11CBD0E9" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AssetsAbstract" xlink:label="loc_us-gaap_AssetsAbstract_DAC9478DCF7625931D2908CC11CB6B06" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_AF2F92A2881A3C21544908CC11CBD0E9" xlink:to="loc_us-gaap_AssetsAbstract_DAC9478DCF7625931D2908CC11CB6B06" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AssetsCurrentAbstract" xlink:label="loc_us-gaap_AssetsCurrentAbstract_DD04745264355686BD9E08CC11CBF3F5" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_DAC9478DCF7625931D2908CC11CB6B06" xlink:to="loc_us-gaap_AssetsCurrentAbstract_DD04745264355686BD9E08CC11CBF3F5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_C8F05A573945260C2B6E08CC11CB3ECC" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_DD04745264355686BD9E08CC11CBF3F5" xlink:to="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_C8F05A573945260C2B6E08CC11CB3ECC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestrictedCashCurrent" xlink:label="loc_us-gaap_RestrictedCashCurrent_2A115AF8C3FA0A3F444C08CC11CBA984" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_DD04745264355686BD9E08CC11CBF3F5" xlink:to="loc_us-gaap_RestrictedCashCurrent_2A115AF8C3FA0A3F444C08CC11CBA984" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccountsReceivableNetCurrent" xlink:label="loc_us-gaap_AccountsReceivableNetCurrent_BDF0F0FA2F95E86A841108CC11CBCBC9" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_DD04745264355686BD9E08CC11CBF3F5" xlink:to="loc_us-gaap_AccountsReceivableNetCurrent_BDF0F0FA2F95E86A841108CC11CBCBC9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_InventoryNet" xlink:label="loc_us-gaap_InventoryNet_8BA960428F30A13298FA08CC11CBFB86" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_DD04745264355686BD9E08CC11CBF3F5" xlink:to="loc_us-gaap_InventoryNet_8BA960428F30A13298FA08CC11CBFB86" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_PrepaidExpenseAndOtherAssetsCurrent" xlink:label="loc_us-gaap_PrepaidExpenseAndOtherAssetsCurrent_C336276D833E7B657AA308CC11CBA542" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_DD04745264355686BD9E08CC11CBF3F5" xlink:to="loc_us-gaap_PrepaidExpenseAndOtherAssetsCurrent_C336276D833E7B657AA308CC11CBA542" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeTaxesReceivable" xlink:label="loc_us-gaap_IncomeTaxesReceivable_40D49EA1BDF99DA87C1B08CC11CBBF90" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_DD04745264355686BD9E08CC11CBF3F5" xlink:to="loc_us-gaap_IncomeTaxesReceivable_40D49EA1BDF99DA87C1B08CC11CBBF90" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AssetsCurrent" xlink:label="loc_us-gaap_AssetsCurrent_F456E2E46990942CD78508CC11CBCC1B" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_DD04745264355686BD9E08CC11CBF3F5" xlink:to="loc_us-gaap_AssetsCurrent_F456E2E46990942CD78508CC11CBCC1B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_MarketableSecuritiesNoncurrent" xlink:label="loc_us-gaap_MarketableSecuritiesNoncurrent_9FEEBA730D5F30B85A7F08CC11CB2670" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_DAC9478DCF7625931D2908CC11CB6B06" xlink:to="loc_us-gaap_MarketableSecuritiesNoncurrent_9FEEBA730D5F30B85A7F08CC11CB2670" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_PropertyPlantAndEquipmentNet" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_8CFCECA268868EE4921508CC11CBF69C" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_DAC9478DCF7625931D2908CC11CB6B06" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentNet_8CFCECA268868EE4921508CC11CBF69C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_Goodwill" xlink:label="loc_us-gaap_Goodwill_58E83CAB172F6A1B62F808CC11CB4918" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_DAC9478DCF7625931D2908CC11CB6B06" xlink:to="loc_us-gaap_Goodwill_58E83CAB172F6A1B62F808CC11CB4918" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IntangibleAssetsNetExcludingGoodwill" xlink:label="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_F5A249A849934BB0283608CC11CB4051" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_DAC9478DCF7625931D2908CC11CB6B06" xlink:to="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_F5A249A849934BB0283608CC11CB4051" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DeferredIncomeTaxAssetsNet" xlink:label="loc_us-gaap_DeferredIncomeTaxAssetsNet_A7800C218A1EA70D48D608CC11CB33A1" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_DAC9478DCF7625931D2908CC11CB6B06" xlink:to="loc_us-gaap_DeferredIncomeTaxAssetsNet_A7800C218A1EA70D48D608CC11CB33A1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherAssetsNoncurrent" xlink:label="loc_us-gaap_OtherAssetsNoncurrent_4C5A286D74140B74D82C08CC11CB2A08" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_DAC9478DCF7625931D2908CC11CB6B06" xlink:to="loc_us-gaap_OtherAssetsNoncurrent_4C5A286D74140B74D82C08CC11CB2A08" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_Assets" xlink:label="loc_us-gaap_Assets_D9A2A7D1AAC341D2FBA608CC11CBB583" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_DAC9478DCF7625931D2908CC11CB6B06" xlink:to="loc_us-gaap_Assets_D9A2A7D1AAC341D2FBA608CC11CBB583" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LiabilitiesAndStockholdersEquityAbstract" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_2B9FFEAD3D64004BEB5408CC11CB1BC8" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_AF2F92A2881A3C21544908CC11CBD0E9" xlink:to="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_2B9FFEAD3D64004BEB5408CC11CB1BC8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LiabilitiesCurrentAbstract" xlink:label="loc_us-gaap_LiabilitiesCurrentAbstract_7D1C9D80D9BA32D4B3FD08CC11CB9D52" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_2B9FFEAD3D64004BEB5408CC11CB1BC8" xlink:to="loc_us-gaap_LiabilitiesCurrentAbstract_7D1C9D80D9BA32D4B3FD08CC11CB9D52" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccountsPayableAndAccruedLiabilitiesCurrent" xlink:label="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesCurrent_5EB62F964F75181B3FE408CC11CB5BBE" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_7D1C9D80D9BA32D4B3FD08CC11CB9D52" xlink:to="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesCurrent_5EB62F964F75181B3FE408CC11CB5BBE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LossContingencyAccrualCarryingValueCurrent" xlink:label="loc_us-gaap_LossContingencyAccrualCarryingValueCurrent_04B75039E641FCC7A53A08CC11CBB15C" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_7D1C9D80D9BA32D4B3FD08CC11CB9D52" xlink:to="loc_us-gaap_LossContingencyAccrualCarryingValueCurrent_04B75039E641FCC7A53A08CC11CBB15C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LongTermDebtCurrent" xlink:label="loc_us-gaap_LongTermDebtCurrent_629FC87BF749CF516C0808CC11CB1C8D" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_7D1C9D80D9BA32D4B3FD08CC11CB9D52" xlink:to="loc_us-gaap_LongTermDebtCurrent_629FC87BF749CF516C0808CC11CB1C8D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccruedIncomeTaxesCurrent" xlink:label="loc_us-gaap_AccruedIncomeTaxesCurrent_5A6B99A74592561736FA08CC11CB0E89" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_7D1C9D80D9BA32D4B3FD08CC11CB9D52" xlink:to="loc_us-gaap_AccruedIncomeTaxesCurrent_5A6B99A74592561736FA08CC11CB0E89" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LiabilitiesCurrent" xlink:label="loc_us-gaap_LiabilitiesCurrent_F86389DACB9BCFF5FAFD08CC11CB01C0" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_7D1C9D80D9BA32D4B3FD08CC11CB9D52" xlink:to="loc_us-gaap_LiabilitiesCurrent_F86389DACB9BCFF5FAFD08CC11CB01C0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DeferredIncomeTaxLiabilitiesNet" xlink:label="loc_us-gaap_DeferredIncomeTaxLiabilitiesNet_425AE3191028421C475E08CC11CBD96D" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_2B9FFEAD3D64004BEB5408CC11CB1BC8" xlink:to="loc_us-gaap_DeferredIncomeTaxLiabilitiesNet_425AE3191028421C475E08CC11CBD96D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LongTermDebtNoncurrent" xlink:label="loc_us-gaap_LongTermDebtNoncurrent_950037B927BDCD53456E08CC11CB8871" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_2B9FFEAD3D64004BEB5408CC11CB1BC8" xlink:to="loc_us-gaap_LongTermDebtNoncurrent_950037B927BDCD53456E08CC11CB8871" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LossContingencyAccrualCarryingValueNoncurrent" xlink:label="loc_us-gaap_LossContingencyAccrualCarryingValueNoncurrent_738267B4A37AC9F039A508CC11CB2AD2" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_2B9FFEAD3D64004BEB5408CC11CB1BC8" xlink:to="loc_us-gaap_LossContingencyAccrualCarryingValueNoncurrent_738267B4A37AC9F039A508CC11CB2AD2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherLiabilitiesNoncurrent" xlink:label="loc_us-gaap_OtherLiabilitiesNoncurrent_E1A8D312225886D498DF08CC11CB3654" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_2B9FFEAD3D64004BEB5408CC11CB1BC8" xlink:to="loc_us-gaap_OtherLiabilitiesNoncurrent_E1A8D312225886D498DF08CC11CB3654" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CommitmentsAndContingencies" xlink:label="loc_us-gaap_CommitmentsAndContingencies_275FB773FB68EA6B447608CC11CB389E" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_2B9FFEAD3D64004BEB5408CC11CB1BC8" xlink:to="loc_us-gaap_CommitmentsAndContingencies_275FB773FB68EA6B447608CC11CB389E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterestAbstract" xlink:label="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterestAbstract_877229D3440CC7D56C9A08CC11CB70A6" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_2B9FFEAD3D64004BEB5408CC11CB1BC8" xlink:to="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterestAbstract_877229D3440CC7D56C9A08CC11CB70A6" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_EuroDeferredStockValueIssued" xlink:label="loc_endp_EuroDeferredStockValueIssued_B1E7248CE118E9ECADD708CC11CB8015" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterestAbstract_877229D3440CC7D56C9A08CC11CB70A6" xlink:to="loc_endp_EuroDeferredStockValueIssued_B1E7248CE118E9ECADD708CC11CB8015" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CommonStockValue" xlink:label="loc_us-gaap_CommonStockValue_16E38CCF73662F26C21D08CC11CB5E2D" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterestAbstract_877229D3440CC7D56C9A08CC11CB70A6" xlink:to="loc_us-gaap_CommonStockValue_16E38CCF73662F26C21D08CC11CB5E2D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AdditionalPaidInCapital" xlink:label="loc_us-gaap_AdditionalPaidInCapital_D67AEA414CB1494698DD08CC11CBFF22" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterestAbstract_877229D3440CC7D56C9A08CC11CB70A6" xlink:to="loc_us-gaap_AdditionalPaidInCapital_D67AEA414CB1494698DD08CC11CBFF22" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RetainedEarningsAccumulatedDeficit" xlink:label="loc_us-gaap_RetainedEarningsAccumulatedDeficit_ACEC4C87CA03FFDA8D7A08CC11CB31AC" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterestAbstract_877229D3440CC7D56C9A08CC11CB70A6" xlink:to="loc_us-gaap_RetainedEarningsAccumulatedDeficit_ACEC4C87CA03FFDA8D7A08CC11CB31AC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_0237247479EF63FDAE4908CC11CBD220" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterestAbstract_877229D3440CC7D56C9A08CC11CB70A6" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_0237247479EF63FDAE4908CC11CBD220" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest" xlink:label="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest_8BD979132E615A5238B608CC11CBCDD8" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterestAbstract_877229D3440CC7D56C9A08CC11CB70A6" xlink:to="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest_8BD979132E615A5238B608CC11CBCDD8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LiabilitiesAndStockholdersEquity" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquity_6F5ED9D0452C947B88C408CC11CBC638" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_2B9FFEAD3D64004BEB5408CC11CB1BC8" xlink:to="loc_us-gaap_LiabilitiesAndStockholdersEquity_6F5ED9D0452C947B88C408CC11CBC638" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/CondensedConsolidatedBalanceSheetsUnauditedParenthetical" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_StatementOfFinancialPositionAbstract" xlink:label="loc_us-gaap_StatementOfFinancialPositionAbstract_AF74745C6738B0222BDFDF49C75451A6" xlink:type="locator" />
    <link:loc xlink:href="endp-20180331.xsd#endp_EuroDeferredSharesParorStatedValuePerShare" xlink:label="loc_endp_EuroDeferredSharesParorStatedValuePerShare_DACD0502E785B9D6DBB1DF49C754B5B5" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_AF74745C6738B0222BDFDF49C75451A6" xlink:to="loc_endp_EuroDeferredSharesParorStatedValuePerShare_DACD0502E785B9D6DBB1DF49C754B5B5" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_EuroDeferredSharesSharesAuthorized" xlink:label="loc_endp_EuroDeferredSharesSharesAuthorized_22F9FF3ECE8CA79ACA96DF49C7548F10" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_AF74745C6738B0222BDFDF49C75451A6" xlink:to="loc_endp_EuroDeferredSharesSharesAuthorized_22F9FF3ECE8CA79ACA96DF49C7548F10" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_EuroDeferredSharesSharesIssued" xlink:label="loc_endp_EuroDeferredSharesSharesIssued_54757072E1B789195925DF49C75496D4" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_AF74745C6738B0222BDFDF49C75451A6" xlink:to="loc_endp_EuroDeferredSharesSharesIssued_54757072E1B789195925DF49C75496D4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CommonStockParOrStatedValuePerShare" xlink:label="loc_us-gaap_CommonStockParOrStatedValuePerShare_6C5BDE996F7EB00C27AEDF49C754C826" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_AF74745C6738B0222BDFDF49C75451A6" xlink:to="loc_us-gaap_CommonStockParOrStatedValuePerShare_6C5BDE996F7EB00C27AEDF49C754C826" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CommonStockSharesAuthorized" xlink:label="loc_us-gaap_CommonStockSharesAuthorized_C51533BD39F70FB37DA8DF49C754E3EA" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_AF74745C6738B0222BDFDF49C75451A6" xlink:to="loc_us-gaap_CommonStockSharesAuthorized_C51533BD39F70FB37DA8DF49C754E3EA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CommonStockSharesIssued" xlink:label="loc_us-gaap_CommonStockSharesIssued_5189AE4DC6FECCA27792DF49C754425A" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_AF74745C6738B0222BDFDF49C75451A6" xlink:to="loc_us-gaap_CommonStockSharesIssued_5189AE4DC6FECCA27792DF49C754425A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CommonStockSharesOutstanding" xlink:label="loc_us-gaap_CommonStockSharesOutstanding_799A9239C34444F885A8DF49C754EC79" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_AF74745C6738B0222BDFDF49C75451A6" xlink:to="loc_us-gaap_CommonStockSharesOutstanding_799A9239C34444F885A8DF49C754EC79" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/CondensedConsolidatedStatementsOfCashFlowsUnaudited" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_StatementOfCashFlowsAbstract" xlink:label="loc_us-gaap_StatementOfCashFlowsAbstract_DB939C99A485644320603BE694F53A87" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_1667CA1FBED67C18C37A3BE694F59E99" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_DB939C99A485644320603BE694F53A87" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_1667CA1FBED67C18C37A3BE694F59E99" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_NetIncomeLoss" xlink:label="loc_us-gaap_NetIncomeLoss_FB678EF513626CA4329C3BE694F5DCB5" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2009/role/netLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_1667CA1FBED67C18C37A3BE694F59E99" xlink:to="loc_us-gaap_NetIncomeLoss_FB678EF513626CA4329C3BE694F5DCB5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract" xlink:label="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_6FEF73CF0E96AAB61AB13BE694F5FEC3" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_1667CA1FBED67C18C37A3BE694F59E99" xlink:to="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_6FEF73CF0E96AAB61AB13BE694F5FEC3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DepreciationAndAmortization" xlink:label="loc_us-gaap_DepreciationAndAmortization_B56F700A09884C5F3D503BE694F538A7" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_6FEF73CF0E96AAB61AB13BE694F5FEC3" xlink:to="loc_us-gaap_DepreciationAndAmortization_B56F700A09884C5F3D503BE694F538A7" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_InventoryStepUp" xlink:label="loc_endp_InventoryStepUp_B43561DBB6DFB7A08C8B3BE694F58478" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_6FEF73CF0E96AAB61AB13BE694F5FEC3" xlink:to="loc_endp_InventoryStepUp_B43561DBB6DFB7A08C8B3BE694F58478" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ShareBasedCompensation" xlink:label="loc_us-gaap_ShareBasedCompensation_DBF8C7794E814CF875C63BE694F5BC5B" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_6FEF73CF0E96AAB61AB13BE694F5FEC3" xlink:to="loc_us-gaap_ShareBasedCompensation_DBF8C7794E814CF875C63BE694F5BC5B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AmortizationOfFinancingCostsAndDiscounts" xlink:label="loc_us-gaap_AmortizationOfFinancingCostsAndDiscounts_702C21223149EC48D9003BE694F5B1B4" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_6FEF73CF0E96AAB61AB13BE694F5FEC3" xlink:to="loc_us-gaap_AmortizationOfFinancingCostsAndDiscounts_702C21223149EC48D9003BE694F5B1B4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DeferredIncomeTaxesAndTaxCredits" xlink:label="loc_us-gaap_DeferredIncomeTaxesAndTaxCredits_0D6B2511CDD38B9E9ECD3BE694F51BB4" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_6FEF73CF0E96AAB61AB13BE694F5FEC3" xlink:to="loc_us-gaap_DeferredIncomeTaxesAndTaxCredits_0D6B2511CDD38B9E9ECD3BE694F51BB4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1_A4E564FB87D6CCBA9D7F3BE694F52E2F" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_6FEF73CF0E96AAB61AB13BE694F5FEC3" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1_A4E564FB87D6CCBA9D7F3BE694F52E2F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AssetImpairmentCharges" xlink:label="loc_us-gaap_AssetImpairmentCharges_05CCBB9A706C5EA18AC03BE694F5F5E4" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_6FEF73CF0E96AAB61AB13BE694F5FEC3" xlink:to="loc_us-gaap_AssetImpairmentCharges_05CCBB9A706C5EA18AC03BE694F5F5E4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_GainLossOnSaleOfBusiness" xlink:label="loc_us-gaap_GainLossOnSaleOfBusiness_E2C575751BDCD83FB0793BE694F506D3" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_6FEF73CF0E96AAB61AB13BE694F5FEC3" xlink:to="loc_us-gaap_GainLossOnSaleOfBusiness_E2C575751BDCD83FB0793BE694F506D3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncreaseDecreaseInOperatingCapitalAbstract" xlink:label="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_C86F6033B012278E4D0A3BE694F5DD87" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_6FEF73CF0E96AAB61AB13BE694F5FEC3" xlink:to="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_C86F6033B012278E4D0A3BE694F5DD87" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncreaseDecreaseInAccountsReceivable" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsReceivable_8970FF12D8FC2EC0CF1D3BE694F5A766" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_C86F6033B012278E4D0A3BE694F5DD87" xlink:to="loc_us-gaap_IncreaseDecreaseInAccountsReceivable_8970FF12D8FC2EC0CF1D3BE694F5A766" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncreaseDecreaseInInventories" xlink:label="loc_us-gaap_IncreaseDecreaseInInventories_2FBBE54F2636558A03033BE694F5BE09" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_C86F6033B012278E4D0A3BE694F5DD87" xlink:to="loc_us-gaap_IncreaseDecreaseInInventories_2FBBE54F2636558A03033BE694F5BE09" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets" xlink:label="loc_us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets_CBFE33F52761F9693F623BE694F57933" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_C86F6033B012278E4D0A3BE694F5DD87" xlink:to="loc_us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets_CBFE33F52761F9693F623BE694F57933" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities_E5640219BD23FB3210A13BE694F50A0D" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_C86F6033B012278E4D0A3BE694F5DD87" xlink:to="loc_us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities_E5640219BD23FB3210A13BE694F50A0D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncreaseDecreaseInIncomeTaxesPayableNetOfIncomeTaxesReceivable" xlink:label="loc_us-gaap_IncreaseDecreaseInIncomeTaxesPayableNetOfIncomeTaxesReceivable_2AF4F4426FCED81489103BE698CB7431" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_C86F6033B012278E4D0A3BE694F5DD87" xlink:to="loc_us-gaap_IncreaseDecreaseInIncomeTaxesPayableNetOfIncomeTaxesReceivable_2AF4F4426FCED81489103BE698CB7431" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_38EEB2C4A3C455E3925C3BE694F566F1" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_1667CA1FBED67C18C37A3BE694F59E99" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_38EEB2C4A3C455E3925C3BE694F566F1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_CB26A1E985AC1D6BC9833BE694F55C35" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_DB939C99A485644320603BE694F53A87" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_CB26A1E985AC1D6BC9833BE694F55C35" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_PaymentsToAcquirePropertyPlantAndEquipment" xlink:label="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_9A77373FAA1F7B0A3B2A3BE694F5E791" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_CB26A1E985AC1D6BC9833BE694F55C35" xlink:to="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_9A77373FAA1F7B0A3B2A3BE694F5E791" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_InterestPaidCapitalized" xlink:label="loc_us-gaap_InterestPaidCapitalized_234D3E13D77F50601F433BE694F5B8B6" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_CB26A1E985AC1D6BC9833BE694F55C35" xlink:to="loc_us-gaap_InterestPaidCapitalized_234D3E13D77F50601F433BE694F5B8B6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ProceedsFromDivestitureOfBusinesses" xlink:label="loc_us-gaap_ProceedsFromDivestitureOfBusinesses_DCA4900E5DAE532F21A23BE694F5257C" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_CB26A1E985AC1D6BC9833BE694F55C35" xlink:to="loc_us-gaap_ProceedsFromDivestitureOfBusinesses_DCA4900E5DAE532F21A23BE694F5257C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_PaymentsForProceedsFromOtherInvestingActivities" xlink:label="loc_us-gaap_PaymentsForProceedsFromOtherInvestingActivities_781889D54A489E26BE203BE694F53CB7" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_CB26A1E985AC1D6BC9833BE694F55C35" xlink:to="loc_us-gaap_PaymentsForProceedsFromOtherInvestingActivities_781889D54A489E26BE203BE694F53CB7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_580AA87DE583B30AB5D73BE694F5E10B" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_CB26A1E985AC1D6BC9833BE694F55C35" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_580AA87DE583B30AB5D73BE694F5E10B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_0800044896DBB22CBA113BE694F5B752" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_DB939C99A485644320603BE694F53A87" xlink:to="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_0800044896DBB22CBA113BE694F5B752" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RepaymentsOfOtherLongTermDebt" xlink:label="loc_us-gaap_RepaymentsOfOtherLongTermDebt_DC8E1A9D5ACF02110F303BE694F5DAF1" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_0800044896DBB22CBA113BE694F5B752" xlink:to="loc_us-gaap_RepaymentsOfOtherLongTermDebt_DC8E1A9D5ACF02110F303BE694F5DAF1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RepaymentsOfDebt" xlink:label="loc_us-gaap_RepaymentsOfDebt_D5854D25AB262AC564843BE694F52F58" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_0800044896DBB22CBA113BE694F5B752" xlink:to="loc_us-gaap_RepaymentsOfDebt_D5854D25AB262AC564843BE694F52F58" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_PaymentForContingentConsiderationLiabilityFinancingActivities" xlink:label="loc_us-gaap_PaymentForContingentConsiderationLiabilityFinancingActivities_1C0A584F992FA3F5CE2B3BE694F53C3E" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_0800044896DBB22CBA113BE694F5B752" xlink:to="loc_us-gaap_PaymentForContingentConsiderationLiabilityFinancingActivities_1C0A584F992FA3F5CE2B3BE694F53C3E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_PaymentsRelatedToTaxWithholdingForShareBasedCompensation" xlink:label="loc_us-gaap_PaymentsRelatedToTaxWithholdingForShareBasedCompensation_E99472CA5363C2BDCF213BE694F52344" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_0800044896DBB22CBA113BE694F5B752" xlink:to="loc_us-gaap_PaymentsRelatedToTaxWithholdingForShareBasedCompensation_E99472CA5363C2BDCF213BE694F52344" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_18AEF370D29EBC593CD03BE694F5F6C0" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_0800044896DBB22CBA113BE694F5B752" xlink:to="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_18AEF370D29EBC593CD03BE694F5F6C0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_EffectOfExchangeRateOnCashAndCashEquivalents" xlink:label="loc_us-gaap_EffectOfExchangeRateOnCashAndCashEquivalents_56C5DB1281752BE187543BE694F5D687" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_DB939C99A485644320603BE694F53A87" xlink:to="loc_us-gaap_EffectOfExchangeRateOnCashAndCashEquivalents_56C5DB1281752BE187543BE694F5D687" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_NetCashProvidedByUsedInDiscontinuedOperations" xlink:label="loc_us-gaap_NetCashProvidedByUsedInDiscontinuedOperations_6491DA5C4F321CF32F073BE694F5B701" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_DB939C99A485644320603BE694F53A87" xlink:to="loc_us-gaap_NetCashProvidedByUsedInDiscontinuedOperations_6491DA5C4F321CF32F073BE694F5B701" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_246D24059B8F3CA291BC3BE694F5B5CB" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_DB939C99A485644320603BE694F53A87" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_246D24059B8F3CA291BC3BE694F5B5CB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_7F2A4A0A29EE34ED30B33BE694F52FD0" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_DB939C99A485644320603BE694F53A87" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_7F2A4A0A29EE34ED30B33BE694F52FD0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_6D0401564658F3E2C0473BE694F57CF6" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_DB939C99A485644320603BE694F53A87" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_6D0401564658F3E2C0473BE694F57CF6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SupplementalCashFlowInformationAbstract" xlink:label="loc_us-gaap_SupplementalCashFlowInformationAbstract_AC8825F6FCBF62D7958D3BE694F5DFC6" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_DB939C99A485644320603BE694F53A87" xlink:to="loc_us-gaap_SupplementalCashFlowInformationAbstract_AC8825F6FCBF62D7958D3BE694F5DFC6" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_SettlementFundsAdditions" xlink:label="loc_endp_SettlementFundsAdditions_354FCB426E95851AFE7C3BE694F5A2E4" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SupplementalCashFlowInformationAbstract_AC8825F6FCBF62D7958D3BE694F5DFC6" xlink:to="loc_endp_SettlementFundsAdditions_354FCB426E95851AFE7C3BE694F5A2E4" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_SettlementFundsPayments" xlink:label="loc_endp_SettlementFundsPayments_C5290D536446A645A9303BE694F50191" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SupplementalCashFlowInformationAbstract_AC8825F6FCBF62D7958D3BE694F5DFC6" xlink:to="loc_endp_SettlementFundsPayments_C5290D536446A645A9303BE694F50191" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_OtherPaymentsForLegalSettlements" xlink:label="loc_endp_OtherPaymentsForLegalSettlements_4F719ACA4D57679654EF3BE694F56FA5" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SupplementalCashFlowInformationAbstract_AC8825F6FCBF62D7958D3BE694F5DFC6" xlink:to="loc_endp_OtherPaymentsForLegalSettlements_4F719ACA4D57679654EF3BE694F56FA5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CashFlowNoncashInvestingAndFinancingActivitiesDisclosureAbstract" xlink:label="loc_us-gaap_CashFlowNoncashInvestingAndFinancingActivitiesDisclosureAbstract_F38F00B716DE3C99D7D43BE694F58623" xlink:type="locator" />
    <link:presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_DB939C99A485644320603BE694F53A87" xlink:to="loc_us-gaap_CashFlowNoncashInvestingAndFinancingActivitiesDisclosureAbstract_F38F00B716DE3C99D7D43BE694F58623" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CapitalExpendituresIncurredButNotYetPaid" xlink:label="loc_us-gaap_CapitalExpendituresIncurredButNotYetPaid_FEB4D442987F7C6580503BE694F5A56B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashFlowNoncashInvestingAndFinancingActivitiesDisclosureAbstract_F38F00B716DE3C99D7D43BE694F58623" xlink:to="loc_us-gaap_CapitalExpendituresIncurredButNotYetPaid_FEB4D442987F7C6580503BE694F5A56B" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/CondensedConsolidatedStatementsOfComprehensiveLossUnaudited" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract" xlink:label="loc_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract_74B1F7FEB7192708BBDF2C6DCC1FD337" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_NetIncomeLoss" xlink:label="loc_us-gaap_NetIncomeLoss_7AF20BE259AD806791022C6DD02CABE7" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2009/role/netLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract_74B1F7FEB7192708BBDF2C6DCC1FD337" xlink:to="loc_us-gaap_NetIncomeLoss_7AF20BE259AD806791022C6DD02CABE7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTaxPeriodIncreaseDecreaseAbstract" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPeriodIncreaseDecreaseAbstract_E664F39E8765309D2AF92C6DCC23A37F" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract_74B1F7FEB7192708BBDF2C6DCC1FD337" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPeriodIncreaseDecreaseAbstract_E664F39E8765309D2AF92C6DCC23A37F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherComprehensiveIncomeAvailableForSaleSecuritiesAdjustmentNetOfTaxPeriodIncreaseDecreaseAbstract" xlink:label="loc_us-gaap_OtherComprehensiveIncomeAvailableForSaleSecuritiesAdjustmentNetOfTaxPeriodIncreaseDecreaseAbstract_21018E471BEBFED37BC82C6DCC23AE37" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPeriodIncreaseDecreaseAbstract_E664F39E8765309D2AF92C6DCC23A37F" xlink:to="loc_us-gaap_OtherComprehensiveIncomeAvailableForSaleSecuritiesAdjustmentNetOfTaxPeriodIncreaseDecreaseAbstract_21018E471BEBFED37BC82C6DCC23AE37" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax" xlink:label="loc_us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax_8F167BFDA801D9C5E9392C6DCC23EC7D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherComprehensiveIncomeAvailableForSaleSecuritiesAdjustmentNetOfTaxPeriodIncreaseDecreaseAbstract_21018E471BEBFED37BC82C6DCC23AE37" xlink:to="loc_us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax_8F167BFDA801D9C5E9392C6DCC23EC7D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossReclassificationAdjustmentFromAOCIForSaleOfSecuritiesNetOfTax" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossReclassificationAdjustmentFromAOCIForSaleOfSecuritiesNetOfTax_351BAE1469BD6B4C29022C6DCC23CBA4" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherComprehensiveIncomeAvailableForSaleSecuritiesAdjustmentNetOfTaxPeriodIncreaseDecreaseAbstract_21018E471BEBFED37BC82C6DCC23AE37" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossReclassificationAdjustmentFromAOCIForSaleOfSecuritiesNetOfTax_351BAE1469BD6B4C29022C6DCC23CBA4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax_A334A51B6054C3A6FD542C6DCC23B8EC" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherComprehensiveIncomeAvailableForSaleSecuritiesAdjustmentNetOfTaxPeriodIncreaseDecreaseAbstract_21018E471BEBFED37BC82C6DCC23AE37" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax_A334A51B6054C3A6FD542C6DCC23B8EC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPeriodIncreaseDecreaseAbstract" xlink:label="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPeriodIncreaseDecreaseAbstract_9235DB70FC2FF7E83A762C6DCC239C80" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPeriodIncreaseDecreaseAbstract_E664F39E8765309D2AF92C6DCC23A37F" xlink:to="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPeriodIncreaseDecreaseAbstract_9235DB70FC2FF7E83A762C6DCC239C80" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationGainLossArisingDuringPeriodNetOfTax" xlink:label="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationGainLossArisingDuringPeriodNetOfTax_4E1804EA0BE8FE4B28B12C6DCC2339B5" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPeriodIncreaseDecreaseAbstract_9235DB70FC2FF7E83A762C6DCC239C80" xlink:to="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationGainLossArisingDuringPeriodNetOfTax_4E1804EA0BE8FE4B28B12C6DCC2339B5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationReclassificationAdjustmentFromAOCIRealizedUponSaleOrLiquidationNetOfTax" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationReclassificationAdjustmentFromAOCIRealizedUponSaleOrLiquidationNetOfTax_6DD1D3E38DEAC88435962C6DCC239648" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPeriodIncreaseDecreaseAbstract_9235DB70FC2FF7E83A762C6DCC239C80" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationReclassificationAdjustmentFromAOCIRealizedUponSaleOrLiquidationNetOfTax_6DD1D3E38DEAC88435962C6DCC239648" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax_35BC46EF87DD417208822C6DCC2348CD" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPeriodIncreaseDecreaseAbstract_9235DB70FC2FF7E83A762C6DCC239C80" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax_35BC46EF87DD417208822C6DCC2348CD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTax" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax_EC05F08A617201FCDBFE2C6DCC241E7B" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPeriodIncreaseDecreaseAbstract_E664F39E8765309D2AF92C6DCC23A37F" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax_EC05F08A617201FCDBFE2C6DCC241E7B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ComprehensiveIncomeNetOfTax" xlink:label="loc_us-gaap_ComprehensiveIncomeNetOfTax_71FE5FB93D93221D52612C6DCC2407A7" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract_74B1F7FEB7192708BBDF2C6DCC1FD337" xlink:to="loc_us-gaap_ComprehensiveIncomeNetOfTax_71FE5FB93D93221D52612C6DCC2407A7" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/CondensedConsolidatedStatementsOfOperationsUnaudited" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeStatementAbstract" xlink:label="loc_us-gaap_IncomeStatementAbstract_DAC662735372F544509D3B7F1FD80F28" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_Revenues" xlink:label="loc_us-gaap_Revenues_EDB2DB503F263DAC24B13B7F1FD877E8" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_DAC662735372F544509D3B7F1FD80F28" xlink:to="loc_us-gaap_Revenues_EDB2DB503F263DAC24B13B7F1FD877E8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CostsAndExpensesAbstract" xlink:label="loc_us-gaap_CostsAndExpensesAbstract_B25D5AE53284CCE5A12D3B7F1FD82207" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_DAC662735372F544509D3B7F1FD80F28" xlink:to="loc_us-gaap_CostsAndExpensesAbstract_B25D5AE53284CCE5A12D3B7F1FD82207" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CostOfRevenue" xlink:label="loc_us-gaap_CostOfRevenue_47234C52B228F8CECB1A3B7F1FD8F333" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_B25D5AE53284CCE5A12D3B7F1FD82207" xlink:to="loc_us-gaap_CostOfRevenue_47234C52B228F8CECB1A3B7F1FD8F333" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SellingGeneralAndAdministrativeExpense" xlink:label="loc_us-gaap_SellingGeneralAndAdministrativeExpense_57DBB697737F56782C743B7F1FD8DDC2" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_B25D5AE53284CCE5A12D3B7F1FD82207" xlink:to="loc_us-gaap_SellingGeneralAndAdministrativeExpense_57DBB697737F56782C743B7F1FD8DDC2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ResearchAndDevelopmentExpense" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpense_0EB9551636AF5716ABD33B7F1FD87E14" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_B25D5AE53284CCE5A12D3B7F1FD82207" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpense_0EB9551636AF5716ABD33B7F1FD87E14" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LegalFees" xlink:label="loc_us-gaap_LegalFees_5339FB66F6F6484CA7F33B7F1FD83375" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_B25D5AE53284CCE5A12D3B7F1FD82207" xlink:to="loc_us-gaap_LegalFees_5339FB66F6F6484CA7F33B7F1FD83375" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AssetImpairmentCharges" xlink:label="loc_us-gaap_AssetImpairmentCharges_D2B99509C808024D64883B7F1FD89AD7" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_B25D5AE53284CCE5A12D3B7F1FD82207" xlink:to="loc_us-gaap_AssetImpairmentCharges_D2B99509C808024D64883B7F1FD89AD7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessCombinationAcquisitionRelatedCosts" xlink:label="loc_us-gaap_BusinessCombinationAcquisitionRelatedCosts_7439E9DF114DB7792DBA3B7F1FD886F1" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_B25D5AE53284CCE5A12D3B7F1FD82207" xlink:to="loc_us-gaap_BusinessCombinationAcquisitionRelatedCosts_7439E9DF114DB7792DBA3B7F1FD886F1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OperatingIncomeLoss" xlink:label="loc_us-gaap_OperatingIncomeLoss_2D2838688389E50C54553B7F1FD87536" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_DAC662735372F544509D3B7F1FD80F28" xlink:to="loc_us-gaap_OperatingIncomeLoss_2D2838688389E50C54553B7F1FD87536" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_InterestIncomeExpenseNet" xlink:label="loc_us-gaap_InterestIncomeExpenseNet_7CC8A8BF1B0C94E81E773B7F1FD82CFB" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_DAC662735372F544509D3B7F1FD80F28" xlink:to="loc_us-gaap_InterestIncomeExpenseNet_7CC8A8BF1B0C94E81E773B7F1FD82CFB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_NonoperatingIncomeExpense" xlink:label="loc_us-gaap_NonoperatingIncomeExpense_5C3BEFECA54FD17AC7913B7F1FD865D7" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_DAC662735372F544509D3B7F1FD80F28" xlink:to="loc_us-gaap_NonoperatingIncomeExpense_5C3BEFECA54FD17AC7913B7F1FD865D7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_FBD3830B71AB990BE8E13B7F1FD8827A" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_DAC662735372F544509D3B7F1FD80F28" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_FBD3830B71AB990BE8E13B7F1FD8827A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeTaxExpenseBenefit" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_EF8D5A298278072534093B7F1FD8CC46" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_DAC662735372F544509D3B7F1FD80F28" xlink:to="loc_us-gaap_IncomeTaxExpenseBenefit_EF8D5A298278072534093B7F1FD8CC46" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsIncludingPortionAttributableToNoncontrollingInterest" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsIncludingPortionAttributableToNoncontrollingInterest_FC30FE5E6A546229A6693B7F1FD86833" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_DAC662735372F544509D3B7F1FD80F28" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsIncludingPortionAttributableToNoncontrollingInterest_FC30FE5E6A546229A6693B7F1FD86833" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTax" xlink:label="loc_us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTax_9EB7329D8A6B80823F793B7F1FD87AC0" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_DAC662735372F544509D3B7F1FD80F28" xlink:to="loc_us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTax_9EB7329D8A6B80823F793B7F1FD87AC0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_NetIncomeLoss" xlink:label="loc_us-gaap_NetIncomeLoss_BDBE7B3BA76E3A333E0F3B7F1FD88079" xlink:type="locator" />
    <link:presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_DAC662735372F544509D3B7F1FD80F28" xlink:to="loc_us-gaap_NetIncomeLoss_BDBE7B3BA76E3A333E0F3B7F1FD88079" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_EarningsPerShareBasicAbstract" xlink:label="loc_us-gaap_EarningsPerShareBasicAbstract_3C15586A7AD0B2FDF53F3B7F1FD8EDEF" xlink:type="locator" />
    <link:presentationArc order="11" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_DAC662735372F544509D3B7F1FD80F28" xlink:to="loc_us-gaap_EarningsPerShareBasicAbstract_3C15586A7AD0B2FDF53F3B7F1FD8EDEF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsPerBasicShare" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsPerBasicShare_DB8E38AF4D56B9588D093B7F1FD8260E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareBasicAbstract_3C15586A7AD0B2FDF53F3B7F1FD8EDEF" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsPerBasicShare_DB8E38AF4D56B9588D093B7F1FD8260E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DiscontinuedOperationIncomeLossFromDiscontinuedOperationNetOfTaxPerBasicShare" xlink:label="loc_us-gaap_DiscontinuedOperationIncomeLossFromDiscontinuedOperationNetOfTaxPerBasicShare_2081E2D9505076D43F463B7F1FD86B70" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareBasicAbstract_3C15586A7AD0B2FDF53F3B7F1FD8EDEF" xlink:to="loc_us-gaap_DiscontinuedOperationIncomeLossFromDiscontinuedOperationNetOfTaxPerBasicShare_2081E2D9505076D43F463B7F1FD86B70" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_EarningsPerShareBasic" xlink:label="loc_us-gaap_EarningsPerShareBasic_D0B2B808F4327D272D793B7F1FD8C973" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareBasicAbstract_3C15586A7AD0B2FDF53F3B7F1FD8EDEF" xlink:to="loc_us-gaap_EarningsPerShareBasic_D0B2B808F4327D272D793B7F1FD8C973" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_EarningsPerShareDilutedAbstract" xlink:label="loc_us-gaap_EarningsPerShareDilutedAbstract_C573B5188A616888B9AD3B7F1FD8775D" xlink:type="locator" />
    <link:presentationArc order="12" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_DAC662735372F544509D3B7F1FD80F28" xlink:to="loc_us-gaap_EarningsPerShareDilutedAbstract_C573B5188A616888B9AD3B7F1FD8775D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsPerDilutedShare" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsPerDilutedShare_A98159479A04E8DB00CA3B7F1FD83CBE" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareDilutedAbstract_C573B5188A616888B9AD3B7F1FD8775D" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsPerDilutedShare_A98159479A04E8DB00CA3B7F1FD83CBE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DiscontinuedOperationIncomeLossFromDiscontinuedOperationNetOfTaxPerDilutedShare" xlink:label="loc_us-gaap_DiscontinuedOperationIncomeLossFromDiscontinuedOperationNetOfTaxPerDilutedShare_A7B5CE906B29110038C43B7F1FD864D0" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareDilutedAbstract_C573B5188A616888B9AD3B7F1FD8775D" xlink:to="loc_us-gaap_DiscontinuedOperationIncomeLossFromDiscontinuedOperationNetOfTaxPerDilutedShare_A7B5CE906B29110038C43B7F1FD864D0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_EarningsPerShareDiluted" xlink:label="loc_us-gaap_EarningsPerShareDiluted_9EFC386E61CE6AD3938C3B7F1FD89725" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareDilutedAbstract_C573B5188A616888B9AD3B7F1FD8775D" xlink:to="loc_us-gaap_EarningsPerShareDiluted_9EFC386E61CE6AD3938C3B7F1FD89725" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_E81DC5838DA8701420803B7F1FD81E77" xlink:type="locator" />
    <link:presentationArc order="13" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_DAC662735372F544509D3B7F1FD80F28" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_E81DC5838DA8701420803B7F1FD81E77" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingBasic" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_2E6D6348F6FF51F2B86B3B7F1FD898C3" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_E81DC5838DA8701420803B7F1FD81E77" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_2E6D6348F6FF51F2B86B3B7F1FD898C3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding" xlink:label="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_D52203DF233085CCCC453B7F1FD86FBE" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_E81DC5838DA8701420803B7F1FD81E77" xlink:to="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_D52203DF233085CCCC453B7F1FD86FBE" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/ContractAssetsAndLiabilities" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ContractWithCustomerAssetAndLiabilityAbstract" xlink:label="loc_us-gaap_ContractWithCustomerAssetAndLiabilityAbstract_61B6CED9BDA30379B03E09B584922593" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RevenueFromContractWithCustomerTextBlock" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerTextBlock_FF774C3C307A3FC94F2909B5849233BF" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ContractWithCustomerAssetAndLiabilityAbstract_61B6CED9BDA30379B03E09B584922593" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerTextBlock_FF774C3C307A3FC94F2909B5849233BF" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/ContractAssetsAndLiabilitiesDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ContractWithCustomerAssetAndLiabilityAbstract" xlink:label="loc_us-gaap_ContractWithCustomerAssetAndLiabilityAbstract_B59397CB7B1C2145D0C6F51FABC5B542" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ContractWithCustomerAssetNet" xlink:label="loc_us-gaap_ContractWithCustomerAssetNet_25863D16CC2F35FCD78EF527C3B310A8" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ContractWithCustomerAssetAndLiabilityAbstract_B59397CB7B1C2145D0C6F51FABC5B542" xlink:to="loc_us-gaap_ContractWithCustomerAssetNet_25863D16CC2F35FCD78EF527C3B310A8" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_ContractwithCustomerAssetIncreaseDecrease" xlink:label="loc_endp_ContractwithCustomerAssetIncreaseDecrease_A19E6536AE8FF304599CF529837663BF" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ContractWithCustomerAssetAndLiabilityAbstract_B59397CB7B1C2145D0C6F51FABC5B542" xlink:to="loc_endp_ContractwithCustomerAssetIncreaseDecrease_A19E6536AE8FF304599CF529837663BF" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_ContractwithCustomerAssetIncreaseDecreasePercentage" xlink:label="loc_endp_ContractwithCustomerAssetIncreaseDecreasePercentage_F34169EA0A8B9F42616BF52B94BDED40" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ContractWithCustomerAssetAndLiabilityAbstract_B59397CB7B1C2145D0C6F51FABC5B542" xlink:to="loc_endp_ContractwithCustomerAssetIncreaseDecreasePercentage_F34169EA0A8B9F42616BF52B94BDED40" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ContractWithCustomerLiability" xlink:label="loc_us-gaap_ContractWithCustomerLiability_6145AADAEAD5D16F839FF5280AB1A364" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ContractWithCustomerAssetAndLiabilityAbstract_B59397CB7B1C2145D0C6F51FABC5B542" xlink:to="loc_us-gaap_ContractWithCustomerLiability_6145AADAEAD5D16F839FF5280AB1A364" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_ContractwithCustomerLiabilityIncreaseDecrease" xlink:label="loc_endp_ContractwithCustomerLiabilityIncreaseDecrease_699880971632C235F409F52A5E237C44" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ContractWithCustomerAssetAndLiabilityAbstract_B59397CB7B1C2145D0C6F51FABC5B542" xlink:to="loc_endp_ContractwithCustomerLiabilityIncreaseDecrease_699880971632C235F409F52A5E237C44" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_ContractwithCustomerLiabilityIncreaseDecreasePercentage" xlink:label="loc_endp_ContractwithCustomerLiabilityIncreaseDecreasePercentage_ECD5EA965A61864878F7F52AFDCC6753" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ContractWithCustomerAssetAndLiabilityAbstract_B59397CB7B1C2145D0C6F51FABC5B542" xlink:to="loc_endp_ContractwithCustomerLiabilityIncreaseDecreasePercentage_ECD5EA965A61864878F7F52AFDCC6753" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ContractWithCustomerAssetNetCurrent" xlink:label="loc_us-gaap_ContractWithCustomerAssetNetCurrent_03436777C089775B875BF52E5BED7331" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ContractWithCustomerAssetAndLiabilityAbstract_B59397CB7B1C2145D0C6F51FABC5B542" xlink:to="loc_us-gaap_ContractWithCustomerAssetNetCurrent_03436777C089775B875BF52E5BED7331" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ContractWithCustomerLiabilityCurrent" xlink:label="loc_us-gaap_ContractWithCustomerLiabilityCurrent_F2C818B13ABF79879E57F52F35C9E1E9" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ContractWithCustomerAssetAndLiabilityAbstract_B59397CB7B1C2145D0C6F51FABC5B542" xlink:to="loc_us-gaap_ContractWithCustomerLiabilityCurrent_F2C818B13ABF79879E57F52F35C9E1E9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ContractWithCustomerLiabilityRevenueRecognized" xlink:label="loc_us-gaap_ContractWithCustomerLiabilityRevenueRecognized_4FE8DB21608569397751F54AA6736B94" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ContractWithCustomerAssetAndLiabilityAbstract_B59397CB7B1C2145D0C6F51FABC5B542" xlink:to="loc_us-gaap_ContractWithCustomerLiabilityRevenueRecognized_4FE8DB21608569397751F54AA6736B94" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ContractWithCustomerPerformanceObligationSatisfiedInPreviousPeriod" xlink:label="loc_us-gaap_ContractWithCustomerPerformanceObligationSatisfiedInPreviousPeriod_D1A7AB7FE2A41FD5FBE7F54CC3278993" xlink:type="locator" />
    <link:presentationArc order="10" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ContractWithCustomerAssetAndLiabilityAbstract_B59397CB7B1C2145D0C6F51FABC5B542" xlink:to="loc_us-gaap_ContractWithCustomerPerformanceObligationSatisfiedInPreviousPeriod_D1A7AB7FE2A41FD5FBE7F54CC3278993" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/ContractAssetsAndLiabilitiesTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ContractWithCustomerAssetAndLiabilityAbstract" xlink:label="loc_us-gaap_ContractWithCustomerAssetAndLiabilityAbstract_285762BC8998078BB921F52504145FF3" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ContractWithCustomerAssetAndLiabilityTableTextBlock" xlink:label="loc_us-gaap_ContractWithCustomerAssetAndLiabilityTableTextBlock_3B7AFAE18AA7C3FA08A8F5250418DA34" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ContractWithCustomerAssetAndLiabilityAbstract_285762BC8998078BB921F52504145FF3" xlink:to="loc_us-gaap_ContractWithCustomerAssetAndLiabilityTableTextBlock_3B7AFAE18AA7C3FA08A8F5250418DA34" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/Debt" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DebtDisclosureAbstract" xlink:label="loc_us-gaap_DebtDisclosureAbstract_D121F4E18049B73CAE11F8E0ED9A45C5" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DebtDisclosureTextBlock" xlink:label="loc_us-gaap_DebtDisclosureTextBlock_3565B352EB0CF4CE07E4F8E0ED9A539E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_D121F4E18049B73CAE11F8E0ED9A45C5" xlink:to="loc_us-gaap_DebtDisclosureTextBlock_3565B352EB0CF4CE07E4F8E0ED9A539E" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/DebtComponentsOfTotalIndebtednessDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DebtDisclosureAbstract" xlink:label="loc_us-gaap_DebtDisclosureAbstract_C674E80D91A735A3FCBBF49DB8641D81" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DebtInstrumentTable" xlink:label="loc_us-gaap_DebtInstrumentTable_87F83FFAFF30C7A0D97DF49DB864FDEF" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_C674E80D91A735A3FCBBF49DB8641D81" xlink:to="loc_us-gaap_DebtInstrumentTable_87F83FFAFF30C7A0D97DF49DB864FDEF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DebtInstrumentAxis" xlink:label="loc_us-gaap_DebtInstrumentAxis_1E6A2B576A0C946BEF2DF49DB864CD42" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_87F83FFAFF30C7A0D97DF49DB864FDEF" xlink:to="loc_us-gaap_DebtInstrumentAxis_1E6A2B576A0C946BEF2DF49DB864CD42" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DebtInstrumentNameDomain" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_E4129F6C8DF5FD83219BF49DB8643D99" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentAxis_1E6A2B576A0C946BEF2DF49DB864CD42" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_E4129F6C8DF5FD83219BF49DB8643D99" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_SevenPointTwoFivePercentSeniorNotesDueTwoThousandTwentyTwoMember" xlink:label="loc_endp_SevenPointTwoFivePercentSeniorNotesDueTwoThousandTwentyTwoMember_99F1AB9AAFCBC99C470FF49DB8649729" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_E4129F6C8DF5FD83219BF49DB8643D99" xlink:to="loc_endp_SevenPointTwoFivePercentSeniorNotesDueTwoThousandTwentyTwoMember_99F1AB9AAFCBC99C470FF49DB8649729" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_FivePointSevenFiveSeniorNotesDueOnTwoThousandTwentyTwoMember" xlink:label="loc_endp_FivePointSevenFiveSeniorNotesDueOnTwoThousandTwentyTwoMember_7E29C38655D1F20E42EEF49DB864C76A" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_E4129F6C8DF5FD83219BF49DB8643D99" xlink:to="loc_endp_FivePointSevenFiveSeniorNotesDueOnTwoThousandTwentyTwoMember_7E29C38655D1F20E42EEF49DB864C76A" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_FivePointThreeSevenFiveSeniorNotesDueOnTwoThousandTwentyThreeMember" xlink:label="loc_endp_FivePointThreeSevenFiveSeniorNotesDueOnTwoThousandTwentyThreeMember_598C3ECE67233C1C1D62F49DB864F62C" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_E4129F6C8DF5FD83219BF49DB8643D99" xlink:to="loc_endp_FivePointThreeSevenFiveSeniorNotesDueOnTwoThousandTwentyThreeMember_598C3ECE67233C1C1D62F49DB864F62C" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_SixPointZeroPercentSeniorNotesDueTwoThousandTwentyThreeMember" xlink:label="loc_endp_SixPointZeroPercentSeniorNotesDueTwoThousandTwentyThreeMember_77BFD04C7F94E7512AB2F49DB865DAE5" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_E4129F6C8DF5FD83219BF49DB8643D99" xlink:to="loc_endp_SixPointZeroPercentSeniorNotesDueTwoThousandTwentyThreeMember_77BFD04C7F94E7512AB2F49DB865DAE5" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_FivePointEightSevenFivePercentSeniorSecuredNotesDueTwentyTwentyFourMember" xlink:label="loc_endp_FivePointEightSevenFivePercentSeniorSecuredNotesDueTwentyTwentyFourMember_BBBF6188AC82F431D900F49DB865E95D" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_E4129F6C8DF5FD83219BF49DB8643D99" xlink:to="loc_endp_FivePointEightSevenFivePercentSeniorSecuredNotesDueTwentyTwentyFourMember_BBBF6188AC82F431D900F49DB865E95D" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_A6.00SeniorNotesDue2025Member" xlink:label="loc_endp_A6.00SeniorNotesDue2025Member_3C702EB51F985DE95FC7F49DB865BEA7" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_E4129F6C8DF5FD83219BF49DB8643D99" xlink:to="loc_endp_A6.00SeniorNotesDue2025Member_3C702EB51F985DE95FC7F49DB865BEA7" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_TermLoanBFacilityDueTwoThousandTwentyFourMember" xlink:label="loc_endp_TermLoanBFacilityDueTwoThousandTwentyFourMember_AEE4B34DF8DE8DFD21F9F49DB86522E2" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_E4129F6C8DF5FD83219BF49DB8643D99" xlink:to="loc_endp_TermLoanBFacilityDueTwoThousandTwentyFourMember_AEE4B34DF8DE8DFD21F9F49DB86522E2" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_OtherDebtMember" xlink:label="loc_endp_OtherDebtMember_24E296C81F5FF7E83329F49DB865EFD1" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_E4129F6C8DF5FD83219BF49DB8643D99" xlink:to="loc_endp_OtherDebtMember_24E296C81F5FF7E83329F49DB865EFD1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DebtInstrumentLineItems" xlink:label="loc_us-gaap_DebtInstrumentLineItems_C74500E856F897D2554AF49DB865677D" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_87F83FFAFF30C7A0D97DF49DB864FDEF" xlink:to="loc_us-gaap_DebtInstrumentLineItems_C74500E856F897D2554AF49DB865677D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DebtInstrumentInterestRateEffectivePercentage" xlink:label="loc_us-gaap_DebtInstrumentInterestRateEffectivePercentage_4AA58F960BC3E9357EDCF49DB865006F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_C74500E856F897D2554AF49DB865677D" xlink:to="loc_us-gaap_DebtInstrumentInterestRateEffectivePercentage_4AA58F960BC3E9357EDCF49DB865006F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DebtInstrumentFaceAmount" xlink:label="loc_us-gaap_DebtInstrumentFaceAmount_2098BA1BB737DAAE2BC9F49DB86585BE" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_C74500E856F897D2554AF49DB865677D" xlink:to="loc_us-gaap_DebtInstrumentFaceAmount_2098BA1BB737DAAE2BC9F49DB86585BE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LongTermDebt" xlink:label="loc_us-gaap_LongTermDebt_E72DAA64CABC5F00DA56F49DB865397E" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_C74500E856F897D2554AF49DB865677D" xlink:to="loc_us-gaap_LongTermDebt_E72DAA64CABC5F00DA56F49DB865397E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LongTermDebtCurrent" xlink:label="loc_us-gaap_LongTermDebtCurrent_B7A0F19DBBC4E27A3136F49DB8655A08" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_C74500E856F897D2554AF49DB865677D" xlink:to="loc_us-gaap_LongTermDebtCurrent_B7A0F19DBBC4E27A3136F49DB8655A08" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_DebtInstrumentFaceAmountExcludingCurrentMaturities" xlink:label="loc_endp_DebtInstrumentFaceAmountExcludingCurrentMaturities_A7162C7FEA899BD46330F49DB86552F4" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_C74500E856F897D2554AF49DB865677D" xlink:to="loc_endp_DebtInstrumentFaceAmountExcludingCurrentMaturities_A7162C7FEA899BD46330F49DB86552F4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LongTermDebtNoncurrent" xlink:label="loc_us-gaap_LongTermDebtNoncurrent_B3210D507CE7D4AFF6DEF49DB8659ED5" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_C74500E856F897D2554AF49DB865677D" xlink:to="loc_us-gaap_LongTermDebtNoncurrent_B3210D507CE7D4AFF6DEF49DB8659ED5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DebtInstrumentInterestRateStatedPercentage" xlink:label="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_F6B2716BD1CBCE56B36CF49DB8655287" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_C74500E856F897D2554AF49DB865677D" xlink:to="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_F6B2716BD1CBCE56B36CF49DB8655287" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LongTermDebtFairValue" xlink:label="loc_us-gaap_LongTermDebtFairValue_43F1619DA150275C303EF49DB865D933" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_C74500E856F897D2554AF49DB865677D" xlink:to="loc_us-gaap_LongTermDebtFairValue_43F1619DA150275C303EF49DB865D933" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/DebtCreditFacilityNarrativeDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DebtDisclosureAbstract" xlink:label="loc_us-gaap_DebtDisclosureAbstract_8C022F12896B528FB58FE5B309C71903" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LineOfCreditFacilityTable" xlink:label="loc_us-gaap_LineOfCreditFacilityTable_B810F28E7381535BA895318A5C40AD9C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_8C022F12896B528FB58FE5B309C71903" xlink:to="loc_us-gaap_LineOfCreditFacilityTable_B810F28E7381535BA895318A5C40AD9C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CreditFacilityAxis" xlink:label="loc_us-gaap_CreditFacilityAxis_9BF1A43CCBA4585EB41DB84A70326631" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityTable_B810F28E7381535BA895318A5C40AD9C" xlink:to="loc_us-gaap_CreditFacilityAxis_9BF1A43CCBA4585EB41DB84A70326631" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CreditFacilityDomain" xlink:label="loc_us-gaap_CreditFacilityDomain_1389D3DD816A5E00977166312DE8556B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CreditFacilityAxis_9BF1A43CCBA4585EB41DB84A70326631" xlink:to="loc_us-gaap_CreditFacilityDomain_1389D3DD816A5E00977166312DE8556B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RevolvingCreditFacilityMember" xlink:label="loc_us-gaap_RevolvingCreditFacilityMember_8B406048877D57D7AFAC454459205F97" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CreditFacilityDomain_1389D3DD816A5E00977166312DE8556B" xlink:to="loc_us-gaap_RevolvingCreditFacilityMember_8B406048877D57D7AFAC454459205F97" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LongtermDebtTypeAxis" xlink:label="loc_us-gaap_LongtermDebtTypeAxis_AB9CEDBD28EA51118EDD0FFD8392D8A7" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityTable_B810F28E7381535BA895318A5C40AD9C" xlink:to="loc_us-gaap_LongtermDebtTypeAxis_AB9CEDBD28EA51118EDD0FFD8392D8A7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LongtermDebtTypeDomain" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_3436B72F689D5DCFADD9C21189251588" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_AB9CEDBD28EA51118EDD0FFD8392D8A7" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_3436B72F689D5DCFADD9C21189251588" xlink:type="arc" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_3436B72F689D5DCFADD9C21189251588" xlink:to="loc_us-gaap_RevolvingCreditFacilityMember_8B406048877D57D7AFAC454459205F97" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LineOfCreditFacilityLineItems" xlink:label="loc_us-gaap_LineOfCreditFacilityLineItems_D915533B99465D51A2CF85CF1D597765" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityTable_B810F28E7381535BA895318A5C40AD9C" xlink:to="loc_us-gaap_LineOfCreditFacilityLineItems_D915533B99465D51A2CF85CF1D597765" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LineOfCreditFacilityRemainingBorrowingCapacity" xlink:label="loc_us-gaap_LineOfCreditFacilityRemainingBorrowingCapacity_42200063A7C8515B808727019C3A58E4" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityLineItems_D915533B99465D51A2CF85CF1D597765" xlink:to="loc_us-gaap_LineOfCreditFacilityRemainingBorrowingCapacity_42200063A7C8515B808727019C3A58E4" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/DebtTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DebtDisclosureAbstract" xlink:label="loc_us-gaap_DebtDisclosureAbstract_C48ADD1FDBD5C40BCAF9F49DB86C12E6" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScheduleOfDebtInstrumentsTextBlock" xlink:label="loc_us-gaap_ScheduleOfDebtInstrumentsTextBlock_438299EC0995DD39788BF49DB86CCACD" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_C48ADD1FDBD5C40BCAF9F49DB86C12E6" xlink:to="loc_us-gaap_ScheduleOfDebtInstrumentsTextBlock_438299EC0995DD39788BF49DB86CCACD" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/DiscontinuedOperationsAndDivestitures" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DiscontinuedOperationsAndDisposalGroupsAbstract" xlink:label="loc_us-gaap_DiscontinuedOperationsAndDisposalGroupsAbstract_D1390BFD2AC8CC78996F1D167C4A3FDB" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DisposalGroupsIncludingDiscontinuedOperationsDisclosureTextBlock" xlink:label="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsDisclosureTextBlock_2DD0DD0F8D123C121FA41D167C4A1D32" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DiscontinuedOperationsAndDisposalGroupsAbstract_D1390BFD2AC8CC78996F1D167C4A3FDB" xlink:to="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsDisclosureTextBlock_2DD0DD0F8D123C121FA41D167C4A1D32" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/DiscontinuedOperationsAndDivestituresAstoraDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DiscontinuedOperationsAndDisposalGroupsAbstract" xlink:label="loc_us-gaap_DiscontinuedOperationsAndDisposalGroupsAbstract_0A539F46719C6129265A3B7F1EFE9CFF" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable" xlink:label="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_7F0D5298FBD116FA459A3B7F1EFEC845" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DiscontinuedOperationsAndDisposalGroupsAbstract_0A539F46719C6129265A3B7F1EFE9CFF" xlink:to="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_7F0D5298FBD116FA459A3B7F1EFEC845" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DisposalGroupClassificationAxis" xlink:label="loc_us-gaap_DisposalGroupClassificationAxis_1E6D41EEB64F41C0E96E3B7F1EFE645E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_7F0D5298FBD116FA459A3B7F1EFEC845" xlink:to="loc_us-gaap_DisposalGroupClassificationAxis_1E6D41EEB64F41C0E96E3B7F1EFE645E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DisposalGroupClassificationDomain" xlink:label="loc_us-gaap_DisposalGroupClassificationDomain_B872914F542529BD3C6F3B7F1EFEFC76" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisposalGroupClassificationAxis_1E6D41EEB64F41C0E96E3B7F1EFE645E" xlink:to="loc_us-gaap_DisposalGroupClassificationDomain_B872914F542529BD3C6F3B7F1EFEFC76" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DiscontinuedOperationsDisposedOfBySaleMember" xlink:label="loc_us-gaap_DiscontinuedOperationsDisposedOfBySaleMember_D5B507A3665036D681083B7F1EFE910E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisposalGroupClassificationDomain_B872914F542529BD3C6F3B7F1EFEFC76" xlink:to="loc_us-gaap_DiscontinuedOperationsDisposedOfBySaleMember_D5B507A3665036D681083B7F1EFE910E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis" xlink:label="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_19A87A2DD08DE08B82FD3B7F1EFE165F" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_7F0D5298FBD116FA459A3B7F1EFEC845" xlink:to="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_19A87A2DD08DE08B82FD3B7F1EFE165F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain" xlink:label="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_E4770964862A2D0ACF443B7F1EFEE465" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_19A87A2DD08DE08B82FD3B7F1EFE165F" xlink:to="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_E4770964862A2D0ACF443B7F1EFEE465" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_AstoraMember" xlink:label="loc_endp_AstoraMember_63E74372FAD02CB0C80B3B7F1EFE5F49" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_E4770964862A2D0ACF443B7F1EFEE465" xlink:to="loc_endp_AstoraMember_63E74372FAD02CB0C80B3B7F1EFE5F49" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems" xlink:label="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_E17F6CA1023CAF41B7BE3B7F1EFE2D4C" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_7F0D5298FBD116FA459A3B7F1EFEC845" xlink:to="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_E17F6CA1023CAF41B7BE3B7F1EFE2D4C" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_DisposalGroupIncludingDiscontinuedOperationLitigationRelatedAndOtherContingencies" xlink:label="loc_endp_DisposalGroupIncludingDiscontinuedOperationLitigationRelatedAndOtherContingencies_BF1876E3D7CD22A27CC93B7F1EFE9EA9" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_E17F6CA1023CAF41B7BE3B7F1EFE2D4C" xlink:to="loc_endp_DisposalGroupIncludingDiscontinuedOperationLitigationRelatedAndOtherContingencies_BF1876E3D7CD22A27CC93B7F1EFE9EA9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DiscontinuedOperationIncomeLossFromDiscontinuedOperationBeforeIncomeTax" xlink:label="loc_us-gaap_DiscontinuedOperationIncomeLossFromDiscontinuedOperationBeforeIncomeTax_DF268841961596F1D3BC3B7F1EFEBA33" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_E17F6CA1023CAF41B7BE3B7F1EFE2D4C" xlink:to="loc_us-gaap_DiscontinuedOperationIncomeLossFromDiscontinuedOperationBeforeIncomeTax_DF268841961596F1D3BC3B7F1EFEBA33" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DiscontinuedOperationTaxEffectOfDiscontinuedOperation" xlink:label="loc_us-gaap_DiscontinuedOperationTaxEffectOfDiscontinuedOperation_9490EE49C126C99BA0E53B7F1EFEF10C" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_E17F6CA1023CAF41B7BE3B7F1EFE2D4C" xlink:to="loc_us-gaap_DiscontinuedOperationTaxEffectOfDiscontinuedOperation_9490EE49C126C99BA0E53B7F1EFEF10C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTax" xlink:label="loc_us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTax_F07489AFE969E7783DDC3B7F1EFEB953" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_E17F6CA1023CAF41B7BE3B7F1EFE2D4C" xlink:to="loc_us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTax_F07489AFE969E7783DDC3B7F1EFEB953" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CashProvidedByUsedInInvestingActivitiesDiscontinuedOperations" xlink:label="loc_us-gaap_CashProvidedByUsedInInvestingActivitiesDiscontinuedOperations_4E0DCBFF9696623812B13B7F1EFE2007" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_E17F6CA1023CAF41B7BE3B7F1EFE2D4C" xlink:to="loc_us-gaap_CashProvidedByUsedInInvestingActivitiesDiscontinuedOperations_4E0DCBFF9696623812B13B7F1EFE2007" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationDepreciationAndAmortization" xlink:label="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationDepreciationAndAmortization_2940507B26563696032D3B7F1EFE19B4" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_E17F6CA1023CAF41B7BE3B7F1EFE2D4C" xlink:to="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationDepreciationAndAmortization_2940507B26563696032D3B7F1EFE19B4" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/DiscontinuedOperationsAndDivestituresLithiaNarrativeDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DiscontinuedOperationsAndDisposalGroupsAbstract" xlink:label="loc_us-gaap_DiscontinuedOperationsAndDisposalGroupsAbstract_D26368D271D4F1106BFC1993B60BA7BF" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable" xlink:label="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_58C5500C4B1B5D94DB7F1993B60B935F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DiscontinuedOperationsAndDisposalGroupsAbstract_D26368D271D4F1106BFC1993B60BA7BF" xlink:to="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_58C5500C4B1B5D94DB7F1993B60B935F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.sec.gov/invest/2013/invest-2013-01-31.xsd#invest_InvestmentAxis" xlink:label="loc_invest_InvestmentAxis_B190BC8158E08594A14D1993B60B3EF7" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_58C5500C4B1B5D94DB7F1993B60B935F" xlink:to="loc_invest_InvestmentAxis_B190BC8158E08594A14D1993B60B3EF7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.sec.gov/invest/2013/invest-2013-01-31.xsd#invest_InvestmentDomain" xlink:label="loc_invest_InvestmentDomain_D204A18FEF33F88BAD5F1993B60B2645" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_invest_InvestmentAxis_B190BC8158E08594A14D1993B60B3EF7" xlink:to="loc_invest_InvestmentDomain_D204A18FEF33F88BAD5F1993B60B2645" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_LithaJointVentureInvestmentMember" xlink:label="loc_endp_LithaJointVentureInvestmentMember_86730E1F9579F38FC4971993B60BFBDA" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_invest_InvestmentDomain_D204A18FEF33F88BAD5F1993B60B2645" xlink:to="loc_endp_LithaJointVentureInvestmentMember_86730E1F9579F38FC4971993B60BFBDA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_StatementBusinessSegmentsAxis" xlink:label="loc_us-gaap_StatementBusinessSegmentsAxis_CF51D3A07CD19FDE365B1993B60B995E" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_58C5500C4B1B5D94DB7F1993B60B935F" xlink:to="loc_us-gaap_StatementBusinessSegmentsAxis_CF51D3A07CD19FDE365B1993B60B995E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SegmentDomain" xlink:label="loc_us-gaap_SegmentDomain_6B2063EF4C16326A1B721993B60BAB0C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_CF51D3A07CD19FDE365B1993B60B995E" xlink:to="loc_us-gaap_SegmentDomain_6B2063EF4C16326A1B721993B60BAB0C" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_InternationalPharmaceuticalsMember" xlink:label="loc_endp_InternationalPharmaceuticalsMember_5CD8FA0A6A926823E7C01993B60B1423" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_6B2063EF4C16326A1B721993B60BAB0C" xlink:to="loc_endp_InternationalPharmaceuticalsMember_5CD8FA0A6A926823E7C01993B60B1423" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis" xlink:label="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_EF6C02CC022CD580B7F11993B60C6171" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_58C5500C4B1B5D94DB7F1993B60B935F" xlink:to="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_EF6C02CC022CD580B7F11993B60C6171" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain" xlink:label="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_6AEFA53C491CEE9804E41993B60C8F8E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_EF6C02CC022CD580B7F11993B60C6171" xlink:to="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_6AEFA53C491CEE9804E41993B60C8F8E" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_LithaHealthcareGroupLimitedMember" xlink:label="loc_endp_LithaHealthcareGroupLimitedMember_424B9398B58383CBE48D1993B60C5623" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_6AEFA53C491CEE9804E41993B60C8F8E" xlink:to="loc_endp_LithaHealthcareGroupLimitedMember_424B9398B58383CBE48D1993B60C5623" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DisposalGroupClassificationAxis" xlink:label="loc_us-gaap_DisposalGroupClassificationAxis_2908E3CD31434E3246711993B60C52FB" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_58C5500C4B1B5D94DB7F1993B60B935F" xlink:to="loc_us-gaap_DisposalGroupClassificationAxis_2908E3CD31434E3246711993B60C52FB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DisposalGroupClassificationDomain" xlink:label="loc_us-gaap_DisposalGroupClassificationDomain_A86CA2F6FEAE02E2EECC1993B60C5B76" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisposalGroupClassificationAxis_2908E3CD31434E3246711993B60C52FB" xlink:to="loc_us-gaap_DisposalGroupClassificationDomain_A86CA2F6FEAE02E2EECC1993B60C5B76" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DisposalGroupHeldforsaleNotDiscontinuedOperationsMember" xlink:label="loc_us-gaap_DisposalGroupHeldforsaleNotDiscontinuedOperationsMember_982E9E85F15C26913D4B1993B60C1F97" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisposalGroupClassificationDomain_A86CA2F6FEAE02E2EECC1993B60C5B76" xlink:to="loc_us-gaap_DisposalGroupHeldforsaleNotDiscontinuedOperationsMember_982E9E85F15C26913D4B1993B60C1F97" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems" xlink:label="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_B8D47D88118A2AC25A751993B60DF808" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_58C5500C4B1B5D94DB7F1993B60B935F" xlink:to="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_B8D47D88118A2AC25A751993B60DF808" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ProceedsFromDivestitureOfBusinesses" xlink:label="loc_us-gaap_ProceedsFromDivestitureOfBusinesses_AB5BA51044DA348551F71993B60DB050" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_B8D47D88118A2AC25A751993B60DF808" xlink:to="loc_us-gaap_ProceedsFromDivestitureOfBusinesses_AB5BA51044DA348551F71993B60DB050" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_DisposalGroupIncludingDiscontinuedOperationAdditionalContingentConsiderationReceivable" xlink:label="loc_endp_DisposalGroupIncludingDiscontinuedOperationAdditionalContingentConsiderationReceivable_74F64667B559C95A0B421993B60D6671" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_B8D47D88118A2AC25A751993B60DF808" xlink:to="loc_endp_DisposalGroupIncludingDiscontinuedOperationAdditionalContingentConsiderationReceivable_74F64667B559C95A0B421993B60D6671" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_GainLossOnDispositionOfAssets1" xlink:label="loc_us-gaap_GainLossOnDispositionOfAssets1_B4550135AB6D46A416811993B60D9636" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_B8D47D88118A2AC25A751993B60DF808" xlink:to="loc_us-gaap_GainLossOnDispositionOfAssets1_B4550135AB6D46A416811993B60D9636" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_DisposalGroupIncludingDiscontinuedOperationAdditionalContingentConsiderationPayable" xlink:label="loc_endp_DisposalGroupIncludingDiscontinuedOperationAdditionalContingentConsiderationPayable_C4717E4C9A5F91738F491993B60D7C8F" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_B8D47D88118A2AC25A751993B60DF808" xlink:to="loc_endp_DisposalGroupIncludingDiscontinuedOperationAdditionalContingentConsiderationPayable_C4717E4C9A5F91738F491993B60D7C8F" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/DiscontinuedOperationsAndDivestituresSomarNarrativeDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DiscontinuedOperationsAndDisposalGroupsAbstract" xlink:label="loc_us-gaap_DiscontinuedOperationsAndDisposalGroupsAbstract_F7825811D60C5C0FA577F029ACF08576" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable" xlink:label="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_AFFC00D1C46CD2CBB561F029ACF0CF2D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DiscontinuedOperationsAndDisposalGroupsAbstract_F7825811D60C5C0FA577F029ACF08576" xlink:to="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_AFFC00D1C46CD2CBB561F029ACF0CF2D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis" xlink:label="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_18DE3FF49C385FAE4512F029ACF06A9F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_AFFC00D1C46CD2CBB561F029ACF0CF2D" xlink:to="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_18DE3FF49C385FAE4512F029ACF06A9F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain" xlink:label="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_ECB9BB1C201313528110F029ACF007AF" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_18DE3FF49C385FAE4512F029ACF06A9F" xlink:to="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_ECB9BB1C201313528110F029ACF007AF" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_SomarMember" xlink:label="loc_endp_SomarMember_0287F2AC8161C0805242F029ACF058B5" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_ECB9BB1C201313528110F029ACF007AF" xlink:to="loc_endp_SomarMember_0287F2AC8161C0805242F029ACF058B5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DisposalGroupClassificationAxis" xlink:label="loc_us-gaap_DisposalGroupClassificationAxis_24A1E3AD8777291C38CCF029ACF02FAC" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_AFFC00D1C46CD2CBB561F029ACF0CF2D" xlink:to="loc_us-gaap_DisposalGroupClassificationAxis_24A1E3AD8777291C38CCF029ACF02FAC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DisposalGroupClassificationDomain" xlink:label="loc_us-gaap_DisposalGroupClassificationDomain_174B1B1FEB53A7B1D6B9F029ACF0C686" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisposalGroupClassificationAxis_24A1E3AD8777291C38CCF029ACF02FAC" xlink:to="loc_us-gaap_DisposalGroupClassificationDomain_174B1B1FEB53A7B1D6B9F029ACF0C686" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DisposalGroupHeldforsaleNotDiscontinuedOperationsMember" xlink:label="loc_us-gaap_DisposalGroupHeldforsaleNotDiscontinuedOperationsMember_D1405D6AC7AC6E766557F029ACF13D5A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisposalGroupClassificationDomain_174B1B1FEB53A7B1D6B9F029ACF0C686" xlink:to="loc_us-gaap_DisposalGroupHeldforsaleNotDiscontinuedOperationsMember_D1405D6AC7AC6E766557F029ACF13D5A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems" xlink:label="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_C836524A221922767CBDF029ACF14415" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_AFFC00D1C46CD2CBB561F029ACF0CF2D" xlink:to="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_C836524A221922767CBDF029ACF14415" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationConsideration" xlink:label="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationConsideration_3403D96D4870D84D01D4F029ACF1F8C8" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_C836524A221922767CBDF029ACF14415" xlink:to="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationConsideration_3403D96D4870D84D01D4F029ACF1F8C8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_GainLossOnDispositionOfAssets1" xlink:label="loc_us-gaap_GainLossOnDispositionOfAssets1_15ED1AF62DD128B87FF2F029ACF101E9" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_C836524A221922767CBDF029ACF14415" xlink:to="loc_us-gaap_GainLossOnDispositionOfAssets1_15ED1AF62DD128B87FF2F029ACF101E9" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/DiscontinuedOperationsAndDivestituresTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DiscontinuedOperationsAndDisposalGroupsAbstract" xlink:label="loc_us-gaap_DiscontinuedOperationsAndDisposalGroupsAbstract_E593A1A3F59D14333132EF1765999CEC" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScheduleOfDisposalGroupsIncludingDiscontinuedOperationsIncomeStatementBalanceSheetAndAdditionalDisclosuresTextBlock" xlink:label="loc_us-gaap_ScheduleOfDisposalGroupsIncludingDiscontinuedOperationsIncomeStatementBalanceSheetAndAdditionalDisclosuresTextBlock_351C44C451AECC08216CEF1765996BB2" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DiscontinuedOperationsAndDisposalGroupsAbstract_E593A1A3F59D14333132EF1765999CEC" xlink:to="loc_us-gaap_ScheduleOfDisposalGroupsIncludingDiscontinuedOperationsIncomeStatementBalanceSheetAndAdditionalDisclosuresTextBlock_351C44C451AECC08216CEF1765996BB2" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/DocumentAndEntityInformation" xlink:type="extended">
    <link:loc xlink:href="endp-20180331.xsd#endp_DocumentAndEntityInformationAbstract" xlink:label="loc_endp_DocumentAndEntityInformationAbstract_A2EA6F55CB1A3613E973DF429E399B3D" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.sec.gov/dei/2014/dei-2014-01-31.xsd#dei_DocumentType" xlink:label="loc_dei_DocumentType_BA0B9AE4E087B5E49573DF429E3C88B1" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_DocumentAndEntityInformationAbstract_A2EA6F55CB1A3613E973DF429E399B3D" xlink:to="loc_dei_DocumentType_BA0B9AE4E087B5E49573DF429E3C88B1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.sec.gov/dei/2014/dei-2014-01-31.xsd#dei_AmendmentFlag" xlink:label="loc_dei_AmendmentFlag_23EDB79BDECCB5DCE0F8DF429E3E5CAF" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_DocumentAndEntityInformationAbstract_A2EA6F55CB1A3613E973DF429E399B3D" xlink:to="loc_dei_AmendmentFlag_23EDB79BDECCB5DCE0F8DF429E3E5CAF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.sec.gov/dei/2014/dei-2014-01-31.xsd#dei_DocumentPeriodEndDate" xlink:label="loc_dei_DocumentPeriodEndDate_3118B2F4D2BA3287D918DF429E3EA7F2" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_DocumentAndEntityInformationAbstract_A2EA6F55CB1A3613E973DF429E399B3D" xlink:to="loc_dei_DocumentPeriodEndDate_3118B2F4D2BA3287D918DF429E3EA7F2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.sec.gov/dei/2014/dei-2014-01-31.xsd#dei_DocumentFiscalYearFocus" xlink:label="loc_dei_DocumentFiscalYearFocus_3B1E0C09B0DA6D5103C4DF429E3E857D" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_DocumentAndEntityInformationAbstract_A2EA6F55CB1A3613E973DF429E399B3D" xlink:to="loc_dei_DocumentFiscalYearFocus_3B1E0C09B0DA6D5103C4DF429E3E857D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.sec.gov/dei/2014/dei-2014-01-31.xsd#dei_DocumentFiscalPeriodFocus" xlink:label="loc_dei_DocumentFiscalPeriodFocus_A0A2E35B52D4A383E5F0DF429E3E121D" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_DocumentAndEntityInformationAbstract_A2EA6F55CB1A3613E973DF429E399B3D" xlink:to="loc_dei_DocumentFiscalPeriodFocus_A0A2E35B52D4A383E5F0DF429E3E121D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.sec.gov/dei/2014/dei-2014-01-31.xsd#dei_TradingSymbol" xlink:label="loc_dei_TradingSymbol_42EB3F976DCCDBF5D69FDF429E3EAF40" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_DocumentAndEntityInformationAbstract_A2EA6F55CB1A3613E973DF429E399B3D" xlink:to="loc_dei_TradingSymbol_42EB3F976DCCDBF5D69FDF429E3EAF40" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.sec.gov/dei/2014/dei-2014-01-31.xsd#dei_EntityRegistrantName" xlink:label="loc_dei_EntityRegistrantName_9627B8708090B3BDC12ADF429E3E75FA" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_DocumentAndEntityInformationAbstract_A2EA6F55CB1A3613E973DF429E399B3D" xlink:to="loc_dei_EntityRegistrantName_9627B8708090B3BDC12ADF429E3E75FA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.sec.gov/dei/2014/dei-2014-01-31.xsd#dei_EntityCentralIndexKey" xlink:label="loc_dei_EntityCentralIndexKey_731767B0EFC37E0E1C88DF429E3E154B" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_DocumentAndEntityInformationAbstract_A2EA6F55CB1A3613E973DF429E399B3D" xlink:to="loc_dei_EntityCentralIndexKey_731767B0EFC37E0E1C88DF429E3E154B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.sec.gov/dei/2014/dei-2014-01-31.xsd#dei_CurrentFiscalYearEndDate" xlink:label="loc_dei_CurrentFiscalYearEndDate_A7AE7966569389BFDDB9DF429E3EB7AC" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_DocumentAndEntityInformationAbstract_A2EA6F55CB1A3613E973DF429E399B3D" xlink:to="loc_dei_CurrentFiscalYearEndDate_A7AE7966569389BFDDB9DF429E3EB7AC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.sec.gov/dei/2014/dei-2014-01-31.xsd#dei_EntityFilerCategory" xlink:label="loc_dei_EntityFilerCategory_BD57607CDB451EFB83EADF429E3E2F57" xlink:type="locator" />
    <link:presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_DocumentAndEntityInformationAbstract_A2EA6F55CB1A3613E973DF429E399B3D" xlink:to="loc_dei_EntityFilerCategory_BD57607CDB451EFB83EADF429E3E2F57" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.sec.gov/dei/2014/dei-2014-01-31.xsd#dei_EntityCommonStockSharesOutstanding" xlink:label="loc_dei_EntityCommonStockSharesOutstanding_BAEB219D80AC7FDA52E1DF429E3ECA35" xlink:type="locator" />
    <link:presentationArc order="11" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_DocumentAndEntityInformationAbstract_A2EA6F55CB1A3613E973DF429E399B3D" xlink:to="loc_dei_EntityCommonStockSharesOutstanding_BAEB219D80AC7FDA52E1DF429E3ECA35" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/FairValueMeasurements" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueDisclosuresAbstract" xlink:label="loc_us-gaap_FairValueDisclosuresAbstract_DFF7889B08C95C12A519F635A3040C13" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueDisclosuresTextBlock" xlink:label="loc_us-gaap_FairValueDisclosuresTextBlock_26DBC998F20650E3A17CFB069E4200C2" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_DFF7889B08C95C12A519F635A3040C13" xlink:to="loc_us-gaap_FairValueDisclosuresTextBlock_26DBC998F20650E3A17CFB069E4200C2" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/FairValueMeasurementsFairValueMeasurementsScheduleOfFinancialAssetsMeasuredAtFairValueOnNonrecurringBasisDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueDisclosuresAbstract" xlink:label="loc_us-gaap_FairValueDisclosuresAbstract_CBBCD91E5A55F8EAF1B12877F7AE5BE1" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_0F50444ECCA59A9BB3602877F7AE1B5C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_CBBCD91E5A55F8EAF1B12877F7AE5BE1" xlink:to="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_0F50444ECCA59A9BB3602877F7AE1B5C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueByFairValueHierarchyLevelAxis" xlink:label="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_4A67240CEC4086F7702B2877F7AEAB38" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_0F50444ECCA59A9BB3602877F7AE1B5C" xlink:to="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_4A67240CEC4086F7702B2877F7AEAB38" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_9093519EC6874238FA532877F7AEFA35" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_4A67240CEC4086F7702B2877F7AEAB38" xlink:to="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_9093519EC6874238FA532877F7AEFA35" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueInputsLevel1Member" xlink:label="loc_us-gaap_FairValueInputsLevel1Member_AEF33B51D7E1C63C0FA52877F7AE1C32" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_9093519EC6874238FA532877F7AEFA35" xlink:to="loc_us-gaap_FairValueInputsLevel1Member_AEF33B51D7E1C63C0FA52877F7AE1C32" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueInputsLevel2Member" xlink:label="loc_us-gaap_FairValueInputsLevel2Member_C0715BE2B3143E2382172877F7AED46A" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_9093519EC6874238FA532877F7AEFA35" xlink:to="loc_us-gaap_FairValueInputsLevel2Member_C0715BE2B3143E2382172877F7AED46A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueInputsLevel3Member" xlink:label="loc_us-gaap_FairValueInputsLevel3Member_03F7090E601A060AE9942877F7AE647A" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_9093519EC6874238FA532877F7AEFA35" xlink:to="loc_us-gaap_FairValueInputsLevel3Member_03F7090E601A060AE9942877F7AE647A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueByMeasurementFrequencyAxis" xlink:label="loc_us-gaap_FairValueByMeasurementFrequencyAxis_9DE34FB8A0C28A87290C2877F7AE0C96" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_0F50444ECCA59A9BB3602877F7AE1B5C" xlink:to="loc_us-gaap_FairValueByMeasurementFrequencyAxis_9DE34FB8A0C28A87290C2877F7AE0C96" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueMeasurementFrequencyDomain" xlink:label="loc_us-gaap_FairValueMeasurementFrequencyDomain_7CCDB7EE6C7855C978DF2877F7AE6FDA" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueByMeasurementFrequencyAxis_9DE34FB8A0C28A87290C2877F7AE0C96" xlink:to="loc_us-gaap_FairValueMeasurementFrequencyDomain_7CCDB7EE6C7855C978DF2877F7AE6FDA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueMeasurementsNonrecurringMember" xlink:label="loc_us-gaap_FairValueMeasurementsNonrecurringMember_E5C0160B2CBCD06A717C2877F7AE9BCF" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementFrequencyDomain_7CCDB7EE6C7855C978DF2877F7AE6FDA" xlink:to="loc_us-gaap_FairValueMeasurementsNonrecurringMember_E5C0160B2CBCD06A717C2877F7AE9BCF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueByAssetClassAxis" xlink:label="loc_us-gaap_FairValueByAssetClassAxis_5DDC44218EC422509CAC2877F7AE04EF" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_0F50444ECCA59A9BB3602877F7AE1B5C" xlink:to="loc_us-gaap_FairValueByAssetClassAxis_5DDC44218EC422509CAC2877F7AE04EF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationByAssetClassDomain" xlink:label="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationByAssetClassDomain_F6FE82B16F2725AD97A72877F7AE3624" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueByAssetClassAxis_5DDC44218EC422509CAC2877F7AE04EF" xlink:to="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationByAssetClassDomain_F6FE82B16F2725AD97A72877F7AE3624" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_IntangibleAssetsMember" xlink:label="loc_endp_IntangibleAssetsMember_21EA31CA4CF469A281CE2877F7AE6ECA" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationByAssetClassDomain_F6FE82B16F2725AD97A72877F7AE3624" xlink:to="loc_endp_IntangibleAssetsMember_21EA31CA4CF469A281CE2877F7AE6ECA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_PropertyPlantAndEquipmentMember" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentMember_6F8B4585DEA3E7A674192877F7AE973B" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationByAssetClassDomain_F6FE82B16F2725AD97A72877F7AE3624" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentMember_6F8B4585DEA3E7A674192877F7AE973B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestructuringPlanAxis" xlink:label="loc_us-gaap_RestructuringPlanAxis_9768DC24C97379244B922877F7AE8309" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_0F50444ECCA59A9BB3602877F7AE1B5C" xlink:to="loc_us-gaap_RestructuringPlanAxis_9768DC24C97379244B922877F7AE8309" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestructuringPlanDomain" xlink:label="loc_us-gaap_RestructuringPlanDomain_2E12EDE82E6093F042A32877F7AE39E4" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringPlanAxis_9768DC24C97379244B922877F7AE8309" xlink:to="loc_us-gaap_RestructuringPlanDomain_2E12EDE82E6093F042A32877F7AE39E4" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_USGenericPharmaceuticalsRestructuring2017Member" xlink:label="loc_endp_USGenericPharmaceuticalsRestructuring2017Member_197245871DD3A2A4A4002877F7AE75E4" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringPlanDomain_2E12EDE82E6093F042A32877F7AE39E4" xlink:to="loc_endp_USGenericPharmaceuticalsRestructuring2017Member_197245871DD3A2A4A4002877F7AE75E4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestructuringCostAndReserveAxis" xlink:label="loc_us-gaap_RestructuringCostAndReserveAxis_4DB60A9B3E03563808BC2877F7AEA95F" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_0F50444ECCA59A9BB3602877F7AE1B5C" xlink:to="loc_us-gaap_RestructuringCostAndReserveAxis_4DB60A9B3E03563808BC2877F7AEA95F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_TypeOfRestructuringDomain" xlink:label="loc_us-gaap_TypeOfRestructuringDomain_930682D5590DAC4A4FBC2877F7AE8AFC" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringCostAndReserveAxis_4DB60A9B3E03563808BC2877F7AEA95F" xlink:to="loc_us-gaap_TypeOfRestructuringDomain_930682D5590DAC4A4FBC2877F7AE8AFC" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_AssetImpairmentChargesMember" xlink:label="loc_endp_AssetImpairmentChargesMember_A7C16AE1213F403B36AF2877F7AE0BE8" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfRestructuringDomain_930682D5590DAC4A4FBC2877F7AE8AFC" xlink:to="loc_endp_AssetImpairmentChargesMember_A7C16AE1213F403B36AF2877F7AE0BE8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_4FA5B04161E6FBE185E92877F7AFDCA1" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_0F50444ECCA59A9BB3602877F7AE1B5C" xlink:to="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_4FA5B04161E6FBE185E92877F7AFDCA1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestructuringCharges" xlink:label="loc_us-gaap_RestructuringCharges_1EC29EC0CD6F03C9CC7F2877F7AF1DA7" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_4FA5B04161E6FBE185E92877F7AFDCA1" xlink:to="loc_us-gaap_RestructuringCharges_1EC29EC0CD6F03C9CC7F2877F7AF1DA7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AssetsFairValueDisclosureAbstract" xlink:label="loc_us-gaap_AssetsFairValueDisclosureAbstract_14AECCC558FCBCDF3E6E2877F7AFABE9" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_4FA5B04161E6FBE185E92877F7AFDCA1" xlink:to="loc_us-gaap_AssetsFairValueDisclosureAbstract_14AECCC558FCBCDF3E6E2877F7AFABE9" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_IntangibleAssetsExcludingGoodwillFairValueDisclosure" xlink:label="loc_endp_IntangibleAssetsExcludingGoodwillFairValueDisclosure_FC4DE7E0068EE15A7DDE28B4F14874E6" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsFairValueDisclosureAbstract_14AECCC558FCBCDF3E6E2877F7AFABE9" xlink:to="loc_endp_IntangibleAssetsExcludingGoodwillFairValueDisclosure_FC4DE7E0068EE15A7DDE28B4F14874E6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_PropertyPlantAndEquipmentFairValueDisclosure" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentFairValueDisclosure_5D05FD5292E1F10D6C982877F7AF10E3" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsFairValueDisclosureAbstract_14AECCC558FCBCDF3E6E2877F7AFABE9" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentFairValueDisclosure_5D05FD5292E1F10D6C982877F7AF10E3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AssetsFairValueDisclosure" xlink:label="loc_us-gaap_AssetsFairValueDisclosure_F2E52D772F539CBEB6E92877F7AF9EF0" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsFairValueDisclosureAbstract_14AECCC558FCBCDF3E6E2877F7AFABE9" xlink:to="loc_us-gaap_AssetsFairValueDisclosure_F2E52D772F539CBEB6E92877F7AF9EF0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AssetImpairmentCharges" xlink:label="loc_us-gaap_AssetImpairmentCharges_B6E6518E1A76BB6E0E722877F7AF3871" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsFairValueDisclosureAbstract_14AECCC558FCBCDF3E6E2877F7AFABE9" xlink:to="loc_us-gaap_AssetImpairmentCharges_B6E6518E1A76BB6E0E722877F7AF3871" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/FairValueMeasurementsFinancialAssetsAndLiabilitiesMeasuredAtFairValueOnRecurringBasisDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueDisclosuresAbstract" xlink:label="loc_us-gaap_FairValueDisclosuresAbstract_5846B282FFD65940BC798C4BEF8144D1" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationTable" xlink:label="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationTable_8E91F51BF99F556DBCC641B98D08C877" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_5846B282FFD65940BC798C4BEF8144D1" xlink:to="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationTable_8E91F51BF99F556DBCC641B98D08C877" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueByFairValueHierarchyLevelAxis" xlink:label="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_96603DB2E62E51A091E692AF0879030B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationTable_8E91F51BF99F556DBCC641B98D08C877" xlink:to="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_96603DB2E62E51A091E692AF0879030B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_86542A2C1A1E5E61863F98619BE04E25" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_96603DB2E62E51A091E692AF0879030B" xlink:to="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_86542A2C1A1E5E61863F98619BE04E25" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueInputsLevel1Member" xlink:label="loc_us-gaap_FairValueInputsLevel1Member_C3E77CB901095905B35737190A0AF6EA" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_86542A2C1A1E5E61863F98619BE04E25" xlink:to="loc_us-gaap_FairValueInputsLevel1Member_C3E77CB901095905B35737190A0AF6EA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueInputsLevel2Member" xlink:label="loc_us-gaap_FairValueInputsLevel2Member_215BC79E29E75E0FBA36374FFC80317C" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_86542A2C1A1E5E61863F98619BE04E25" xlink:to="loc_us-gaap_FairValueInputsLevel2Member_215BC79E29E75E0FBA36374FFC80317C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueInputsLevel3Member" xlink:label="loc_us-gaap_FairValueInputsLevel3Member_0A3508E320E3507087BD29037EB07F1E" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_86542A2C1A1E5E61863F98619BE04E25" xlink:to="loc_us-gaap_FairValueInputsLevel3Member_0A3508E320E3507087BD29037EB07F1E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_MajorTypesOfDebtAndEquitySecuritiesAxis" xlink:label="loc_us-gaap_MajorTypesOfDebtAndEquitySecuritiesAxis_170F53FB17D951C0B07560107412CC18" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationTable_8E91F51BF99F556DBCC641B98D08C877" xlink:to="loc_us-gaap_MajorTypesOfDebtAndEquitySecuritiesAxis_170F53FB17D951C0B07560107412CC18" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_MajorTypesOfDebtAndEquitySecuritiesDomain" xlink:label="loc_us-gaap_MajorTypesOfDebtAndEquitySecuritiesDomain_5582B2652A4B5EC481ED305A86002753" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MajorTypesOfDebtAndEquitySecuritiesAxis_170F53FB17D951C0B07560107412CC18" xlink:to="loc_us-gaap_MajorTypesOfDebtAndEquitySecuritiesDomain_5582B2652A4B5EC481ED305A86002753" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_MoneyMarketFundsMember" xlink:label="loc_us-gaap_MoneyMarketFundsMember_899BBCAB867854A5BB793A3E07B6DA45" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MajorTypesOfDebtAndEquitySecuritiesDomain_5582B2652A4B5EC481ED305A86002753" xlink:to="loc_us-gaap_MoneyMarketFundsMember_899BBCAB867854A5BB793A3E07B6DA45" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BankTimeDepositsMember" xlink:label="loc_us-gaap_BankTimeDepositsMember_450AA5DC71355B53AB6803C2DA35AA29" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MajorTypesOfDebtAndEquitySecuritiesDomain_5582B2652A4B5EC481ED305A86002753" xlink:to="loc_us-gaap_BankTimeDepositsMember_450AA5DC71355B53AB6803C2DA35AA29" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_EquitySecuritiesMember" xlink:label="loc_us-gaap_EquitySecuritiesMember_62DB5524F13A562D8841A968C62B9901" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MajorTypesOfDebtAndEquitySecuritiesDomain_5582B2652A4B5EC481ED305A86002753" xlink:to="loc_us-gaap_EquitySecuritiesMember_62DB5524F13A562D8841A968C62B9901" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ContingentConsiderationByTypeAxis" xlink:label="loc_us-gaap_ContingentConsiderationByTypeAxis_721D47E371EE5E4B9A0B0AA7FBC57553" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationTable_8E91F51BF99F556DBCC641B98D08C877" xlink:to="loc_us-gaap_ContingentConsiderationByTypeAxis_721D47E371EE5E4B9A0B0AA7FBC57553" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ContingentConsiderationTypeDomain" xlink:label="loc_us-gaap_ContingentConsiderationTypeDomain_AB8502ADA9DC5875B44EA6E5C43D365C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ContingentConsiderationByTypeAxis_721D47E371EE5E4B9A0B0AA7FBC57553" xlink:to="loc_us-gaap_ContingentConsiderationTypeDomain_AB8502ADA9DC5875B44EA6E5C43D365C" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_AcquisitionRelatedContingentConsiderationShortTermMember" xlink:label="loc_endp_AcquisitionRelatedContingentConsiderationShortTermMember_3DC67EDCCA965C8C8824E2425FD6CD29" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ContingentConsiderationTypeDomain_AB8502ADA9DC5875B44EA6E5C43D365C" xlink:to="loc_endp_AcquisitionRelatedContingentConsiderationShortTermMember_3DC67EDCCA965C8C8824E2425FD6CD29" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_AcquisitionRelatedContingentConsiderationLongTermMember" xlink:label="loc_endp_AcquisitionRelatedContingentConsiderationLongTermMember_414BD2EB96B25AC6B53EA59B492DCFFE" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ContingentConsiderationTypeDomain_AB8502ADA9DC5875B44EA6E5C43D365C" xlink:to="loc_endp_AcquisitionRelatedContingentConsiderationLongTermMember_414BD2EB96B25AC6B53EA59B492DCFFE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationLineItems" xlink:label="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationLineItems_5007BC1A2CA25D839E63840FF439E07F" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationTable_8E91F51BF99F556DBCC641B98D08C877" xlink:to="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationLineItems_5007BC1A2CA25D839E63840FF439E07F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AssetsAbstract" xlink:label="loc_us-gaap_AssetsAbstract_E5AEF20F03E35645B86B219CF9AEACE0" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationLineItems_5007BC1A2CA25D839E63840FF439E07F" xlink:to="loc_us-gaap_AssetsAbstract_E5AEF20F03E35645B86B219CF9AEACE0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AssetsFairValueDisclosureRecurring" xlink:label="loc_us-gaap_AssetsFairValueDisclosureRecurring_36E965447F2F5332B2DE8FF65DB031AF" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_E5AEF20F03E35645B86B219CF9AEACE0" xlink:to="loc_us-gaap_AssetsFairValueDisclosureRecurring_36E965447F2F5332B2DE8FF65DB031AF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LiabilitiesAbstract" xlink:label="loc_us-gaap_LiabilitiesAbstract_EBE4830D40925DBCA7C0BBF1C54B6376" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationLineItems_5007BC1A2CA25D839E63840FF439E07F" xlink:to="loc_us-gaap_LiabilitiesAbstract_EBE4830D40925DBCA7C0BBF1C54B6376" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LiabilitiesFairValueDisclosureRecurring" xlink:label="loc_us-gaap_LiabilitiesFairValueDisclosureRecurring_7633C0D386165E24A1B5E8CB077E887D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAbstract_EBE4830D40925DBCA7C0BBF1C54B6376" xlink:to="loc_us-gaap_LiabilitiesFairValueDisclosureRecurring_7633C0D386165E24A1B5E8CB077E887D" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/FairValueMeasurementsFinancialLiabilitiesMeasuredAtFairValueOnRecurringBasisUsingSignificantUnobservableInputsDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueDisclosuresAbstract" xlink:label="loc_us-gaap_FairValueDisclosuresAbstract_C8A44D786F448C7158F7F8E0EDEB3900" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationTable" xlink:label="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationTable_CFAD232D6B9C7560E69CF8E0EDEB6AB0" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_C8A44D786F448C7158F7F8E0EDEB3900" xlink:to="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationTable_CFAD232D6B9C7560E69CF8E0EDEB6AB0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ContingentConsiderationByTypeAxis" xlink:label="loc_us-gaap_ContingentConsiderationByTypeAxis_B46124E05B55DBFC1BCFF8E0EDEBA1AB" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationTable_CFAD232D6B9C7560E69CF8E0EDEB6AB0" xlink:to="loc_us-gaap_ContingentConsiderationByTypeAxis_B46124E05B55DBFC1BCFF8E0EDEBA1AB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ContingentConsiderationTypeDomain" xlink:label="loc_us-gaap_ContingentConsiderationTypeDomain_9A9F2F6AD74219EA5EB1F8E0EDEB3466" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ContingentConsiderationByTypeAxis_B46124E05B55DBFC1BCFF8E0EDEBA1AB" xlink:to="loc_us-gaap_ContingentConsiderationTypeDomain_9A9F2F6AD74219EA5EB1F8E0EDEB3466" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_AcquisitionRelatedContingentConsiderationMember" xlink:label="loc_endp_AcquisitionRelatedContingentConsiderationMember_A6D09F10D7B888A650B1F8E0EDEB0BDB" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ContingentConsiderationTypeDomain_9A9F2F6AD74219EA5EB1F8E0EDEB3466" xlink:to="loc_endp_AcquisitionRelatedContingentConsiderationMember_A6D09F10D7B888A650B1F8E0EDEB0BDB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessAcquisitionAxis" xlink:label="loc_us-gaap_BusinessAcquisitionAxis_BFAAC1C7F552A41CEC1AF8E0EDEBF9F9" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationTable_CFAD232D6B9C7560E69CF8E0EDEB6AB0" xlink:to="loc_us-gaap_BusinessAcquisitionAxis_BFAAC1C7F552A41CEC1AF8E0EDEBF9F9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_A1C313BCF6DD32406439F8E0EDEBA132" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_BFAAC1C7F552A41CEC1AF8E0EDEBF9F9" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_A1C313BCF6DD32406439F8E0EDEBA132" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_AuxiliumPharmaceuticalsInc.Member" xlink:label="loc_endp_AuxiliumPharmaceuticalsInc.Member_6DD21C7B731879248F28F8E0EDEBA5A4" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_A1C313BCF6DD32406439F8E0EDEBA132" xlink:to="loc_endp_AuxiliumPharmaceuticalsInc.Member_6DD21C7B731879248F28F8E0EDEBA5A4" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_LehighValleyTechnologiesInc.Member" xlink:label="loc_endp_LehighValleyTechnologiesInc.Member_CDE8724F92B9AEA5C43DF8E0EDEB316D" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_A1C313BCF6DD32406439F8E0EDEBA132" xlink:to="loc_endp_LehighValleyTechnologiesInc.Member_CDE8724F92B9AEA5C43DF8E0EDEB316D" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_VoltarenGelMember" xlink:label="loc_endp_VoltarenGelMember_29ACD191DD59142BA153F8E0EDEB7E25" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_A1C313BCF6DD32406439F8E0EDEBA132" xlink:to="loc_endp_VoltarenGelMember_29ACD191DD59142BA153F8E0EDEB7E25" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_OtherAcquisitionsMember" xlink:label="loc_endp_OtherAcquisitionsMember_385D4B18D35F1F2DF5FCF8E0EDEB490B" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_A1C313BCF6DD32406439F8E0EDEBA132" xlink:to="loc_endp_OtherAcquisitionsMember_385D4B18D35F1F2DF5FCF8E0EDEB490B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationLineItems" xlink:label="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationLineItems_5FDDF86E69666F697AEAF8E0EDEB8BC8" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationTable_CFAD232D6B9C7560E69CF8E0EDEB6AB0" xlink:to="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationLineItems_5FDDF86E69666F697AEAF8E0EDEB8BC8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward" xlink:label="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_18FC8D5F49071995F17CF8E0EDEBA318" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationLineItems_5FDDF86E69666F697AEAF8E0EDEB8BC8" xlink:to="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_18FC8D5F49071995F17CF8E0EDEBA318" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue" xlink:label="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue_CB601F1BD42C65D6D93FF8E0EDEBED17" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_18FC8D5F49071995F17CF8E0EDEBA318" xlink:to="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue_CB601F1BD42C65D6D93FF8E0EDEBED17" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilitySettlements" xlink:label="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilitySettlements_C00B2AB267B226C3549CF8E0EDEBA038" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_18FC8D5F49071995F17CF8E0EDEBA318" xlink:to="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilitySettlements_C00B2AB267B226C3549CF8E0EDEBA038" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityGainLossIncludedInEarnings" xlink:label="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityGainLossIncludedInEarnings_E1706A08880E8D32704CF8E0EDEBDED0" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_18FC8D5F49071995F17CF8E0EDEBA318" xlink:to="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityGainLossIncludedInEarnings_E1706A08880E8D32704CF8E0EDEBDED0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisGainLossIncludedInOtherComprehensiveIncomeLoss" xlink:label="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisGainLossIncludedInOtherComprehensiveIncomeLoss_589C5E1CEFA7A051497CF8E0EDECC3D2" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_18FC8D5F49071995F17CF8E0EDEBA318" xlink:to="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisGainLossIncludedInOtherComprehensiveIncomeLoss_589C5E1CEFA7A051497CF8E0EDECC3D2" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_FairValueMeasurementwithUnobservableInputsReconciliationRecurringBasisLiabilityAdjustmentsAndAccretion" xlink:label="loc_endp_FairValueMeasurementwithUnobservableInputsReconciliationRecurringBasisLiabilityAdjustmentsAndAccretion_065F9872FF6B84215FFCF8E0EDECCFFE" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_18FC8D5F49071995F17CF8E0EDEBA318" xlink:to="loc_endp_FairValueMeasurementwithUnobservableInputsReconciliationRecurringBasisLiabilityAdjustmentsAndAccretion_065F9872FF6B84215FFCF8E0EDECCFFE" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilitySettlementsAndEffectOfCurrencyTranslation" xlink:label="loc_endp_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilitySettlementsAndEffectOfCurrencyTranslation_36F25890C820AC1940F1F8E0EDECF80A" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_18FC8D5F49071995F17CF8E0EDEBA318" xlink:to="loc_endp_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilitySettlementsAndEffectOfCurrencyTranslation_36F25890C820AC1940F1F8E0EDECF80A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue" xlink:label="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue_84B4B171ABD8CDDA76ACF8E0EDEC036A" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_18FC8D5F49071995F17CF8E0EDEBA318" xlink:to="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue_84B4B171ABD8CDDA76ACF8E0EDEC036A" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/FairValueMeasurementsNarrativeDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueDisclosuresAbstract" xlink:label="loc_us-gaap_FairValueDisclosuresAbstract_22670B68B7A6AE31A0CAF48E6A2F835D" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationTable" xlink:label="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationTable_ACA9D186763304837753F48E6A2F5F74" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_22670B68B7A6AE31A0CAF48E6A2F835D" xlink:to="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationTable_ACA9D186763304837753F48E6A2F5F74" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_MajorTypesOfDebtAndEquitySecuritiesAxis" xlink:label="loc_us-gaap_MajorTypesOfDebtAndEquitySecuritiesAxis_22B9D377310A997F4B25F48E6A2FF83C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationTable_ACA9D186763304837753F48E6A2F5F74" xlink:to="loc_us-gaap_MajorTypesOfDebtAndEquitySecuritiesAxis_22B9D377310A997F4B25F48E6A2FF83C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_MajorTypesOfDebtAndEquitySecuritiesDomain" xlink:label="loc_us-gaap_MajorTypesOfDebtAndEquitySecuritiesDomain_66DE7134E89C927D57F9F48E6A2F7031" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MajorTypesOfDebtAndEquitySecuritiesAxis_22B9D377310A997F4B25F48E6A2FF83C" xlink:to="loc_us-gaap_MajorTypesOfDebtAndEquitySecuritiesDomain_66DE7134E89C927D57F9F48E6A2F7031" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_MoneyMarketFundsMember" xlink:label="loc_us-gaap_MoneyMarketFundsMember_A5FC771805F6A2C59EBBF48E6A2F1D48" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MajorTypesOfDebtAndEquitySecuritiesDomain_66DE7134E89C927D57F9F48E6A2F7031" xlink:to="loc_us-gaap_MoneyMarketFundsMember_A5FC771805F6A2C59EBBF48E6A2F1D48" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LitigationCaseAxis" xlink:label="loc_us-gaap_LitigationCaseAxis_60FD01D9A3E72BE7E027F48E6A2FD4D3" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationTable_ACA9D186763304837753F48E6A2F5F74" xlink:to="loc_us-gaap_LitigationCaseAxis_60FD01D9A3E72BE7E027F48E6A2FD4D3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LitigationCaseTypeDomain" xlink:label="loc_us-gaap_LitigationCaseTypeDomain_42E9382105E37035C953F48E6A2F0C8C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LitigationCaseAxis_60FD01D9A3E72BE7E027F48E6A2FD4D3" xlink:to="loc_us-gaap_LitigationCaseTypeDomain_42E9382105E37035C953F48E6A2F0C8C" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_VaginalMeshCasesMember" xlink:label="loc_endp_VaginalMeshCasesMember_5162B7492BB5D48AC5DFF48E6A2F553C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LitigationCaseTypeDomain_42E9382105E37035C953F48E6A2F0C8C" xlink:to="loc_endp_VaginalMeshCasesMember_5162B7492BB5D48AC5DFF48E6A2F553C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_InvestmentTypeAxis" xlink:label="loc_us-gaap_InvestmentTypeAxis_925855C74D2F6B527C43F48E6A2F47D0" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationTable_ACA9D186763304837753F48E6A2F5F74" xlink:to="loc_us-gaap_InvestmentTypeAxis_925855C74D2F6B527C43F48E6A2F47D0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_InvestmentTypeCategorizationMember" xlink:label="loc_us-gaap_InvestmentTypeCategorizationMember_741ECD3C6DF6166E3485F48E6A2F7A7F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InvestmentTypeAxis_925855C74D2F6B527C43F48E6A2F47D0" xlink:to="loc_us-gaap_InvestmentTypeCategorizationMember_741ECD3C6DF6166E3485F48E6A2F7A7F" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_RestrictedCashAndCashEquivalentsMember" xlink:label="loc_endp_RestrictedCashAndCashEquivalentsMember_856D2114687AD5791DE5F48E6A2F1AA2" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InvestmentTypeCategorizationMember_741ECD3C6DF6166E3485F48E6A2F7A7F" xlink:to="loc_endp_RestrictedCashAndCashEquivalentsMember_856D2114687AD5791DE5F48E6A2F1AA2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RangeAxis" xlink:label="loc_us-gaap_RangeAxis_80E3D0F8CD63B927E1A7F48E6A2F9E74" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationTable_ACA9D186763304837753F48E6A2F5F74" xlink:to="loc_us-gaap_RangeAxis_80E3D0F8CD63B927E1A7F48E6A2F9E74" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RangeMember" xlink:label="loc_us-gaap_RangeMember_FC2AB98585E22FCAE718F48E6A2F37F1" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RangeAxis_80E3D0F8CD63B927E1A7F48E6A2F9E74" xlink:to="loc_us-gaap_RangeMember_FC2AB98585E22FCAE718F48E6A2F37F1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_MinimumMember" xlink:label="loc_us-gaap_MinimumMember_0CE682880E9D90B84E8CF48E6A2F1043" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RangeMember_FC2AB98585E22FCAE718F48E6A2F37F1" xlink:to="loc_us-gaap_MinimumMember_0CE682880E9D90B84E8CF48E6A2F1043" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_MaximumMember" xlink:label="loc_us-gaap_MaximumMember_0B663B4D3186013796E3F48E6A2FF426" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RangeMember_FC2AB98585E22FCAE718F48E6A2F37F1" xlink:to="loc_us-gaap_MaximumMember_0B663B4D3186013796E3F48E6A2FF426" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_WeightedAverageMember" xlink:label="loc_us-gaap_WeightedAverageMember_A481CF6CAAC0139C404EF48E6A2FFB63" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RangeMember_FC2AB98585E22FCAE718F48E6A2F37F1" xlink:to="loc_us-gaap_WeightedAverageMember_A481CF6CAAC0139C404EF48E6A2FFB63" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationLineItems" xlink:label="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationLineItems_9F6DB02CA39AA9FC720DF48E6A2F081E" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationTable_ACA9D186763304837753F48E6A2F5F74" xlink:to="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationLineItems_9F6DB02CA39AA9FC720DF48E6A2F081E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestrictedCashAndCashEquivalents" xlink:label="loc_us-gaap_RestrictedCashAndCashEquivalents_C443C68BD61CAAE80F80F48E6A2F43D6" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationLineItems_9F6DB02CA39AA9FC720DF48E6A2F081E" xlink:to="loc_us-gaap_RestrictedCashAndCashEquivalents_C443C68BD61CAAE80F80F48E6A2F43D6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestrictedCashCurrent" xlink:label="loc_us-gaap_RestrictedCashCurrent_5B54223AC9AB0D8E932EF48E6A2FCBB7" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationLineItems_9F6DB02CA39AA9FC720DF48E6A2F081E" xlink:to="loc_us-gaap_RestrictedCashCurrent_5B54223AC9AB0D8E932EF48E6A2FCBB7" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_SettlementFunds" xlink:label="loc_endp_SettlementFunds_302ABE73D7C04FCE06E7F48E6A2F0E90" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationLineItems_9F6DB02CA39AA9FC720DF48E6A2F081E" xlink:to="loc_endp_SettlementFunds_302ABE73D7C04FCE06E7F48E6A2F0E90" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueInputsDiscountRate" xlink:label="loc_us-gaap_FairValueInputsDiscountRate_31CF1A18AE3C28EBC515F48E6A2F20CA" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationLineItems_9F6DB02CA39AA9FC720DF48E6A2F081E" xlink:to="loc_us-gaap_FairValueInputsDiscountRate_31CF1A18AE3C28EBC515F48E6A2F20CA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_GoodwillImpairmentLoss" xlink:label="loc_us-gaap_GoodwillImpairmentLoss_2682C012B0266FAB6B24F48E6A2FA313" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationLineItems_9F6DB02CA39AA9FC720DF48E6A2F081E" xlink:to="loc_us-gaap_GoodwillImpairmentLoss_2682C012B0266FAB6B24F48E6A2FA313" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/FairValueMeasurementsTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueDisclosuresAbstract" xlink:label="loc_us-gaap_FairValueDisclosuresAbstract_83369952E3D85EA698A35756167B7E04" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock_2D2F2A5E08B35446B7702C652EEC2116" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_83369952E3D85EA698A35756167B7E04" xlink:to="loc_us-gaap_ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock_2D2F2A5E08B35446B7702C652EEC2116" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationTextBlock" xlink:label="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationTextBlock_6A0DB00ED0485628AAAD5B02214A3561" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_83369952E3D85EA698A35756167B7E04" xlink:to="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationTextBlock_6A0DB00ED0485628AAAD5B02214A3561" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueAssetsMeasuredOnNonrecurringBasisTextBlock" xlink:label="loc_us-gaap_FairValueAssetsMeasuredOnNonrecurringBasisTextBlock_6718E4CD52C05FA38A0806F11C76902E" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_83369952E3D85EA698A35756167B7E04" xlink:to="loc_us-gaap_FairValueAssetsMeasuredOnNonrecurringBasisTextBlock_6718E4CD52C05FA38A0806F11C76902E" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/GoodwillAndOtherIntangibles" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract" xlink:label="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_8D75DEB8CBCE5A03A6E4D60CAAE4B697" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_GoodwillAndIntangibleAssetsDisclosureTextBlock" xlink:label="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureTextBlock_8D839EF762D050E9AE6A265A5F4610F6" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_8D75DEB8CBCE5A03A6E4D60CAAE4B697" xlink:to="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureTextBlock_8D839EF762D050E9AE6A265A5F4610F6" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/GoodwillAndOtherIntangiblesAccumulatedImpairmentDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract" xlink:label="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_E9D0D2C44F06C4AD4BDCF8E0EDCB4AE5" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScheduleOfGoodwillTable" xlink:label="loc_us-gaap_ScheduleOfGoodwillTable_A7605E62CE50E95244B6F8E0EDCB8B20" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_E9D0D2C44F06C4AD4BDCF8E0EDCB4AE5" xlink:to="loc_us-gaap_ScheduleOfGoodwillTable_A7605E62CE50E95244B6F8E0EDCB8B20" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_StatementBusinessSegmentsAxis" xlink:label="loc_us-gaap_StatementBusinessSegmentsAxis_079D3C670A308FC42C37F8E0EDCBAA36" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfGoodwillTable_A7605E62CE50E95244B6F8E0EDCB8B20" xlink:to="loc_us-gaap_StatementBusinessSegmentsAxis_079D3C670A308FC42C37F8E0EDCBAA36" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SegmentDomain" xlink:label="loc_us-gaap_SegmentDomain_358AEE8022B49E09B26EF8E0EDCBA2B6" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_079D3C670A308FC42C37F8E0EDCBAA36" xlink:to="loc_us-gaap_SegmentDomain_358AEE8022B49E09B26EF8E0EDCBA2B6" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_BrandedSpecialtyandEstablishedPharmaceuticalsMember" xlink:label="loc_endp_BrandedSpecialtyandEstablishedPharmaceuticalsMember_9C332C0FFD6AAC75198DF8E0EDCC9CE1" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_358AEE8022B49E09B26EF8E0EDCBA2B6" xlink:to="loc_endp_BrandedSpecialtyandEstablishedPharmaceuticalsMember_9C332C0FFD6AAC75198DF8E0EDCC9CE1" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_BrandedSterileInjectablesMember" xlink:label="loc_endp_BrandedSterileInjectablesMember_26A1FACA56BCF7AFF78DF8E0EDCC5353" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_358AEE8022B49E09B26EF8E0EDCBA2B6" xlink:to="loc_endp_BrandedSterileInjectablesMember_26A1FACA56BCF7AFF78DF8E0EDCC5353" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_GenericPharmaceuticalsMember" xlink:label="loc_endp_GenericPharmaceuticalsMember_CCC42EAC02F915C91021F8E0EDCCC982" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_358AEE8022B49E09B26EF8E0EDCBA2B6" xlink:to="loc_endp_GenericPharmaceuticalsMember_CCC42EAC02F915C91021F8E0EDCCC982" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_InternationalPharmaceuticalsMember" xlink:label="loc_endp_InternationalPharmaceuticalsMember_BCE19A8207E860D9F12DF8E0EDCCFBEE" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_358AEE8022B49E09B26EF8E0EDCBA2B6" xlink:to="loc_endp_InternationalPharmaceuticalsMember_BCE19A8207E860D9F12DF8E0EDCCFBEE" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_FormerU.S.GenericPharmaceuticalsMember" xlink:label="loc_endp_FormerU.S.GenericPharmaceuticalsMember_3B32899D5E452F4AD34FF8E0EDCC433B" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_358AEE8022B49E09B26EF8E0EDCBA2B6" xlink:to="loc_endp_FormerU.S.GenericPharmaceuticalsMember_3B32899D5E452F4AD34FF8E0EDCC433B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_GoodwillLineItems" xlink:label="loc_us-gaap_GoodwillLineItems_3EB1C059C8277B3197C5F8E0EDCC236C" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfGoodwillTable_A7605E62CE50E95244B6F8E0EDCB8B20" xlink:to="loc_us-gaap_GoodwillLineItems_3EB1C059C8277B3197C5F8E0EDCC236C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_GoodwillImpairedAccumulatedImpairmentLoss" xlink:label="loc_us-gaap_GoodwillImpairedAccumulatedImpairmentLoss_1B50762C2D2DD394EA61F8E0EDCCAD61" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillLineItems_3EB1C059C8277B3197C5F8E0EDCC236C" xlink:to="loc_us-gaap_GoodwillImpairedAccumulatedImpairmentLoss_1B50762C2D2DD394EA61F8E0EDCCAD61" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/GoodwillAndOtherIntangiblesImpairmentsNarrativeDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract" xlink:label="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_4B336D7CFBF998194B831D167A453111" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScheduleOfGoodwillTable" xlink:label="loc_us-gaap_ScheduleOfGoodwillTable_B3C5C5D996132C4607E71D167A450F78" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_4B336D7CFBF998194B831D167A453111" xlink:to="loc_us-gaap_ScheduleOfGoodwillTable_B3C5C5D996132C4607E71D167A450F78" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_369E87948E40511C67811D167A45FE3D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfGoodwillTable_B3C5C5D996132C4607E71D167A450F78" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_369E87948E40511C67811D167A45FE3D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_E6EA0226269B4AA14AE01D167A45E429" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_369E87948E40511C67811D167A45FE3D" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_E6EA0226269B4AA14AE01D167A45E429" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_IntangibleAssetsMember" xlink:label="loc_endp_IntangibleAssetsMember_ABC57D564190F14CE5D51D221D3C0286" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_E6EA0226269B4AA14AE01D167A45E429" xlink:to="loc_endp_IntangibleAssetsMember_ABC57D564190F14CE5D51D221D3C0286" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DevelopedTechnologyRightsMember" xlink:label="loc_us-gaap_DevelopedTechnologyRightsMember_9B8B764034AF3D0C1E311D167A453709" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_E6EA0226269B4AA14AE01D167A45E429" xlink:to="loc_us-gaap_DevelopedTechnologyRightsMember_9B8B764034AF3D0C1E311D167A453709" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_StatementBusinessSegmentsAxis" xlink:label="loc_us-gaap_StatementBusinessSegmentsAxis_4F910EA8835431053BD51D167A45D5D1" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfGoodwillTable_B3C5C5D996132C4607E71D167A450F78" xlink:to="loc_us-gaap_StatementBusinessSegmentsAxis_4F910EA8835431053BD51D167A45D5D1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SegmentDomain" xlink:label="loc_us-gaap_SegmentDomain_C8FBBFE69DEF9B308B371D167A45ABCC" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_4F910EA8835431053BD51D167A45D5D1" xlink:to="loc_us-gaap_SegmentDomain_C8FBBFE69DEF9B308B371D167A45ABCC" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_FormerU.S.GenericPharmaceuticalsMember" xlink:label="loc_endp_FormerU.S.GenericPharmaceuticalsMember_F3B18E5F3CFC8849A27C1D167A45F3BB" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_C8FBBFE69DEF9B308B371D167A45ABCC" xlink:to="loc_endp_FormerU.S.GenericPharmaceuticalsMember_F3B18E5F3CFC8849A27C1D167A45F3BB" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_BrandedSterileInjectablesMember" xlink:label="loc_endp_BrandedSterileInjectablesMember_E6384998844715133DBA1D167A461B9A" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_C8FBBFE69DEF9B308B371D167A45ABCC" xlink:to="loc_endp_BrandedSterileInjectablesMember_E6384998844715133DBA1D167A461B9A" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_GenericPharmaceuticalsMember" xlink:label="loc_endp_GenericPharmaceuticalsMember_1298C362F5B4E2261C381D167A465259" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_C8FBBFE69DEF9B308B371D167A45ABCC" xlink:to="loc_endp_GenericPharmaceuticalsMember_1298C362F5B4E2261C381D167A465259" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessAcquisitionAxis" xlink:label="loc_us-gaap_BusinessAcquisitionAxis_59086C385B1B998122671D2AA0FC68F7" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfGoodwillTable_B3C5C5D996132C4607E71D167A450F78" xlink:to="loc_us-gaap_BusinessAcquisitionAxis_59086C385B1B998122671D2AA0FC68F7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_6937446FC3FF444A12521D2AA10CF50B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_59086C385B1B998122671D2AA0FC68F7" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_6937446FC3FF444A12521D2AA10CF50B" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_PaladinLabsInc.Member" xlink:label="loc_endp_PaladinLabsInc.Member_650003BB753F30387AE81D2AA15A661A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_6937446FC3FF444A12521D2AA10CF50B" xlink:to="loc_endp_PaladinLabsInc.Member_650003BB753F30387AE81D2AA15A661A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ProductOrServiceAxis" xlink:label="loc_us-gaap_ProductOrServiceAxis_4069B744F5D43764EB971D167A4666FE" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfGoodwillTable_B3C5C5D996132C4607E71D167A450F78" xlink:to="loc_us-gaap_ProductOrServiceAxis_4069B744F5D43764EB971D167A4666FE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ProductsAndServicesDomain" xlink:label="loc_us-gaap_ProductsAndServicesDomain_79C3EC2D82CC28B50F3E1D167A4627D3" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ProductOrServiceAxis_4069B744F5D43764EB971D167A4666FE" xlink:to="loc_us-gaap_ProductsAndServicesDomain_79C3EC2D82CC28B50F3E1D167A4627D3" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_SerelaxinInProcessResearchandDevelopmentIntangibleAssetsMember" xlink:label="loc_endp_SerelaxinInProcessResearchandDevelopmentIntangibleAssetsMember_D2FE4CA98B684F4984771D167A46EBDB" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ProductsAndServicesDomain_79C3EC2D82CC28B50F3E1D167A4627D3" xlink:to="loc_endp_SerelaxinInProcessResearchandDevelopmentIntangibleAssetsMember_D2FE4CA98B684F4984771D167A46EBDB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_GoodwillLineItems" xlink:label="loc_us-gaap_GoodwillLineItems_D2F34AF8CDC3985728421D167A466E9F" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfGoodwillTable_B3C5C5D996132C4607E71D167A450F78" xlink:to="loc_us-gaap_GoodwillLineItems_D2F34AF8CDC3985728421D167A466E9F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueInputsDiscountRate" xlink:label="loc_us-gaap_FairValueInputsDiscountRate_6CF9833D9AB02A7C2A1C1D167A46DEB0" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2009/role/netLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillLineItems_D2F34AF8CDC3985728421D167A466E9F" xlink:to="loc_us-gaap_FairValueInputsDiscountRate_6CF9833D9AB02A7C2A1C1D167A46DEB0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_GoodwillImpairmentLoss" xlink:label="loc_us-gaap_GoodwillImpairmentLoss_A05CFB0F333A5983AF331D167A460D72" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/netLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillLineItems_D2F34AF8CDC3985728421D167A466E9F" xlink:to="loc_us-gaap_GoodwillImpairmentLoss_A05CFB0F333A5983AF331D167A460D72" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ImpairmentOfIntangibleAssetsExcludingGoodwill" xlink:label="loc_us-gaap_ImpairmentOfIntangibleAssetsExcludingGoodwill_7676B47D5C8AD1B57E3C1D167A46DE0C" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillLineItems_D2F34AF8CDC3985728421D167A466E9F" xlink:to="loc_us-gaap_ImpairmentOfIntangibleAssetsExcludingGoodwill_7676B47D5C8AD1B57E3C1D167A46DE0C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ImpairmentOfIntangibleAssetsFinitelived" xlink:label="loc_us-gaap_ImpairmentOfIntangibleAssetsFinitelived_9E1A22EA05ABD28BEABD1D167A46C844" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillLineItems_D2F34AF8CDC3985728421D167A466E9F" xlink:to="loc_us-gaap_ImpairmentOfIntangibleAssetsFinitelived_9E1A22EA05ABD28BEABD1D167A46C844" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/GoodwillAndOtherIntangiblesOtherIntangiblesNarrativeDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract" xlink:label="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_71D2775D8C7576B1B12EF49DB8F95A35" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AmortizationOfIntangibleAssets" xlink:label="loc_us-gaap_AmortizationOfIntangibleAssets_05108A3135ED607A1F9EF49DB8FA1290" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_71D2775D8C7576B1B12EF49DB8F95A35" xlink:to="loc_us-gaap_AmortizationOfIntangibleAssets_05108A3135ED607A1F9EF49DB8FA1290" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/GoodwillAndOtherIntangiblesScheduleOfChangesInCarryingAmountOfGoodwillDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract" xlink:label="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_0B3CBAF569E4A367F75A2877F7918E33" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable" xlink:label="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_5FA11ADEA2E1F274480E2877F791C6E7" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_0B3CBAF569E4A367F75A2877F7918E33" xlink:to="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_5FA11ADEA2E1F274480E2877F791C6E7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_StatementBusinessSegmentsAxis" xlink:label="loc_us-gaap_StatementBusinessSegmentsAxis_B5F7BC45F0EE5FAC989B2877F7911358" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_5FA11ADEA2E1F274480E2877F791C6E7" xlink:to="loc_us-gaap_StatementBusinessSegmentsAxis_B5F7BC45F0EE5FAC989B2877F7911358" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SegmentDomain" xlink:label="loc_us-gaap_SegmentDomain_E33900DB0E3ADC9AA4712877F7921A13" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_B5F7BC45F0EE5FAC989B2877F7911358" xlink:to="loc_us-gaap_SegmentDomain_E33900DB0E3ADC9AA4712877F7921A13" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_BrandedSpecialtyandEstablishedPharmaceuticalsMember" xlink:label="loc_endp_BrandedSpecialtyandEstablishedPharmaceuticalsMember_7A18D3C3D6A02D869DB82877F792E5AD" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_E33900DB0E3ADC9AA4712877F7921A13" xlink:to="loc_endp_BrandedSpecialtyandEstablishedPharmaceuticalsMember_7A18D3C3D6A02D869DB82877F792E5AD" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_BrandedSterileInjectablesMember" xlink:label="loc_endp_BrandedSterileInjectablesMember_8F2E9E093A0ED33EE82A2877F7927ACD" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_E33900DB0E3ADC9AA4712877F7921A13" xlink:to="loc_endp_BrandedSterileInjectablesMember_8F2E9E093A0ED33EE82A2877F7927ACD" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_GenericPharmaceuticalsMember" xlink:label="loc_endp_GenericPharmaceuticalsMember_39E54293C333B488F85C2877F792FD7E" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_E33900DB0E3ADC9AA4712877F7921A13" xlink:to="loc_endp_GenericPharmaceuticalsMember_39E54293C333B488F85C2877F792FD7E" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_InternationalPharmaceuticalsMember" xlink:label="loc_endp_InternationalPharmaceuticalsMember_BF27668BF863AE7019D22877F7924629" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_E33900DB0E3ADC9AA4712877F7921A13" xlink:to="loc_endp_InternationalPharmaceuticalsMember_BF27668BF863AE7019D22877F7924629" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SegmentReportingInformationLineItems" xlink:label="loc_us-gaap_SegmentReportingInformationLineItems_548AE3AB7698A0F775B92877F79266B7" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_5FA11ADEA2E1F274480E2877F791C6E7" xlink:to="loc_us-gaap_SegmentReportingInformationLineItems_548AE3AB7698A0F775B92877F79266B7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_GoodwillRollForward" xlink:label="loc_us-gaap_GoodwillRollForward_581C780E6396756029542877F7922C56" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_548AE3AB7698A0F775B92877F79266B7" xlink:to="loc_us-gaap_GoodwillRollForward_581C780E6396756029542877F7922C56" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_Goodwill" xlink:label="loc_us-gaap_Goodwill_77B1D59460586A95AF2B2877F7926B19" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillRollForward_581C780E6396756029542877F7922C56" xlink:to="loc_us-gaap_Goodwill_77B1D59460586A95AF2B2877F7926B19" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_GoodwillAllocationToCurrentSegments" xlink:label="loc_endp_GoodwillAllocationToCurrentSegments_A920ACF84326B2BB27152877F792F585" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillRollForward_581C780E6396756029542877F7922C56" xlink:to="loc_endp_GoodwillAllocationToCurrentSegments_A920ACF84326B2BB27152877F792F585" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_GoodwillForeignCurrencyTranslationGainLoss" xlink:label="loc_us-gaap_GoodwillForeignCurrencyTranslationGainLoss_257B899D53D5CE68D9282877F792685A" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillRollForward_581C780E6396756029542877F7922C56" xlink:to="loc_us-gaap_GoodwillForeignCurrencyTranslationGainLoss_257B899D53D5CE68D9282877F792685A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_GoodwillImpairmentLoss" xlink:label="loc_us-gaap_GoodwillImpairmentLoss_9672D7969A9291DEE6E82877F79219F8" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillRollForward_581C780E6396756029542877F7922C56" xlink:to="loc_us-gaap_GoodwillImpairmentLoss_9672D7969A9291DEE6E82877F79219F8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_Goodwill" xlink:label="loc_us-gaap_Goodwill_F79964D82F6A23C444F52877F7928CC3" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillRollForward_581C780E6396756029542877F7922C56" xlink:to="loc_us-gaap_Goodwill_F79964D82F6A23C444F52877F7928CC3" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/GoodwillAndOtherIntangiblesScheduleOfEstimatedAmortizationOfIntangiblesDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract" xlink:label="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_5590DD5C8CD054A1885174316C0D2014" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear_430F2E1717E853DCA7717D4FFE88DA77" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_5590DD5C8CD054A1885174316C0D2014" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear_430F2E1717E853DCA7717D4FFE88DA77" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_7F145CF63040555BB96825C310435AC5" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_5590DD5C8CD054A1885174316C0D2014" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_7F145CF63040555BB96825C310435AC5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_1E42FD7ECA64545885FA96ED19935732" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_5590DD5C8CD054A1885174316C0D2014" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_1E42FD7ECA64545885FA96ED19935732" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_5D666BD32111538D99B13292617AC327" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_5590DD5C8CD054A1885174316C0D2014" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_5D666BD32111538D99B13292617AC327" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive_C1F3980324FF5A17B560035438402674" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_5590DD5C8CD054A1885174316C0D2014" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive_C1F3980324FF5A17B560035438402674" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/GoodwillAndOtherIntangiblesScheduleOfOtherIntangibleAssetsDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract" xlink:label="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_40495F6EF40E1DEA000FF49DB8F36615" xlink:type="locator" />
    <link:loc xlink:href="endp-20180331.xsd#endp_ScheduleOfGoodwillAndOtherIntangiblesTable" xlink:label="loc_endp_ScheduleOfGoodwillAndOtherIntangiblesTable_0FE7C4398EF53A605B37F49DB8F3B3B1" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_40495F6EF40E1DEA000FF49DB8F36615" xlink:to="loc_endp_ScheduleOfGoodwillAndOtherIntangiblesTable_0FE7C4398EF53A605B37F49DB8F3B3B1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RangeAxis" xlink:label="loc_us-gaap_RangeAxis_FD419913D7ACC2F15635F49DB8F4252E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_ScheduleOfGoodwillAndOtherIntangiblesTable_0FE7C4398EF53A605B37F49DB8F3B3B1" xlink:to="loc_us-gaap_RangeAxis_FD419913D7ACC2F15635F49DB8F4252E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RangeMember" xlink:label="loc_us-gaap_RangeMember_C0910F81466FC9D6E325F49DB8F4F0EA" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RangeAxis_FD419913D7ACC2F15635F49DB8F4252E" xlink:to="loc_us-gaap_RangeMember_C0910F81466FC9D6E325F49DB8F4F0EA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_WeightedAverageMember" xlink:label="loc_us-gaap_WeightedAverageMember_3C48FBD20F752315CC67F49DB8F40396" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RangeMember_C0910F81466FC9D6E325F49DB8F4F0EA" xlink:to="loc_us-gaap_WeightedAverageMember_3C48FBD20F752315CC67F49DB8F40396" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis_06ABA6EB418181557213F49DB8F40BE9" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_ScheduleOfGoodwillAndOtherIntangiblesTable_0FE7C4398EF53A605B37F49DB8F3B3B1" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis_06ABA6EB418181557213F49DB8F40BE9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_AA7469F58F4A5889F305F49DB8F4DAF4" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis_06ABA6EB418181557213F49DB8F40BE9" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_AA7469F58F4A5889F305F49DB8F4DAF4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_InProcessResearchAndDevelopmentMember" xlink:label="loc_us-gaap_InProcessResearchAndDevelopmentMember_02CC23B8C896A23FEAEEF49DB8F47D50" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_AA7469F58F4A5889F305F49DB8F4DAF4" xlink:to="loc_us-gaap_InProcessResearchAndDevelopmentMember_02CC23B8C896A23FEAEEF49DB8F47D50" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_289A170AD2B8435E161EF49DB8F4EB68" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_ScheduleOfGoodwillAndOtherIntangiblesTable_0FE7C4398EF53A605B37F49DB8F3B3B1" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_289A170AD2B8435E161EF49DB8F4EB68" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_DC545EC2D6EAFD81E489F49DB8F42C76" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_289A170AD2B8435E161EF49DB8F4EB68" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_DC545EC2D6EAFD81E489F49DB8F42C76" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LicensingAgreementsMember" xlink:label="loc_us-gaap_LicensingAgreementsMember_744A53D30BA5019B8DBFF49DB8F4B93A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_DC545EC2D6EAFD81E489F49DB8F42C76" xlink:to="loc_us-gaap_LicensingAgreementsMember_744A53D30BA5019B8DBFF49DB8F4B93A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_TradeNamesMember" xlink:label="loc_us-gaap_TradeNamesMember_083485A3BADF23085657F49DB8F48CE9" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_DC545EC2D6EAFD81E489F49DB8F42C76" xlink:to="loc_us-gaap_TradeNamesMember_083485A3BADF23085657F49DB8F48CE9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DevelopedTechnologyRightsMember" xlink:label="loc_us-gaap_DevelopedTechnologyRightsMember_607902BBBEEC000BFB6DF49DB8F4F9F4" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_DC545EC2D6EAFD81E489F49DB8F42C76" xlink:to="loc_us-gaap_DevelopedTechnologyRightsMember_607902BBBEEC000BFB6DF49DB8F4F9F4" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_OtherIntangibleAssetsLineItems" xlink:label="loc_endp_OtherIntangibleAssetsLineItems_9F2F877B8B0DE808028CF49DB8F428A8" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_ScheduleOfGoodwillAndOtherIntangiblesTable_0FE7C4398EF53A605B37F49DB8F3B3B1" xlink:to="loc_endp_OtherIntangibleAssetsLineItems_9F2F877B8B0DE808028CF49DB8F428A8" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_OtherIntangibleAssetsCostBasisAbstract" xlink:label="loc_endp_OtherIntangibleAssetsCostBasisAbstract_5CF96EA34685DF079173F49DB8F40AE6" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_OtherIntangibleAssetsLineItems_9F2F877B8B0DE808028CF49DB8F428A8" xlink:to="loc_endp_OtherIntangibleAssetsCostBasisAbstract_5CF96EA34685DF079173F49DB8F40AE6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IndefiniteLivedIntangibleAssetsRollForward" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsRollForward_B73D1988C340F1449356F49DB8F4CEAD" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_OtherIntangibleAssetsCostBasisAbstract_5CF96EA34685DF079173F49DB8F40AE6" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsRollForward_B73D1988C340F1449356F49DB8F4CEAD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill_27669F246C8C184EBC97F49DB8F4AEFC" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsRollForward_B73D1988C340F1449356F49DB8F4CEAD" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill_27669F246C8C184EBC97F49DB8F4AEFC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IndefinitelivedIntangibleAssetsAcquired" xlink:label="loc_us-gaap_IndefinitelivedIntangibleAssetsAcquired_867B2BBE1300FD75EA39F49DB8F4A936" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsRollForward_B73D1988C340F1449356F49DB8F4CEAD" xlink:to="loc_us-gaap_IndefinitelivedIntangibleAssetsAcquired_867B2BBE1300FD75EA39F49DB8F4A936" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ImpairmentOfIntangibleAssetsIndefinitelivedExcludingGoodwill" xlink:label="loc_us-gaap_ImpairmentOfIntangibleAssetsIndefinitelivedExcludingGoodwill_838D65D8AA12A6811DF1F49DB8F495E7" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsRollForward_B73D1988C340F1449356F49DB8F4CEAD" xlink:to="loc_us-gaap_ImpairmentOfIntangibleAssetsIndefinitelivedExcludingGoodwill_838D65D8AA12A6811DF1F49DB8F495E7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IndefiniteLivedIntangibleAssetsForeignCurrencyTranslationGainLoss" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsForeignCurrencyTranslationGainLoss_1F16E0DBFDD91D426740F49DB8F5B4E8" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsRollForward_B73D1988C340F1449356F49DB8F4CEAD" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsForeignCurrencyTranslationGainLoss_1F16E0DBFDD91D426740F49DB8F5B4E8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill_B03DA08D5FAF80839270F49DB8F526F9" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsRollForward_B73D1988C340F1449356F49DB8F4CEAD" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill_B03DA08D5FAF80839270F49DB8F526F9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsRollForward" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsRollForward_796FB3C4F35A2843FE9EF49DB8F5A448" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_OtherIntangibleAssetsCostBasisAbstract_5CF96EA34685DF079173F49DB8F40AE6" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsRollForward_796FB3C4F35A2843FE9EF49DB8F5A448" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsGross" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsGross_976FA09F5C65000FD8CFF49DB8F50B3A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsRollForward_796FB3C4F35A2843FE9EF49DB8F5A448" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsGross_976FA09F5C65000FD8CFF49DB8F50B3A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FinitelivedIntangibleAssetsAcquired1" xlink:label="loc_us-gaap_FinitelivedIntangibleAssetsAcquired1_51355716E1BD5123F1D7F49DB8F57370" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsRollForward_796FB3C4F35A2843FE9EF49DB8F5A448" xlink:to="loc_us-gaap_FinitelivedIntangibleAssetsAcquired1_51355716E1BD5123F1D7F49DB8F57370" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ImpairmentOfIntangibleAssetsFinitelived" xlink:label="loc_us-gaap_ImpairmentOfIntangibleAssetsFinitelived_FF968F07FB76601A81C1F49DB8F53422" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsRollForward_796FB3C4F35A2843FE9EF49DB8F5A448" xlink:to="loc_us-gaap_ImpairmentOfIntangibleAssetsFinitelived_FF968F07FB76601A81C1F49DB8F53422" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsForeignCurrencyTranslationGainLoss" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsForeignCurrencyTranslationGainLoss_CDC40065804829435679F49DB8F50D97" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsRollForward_796FB3C4F35A2843FE9EF49DB8F5A448" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsForeignCurrencyTranslationGainLoss_CDC40065804829435679F49DB8F50D97" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsGross" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsGross_EE4A9D6CF20D7BF23153F49DB8F54E67" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsRollForward_796FB3C4F35A2843FE9EF49DB8F5A448" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsGross_EE4A9D6CF20D7BF23153F49DB8F54E67" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_IntangibleAssetsGrossRollForward" xlink:label="loc_endp_IntangibleAssetsGrossRollForward_45E415C80691B09F8407F49DB8F55AA2" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_OtherIntangibleAssetsCostBasisAbstract_5CF96EA34685DF079173F49DB8F40AE6" xlink:to="loc_endp_IntangibleAssetsGrossRollForward_45E415C80691B09F8407F49DB8F55AA2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IntangibleAssetsGrossExcludingGoodwill" xlink:label="loc_us-gaap_IntangibleAssetsGrossExcludingGoodwill_690898759E8E22352839F49DB8F527B6" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_IntangibleAssetsGrossRollForward_45E415C80691B09F8407F49DB8F55AA2" xlink:to="loc_us-gaap_IntangibleAssetsGrossExcludingGoodwill_690898759E8E22352839F49DB8F527B6" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_IntangibleAssetsAcquired" xlink:label="loc_endp_IntangibleAssetsAcquired_B2A380E45EAC8523B7D4F49DB8F5552A" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_IntangibleAssetsGrossRollForward_45E415C80691B09F8407F49DB8F55AA2" xlink:to="loc_endp_IntangibleAssetsAcquired_B2A380E45EAC8523B7D4F49DB8F5552A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ImpairmentOfIntangibleAssetsExcludingGoodwill" xlink:label="loc_us-gaap_ImpairmentOfIntangibleAssetsExcludingGoodwill_5AF0659315E6D70989D4F49DB8F54392" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2009/role/negatedTotalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_IntangibleAssetsGrossRollForward_45E415C80691B09F8407F49DB8F55AA2" xlink:to="loc_us-gaap_ImpairmentOfIntangibleAssetsExcludingGoodwill_5AF0659315E6D70989D4F49DB8F54392" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_IntangibleAssetsForeignCurrencyTranslationGainLoss" xlink:label="loc_endp_IntangibleAssetsForeignCurrencyTranslationGainLoss_12321C5D48A5EDC86D61F49DB8F612D4" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_IntangibleAssetsGrossRollForward_45E415C80691B09F8407F49DB8F55AA2" xlink:to="loc_endp_IntangibleAssetsForeignCurrencyTranslationGainLoss_12321C5D48A5EDC86D61F49DB8F612D4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IntangibleAssetsGrossExcludingGoodwill" xlink:label="loc_us-gaap_IntangibleAssetsGrossExcludingGoodwill_B4170C142B710D43CFB2F49DB8F6AC44" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_IntangibleAssetsGrossRollForward_45E415C80691B09F8407F49DB8F55AA2" xlink:to="loc_us-gaap_IntangibleAssetsGrossExcludingGoodwill_B4170C142B710D43CFB2F49DB8F6AC44" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_FiniteLivedIntangibleAssetsAccumulatedAmortizationRollForward" xlink:label="loc_endp_FiniteLivedIntangibleAssetsAccumulatedAmortizationRollForward_5869B3055595A53FDCEDF49DB8F6DFB4" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_OtherIntangibleAssetsLineItems_9F2F877B8B0DE808028CF49DB8F428A8" xlink:to="loc_endp_FiniteLivedIntangibleAssetsAccumulatedAmortizationRollForward_5869B3055595A53FDCEDF49DB8F6DFB4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_DD9BB9510B27767AC682F49DB8F6C334" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2009/role/negatedPeriodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_FiniteLivedIntangibleAssetsAccumulatedAmortizationRollForward_5869B3055595A53FDCEDF49DB8F6DFB4" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_DD9BB9510B27767AC682F49DB8F6C334" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AmortizationOfIntangibleAssets" xlink:label="loc_us-gaap_AmortizationOfIntangibleAssets_4B4AAE27C5962A256E1FF49DB8F6860F" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_FiniteLivedIntangibleAssetsAccumulatedAmortizationRollForward_5869B3055595A53FDCEDF49DB8F6DFB4" xlink:to="loc_us-gaap_AmortizationOfIntangibleAssets_4B4AAE27C5962A256E1FF49DB8F6860F" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_ImpairmentofIntangibleAssetsFinitelivedEffectOnAccumulatedAmortization" xlink:label="loc_endp_ImpairmentofIntangibleAssetsFinitelivedEffectOnAccumulatedAmortization_1B3930866B16F65964F4F49DB8F6F815" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_FiniteLivedIntangibleAssetsAccumulatedAmortizationRollForward_5869B3055595A53FDCEDF49DB8F6DFB4" xlink:to="loc_endp_ImpairmentofIntangibleAssetsFinitelivedEffectOnAccumulatedAmortization_1B3930866B16F65964F4F49DB8F6F815" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_FiniteLivedIntangibleAssetsTranslationAdjustmentsEffectOnAccumulatedAmortization" xlink:label="loc_endp_FiniteLivedIntangibleAssetsTranslationAdjustmentsEffectOnAccumulatedAmortization_6444CCFC1CDAA17F1CD5F49DB8F6F279" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_FiniteLivedIntangibleAssetsAccumulatedAmortizationRollForward_5869B3055595A53FDCEDF49DB8F6DFB4" xlink:to="loc_endp_FiniteLivedIntangibleAssetsTranslationAdjustmentsEffectOnAccumulatedAmortization_6444CCFC1CDAA17F1CD5F49DB8F6F279" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_9D6C3986FEDB1A6F5D1BF49DB8F6B613" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2009/role/negatedPeriodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_FiniteLivedIntangibleAssetsAccumulatedAmortizationRollForward_5869B3055595A53FDCEDF49DB8F6DFB4" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_9D6C3986FEDB1A6F5D1BF49DB8F6B613" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IntangibleAssetsNetExcludingGoodwill" xlink:label="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_C31BFAB4C7AD56F1D540F49DB8F6DD95" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_OtherIntangibleAssetsLineItems_9F2F877B8B0DE808028CF49DB8F428A8" xlink:to="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_C31BFAB4C7AD56F1D540F49DB8F6DD95" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetUsefulLife" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetUsefulLife_CF8DBBD7A186F95E4387F49DB8F68608" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_endp_OtherIntangibleAssetsLineItems_9F2F877B8B0DE808028CF49DB8F428A8" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetUsefulLife_CF8DBBD7A186F95E4387F49DB8F68608" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/GoodwillAndOtherIntangiblesTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract" xlink:label="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_4164C96539A609BDA64DF49DB9024F50" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScheduleOfGoodwillTextBlock" xlink:label="loc_us-gaap_ScheduleOfGoodwillTextBlock_BAA69E642A1B53888204F49DB9023A76" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_4164C96539A609BDA64DF49DB9024F50" xlink:to="loc_us-gaap_ScheduleOfGoodwillTextBlock_BAA69E642A1B53888204F49DB9023A76" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_ScheduleOfOtherIntangibleAssetsTableTextBlock" xlink:label="loc_endp_ScheduleOfOtherIntangibleAssetsTableTextBlock_4C9E6C125676D2B38DC2F49DB902393F" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_4164C96539A609BDA64DF49DB9024F50" xlink:to="loc_endp_ScheduleOfOtherIntangibleAssetsTableTextBlock_4C9E6C125676D2B38DC2F49DB902393F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScheduleofFiniteLivedIntangibleAssetsFutureAmortizationExpenseTableTextBlock" xlink:label="loc_us-gaap_ScheduleofFiniteLivedIntangibleAssetsFutureAmortizationExpenseTableTextBlock_6EF1DB06C35E358A2843F49DB9027371" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_4164C96539A609BDA64DF49DB9024F50" xlink:to="loc_us-gaap_ScheduleofFiniteLivedIntangibleAssetsFutureAmortizationExpenseTableTextBlock_6EF1DB06C35E358A2843F49DB9027371" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/IncomeTaxes" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract_40A279304BBA010EDAF3F9E7F5FC6AF8" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeTaxDisclosureTextBlock" xlink:label="loc_us-gaap_IncomeTaxDisclosureTextBlock_7834F267D769130C8BC7F9E7F5FC323C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_40A279304BBA010EDAF3F9E7F5FC6AF8" xlink:to="loc_us-gaap_IncomeTaxDisclosureTextBlock_7834F267D769130C8BC7F9E7F5FC323C" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/IncomeTaxesNarrativeDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract_C477CF2726D150B892C1F8E0EC8409DD" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeTaxExpenseBenefit" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_0F03D55AC1C67DFF0465F8E0EC851E5A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_C477CF2726D150B892C1F8E0EC8409DD" xlink:to="loc_us-gaap_IncomeTaxExpenseBenefit_0F03D55AC1C67DFF0465F8E0EC851E5A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_821CB870DE0324609605F8E0EC85C7E2" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_C477CF2726D150B892C1F8E0EC8409DD" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_821CB870DE0324609605F8E0EC85C7E2" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_EffectiveIncomeTaxRateReconciliationTaxCutsandJobsActAmount" xlink:label="loc_endp_EffectiveIncomeTaxRateReconciliationTaxCutsandJobsActAmount_F23EF0AA6B1BB24E6B6CF93389CE8BCB" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_C477CF2726D150B892C1F8E0EC8409DD" xlink:to="loc_endp_EffectiveIncomeTaxRateReconciliationTaxCutsandJobsActAmount_F23EF0AA6B1BB24E6B6CF93389CE8BCB" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/Inventories" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_InventoryDisclosureAbstract" xlink:label="loc_us-gaap_InventoryDisclosureAbstract_3B32578243245CE5B2B9F1059688FC8F" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_InventoryDisclosureTextBlock" xlink:label="loc_us-gaap_InventoryDisclosureTextBlock_C435CD0131775C94909AAE0F558A7830" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InventoryDisclosureAbstract_3B32578243245CE5B2B9F1059688FC8F" xlink:to="loc_us-gaap_InventoryDisclosureTextBlock_C435CD0131775C94909AAE0F558A7830" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/InventoriesDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_InventoryDisclosureAbstract" xlink:label="loc_us-gaap_InventoryDisclosureAbstract_A2D479E0BEBF5CC9B26105D22DA7AFD5" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_InventoryRawMaterialsNetOfReserves" xlink:label="loc_us-gaap_InventoryRawMaterialsNetOfReserves_90960365EC77538387B1A7A8E916D06A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InventoryDisclosureAbstract_A2D479E0BEBF5CC9B26105D22DA7AFD5" xlink:to="loc_us-gaap_InventoryRawMaterialsNetOfReserves_90960365EC77538387B1A7A8E916D06A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_InventoryWorkInProcessNetOfReserves" xlink:label="loc_us-gaap_InventoryWorkInProcessNetOfReserves_C216195BA78752649CB40F4B8AE192AB" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InventoryDisclosureAbstract_A2D479E0BEBF5CC9B26105D22DA7AFD5" xlink:to="loc_us-gaap_InventoryWorkInProcessNetOfReserves_C216195BA78752649CB40F4B8AE192AB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_InventoryFinishedGoodsNetOfReserves" xlink:label="loc_us-gaap_InventoryFinishedGoodsNetOfReserves_DD4A44E97CB6587E930023E53C853C7C" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InventoryDisclosureAbstract_A2D479E0BEBF5CC9B26105D22DA7AFD5" xlink:to="loc_us-gaap_InventoryFinishedGoodsNetOfReserves_DD4A44E97CB6587E930023E53C853C7C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_InventoryNet" xlink:label="loc_us-gaap_InventoryNet_EEDC717F75535E19A8C0B96BD7EF2AA7" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InventoryDisclosureAbstract_A2D479E0BEBF5CC9B26105D22DA7AFD5" xlink:to="loc_us-gaap_InventoryNet_EEDC717F75535E19A8C0B96BD7EF2AA7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_InventoryNoncurrent" xlink:label="loc_us-gaap_InventoryNoncurrent_465BCB281E685821A0F99D569F5D8262" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InventoryDisclosureAbstract_A2D479E0BEBF5CC9B26105D22DA7AFD5" xlink:to="loc_us-gaap_InventoryNoncurrent_465BCB281E685821A0F99D569F5D8262" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_InventoryNotYetAvailableForSaleNet" xlink:label="loc_endp_InventoryNotYetAvailableForSaleNet_DFFBFCB2BBCF56C393E8A59EE26E0D5E" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InventoryDisclosureAbstract_A2D479E0BEBF5CC9B26105D22DA7AFD5" xlink:to="loc_endp_InventoryNotYetAvailableForSaleNet_DFFBFCB2BBCF56C393E8A59EE26E0D5E" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/InventoriesTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_InventoryDisclosureAbstract" xlink:label="loc_us-gaap_InventoryDisclosureAbstract_CE5CC4D63C345B408510ED3FEA5D28F8" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScheduleOfInventoryCurrentTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfInventoryCurrentTableTextBlock_BE71E419943B5B118BEA77D0D4EFDAD6" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InventoryDisclosureAbstract_CE5CC4D63C345B408510ED3FEA5D28F8" xlink:to="loc_us-gaap_ScheduleOfInventoryCurrentTableTextBlock_BE71E419943B5B118BEA77D0D4EFDAD6" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/NetLossPerShare" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_EarningsPerShareAbstract" xlink:label="loc_us-gaap_EarningsPerShareAbstract_6C1B7240D29E9BB02F4CF8E0ED0A07D9" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_EarningsPerShareTextBlock" xlink:label="loc_us-gaap_EarningsPerShareTextBlock_5BAB9FC63764FB50256BF8E0ED0AE912" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareAbstract_6C1B7240D29E9BB02F4CF8E0ED0A07D9" xlink:to="loc_us-gaap_EarningsPerShareTextBlock_5BAB9FC63764FB50256BF8E0ED0AE912" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/NetLossPerShareReconciliationOfNumeratorAndDenominatorOfBasicAndDilutedNetLossPerShareDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_EarningsPerShareAbstract" xlink:label="loc_us-gaap_EarningsPerShareAbstract_24DD5FA056E8696FEF8109B582A43942" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_EarningsPerShareReconciliationAbstract" xlink:label="loc_us-gaap_EarningsPerShareReconciliationAbstract_F2A3DDE3A08402714E0109B582A44B1F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareAbstract_24DD5FA056E8696FEF8109B582A43942" xlink:to="loc_us-gaap_EarningsPerShareReconciliationAbstract_F2A3DDE3A08402714E0109B582A44B1F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeLossFromContinuingOperations" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperations_A8E0D51C8ABE7FF0AA1909B582A4BA21" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareReconciliationAbstract_F2A3DDE3A08402714E0109B582A44B1F" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperations_A8E0D51C8ABE7FF0AA1909B582A4BA21" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxAttributableToReportingEntity" xlink:label="loc_us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxAttributableToReportingEntity_0C12186519DF7EBF5E8D09B582A48814" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareReconciliationAbstract_F2A3DDE3A08402714E0109B582A44B1F" xlink:to="loc_us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxAttributableToReportingEntity_0C12186519DF7EBF5E8D09B582A48814" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_NetIncomeLoss" xlink:label="loc_us-gaap_NetIncomeLoss_7358DBD1452F23681BAA09B582A4F167" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareReconciliationAbstract_F2A3DDE3A08402714E0109B582A44B1F" xlink:to="loc_us-gaap_NetIncomeLoss_7358DBD1452F23681BAA09B582A4F167" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingDilutedDisclosureItemsAbstract" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingDilutedDisclosureItemsAbstract_CC5B7FC56E0450B6469409B582A429C2" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareAbstract_24DD5FA056E8696FEF8109B582A43942" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingDilutedDisclosureItemsAbstract_CC5B7FC56E0450B6469409B582A429C2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingBasic" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_410F25282F5B9026447F09B582A4802D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingDilutedDisclosureItemsAbstract_CC5B7FC56E0450B6469409B582A429C2" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_410F25282F5B9026447F09B582A4802D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements" xlink:label="loc_us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements_1AEF237557B97DA5A0BA09B582A4B39C" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingDilutedDisclosureItemsAbstract_CC5B7FC56E0450B6469409B582A429C2" xlink:to="loc_us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements_1AEF237557B97DA5A0BA09B582A4B39C" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_DilutiveEffectOfConvertibleSeniorSubordinatedNotesAndWarrants" xlink:label="loc_endp_DilutiveEffectOfConvertibleSeniorSubordinatedNotesAndWarrants_F1664270F988785B787009D4E97D17AA" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingDilutedDisclosureItemsAbstract_CC5B7FC56E0450B6469409B582A429C2" xlink:to="loc_endp_DilutiveEffectOfConvertibleSeniorSubordinatedNotesAndWarrants_F1664270F988785B787009D4E97D17AA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding" xlink:label="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_43E2C668A188BB843EF309B582A44601" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingDilutedDisclosureItemsAbstract_CC5B7FC56E0450B6469409B582A429C2" xlink:to="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_43E2C668A188BB843EF309B582A44601" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/NetLossPerShareTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_EarningsPerShareAbstract" xlink:label="loc_us-gaap_EarningsPerShareAbstract_3DF9CEA1AA8DF7EF7C76F8E0ED098643" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock_06046DC898F7CD223569F8E0ED0901B0" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareAbstract_3DF9CEA1AA8DF7EF7C76F8E0ED098643" xlink:to="loc_us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock_06046DC898F7CD223569F8E0ED0901B0" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/OtherComprehensiveIncomeLossScheduleOfTaxEffectsAllocatedToEachComponentOfOtherComprehensiveIncomeDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_EquityAbstract" xlink:label="loc_us-gaap_EquityAbstract_82EAFB93071CAE4CE37D28D4819E1818" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossTable" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossTable_1F444B75CC0952A9467B28D4819EC037" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_82EAFB93071CAE4CE37D28D4819E1818" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossTable_1F444B75CC0952A9467B28D4819EC037" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_StatementEquityComponentsAxis" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_F4517F3086E4DB2CE3F328D4819E516A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossTable_1F444B75CC0952A9467B28D4819EC037" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_F4517F3086E4DB2CE3F328D4819E516A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_EquityComponentDomain" xlink:label="loc_us-gaap_EquityComponentDomain_A24E7CC9564DE0DF893328D4819E523E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_F4517F3086E4DB2CE3F328D4819E516A" xlink:to="loc_us-gaap_EquityComponentDomain_A24E7CC9564DE0DF893328D4819E523E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccumulatedNetInvestmentGainLossIncludingPortionAttributableToNoncontrollingInterestMember" xlink:label="loc_us-gaap_AccumulatedNetInvestmentGainLossIncludingPortionAttributableToNoncontrollingInterestMember_18F458D76D111E477A1E28D4819E7F26" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_A24E7CC9564DE0DF893328D4819E523E" xlink:to="loc_us-gaap_AccumulatedNetInvestmentGainLossIncludingPortionAttributableToNoncontrollingInterestMember_18F458D76D111E477A1E28D4819E7F26" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccumulatedForeignCurrencyAdjustmentIncludingPortionAttributableToNoncontrollingInterestMember" xlink:label="loc_us-gaap_AccumulatedForeignCurrencyAdjustmentIncludingPortionAttributableToNoncontrollingInterestMember_56164BB7E9996D03431D28D4819F2649" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_A24E7CC9564DE0DF893328D4819E523E" xlink:to="loc_us-gaap_AccumulatedForeignCurrencyAdjustmentIncludingPortionAttributableToNoncontrollingInterestMember_56164BB7E9996D03431D28D4819F2649" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_09E6DFD921B5634C993D28D4819FFF08" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossTable_1F444B75CC0952A9467B28D4819EC037" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_09E6DFD921B5634C993D28D4819FFF08" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossBeforeReclassificationsBeforeTax" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossBeforeReclassificationsBeforeTax_BBE751974FB8BB508C9928D4819FC6B9" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_09E6DFD921B5634C993D28D4819FFF08" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossBeforeReclassificationsBeforeTax_BBE751974FB8BB508C9928D4819FC6B9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossBeforeReclassificationsTax" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossBeforeReclassificationsTax_8326DA7BB7D21BE0374928D4819F81DA" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_09E6DFD921B5634C993D28D4819FFF08" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossBeforeReclassificationsTax_8326DA7BB7D21BE0374928D4819F81DA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossBeforeReclassificationsNetOfTax" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossBeforeReclassificationsNetOfTax_032B85AB63E9A2928D5928D4819F5048" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_09E6DFD921B5634C993D28D4819FFF08" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossBeforeReclassificationsNetOfTax_032B85AB63E9A2928D5928D4819F5048" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ReclassificationFromAccumulatedOtherComprehensiveIncomeCurrentPeriodBeforeTax" xlink:label="loc_us-gaap_ReclassificationFromAccumulatedOtherComprehensiveIncomeCurrentPeriodBeforeTax_B7562F1A3F88CC63365E28D4819F9E70" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_09E6DFD921B5634C993D28D4819FFF08" xlink:to="loc_us-gaap_ReclassificationFromAccumulatedOtherComprehensiveIncomeCurrentPeriodBeforeTax_B7562F1A3F88CC63365E28D4819F9E70" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ReclassificationFromAociCurrentPeriodTax" xlink:label="loc_us-gaap_ReclassificationFromAociCurrentPeriodTax_385A3F7E7DE0E6B2C6E428D4819F702D" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_09E6DFD921B5634C993D28D4819FFF08" xlink:to="loc_us-gaap_ReclassificationFromAociCurrentPeriodTax_385A3F7E7DE0E6B2C6E428D4819F702D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ReclassificationFromAccumulatedOtherComprehensiveIncomeCurrentPeriodNetOfTax" xlink:label="loc_us-gaap_ReclassificationFromAccumulatedOtherComprehensiveIncomeCurrentPeriodNetOfTax_722C92B5B8FDACF44CD328D4819F9AD9" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2009/role/negatedTotalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_09E6DFD921B5634C993D28D4819FFF08" xlink:to="loc_us-gaap_ReclassificationFromAccumulatedOtherComprehensiveIncomeCurrentPeriodNetOfTax_722C92B5B8FDACF44CD328D4819F9AD9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossBeforeTax" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossBeforeTax_7FF16A8425AF32F8A95228D4819F1E01" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_09E6DFD921B5634C993D28D4819FFF08" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossBeforeTax_7FF16A8425AF32F8A95228D4819F1E01" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossTax" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossTax_FDC8B6B38BC6766D4C9728D4819F8592" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2009/role/negatedTotalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_09E6DFD921B5634C993D28D4819FFF08" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossTax_FDC8B6B38BC6766D4C9728D4819F8592" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTax" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax_2E760B1077A1A2BD041D28D4819FDA12" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_09E6DFD921B5634C993D28D4819FFF08" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax_2E760B1077A1A2BD041D28D4819FDA12" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/OtherComprehensiveIncomeLossTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_EquityAbstract" xlink:label="loc_us-gaap_EquityAbstract_1BA99E59E09A5B96E221F49DB74B216D" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScheduleOfAmountsRecognizedInOtherComprehensiveIncomeLossTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfAmountsRecognizedInOtherComprehensiveIncomeLossTableTextBlock_B600BFE274F649C2B129F49DB74BC6E1" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_1BA99E59E09A5B96E221F49DB74B216D" xlink:to="loc_us-gaap_ScheduleOfAmountsRecognizedInOtherComprehensiveIncomeLossTableTextBlock_B600BFE274F649C2B129F49DB74BC6E1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScheduleOfAccumulatedOtherComprehensiveIncomeLossTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfAccumulatedOtherComprehensiveIncomeLossTableTextBlock_D76917615A68B4BAFA2EF49DB74BA9EA" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_1BA99E59E09A5B96E221F49DB74B216D" xlink:to="loc_us-gaap_ScheduleOfAccumulatedOtherComprehensiveIncomeLossTableTextBlock_D76917615A68B4BAFA2EF49DB74BA9EA" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/OtherComprehensiveLossIncome" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_EquityAbstract" xlink:label="loc_us-gaap_EquityAbstract_93150F2B285E316AE72AF49DB751DC01" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ComprehensiveIncomeNoteTextBlock" xlink:label="loc_us-gaap_ComprehensiveIncomeNoteTextBlock_789917B5E525E745D3A5F49DB752BA44" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_93150F2B285E316AE72AF49DB751DC01" xlink:to="loc_us-gaap_ComprehensiveIncomeNoteTextBlock_789917B5E525E745D3A5F49DB752BA44" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/OtherIncomeExpenseNetDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherIncomeAbstract" xlink:label="loc_us-gaap_OtherIncomeAbstract_359CA13C8424A4970D691D167986D3BE" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ForeignCurrencyTransactionGainLossBeforeTax" xlink:label="loc_us-gaap_ForeignCurrencyTransactionGainLossBeforeTax_79D2C5FD50320EDC25361D167987670D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherIncomeAbstract_359CA13C8424A4970D691D167986D3BE" xlink:to="loc_us-gaap_ForeignCurrencyTransactionGainLossBeforeTax_79D2C5FD50320EDC25361D167987670D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeLossFromEquityMethodInvestments" xlink:label="loc_us-gaap_IncomeLossFromEquityMethodInvestments_B8A7F3A37AD75DBA4AC91D167987B46F" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherIncomeAbstract_359CA13C8424A4970D691D167986D3BE" xlink:to="loc_us-gaap_IncomeLossFromEquityMethodInvestments_B8A7F3A37AD75DBA4AC91D167987B46F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherNonoperatingIncome" xlink:label="loc_us-gaap_OtherNonoperatingIncome_5FD907A4A5A90A3A7B341D167987FE95" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherIncomeAbstract_359CA13C8424A4970D691D167986D3BE" xlink:to="loc_us-gaap_OtherNonoperatingIncome_5FD907A4A5A90A3A7B341D167987FE95" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_NonoperatingIncomeExpense" xlink:label="loc_us-gaap_NonoperatingIncomeExpense_98AA2D17D69A61BF39601D16798700E5" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2009/role/negatedTotalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherIncomeAbstract_359CA13C8424A4970D691D167986D3BE" xlink:to="loc_us-gaap_NonoperatingIncomeExpense_98AA2D17D69A61BF39601D16798700E5" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/OtherIncomeExpenseNetTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherIncomeAbstract" xlink:label="loc_us-gaap_OtherIncomeAbstract_65BF060A2E9DF54631061D167988B99D" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScheduleOfOtherNonoperatingIncomeByComponentTextBlock" xlink:label="loc_us-gaap_ScheduleOfOtherNonoperatingIncomeByComponentTextBlock_B3180FC63FEA13B41BB11D1679888F3D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherIncomeAbstract_65BF060A2E9DF54631061D167988B99D" xlink:to="loc_us-gaap_ScheduleOfOtherNonoperatingIncomeByComponentTextBlock_B3180FC63FEA13B41BB11D1679888F3D" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/OtherIncomeNet" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherIncomeAbstract" xlink:label="loc_us-gaap_OtherIncomeAbstract_6FD1E5E2D62B7D67E9821D167989D718" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherIncomeAndOtherExpenseDisclosureTextBlock" xlink:label="loc_us-gaap_OtherIncomeAndOtherExpenseDisclosureTextBlock_EB1DB1EF6A98288F8D7E1D167989C0A5" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherIncomeAbstract_6FD1E5E2D62B7D67E9821D167989D718" xlink:to="loc_us-gaap_OtherIncomeAndOtherExpenseDisclosureTextBlock_EB1DB1EF6A98288F8D7E1D167989C0A5" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/Restructuring" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestructuringAndRelatedActivitiesAbstract" xlink:label="loc_us-gaap_RestructuringAndRelatedActivitiesAbstract_58DE4853B933582E9E006F85DB738767" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestructuringAndRelatedActivitiesDisclosureTextBlock" xlink:label="loc_us-gaap_RestructuringAndRelatedActivitiesDisclosureTextBlock_F61E5D2E2C7E52FE955C6A2E0C422B74" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringAndRelatedActivitiesAbstract_58DE4853B933582E9E006F85DB738767" xlink:to="loc_us-gaap_RestructuringAndRelatedActivitiesDisclosureTextBlock_F61E5D2E2C7E52FE955C6A2E0C422B74" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/Restructuring2017RestructuringInitiativesNarrativeDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestructuringAndRelatedActivitiesAbstract" xlink:label="loc_us-gaap_RestructuringAndRelatedActivitiesAbstract_C6EE35CE717E265E33473C6EF8015D05" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScheduleOfRestructuringAndRelatedCostsTable" xlink:label="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_0B79ED204BD54202C7643C6EF8018497" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringAndRelatedActivitiesAbstract_C6EE35CE717E265E33473C6EF8015D05" xlink:to="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_0B79ED204BD54202C7643C6EF8018497" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_StatementScenarioAxis" xlink:label="loc_us-gaap_StatementScenarioAxis_E644DD11B9E836D647A03C6EF8018CE8" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_0B79ED204BD54202C7643C6EF8018497" xlink:to="loc_us-gaap_StatementScenarioAxis_E644DD11B9E836D647A03C6EF8018CE8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScenarioUnspecifiedDomain" xlink:label="loc_us-gaap_ScenarioUnspecifiedDomain_5748BD6B4548F265ACDE3C6EF801DB03" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementScenarioAxis_E644DD11B9E836D647A03C6EF8018CE8" xlink:to="loc_us-gaap_ScenarioUnspecifiedDomain_5748BD6B4548F265ACDE3C6EF801DB03" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScenarioForecastMember" xlink:label="loc_us-gaap_ScenarioForecastMember_49B7874CBEBC7504DFB63C6EF8013B66" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScenarioUnspecifiedDomain_5748BD6B4548F265ACDE3C6EF801DB03" xlink:to="loc_us-gaap_ScenarioForecastMember_49B7874CBEBC7504DFB63C6EF8013B66" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestructuringPlanAxis" xlink:label="loc_us-gaap_RestructuringPlanAxis_534C8AC085AFA7394BE23C6EF801904B" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_0B79ED204BD54202C7643C6EF8018497" xlink:to="loc_us-gaap_RestructuringPlanAxis_534C8AC085AFA7394BE23C6EF801904B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestructuringPlanDomain" xlink:label="loc_us-gaap_RestructuringPlanDomain_54FA5C9C1380A0A73D413C6EF8019B89" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringPlanAxis_534C8AC085AFA7394BE23C6EF801904B" xlink:to="loc_us-gaap_RestructuringPlanDomain_54FA5C9C1380A0A73D413C6EF8019B89" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_January2017RestructuringMember" xlink:label="loc_endp_January2017RestructuringMember_D720ABE17421113D8B473C6EF801FC41" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringPlanDomain_54FA5C9C1380A0A73D413C6EF8019B89" xlink:to="loc_endp_January2017RestructuringMember_D720ABE17421113D8B473C6EF801FC41" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_USGenericPharmaceuticalsRestructuring2017Member" xlink:label="loc_endp_USGenericPharmaceuticalsRestructuring2017Member_30950BD23FFC2D1036923C6EF801F030" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringPlanDomain_54FA5C9C1380A0A73D413C6EF8019B89" xlink:to="loc_endp_USGenericPharmaceuticalsRestructuring2017Member_30950BD23FFC2D1036923C6EF801F030" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_January2018RestructuringMember" xlink:label="loc_endp_January2018RestructuringMember_A36E797A074C778DA1D03C6EF8018E03" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringPlanDomain_54FA5C9C1380A0A73D413C6EF8019B89" xlink:to="loc_endp_January2018RestructuringMember_A36E797A074C778DA1D03C6EF8018E03" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestructuringCostAndReserveAxis" xlink:label="loc_us-gaap_RestructuringCostAndReserveAxis_BE671E43BBEDCAC4EE883C6EF8019327" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_0B79ED204BD54202C7643C6EF8018497" xlink:to="loc_us-gaap_RestructuringCostAndReserveAxis_BE671E43BBEDCAC4EE883C6EF8019327" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_TypeOfRestructuringDomain" xlink:label="loc_us-gaap_TypeOfRestructuringDomain_FC25C40A1A8D78F586C63C6EF801F712" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringCostAndReserveAxis_BE671E43BBEDCAC4EE883C6EF8019327" xlink:to="loc_us-gaap_TypeOfRestructuringDomain_FC25C40A1A8D78F586C63C6EF801F712" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_EmployeeSeparationRetentionandOtherBenefitRelatedCostsMember" xlink:label="loc_endp_EmployeeSeparationRetentionandOtherBenefitRelatedCostsMember_95EA95960FF56A8838F73C6EF801F0BE" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfRestructuringDomain_FC25C40A1A8D78F586C63C6EF801F712" xlink:to="loc_endp_EmployeeSeparationRetentionandOtherBenefitRelatedCostsMember_95EA95960FF56A8838F73C6EF801F0BE" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_AcceleratedDepreciationMember" xlink:label="loc_endp_AcceleratedDepreciationMember_B441FC6E5D3B2DDFB9D83C6EF8017FC3" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfRestructuringDomain_FC25C40A1A8D78F586C63C6EF801F712" xlink:to="loc_endp_AcceleratedDepreciationMember_B441FC6E5D3B2DDFB9D83C6EF8017FC3" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_AssetImpairmentChargesMember" xlink:label="loc_endp_AssetImpairmentChargesMember_2003BC02EF31799E95303C6EF801B5A7" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfRestructuringDomain_FC25C40A1A8D78F586C63C6EF801F712" xlink:to="loc_endp_AssetImpairmentChargesMember_2003BC02EF31799E95303C6EF801B5A7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherRestructuringMember" xlink:label="loc_us-gaap_OtherRestructuringMember_636F768C00F90384EA7D3C6EF8011DE5" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfRestructuringDomain_FC25C40A1A8D78F586C63C6EF801F712" xlink:to="loc_us-gaap_OtherRestructuringMember_636F768C00F90384EA7D3C6EF8011DE5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_StatementBusinessSegmentsAxis" xlink:label="loc_us-gaap_StatementBusinessSegmentsAxis_D0BE2C52BEDBA1A9E5AF3C6EF801DC8C" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_0B79ED204BD54202C7643C6EF8018497" xlink:to="loc_us-gaap_StatementBusinessSegmentsAxis_D0BE2C52BEDBA1A9E5AF3C6EF801DC8C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SegmentDomain" xlink:label="loc_us-gaap_SegmentDomain_A529BDF9E3487D3E3B133C6EF80160B2" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_D0BE2C52BEDBA1A9E5AF3C6EF801DC8C" xlink:to="loc_us-gaap_SegmentDomain_A529BDF9E3487D3E3B133C6EF80160B2" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_GenericPharmaceuticalsMember" xlink:label="loc_endp_GenericPharmaceuticalsMember_2F0CB28D4D9DE6EFB4603C6EF801FC26" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_A529BDF9E3487D3E3B133C6EF80160B2" xlink:to="loc_endp_GenericPharmaceuticalsMember_2F0CB28D4D9DE6EFB4603C6EF801FC26" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_BrandedPharmaceuticalsMember" xlink:label="loc_endp_BrandedPharmaceuticalsMember_DFF5412AAD29242DBE3A3C6EF80136BD" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_A529BDF9E3487D3E3B133C6EF80160B2" xlink:to="loc_endp_BrandedPharmaceuticalsMember_DFF5412AAD29242DBE3A3C6EF80136BD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ConsolidationItemsAxis" xlink:label="loc_us-gaap_ConsolidationItemsAxis_FA178A8976B2B8C57F003C6EF8014C21" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_0B79ED204BD54202C7643C6EF8018497" xlink:to="loc_us-gaap_ConsolidationItemsAxis_FA178A8976B2B8C57F003C6EF8014C21" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ConsolidationItemsDomain" xlink:label="loc_us-gaap_ConsolidationItemsDomain_0577EB18E47D7688A2893C6EF8011FA0" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConsolidationItemsAxis_FA178A8976B2B8C57F003C6EF8014C21" xlink:to="loc_us-gaap_ConsolidationItemsDomain_0577EB18E47D7688A2893C6EF8011FA0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OperatingSegmentsMember" xlink:label="loc_us-gaap_OperatingSegmentsMember_281D8D6CFC566282486F3C6EF8012381" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConsolidationItemsDomain_0577EB18E47D7688A2893C6EF8011FA0" xlink:to="loc_us-gaap_OperatingSegmentsMember_281D8D6CFC566282486F3C6EF8012381" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_MaterialReconcilingItemsMember" xlink:label="loc_us-gaap_MaterialReconcilingItemsMember_5FE9292941833070B1213C6EF80144AD" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConsolidationItemsDomain_0577EB18E47D7688A2893C6EF8011FA0" xlink:to="loc_us-gaap_MaterialReconcilingItemsMember_5FE9292941833070B1213C6EF80144AD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestructuringCostAndReserveLineItems" xlink:label="loc_us-gaap_RestructuringCostAndReserveLineItems_A02A33AF4D70AF63DBD33C6EF801C1EC" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_0B79ED204BD54202C7643C6EF8018497" xlink:to="loc_us-gaap_RestructuringCostAndReserveLineItems_A02A33AF4D70AF63DBD33C6EF801C1EC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestructuringAndRelatedCostExpectedNumberOfPositionsEliminated" xlink:label="loc_us-gaap_RestructuringAndRelatedCostExpectedNumberOfPositionsEliminated_C998197F75730F9773063C6EF80131B4" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringCostAndReserveLineItems_A02A33AF4D70AF63DBD33C6EF801C1EC" xlink:to="loc_us-gaap_RestructuringAndRelatedCostExpectedNumberOfPositionsEliminated_C998197F75730F9773063C6EF80131B4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestructuringCharges" xlink:label="loc_us-gaap_RestructuringCharges_2555EAB7332997E698EA3C6EF8013384" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringCostAndReserveLineItems_A02A33AF4D70AF63DBD33C6EF801C1EC" xlink:to="loc_us-gaap_RestructuringCharges_2555EAB7332997E698EA3C6EF8013384" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestructuringCostsAndAssetImpairmentCharges" xlink:label="loc_us-gaap_RestructuringCostsAndAssetImpairmentCharges_F3D3B39DCBE099A014753C6EF8010CE1" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringCostAndReserveLineItems_A02A33AF4D70AF63DBD33C6EF801C1EC" xlink:to="loc_us-gaap_RestructuringCostsAndAssetImpairmentCharges_F3D3B39DCBE099A014753C6EF8010CE1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestructuringAndRelatedCostExpectedCost1" xlink:label="loc_us-gaap_RestructuringAndRelatedCostExpectedCost1_C081CBAE2C9F6D2A34743C6EF801A6C4" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringCostAndReserveLineItems_A02A33AF4D70AF63DBD33C6EF801C1EC" xlink:to="loc_us-gaap_RestructuringAndRelatedCostExpectedCost1_C081CBAE2C9F6D2A34743C6EF801A6C4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestructuringAndRelatedCostExpectedCostRemaining1" xlink:label="loc_us-gaap_RestructuringAndRelatedCostExpectedCostRemaining1_1ACE0F44681F9F0C17C73C6EF801D76A" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringCostAndReserveLineItems_A02A33AF4D70AF63DBD33C6EF801C1EC" xlink:to="loc_us-gaap_RestructuringAndRelatedCostExpectedCostRemaining1_1ACE0F44681F9F0C17C73C6EF801D76A" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/RestructuringJanuary2018RestructuringInitiativeNarrativeDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestructuringAndRelatedActivitiesAbstract" xlink:label="loc_us-gaap_RestructuringAndRelatedActivitiesAbstract_6D8B41C9AE5B5B5507CB2877F81557B6" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScheduleOfRestructuringAndRelatedCostsTable" xlink:label="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_B25102E302CFF7F5DA672877F815AA25" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringAndRelatedActivitiesAbstract_6D8B41C9AE5B5B5507CB2877F81557B6" xlink:to="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_B25102E302CFF7F5DA672877F815AA25" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_StatementScenarioAxis" xlink:label="loc_us-gaap_StatementScenarioAxis_307EB4BAF37794DEC6C52877F81571B8" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_B25102E302CFF7F5DA672877F815AA25" xlink:to="loc_us-gaap_StatementScenarioAxis_307EB4BAF37794DEC6C52877F81571B8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScenarioUnspecifiedDomain" xlink:label="loc_us-gaap_ScenarioUnspecifiedDomain_5562BC651E9356B1A6602877F8151871" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementScenarioAxis_307EB4BAF37794DEC6C52877F81571B8" xlink:to="loc_us-gaap_ScenarioUnspecifiedDomain_5562BC651E9356B1A6602877F8151871" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScenarioForecastMember" xlink:label="loc_us-gaap_ScenarioForecastMember_4BE87BCC5D8EB8A616E82877F81555F5" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScenarioUnspecifiedDomain_5562BC651E9356B1A6602877F8151871" xlink:to="loc_us-gaap_ScenarioForecastMember_4BE87BCC5D8EB8A616E82877F81555F5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ConsolidationItemsAxis" xlink:label="loc_us-gaap_ConsolidationItemsAxis_A545E7432F4C5ADF05062877F8158AF7" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_B25102E302CFF7F5DA672877F815AA25" xlink:to="loc_us-gaap_ConsolidationItemsAxis_A545E7432F4C5ADF05062877F8158AF7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ConsolidationItemsDomain" xlink:label="loc_us-gaap_ConsolidationItemsDomain_B177A6B1B8203BED48AC2877F8159E12" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConsolidationItemsAxis_A545E7432F4C5ADF05062877F8158AF7" xlink:to="loc_us-gaap_ConsolidationItemsDomain_B177A6B1B8203BED48AC2877F8159E12" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_MaterialReconcilingItemsMember" xlink:label="loc_us-gaap_MaterialReconcilingItemsMember_3A27E9E6075A74227A232877F8155AFD" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConsolidationItemsDomain_B177A6B1B8203BED48AC2877F8159E12" xlink:to="loc_us-gaap_MaterialReconcilingItemsMember_3A27E9E6075A74227A232877F8155AFD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OperatingSegmentsMember" xlink:label="loc_us-gaap_OperatingSegmentsMember_6DF26B9B210693438A5E2877F8158C13" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConsolidationItemsDomain_B177A6B1B8203BED48AC2877F8159E12" xlink:to="loc_us-gaap_OperatingSegmentsMember_6DF26B9B210693438A5E2877F8158C13" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_StatementBusinessSegmentsAxis" xlink:label="loc_us-gaap_StatementBusinessSegmentsAxis_54D155AE42B7271E890B2877F815D3C3" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_B25102E302CFF7F5DA672877F815AA25" xlink:to="loc_us-gaap_StatementBusinessSegmentsAxis_54D155AE42B7271E890B2877F815D3C3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SegmentDomain" xlink:label="loc_us-gaap_SegmentDomain_D07C98CFAEB0847294CC2877F815CD74" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_54D155AE42B7271E890B2877F815D3C3" xlink:to="loc_us-gaap_SegmentDomain_D07C98CFAEB0847294CC2877F815CD74" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_GenericPharmaceuticalsMember" xlink:label="loc_endp_GenericPharmaceuticalsMember_E86A139065460A6715862877F815CA4B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_D07C98CFAEB0847294CC2877F815CD74" xlink:to="loc_endp_GenericPharmaceuticalsMember_E86A139065460A6715862877F815CA4B" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_BrandedSterileInjectablesMember" xlink:label="loc_endp_BrandedSterileInjectablesMember_430BDBC18A7E07B9013B2877F815785C" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_D07C98CFAEB0847294CC2877F815CD74" xlink:to="loc_endp_BrandedSterileInjectablesMember_430BDBC18A7E07B9013B2877F815785C" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_InternationalPharmaceuticalsMember" xlink:label="loc_endp_InternationalPharmaceuticalsMember_CA29EDF8387EBBBE76102877F8155376" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_D07C98CFAEB0847294CC2877F815CD74" xlink:to="loc_endp_InternationalPharmaceuticalsMember_CA29EDF8387EBBBE76102877F8155376" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_BrandedSpecialtyandEstablishedPharmaceuticalsMember" xlink:label="loc_endp_BrandedSpecialtyandEstablishedPharmaceuticalsMember_2AEC7714627B0B0DD1AE2877F81555CC" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_D07C98CFAEB0847294CC2877F815CD74" xlink:to="loc_endp_BrandedSpecialtyandEstablishedPharmaceuticalsMember_2AEC7714627B0B0DD1AE2877F81555CC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestructuringCostAndReserveAxis" xlink:label="loc_us-gaap_RestructuringCostAndReserveAxis_3C7539D2121E2493FB632877F81570D5" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_B25102E302CFF7F5DA672877F815AA25" xlink:to="loc_us-gaap_RestructuringCostAndReserveAxis_3C7539D2121E2493FB632877F81570D5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_TypeOfRestructuringDomain" xlink:label="loc_us-gaap_TypeOfRestructuringDomain_B3F90D03A48C7B732E9F2877F815E0D7" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringCostAndReserveAxis_3C7539D2121E2493FB632877F81570D5" xlink:to="loc_us-gaap_TypeOfRestructuringDomain_B3F90D03A48C7B732E9F2877F815E0D7" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_EmployeeSeparationRetentionandOtherBenefitRelatedCostsMember" xlink:label="loc_endp_EmployeeSeparationRetentionandOtherBenefitRelatedCostsMember_CC81F8BB14B36E1018372877F81584E3" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfRestructuringDomain_B3F90D03A48C7B732E9F2877F815E0D7" xlink:to="loc_endp_EmployeeSeparationRetentionandOtherBenefitRelatedCostsMember_CC81F8BB14B36E1018372877F81584E3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherRestructuringMember" xlink:label="loc_us-gaap_OtherRestructuringMember_FB6C9E2F96C5A9AA4DAB2877F8155E0F" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfRestructuringDomain_B3F90D03A48C7B732E9F2877F815E0D7" xlink:to="loc_us-gaap_OtherRestructuringMember_FB6C9E2F96C5A9AA4DAB2877F8155E0F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestructuringPlanAxis" xlink:label="loc_us-gaap_RestructuringPlanAxis_5959634CACFE64FAF2F42877F8157B5E" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_B25102E302CFF7F5DA672877F815AA25" xlink:to="loc_us-gaap_RestructuringPlanAxis_5959634CACFE64FAF2F42877F8157B5E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestructuringPlanDomain" xlink:label="loc_us-gaap_RestructuringPlanDomain_8710D22CD283FB4D3BCB2877F8153B5B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringPlanAxis_5959634CACFE64FAF2F42877F8157B5E" xlink:to="loc_us-gaap_RestructuringPlanDomain_8710D22CD283FB4D3BCB2877F8153B5B" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_January2018RestructuringMember" xlink:label="loc_endp_January2018RestructuringMember_7E92A4AA53D1AC0618A92877F815F4DD" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringPlanDomain_8710D22CD283FB4D3BCB2877F8153B5B" xlink:to="loc_endp_January2018RestructuringMember_7E92A4AA53D1AC0618A92877F815F4DD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestructuringCostAndReserveLineItems" xlink:label="loc_us-gaap_RestructuringCostAndReserveLineItems_60E7EE53D8C1226C08182877F8154CB6" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_B25102E302CFF7F5DA672877F815AA25" xlink:to="loc_us-gaap_RestructuringCostAndReserveLineItems_60E7EE53D8C1226C08182877F8154CB6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestructuringAndRelatedCostExpectedCost1" xlink:label="loc_us-gaap_RestructuringAndRelatedCostExpectedCost1_92CE1BD08372BBE5F41B2877F815A325" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringCostAndReserveLineItems_60E7EE53D8C1226C08182877F8154CB6" xlink:to="loc_us-gaap_RestructuringAndRelatedCostExpectedCost1_92CE1BD08372BBE5F41B2877F815A325" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_RestructuringandRelatedCostEstimatedCashPayments" xlink:label="loc_endp_RestructuringandRelatedCostEstimatedCashPayments_4EFC51241B7218BF676B2877F81500D6" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringCostAndReserveLineItems_60E7EE53D8C1226C08182877F8154CB6" xlink:to="loc_endp_RestructuringandRelatedCostEstimatedCashPayments_4EFC51241B7218BF676B2877F81500D6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestructuringCharges" xlink:label="loc_us-gaap_RestructuringCharges_501C01F6FF5AC2CC9A8B2877F815CEFB" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringCostAndReserveLineItems_60E7EE53D8C1226C08182877F8154CB6" xlink:to="loc_us-gaap_RestructuringCharges_501C01F6FF5AC2CC9A8B2877F815CEFB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestructuringCostsAndAssetImpairmentCharges" xlink:label="loc_us-gaap_RestructuringCostsAndAssetImpairmentCharges_27F5C4C5E0C4F85DFB4A2877F815B09A" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringCostAndReserveLineItems_60E7EE53D8C1226C08182877F8154CB6" xlink:to="loc_us-gaap_RestructuringCostsAndAssetImpairmentCharges_27F5C4C5E0C4F85DFB4A2877F815B09A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestructuringAndRelatedCostExpectedCostRemaining1" xlink:label="loc_us-gaap_RestructuringAndRelatedCostExpectedCostRemaining1_267DAF809974A2E4FC242877F8157025" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringCostAndReserveLineItems_60E7EE53D8C1226C08182877F8154CB6" xlink:to="loc_us-gaap_RestructuringAndRelatedCostExpectedCostRemaining1_267DAF809974A2E4FC242877F8157025" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/RestructuringScheduleOfRestructuringRollForwardDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestructuringAndRelatedActivitiesAbstract" xlink:label="loc_us-gaap_RestructuringAndRelatedActivitiesAbstract_AD13CE6C4A556FB988533C57136F2512" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScheduleOfRestructuringAndRelatedCostsTable" xlink:label="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_0A0887765F6CA8FAFB803C57136FA956" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringAndRelatedActivitiesAbstract_AD13CE6C4A556FB988533C57136F2512" xlink:to="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_0A0887765F6CA8FAFB803C57136FA956" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestructuringPlanAxis" xlink:label="loc_us-gaap_RestructuringPlanAxis_CB39E96EB9DC18D0EC483C57136FA6F1" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_0A0887765F6CA8FAFB803C57136FA956" xlink:to="loc_us-gaap_RestructuringPlanAxis_CB39E96EB9DC18D0EC483C57136FA6F1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestructuringPlanDomain" xlink:label="loc_us-gaap_RestructuringPlanDomain_B7A9F0A3A6DDD5F559653C57136FC5F5" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringPlanAxis_CB39E96EB9DC18D0EC483C57136FA6F1" xlink:to="loc_us-gaap_RestructuringPlanDomain_B7A9F0A3A6DDD5F559653C57136FC5F5" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_USGenericPharmaceuticalsRestructuring2017Member" xlink:label="loc_endp_USGenericPharmaceuticalsRestructuring2017Member_A4E9D0E16BD4710C09183C8A8675258B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringPlanDomain_B7A9F0A3A6DDD5F559653C57136FC5F5" xlink:to="loc_endp_USGenericPharmaceuticalsRestructuring2017Member_A4E9D0E16BD4710C09183C8A8675258B" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_January2018RestructuringMember" xlink:label="loc_endp_January2018RestructuringMember_22FBAF5E9954D87876533C57136FF96C" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringPlanDomain_B7A9F0A3A6DDD5F559653C57136FC5F5" xlink:to="loc_endp_January2018RestructuringMember_22FBAF5E9954D87876533C57136FF96C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestructuringCostAndReserveAxis" xlink:label="loc_us-gaap_RestructuringCostAndReserveAxis_C0BFA379D3ACAE4ECDA73C57136FC4FC" xlink:type="locator" />
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_0A0887765F6CA8FAFB803C57136FA956" xlink:to="loc_us-gaap_RestructuringCostAndReserveAxis_C0BFA379D3ACAE4ECDA73C57136FC4FC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_TypeOfRestructuringDomain" xlink:label="loc_us-gaap_TypeOfRestructuringDomain_BB72C11A525D862D2C263C57136FF1E0" xlink:type="locator" />
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringCostAndReserveAxis_C0BFA379D3ACAE4ECDA73C57136FC4FC" xlink:to="loc_us-gaap_TypeOfRestructuringDomain_BB72C11A525D862D2C263C57136FF1E0" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_EmployeeSeverenceandOtherBenefitRelatedCostsMember" xlink:label="loc_endp_EmployeeSeverenceandOtherBenefitRelatedCostsMember_2349B4C21D7679BCBE803C57136F2392" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfRestructuringDomain_BB72C11A525D862D2C263C57136FF1E0" xlink:to="loc_endp_EmployeeSeverenceandOtherBenefitRelatedCostsMember_2349B4C21D7679BCBE803C57136F2392" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherRestructuringMember" xlink:label="loc_us-gaap_OtherRestructuringMember_6880031ECF80080214DA3C57136FA415" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/netLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfRestructuringDomain_BB72C11A525D862D2C263C57136FF1E0" xlink:to="loc_us-gaap_OtherRestructuringMember_6880031ECF80080214DA3C57136FA415" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestructuringCostAndReserveLineItems" xlink:label="loc_us-gaap_RestructuringCostAndReserveLineItems_EDD6C601ADE694BDBB503C57136FBFD3" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_0A0887765F6CA8FAFB803C57136FA956" xlink:to="loc_us-gaap_RestructuringCostAndReserveLineItems_EDD6C601ADE694BDBB503C57136FBFD3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestructuringReserveRollForward" xlink:label="loc_us-gaap_RestructuringReserveRollForward_D1C032ED9FD7E54B7D293C57136FEA62" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringCostAndReserveLineItems_EDD6C601ADE694BDBB503C57136FBFD3" xlink:to="loc_us-gaap_RestructuringReserveRollForward_D1C032ED9FD7E54B7D293C57136FEA62" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestructuringReserve" xlink:label="loc_us-gaap_RestructuringReserve_C05E3BBF173F8395CAC73C57136F79A4" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringReserveRollForward_D1C032ED9FD7E54B7D293C57136FEA62" xlink:to="loc_us-gaap_RestructuringReserve_C05E3BBF173F8395CAC73C57136F79A4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestructuringCharges" xlink:label="loc_us-gaap_RestructuringCharges_77F2A84FE6F63F127E1F3C57136FBF41" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringReserveRollForward_D1C032ED9FD7E54B7D293C57136FEA62" xlink:to="loc_us-gaap_RestructuringCharges_77F2A84FE6F63F127E1F3C57136FBF41" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_PaymentsForRestructuring" xlink:label="loc_us-gaap_PaymentsForRestructuring_B38537354F088C539F0F3C57136F183B" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringReserveRollForward_D1C032ED9FD7E54B7D293C57136FEA62" xlink:to="loc_us-gaap_PaymentsForRestructuring_B38537354F088C539F0F3C57136F183B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestructuringReserve" xlink:label="loc_us-gaap_RestructuringReserve_99F871B9C1A74BAB2E463C57136F4D29" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringReserveRollForward_D1C032ED9FD7E54B7D293C57136FEA62" xlink:to="loc_us-gaap_RestructuringReserve_99F871B9C1A74BAB2E463C57136F4D29" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/RestructuringTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestructuringAndRelatedActivitiesAbstract" xlink:label="loc_us-gaap_RestructuringAndRelatedActivitiesAbstract_6C4B088215AB5717E588F029ACDDFC07" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScheduleOfRestructuringReserveByTypeOfCostTextBlock" xlink:label="loc_us-gaap_ScheduleOfRestructuringReserveByTypeOfCostTextBlock_E5938D0F9F4F220AA392F029ACDDD540" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringAndRelatedActivitiesAbstract_6C4B088215AB5717E588F029ACDDFC07" xlink:to="loc_us-gaap_ScheduleOfRestructuringReserveByTypeOfCostTextBlock_E5938D0F9F4F220AA392F029ACDDD540" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/SegmentResults" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SegmentReportingAbstract" xlink:label="loc_us-gaap_SegmentReportingAbstract_9BB0CF9AB55D5A768BD21CAFA4E2A71B" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SegmentReportingDisclosureTextBlock" xlink:label="loc_us-gaap_SegmentReportingDisclosureTextBlock_E5AA447959BD549AB2C8277718B3D626" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingAbstract_9BB0CF9AB55D5A768BD21CAFA4E2A71B" xlink:to="loc_us-gaap_SegmentReportingDisclosureTextBlock_E5AA447959BD549AB2C8277718B3D626" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/SegmentResultsScheduleOfDisaggregationOfRevenuesDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SegmentReportingAbstract" xlink:label="loc_us-gaap_SegmentReportingAbstract_C417095FE4CB1962CEDAF8E0EDFA88DC" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DisaggregationOfRevenueTable" xlink:label="loc_us-gaap_DisaggregationOfRevenueTable_FFBBB05E1DB1D68AB0EAF8E0EDFAF2B2" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingAbstract_C417095FE4CB1962CEDAF8E0EDFA88DC" xlink:to="loc_us-gaap_DisaggregationOfRevenueTable_FFBBB05E1DB1D68AB0EAF8E0EDFAF2B2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ProductOrServiceAxis" xlink:label="loc_us-gaap_ProductOrServiceAxis_144F1F8B515AD8A0F635F8E0EDFA6A37" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisaggregationOfRevenueTable_FFBBB05E1DB1D68AB0EAF8E0EDFAF2B2" xlink:to="loc_us-gaap_ProductOrServiceAxis_144F1F8B515AD8A0F635F8E0EDFA6A37" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ProductsAndServicesDomain" xlink:label="loc_us-gaap_ProductsAndServicesDomain_3E860DC0CEC6895B71DFF8E0EDFAC2FA" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ProductOrServiceAxis_144F1F8B515AD8A0F635F8E0EDFA6A37" xlink:to="loc_us-gaap_ProductsAndServicesDomain_3E860DC0CEC6895B71DFF8E0EDFAC2FA" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_XiaflexMember" xlink:label="loc_endp_XiaflexMember_A46CD86F6F9498BD8BA2F8E0EDFBF1CA" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ProductsAndServicesDomain_3E860DC0CEC6895B71DFF8E0EDFAC2FA" xlink:to="loc_endp_XiaflexMember_A46CD86F6F9498BD8BA2F8E0EDFBF1CA" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_SUPPRELINLAMember" xlink:label="loc_endp_SUPPRELINLAMember_5D5CF1F9AA85A50BFD12F8E0EDFB50AE" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ProductsAndServicesDomain_3E860DC0CEC6895B71DFF8E0EDFAC2FA" xlink:to="loc_endp_SUPPRELINLAMember_5D5CF1F9AA85A50BFD12F8E0EDFB50AE" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_OtherSpecialtyProductsMember" xlink:label="loc_endp_OtherSpecialtyProductsMember_B0A0ED6F798A5D1C6A8EF8E0EDFBA4BA" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ProductsAndServicesDomain_3E860DC0CEC6895B71DFF8E0EDFAC2FA" xlink:to="loc_endp_OtherSpecialtyProductsMember_B0A0ED6F798A5D1C6A8EF8E0EDFBA4BA" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_TotalSpecialtyProductsMember" xlink:label="loc_endp_TotalSpecialtyProductsMember_EF1F85F3434C98E5347AF8E0EDFBEF3A" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ProductsAndServicesDomain_3E860DC0CEC6895B71DFF8E0EDFAC2FA" xlink:to="loc_endp_TotalSpecialtyProductsMember_EF1F85F3434C98E5347AF8E0EDFBEF3A" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_PERCOCETMember" xlink:label="loc_endp_PERCOCETMember_07B39A3ADE1B867712BEF8E0EDFB3425" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ProductsAndServicesDomain_3E860DC0CEC6895B71DFF8E0EDFAC2FA" xlink:to="loc_endp_PERCOCETMember_07B39A3ADE1B867712BEF8E0EDFB3425" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_VoltarenGelMember" xlink:label="loc_endp_VoltarenGelMember_91231E9B5082A9CC90E9F8E0EDFB55BC" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ProductsAndServicesDomain_3E860DC0CEC6895B71DFF8E0EDFAC2FA" xlink:to="loc_endp_VoltarenGelMember_91231E9B5082A9CC90E9F8E0EDFB55BC" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_OpanaMember" xlink:label="loc_endp_OpanaMember_9AB445A6FFFAFE167DF5F8E0EDFB9767" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ProductsAndServicesDomain_3E860DC0CEC6895B71DFF8E0EDFAC2FA" xlink:to="loc_endp_OpanaMember_9AB445A6FFFAFE167DF5F8E0EDFB9767" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_OtherEstablishedProductsMember" xlink:label="loc_endp_OtherEstablishedProductsMember_1A89BB6A3B1C13731F91F8E0EDFB990B" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ProductsAndServicesDomain_3E860DC0CEC6895B71DFF8E0EDFAC2FA" xlink:to="loc_endp_OtherEstablishedProductsMember_1A89BB6A3B1C13731F91F8E0EDFB990B" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_EstablishedProductsMember" xlink:label="loc_endp_EstablishedProductsMember_3B641EBCA1F097B50CD7F8E0EDFB391E" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ProductsAndServicesDomain_3E860DC0CEC6895B71DFF8E0EDFAC2FA" xlink:to="loc_endp_EstablishedProductsMember_3B641EBCA1F097B50CD7F8E0EDFB391E" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_VasostrictMember" xlink:label="loc_endp_VasostrictMember_9E8B0CD5889BB1152CDAF8E0EDFB6E1A" xlink:type="locator" />
    <link:presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ProductsAndServicesDomain_3E860DC0CEC6895B71DFF8E0EDFAC2FA" xlink:to="loc_endp_VasostrictMember_9E8B0CD5889BB1152CDAF8E0EDFB6E1A" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_AdrenalinMember" xlink:label="loc_endp_AdrenalinMember_BFCE2CD5B9145C62CAC1F8E0EDFB8D8A" xlink:type="locator" />
    <link:presentationArc order="11" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ProductsAndServicesDomain_3E860DC0CEC6895B71DFF8E0EDFAC2FA" xlink:to="loc_endp_AdrenalinMember_BFCE2CD5B9145C62CAC1F8E0EDFB8D8A" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_OtherSterileInjectablesMember" xlink:label="loc_endp_OtherSterileInjectablesMember_1D38C7695D10831FC398F8E0EDFBA188" xlink:type="locator" />
    <link:presentationArc order="12" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ProductsAndServicesDomain_3E860DC0CEC6895B71DFF8E0EDFAC2FA" xlink:to="loc_endp_OtherSterileInjectablesMember_1D38C7695D10831FC398F8E0EDFBA188" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_StatementBusinessSegmentsAxis" xlink:label="loc_us-gaap_StatementBusinessSegmentsAxis_D9F8104354C21B1EE07EF8E0EDFBA039" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisaggregationOfRevenueTable_FFBBB05E1DB1D68AB0EAF8E0EDFAF2B2" xlink:to="loc_us-gaap_StatementBusinessSegmentsAxis_D9F8104354C21B1EE07EF8E0EDFBA039" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SegmentDomain" xlink:label="loc_us-gaap_SegmentDomain_8E6B6030014F13080979F8E0EDFBBC22" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_D9F8104354C21B1EE07EF8E0EDFBA039" xlink:to="loc_us-gaap_SegmentDomain_8E6B6030014F13080979F8E0EDFBBC22" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_BrandedSpecialtyandEstablishedPharmaceuticalsMember" xlink:label="loc_endp_BrandedSpecialtyandEstablishedPharmaceuticalsMember_C4E9711D6B134671DE34F8E0EDFB3DA1" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_8E6B6030014F13080979F8E0EDFBBC22" xlink:to="loc_endp_BrandedSpecialtyandEstablishedPharmaceuticalsMember_C4E9711D6B134671DE34F8E0EDFB3DA1" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_BrandedSterileInjectablesMember" xlink:label="loc_endp_BrandedSterileInjectablesMember_BA1A4325E4894C4D3FA0F8E0EDFBE927" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_8E6B6030014F13080979F8E0EDFBBC22" xlink:to="loc_endp_BrandedSterileInjectablesMember_BA1A4325E4894C4D3FA0F8E0EDFBE927" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_GenericPharmaceuticalsMember" xlink:label="loc_endp_GenericPharmaceuticalsMember_68B50640339685C7DC81F8E0EDFB806E" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_8E6B6030014F13080979F8E0EDFBBC22" xlink:to="loc_endp_GenericPharmaceuticalsMember_68B50640339685C7DC81F8E0EDFB806E" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_InternationalPharmaceuticalsMember" xlink:label="loc_endp_InternationalPharmaceuticalsMember_6B73994E0B0A7CAFCD77F8E0EDFBE5FA" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_8E6B6030014F13080979F8E0EDFBBC22" xlink:to="loc_endp_InternationalPharmaceuticalsMember_6B73994E0B0A7CAFCD77F8E0EDFBE5FA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DisaggregationOfRevenueLineItems" xlink:label="loc_us-gaap_DisaggregationOfRevenueLineItems_1791511DFFC7B0DBFDD2F8E0EDFB4909" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisaggregationOfRevenueTable_FFBBB05E1DB1D68AB0EAF8E0EDFAF2B2" xlink:to="loc_us-gaap_DisaggregationOfRevenueLineItems_1791511DFFC7B0DBFDD2F8E0EDFB4909" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_Revenues" xlink:label="loc_us-gaap_Revenues_DCBDF8E4E3C128449AF5F8E0EDFB3097" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisaggregationOfRevenueLineItems_1791511DFFC7B0DBFDD2F8E0EDFB4909" xlink:to="loc_us-gaap_Revenues_DCBDF8E4E3C128449AF5F8E0EDFB3097" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_ProductLineRevenueReportingThreshold" xlink:label="loc_endp_ProductLineRevenueReportingThreshold_10EED05123C1625A48BEF8E0EDFBC325" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisaggregationOfRevenueLineItems_1791511DFFC7B0DBFDD2F8E0EDFB4909" xlink:to="loc_endp_ProductLineRevenueReportingThreshold_10EED05123C1625A48BEF8E0EDFBC325" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ConcentrationRiskPercentage1" xlink:label="loc_us-gaap_ConcentrationRiskPercentage1_26E6167A5CD38ED3DC4BF8E0EDFBE5CD" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisaggregationOfRevenueLineItems_1791511DFFC7B0DBFDD2F8E0EDFB4909" xlink:to="loc_us-gaap_ConcentrationRiskPercentage1_26E6167A5CD38ED3DC4BF8E0EDFBE5CD" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/SegmentResultsScheduleOfReconciliationsOfConsolidatedAdjustedIncomeLossBeforeIncomeTaxDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SegmentReportingAbstract" xlink:label="loc_us-gaap_SegmentReportingAbstract_6600A37D2C8E08F0C2C409B585133A62" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable" xlink:label="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_514413063999678B0CAB09B585137E1D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingAbstract_6600A37D2C8E08F0C2C409B585133A62" xlink:to="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_514413063999678B0CAB09B585137E1D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ConsolidationItemsAxis" xlink:label="loc_us-gaap_ConsolidationItemsAxis_C5EF54C14E59ED5EB53009B585135E8A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_514413063999678B0CAB09B585137E1D" xlink:to="loc_us-gaap_ConsolidationItemsAxis_C5EF54C14E59ED5EB53009B585135E8A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ConsolidationItemsDomain" xlink:label="loc_us-gaap_ConsolidationItemsDomain_366FC40D23F53B5D88C709B58513B993" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConsolidationItemsAxis_C5EF54C14E59ED5EB53009B585135E8A" xlink:to="loc_us-gaap_ConsolidationItemsDomain_366FC40D23F53B5D88C709B58513B993" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_MaterialReconcilingItemsMember" xlink:label="loc_us-gaap_MaterialReconcilingItemsMember_D2D45774802F6750C64B09B58513D82A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConsolidationItemsDomain_366FC40D23F53B5D88C709B58513B993" xlink:to="loc_us-gaap_MaterialReconcilingItemsMember_D2D45774802F6750C64B09B58513D82A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OperatingSegmentsMember" xlink:label="loc_us-gaap_OperatingSegmentsMember_468786EDCCA7C21BC37509B585136C06" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConsolidationItemsDomain_366FC40D23F53B5D88C709B58513B993" xlink:to="loc_us-gaap_OperatingSegmentsMember_468786EDCCA7C21BC37509B585136C06" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestructuringCostAndReserveAxis" xlink:label="loc_us-gaap_RestructuringCostAndReserveAxis_DD2E2BFB763EAEC329F809B585134AC9" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_514413063999678B0CAB09B585137E1D" xlink:to="loc_us-gaap_RestructuringCostAndReserveAxis_DD2E2BFB763EAEC329F809B585134AC9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_TypeOfRestructuringDomain" xlink:label="loc_us-gaap_TypeOfRestructuringDomain_9895618E49E3EB05AF4109B58513EB0C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringCostAndReserveAxis_DD2E2BFB763EAEC329F809B585134AC9" xlink:to="loc_us-gaap_TypeOfRestructuringDomain_9895618E49E3EB05AF4109B58513EB0C" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_InventoryWriteOffsMember" xlink:label="loc_endp_InventoryWriteOffsMember_B8430D47AA6B0D1A905E09B58514758C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfRestructuringDomain_9895618E49E3EB05AF4109B58513EB0C" xlink:to="loc_endp_InventoryWriteOffsMember_B8430D47AA6B0D1A905E09B58514758C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherRestructuringMember" xlink:label="loc_us-gaap_OtherRestructuringMember_63C5BC2BA1A65CAE299E09B58514C9A1" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfRestructuringDomain_9895618E49E3EB05AF4109B58513EB0C" xlink:to="loc_us-gaap_OtherRestructuringMember_63C5BC2BA1A65CAE299E09B58514C9A1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SegmentReportingInformationLineItems" xlink:label="loc_us-gaap_SegmentReportingInformationLineItems_1E303D8F40D1037C31D509B58514D210" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_514413063999678B0CAB09B585137E1D" xlink:to="loc_us-gaap_SegmentReportingInformationLineItems_1E303D8F40D1037C31D509B58514D210" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_496766B3EF2DD78A041F09B585148E5C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_1E303D8F40D1037C31D509B58514D210" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_496766B3EF2DD78A041F09B585148E5C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_InterestIncomeExpenseNet" xlink:label="loc_us-gaap_InterestIncomeExpenseNet_26834679D07B1F8987BA09B58514CC2D" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_1E303D8F40D1037C31D509B58514D210" xlink:to="loc_us-gaap_InterestIncomeExpenseNet_26834679D07B1F8987BA09B58514CC2D" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_SegmentReportingInformationUnallocatedCorporateExpense" xlink:label="loc_endp_SegmentReportingInformationUnallocatedCorporateExpense_9707C073DAB6470C7FC309B585144DDA" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_1E303D8F40D1037C31D509B58514D210" xlink:to="loc_endp_SegmentReportingInformationUnallocatedCorporateExpense_9707C073DAB6470C7FC309B585144DDA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AmortizationOfIntangibleAssets" xlink:label="loc_us-gaap_AmortizationOfIntangibleAssets_A2566930ED4F01AC07F309B585142D8F" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_1E303D8F40D1037C31D509B58514D210" xlink:to="loc_us-gaap_AmortizationOfIntangibleAssets_A2566930ED4F01AC07F309B585142D8F" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_InventoryStepUp" xlink:label="loc_endp_InventoryStepUp_38A00A8EE8F4E725F16709B5851456D5" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_1E303D8F40D1037C31D509B58514D210" xlink:to="loc_endp_InventoryStepUp_38A00A8EE8F4E725F16709B5851456D5" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_UpfrontAndMilestonePaymentsToPartners" xlink:label="loc_endp_UpfrontAndMilestonePaymentsToPartners_F67A35A539542C3B097009B58514B098" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_1E303D8F40D1037C31D509B58514D210" xlink:to="loc_endp_UpfrontAndMilestonePaymentsToPartners_F67A35A539542C3B097009B58514B098" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_CostReductionInitiatives" xlink:label="loc_endp_CostReductionInitiatives_3D7C827A392E0533BCF709B5851431F5" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_1E303D8F40D1037C31D509B58514D210" xlink:to="loc_endp_CostReductionInitiatives_3D7C827A392E0533BCF709B5851431F5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LossContingencyLossInPeriod" xlink:label="loc_us-gaap_LossContingencyLossInPeriod_3BA5E4F0761C011F0A8209B58514417D" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_1E303D8F40D1037C31D509B58514D210" xlink:to="loc_us-gaap_LossContingencyLossInPeriod_3BA5E4F0761C011F0A8209B58514417D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AssetImpairmentCharges" xlink:label="loc_us-gaap_AssetImpairmentCharges_98AA9CE7207ABD1F47B209B585149125" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_1E303D8F40D1037C31D509B58514D210" xlink:to="loc_us-gaap_AssetImpairmentCharges_98AA9CE7207ABD1F47B209B585149125" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessCombinationAcquisitionRelatedCosts" xlink:label="loc_us-gaap_BusinessCombinationAcquisitionRelatedCosts_BE2E8571A2BE36DBE94609B5851483AE" xlink:type="locator" />
    <link:presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_1E303D8F40D1037C31D509B58514D210" xlink:to="loc_us-gaap_BusinessCombinationAcquisitionRelatedCosts_BE2E8571A2BE36DBE94609B5851483AE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AdjustmentForLongTermIntercompanyTransactionsGrossOfTax" xlink:label="loc_us-gaap_AdjustmentForLongTermIntercompanyTransactionsGrossOfTax_5E47B07502EBBE9976DF09B585143999" xlink:type="locator" />
    <link:presentationArc order="11" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_1E303D8F40D1037C31D509B58514D210" xlink:to="loc_us-gaap_AdjustmentForLongTermIntercompanyTransactionsGrossOfTax_5E47B07502EBBE9976DF09B585143999" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherNonrecurringIncomeExpense" xlink:label="loc_us-gaap_OtherNonrecurringIncomeExpense_95CD905147A17C04D71309B585141975" xlink:type="locator" />
    <link:presentationArc order="12" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_1E303D8F40D1037C31D509B58514D210" xlink:to="loc_us-gaap_OtherNonrecurringIncomeExpense_95CD905147A17C04D71309B585141975" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SeveranceCosts1" xlink:label="loc_us-gaap_SeveranceCosts1_3D194F7F0B4B606F33A609B5851457F7" xlink:type="locator" />
    <link:presentationArc order="13" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_1E303D8F40D1037C31D509B58514D210" xlink:to="loc_us-gaap_SeveranceCosts1_3D194F7F0B4B606F33A609B5851457F7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestructuringReserveAcceleratedDepreciation" xlink:label="loc_us-gaap_RestructuringReserveAcceleratedDepreciation_042870C4F34099ECBDA309B58514057B" xlink:type="locator" />
    <link:presentationArc order="14" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_1E303D8F40D1037C31D509B58514D210" xlink:to="loc_us-gaap_RestructuringReserveAcceleratedDepreciation_042870C4F34099ECBDA309B58514057B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestructuringCharges" xlink:label="loc_us-gaap_RestructuringCharges_10869C2C6958E3F7C8DF09B5851404CC" xlink:type="locator" />
    <link:presentationArc order="15" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_1E303D8F40D1037C31D509B58514D210" xlink:to="loc_us-gaap_RestructuringCharges_10869C2C6958E3F7C8DF09B5851404CC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1_ABAAC8C8DC779A536C6A09B5851476FB" xlink:type="locator" />
    <link:presentationArc order="16" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_1E303D8F40D1037C31D509B58514D210" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1_ABAAC8C8DC779A536C6A09B5851476FB" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_BusinessCombinationClosingTransactionCosts" xlink:label="loc_endp_BusinessCombinationClosingTransactionCosts_9DD5885B489A4E09009F09B585149897" xlink:type="locator" />
    <link:presentationArc order="17" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_1E303D8F40D1037C31D509B58514D210" xlink:to="loc_endp_BusinessCombinationClosingTransactionCosts_9DD5885B489A4E09009F09B585149897" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/SegmentResultsScheduleOfReportableSegmentsInformationDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SegmentReportingAbstract" xlink:label="loc_us-gaap_SegmentReportingAbstract_6338A86B92E79F3973D51D167AB219E1" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable" xlink:label="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_2158D69C6141B3118B561D167AB2E4C5" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingAbstract_6338A86B92E79F3973D51D167AB219E1" xlink:to="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_2158D69C6141B3118B561D167AB2E4C5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_StatementBusinessSegmentsAxis" xlink:label="loc_us-gaap_StatementBusinessSegmentsAxis_239503B15AF0618DB34C1D167AB21E81" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_2158D69C6141B3118B561D167AB2E4C5" xlink:to="loc_us-gaap_StatementBusinessSegmentsAxis_239503B15AF0618DB34C1D167AB21E81" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SegmentDomain" xlink:label="loc_us-gaap_SegmentDomain_F944E24DA2BE70C68AC61D167AB25D6B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_239503B15AF0618DB34C1D167AB21E81" xlink:to="loc_us-gaap_SegmentDomain_F944E24DA2BE70C68AC61D167AB25D6B" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_BrandedSpecialtyandEstablishedPharmaceuticalsMember" xlink:label="loc_endp_BrandedSpecialtyandEstablishedPharmaceuticalsMember_A26F851C3BCE85668D5A1D167AB36DEB" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_F944E24DA2BE70C68AC61D167AB25D6B" xlink:to="loc_endp_BrandedSpecialtyandEstablishedPharmaceuticalsMember_A26F851C3BCE85668D5A1D167AB36DEB" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_BrandedSterileInjectablesMember" xlink:label="loc_endp_BrandedSterileInjectablesMember_304D157436C27BB142391D167AB3A005" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_F944E24DA2BE70C68AC61D167AB25D6B" xlink:to="loc_endp_BrandedSterileInjectablesMember_304D157436C27BB142391D167AB3A005" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_GenericPharmaceuticalsMember" xlink:label="loc_endp_GenericPharmaceuticalsMember_E6416BA4269A7AC2F3C81D167AB35BB7" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_F944E24DA2BE70C68AC61D167AB25D6B" xlink:to="loc_endp_GenericPharmaceuticalsMember_E6416BA4269A7AC2F3C81D167AB35BB7" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_InternationalPharmaceuticalsMember" xlink:label="loc_endp_InternationalPharmaceuticalsMember_7A7DD552C00E20A84B551D167AB389EE" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_F944E24DA2BE70C68AC61D167AB25D6B" xlink:to="loc_endp_InternationalPharmaceuticalsMember_7A7DD552C00E20A84B551D167AB389EE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SegmentReportingInformationLineItems" xlink:label="loc_us-gaap_SegmentReportingInformationLineItems_DC78204FF24F1C850A1A1D167AB33869" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_2158D69C6141B3118B561D167AB2E4C5" xlink:to="loc_us-gaap_SegmentReportingInformationLineItems_DC78204FF24F1C850A1A1D167AB33869" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_NumberOfReportableSegments" xlink:label="loc_us-gaap_NumberOfReportableSegments_C78777B12D59A828E7DC1D167AB31030" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_DC78204FF24F1C850A1A1D167AB33869" xlink:to="loc_us-gaap_NumberOfReportableSegments_C78777B12D59A828E7DC1D167AB31030" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_Revenues" xlink:label="loc_us-gaap_Revenues_C95BC1C63B177F6CDF0A1D167AB30B0B" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/netLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_DC78204FF24F1C850A1A1D167AB33869" xlink:to="loc_us-gaap_Revenues_C95BC1C63B177F6CDF0A1D167AB30B0B" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_AdjustedIncomeLossBeforeIncomeTax" xlink:label="loc_endp_AdjustedIncomeLossBeforeIncomeTax_B279F8935BE3CDA9C0B61D167AB317E6" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_DC78204FF24F1C850A1A1D167AB33869" xlink:to="loc_endp_AdjustedIncomeLossBeforeIncomeTax_B279F8935BE3CDA9C0B61D167AB317E6" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/SegmentResultsTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SegmentReportingAbstract" xlink:label="loc_us-gaap_SegmentReportingAbstract_DDF923132415E73C1E11F37530DDE5C5" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScheduleOfSegmentReportingInformationBySegmentTextBlock" xlink:label="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTextBlock_99AB8A8434511D5A56C8F37530DDE50D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingAbstract_DDF923132415E73C1E11F37530DDE5C5" xlink:to="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTextBlock_99AB8A8434511D5A56C8F37530DDE50D" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_ScheduleOfReconciliationsOfConsolidatedAdjustedIncomeLossBeforeIncomeTaxToConsolidatedIncomeBeforeIncomeTaxTableTextBlock" xlink:label="loc_endp_ScheduleOfReconciliationsOfConsolidatedAdjustedIncomeLossBeforeIncomeTaxToConsolidatedIncomeBeforeIncomeTaxTableTextBlock_2D6008F5D8570F8A1432F37530DD3D7A" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingAbstract_DDF923132415E73C1E11F37530DDE5C5" xlink:to="loc_endp_ScheduleOfReconciliationsOfConsolidatedAdjustedIncomeLossBeforeIncomeTaxToConsolidatedIncomeBeforeIncomeTaxTableTextBlock_2D6008F5D8570F8A1432F37530DD3D7A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DisaggregationOfRevenueTableTextBlock" xlink:label="loc_us-gaap_DisaggregationOfRevenueTableTextBlock_F463BC2617400039DDE8F3A13E67ED66" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingAbstract_DDF923132415E73C1E11F37530DDE5C5" xlink:to="loc_us-gaap_DisaggregationOfRevenueTableTextBlock_F463BC2617400039DDE8F3A13E67ED66" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/ShareholdersDeficitEquityDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_EquityAbstract" xlink:label="loc_us-gaap_EquityAbstract_A94ACE82B403BFF2A5222C6E35FD7E1F" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_3D4FC7C8C0C712F6E11E2C6E35FDC83C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_A94ACE82B403BFF2A5222C6E35FD7E1F" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_3D4FC7C8C0C712F6E11E2C6E35FDC83C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SubsequentEventTypeAxis" xlink:label="loc_us-gaap_SubsequentEventTypeAxis_D44BE93514C966109DF92C6E35FD82C5" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_3D4FC7C8C0C712F6E11E2C6E35FDC83C" xlink:to="loc_us-gaap_SubsequentEventTypeAxis_D44BE93514C966109DF92C6E35FD82C5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SubsequentEventTypeDomain" xlink:label="loc_us-gaap_SubsequentEventTypeDomain_AE73E8DC14AB5D31C1B42C6E35FD4053" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTypeAxis_D44BE93514C966109DF92C6E35FD82C5" xlink:to="loc_us-gaap_SubsequentEventTypeDomain_AE73E8DC14AB5D31C1B42C6E35FD4053" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SubsequentEventMember" xlink:label="loc_us-gaap_SubsequentEventMember_9888CC5F78BAAC46E53D2C6E35FD12E3" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTypeDomain_AE73E8DC14AB5D31C1B42C6E35FD4053" xlink:to="loc_us-gaap_SubsequentEventMember_9888CC5F78BAAC46E53D2C6E35FD12E3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AwardTypeAxis" xlink:label="loc_us-gaap_AwardTypeAxis_A3CA673AA14CA0185D362C6E35FD9FB8" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_3D4FC7C8C0C712F6E11E2C6E35FDC83C" xlink:to="loc_us-gaap_AwardTypeAxis_A3CA673AA14CA0185D362C6E35FD9FB8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_C644774D0E035093E8392C6E35FDEEAF" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_A3CA673AA14CA0185D362C6E35FD9FB8" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_C644774D0E035093E8392C6E35FDEEAF" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_NonVestedRestrictedStockMember" xlink:label="loc_endp_NonVestedRestrictedStockMember_A67A8FD36DC06D78BA3F2C6E35FD3337" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_C644774D0E035093E8392C6E35FDEEAF" xlink:to="loc_endp_NonVestedRestrictedStockMember_A67A8FD36DC06D78BA3F2C6E35FD3337" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_PerformanceStockUnitsMember" xlink:label="loc_endp_PerformanceStockUnitsMember_B34C109F6C56A4F85E022C6E35FDA6E2" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_C644774D0E035093E8392C6E35FDEEAF" xlink:to="loc_endp_PerformanceStockUnitsMember_B34C109F6C56A4F85E022C6E35FDA6E2" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_NonVestedStockOptionsMember" xlink:label="loc_endp_NonVestedStockOptionsMember_735BAF61E3996E5AF2B02C6E35FD143D" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_C644774D0E035093E8392C6E35FDEEAF" xlink:to="loc_endp_NonVestedStockOptionsMember_735BAF61E3996E5AF2B02C6E35FD143D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_StatementScenarioAxis" xlink:label="loc_us-gaap_StatementScenarioAxis_BDE7D6ABBE55E8094BBC2C6E35FDA863" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_3D4FC7C8C0C712F6E11E2C6E35FDC83C" xlink:to="loc_us-gaap_StatementScenarioAxis_BDE7D6ABBE55E8094BBC2C6E35FDA863" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScenarioUnspecifiedDomain" xlink:label="loc_us-gaap_ScenarioUnspecifiedDomain_B42834AA76BB57B020CF2C6E35FD4818" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementScenarioAxis_BDE7D6ABBE55E8094BBC2C6E35FDA863" xlink:to="loc_us-gaap_ScenarioUnspecifiedDomain_B42834AA76BB57B020CF2C6E35FD4818" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScenarioPlanMember" xlink:label="loc_us-gaap_ScenarioPlanMember_353244400D568D4BF61D2C6E35FDB3F8" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScenarioUnspecifiedDomain_B42834AA76BB57B020CF2C6E35FD4818" xlink:to="loc_us-gaap_ScenarioPlanMember_353244400D568D4BF61D2C6E35FDB3F8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_AAC1F88822E065F351F12C6E35FDF6E3" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_3D4FC7C8C0C712F6E11E2C6E35FDC83C" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_AAC1F88822E065F351F12C6E35FDF6E3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ShareBasedCompensation" xlink:label="loc_us-gaap_ShareBasedCompensation_2670EF97910F483238152C6E35FD2DA1" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_AAC1F88822E065F351F12C6E35FDF6E3" xlink:to="loc_us-gaap_ShareBasedCompensation_2670EF97910F483238152C6E35FD2DA1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognized" xlink:label="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognized_84586C7E6BFF98FE85812C6E35FE66A2" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_AAC1F88822E065F351F12C6E35FDF6E3" xlink:to="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognized_84586C7E6BFF98FE85812C6E35FE66A2" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_SharebasedCompensationArrangementbySharebasedPaymentAwardOptionsAwardedinPeriodNotYetGrantedGross" xlink:label="loc_endp_SharebasedCompensationArrangementbySharebasedPaymentAwardOptionsAwardedinPeriodNotYetGrantedGross_C0CD434FE8E7DBDE06C82D5731BE06D4" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2009/role/netLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_AAC1F88822E065F351F12C6E35FDF6E3" xlink:to="loc_endp_SharebasedCompensationArrangementbySharebasedPaymentAwardOptionsAwardedinPeriodNotYetGrantedGross_C0CD434FE8E7DBDE06C82D5731BE06D4" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_SharebasedCompensationArrangementbySharebasedPaymentAwardEquityInstrumentsOtherthanOptionsAwardedinPeriodNotYetGranted" xlink:label="loc_endp_SharebasedCompensationArrangementbySharebasedPaymentAwardEquityInstrumentsOtherthanOptionsAwardedinPeriodNotYetGranted_98BC7C90992EC8FFE7172D58E1E24FFC" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_AAC1F88822E065F351F12C6E35FDF6E3" xlink:to="loc_endp_SharebasedCompensationArrangementbySharebasedPaymentAwardEquityInstrumentsOtherthanOptionsAwardedinPeriodNotYetGranted_98BC7C90992EC8FFE7172D58E1E24FFC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_2B4359289ADF39FD7FC02C6E35FED918" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_AAC1F88822E065F351F12C6E35FDF6E3" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_2B4359289ADF39FD7FC02C6E35FED918" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedPeriodForRecognition1" xlink:label="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedPeriodForRecognition1_85D2B370C28A48FCA6322C6E35FE4F18" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_AAC1F88822E065F351F12C6E35FDF6E3" xlink:to="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedPeriodForRecognition1_85D2B370C28A48FCA6322C6E35FE4F18" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/ShareholdersDeficitEquityScheduleOfChangesInShareholdersEquityDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_EquityAbstract" xlink:label="loc_us-gaap_EquityAbstract_F3CAA659AB8E060F4B9B3C57101A2808" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncreaseDecreaseInStockholdersEquityRollForward" xlink:label="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_0A426918378E898E686A3C57101AF48F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_F3CAA659AB8E060F4B9B3C57101A2808" xlink:to="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_0A426918378E898E686A3C57101AF48F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest" xlink:label="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest_8C3A9005AB0E52943FC13C57101AD13C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_0A426918378E898E686A3C57101AF48F" xlink:to="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest_8C3A9005AB0E52943FC13C57101AD13C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CumulativeEffectOfNewAccountingPrincipleInPeriodOfAdoption" xlink:label="loc_us-gaap_CumulativeEffectOfNewAccountingPrincipleInPeriodOfAdoption_0D71798B9A8735C23B2C3C57101A2117" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/netLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_0A426918378E898E686A3C57101AF48F" xlink:to="loc_us-gaap_CumulativeEffectOfNewAccountingPrincipleInPeriodOfAdoption_0D71798B9A8735C23B2C3C57101A2117" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterestAdjustedBalance1" xlink:label="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterestAdjustedBalance1_62A768128593A0B91C273C57101ADB4C" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_0A426918378E898E686A3C57101AF48F" xlink:to="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterestAdjustedBalance1_62A768128593A0B91C273C57101ADB4C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ProfitLoss" xlink:label="loc_us-gaap_ProfitLoss_F75E3CE45C4E5C598DD23C57101A48CF" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_0A426918378E898E686A3C57101AF48F" xlink:to="loc_us-gaap_ProfitLoss_F75E3CE45C4E5C598DD23C57101A48CF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTax" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax_A85F99BF0D999DBBC6B33C57101A448A" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_0A426918378E898E686A3C57101AF48F" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax_A85F99BF0D999DBBC6B33C57101A448A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue" xlink:label="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue_EC8AF19590D8C75FADDE3C57101A3E38" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_0A426918378E898E686A3C57101AF48F" xlink:to="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue_EC8AF19590D8C75FADDE3C57101A3E38" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AdjustmentsRelatedToTaxWithholdingForShareBasedCompensation" xlink:label="loc_us-gaap_AdjustmentsRelatedToTaxWithholdingForShareBasedCompensation_DB212D6A65E0125C67DA3C57101A6580" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_0A426918378E898E686A3C57101AF48F" xlink:to="loc_us-gaap_AdjustmentsRelatedToTaxWithholdingForShareBasedCompensation_DB212D6A65E0125C67DA3C57101A6580" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_StockholdersEquityOther" xlink:label="loc_us-gaap_StockholdersEquityOther_CCF3E74F75DF0CCD24133C57101AB566" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_0A426918378E898E686A3C57101AF48F" xlink:to="loc_us-gaap_StockholdersEquityOther_CCF3E74F75DF0CCD24133C57101AB566" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest" xlink:label="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest_5670A8BE8EF06232FC003C57101ADB0C" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_0A426918378E898E686A3C57101AF48F" xlink:to="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest_5670A8BE8EF06232FC003C57101ADB0C" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/ShareholdersDeficitEquityShareholdersDeficitEquity" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_EquityAbstract" xlink:label="loc_us-gaap_EquityAbstract_4307F0CB2E823B57A537F8D3FA4089D0" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_StockholdersEquityNoteDisclosureTextBlock" xlink:label="loc_us-gaap_StockholdersEquityNoteDisclosureTextBlock_28AA4299F5B57467D439F8D3FA40B33E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_4307F0CB2E823B57A537F8D3FA4089D0" xlink:to="loc_us-gaap_StockholdersEquityNoteDisclosureTextBlock_28AA4299F5B57467D439F8D3FA40B33E" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/ShareholdersDeficitEquityTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_EquityAbstract" xlink:label="loc_us-gaap_EquityAbstract_E428F8B2DB2F70DA82B3F5AA462B952E" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScheduleOfStockholdersEquityTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfStockholdersEquityTableTextBlock_6421E1FA063F329CC6EBF5AF05E9AA8F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_E428F8B2DB2F70DA82B3F5AA462B952E" xlink:to="loc_us-gaap_ScheduleOfStockholdersEquityTableTextBlock_6421E1FA063F329CC6EBF5AF05E9AA8F" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/SubsequentEvents" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SubsequentEventsAbstract" xlink:label="loc_us-gaap_SubsequentEventsAbstract_5BFD3FC131E48ADABE7016A11D8DCEA3" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SubsequentEventsPolicyPolicyTextBlock" xlink:label="loc_us-gaap_SubsequentEventsPolicyPolicyTextBlock_249DF786BE151DD5E09316A11D8D4B91" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventsAbstract_5BFD3FC131E48ADABE7016A11D8DCEA3" xlink:to="loc_us-gaap_SubsequentEventsPolicyPolicyTextBlock_249DF786BE151DD5E09316A11D8D4B91" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/SubsequentEventsDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SubsequentEventsAbstract" xlink:label="loc_us-gaap_SubsequentEventsAbstract_A45AB9E7CFD997EA53AFF99E39BC8AD7" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SubsequentEventTable" xlink:label="loc_us-gaap_SubsequentEventTable_714DCCF04BC2AC9BEC39F99E39BC2BA0" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventsAbstract_A45AB9E7CFD997EA53AFF99E39BC8AD7" xlink:to="loc_us-gaap_SubsequentEventTable_714DCCF04BC2AC9BEC39F99E39BC2BA0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_StatementScenarioAxis" xlink:label="loc_us-gaap_StatementScenarioAxis_87398DEB6C6D2763C96BF9A8181B19CF" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTable_714DCCF04BC2AC9BEC39F99E39BC2BA0" xlink:to="loc_us-gaap_StatementScenarioAxis_87398DEB6C6D2763C96BF9A8181B19CF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScenarioUnspecifiedDomain" xlink:label="loc_us-gaap_ScenarioUnspecifiedDomain_1A98DB7A40841AEDAB93F9A8181BC576" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementScenarioAxis_87398DEB6C6D2763C96BF9A8181B19CF" xlink:to="loc_us-gaap_ScenarioUnspecifiedDomain_1A98DB7A40841AEDAB93F9A8181BC576" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScenarioForecastMember" xlink:label="loc_us-gaap_ScenarioForecastMember_85B5B3442FF6576EF2E5F9A84CBFFA3E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScenarioUnspecifiedDomain_1A98DB7A40841AEDAB93F9A8181BC576" xlink:to="loc_us-gaap_ScenarioForecastMember_85B5B3442FF6576EF2E5F9A84CBFFA3E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessAcquisitionAxis" xlink:label="loc_us-gaap_BusinessAcquisitionAxis_0FF9E1A75C6916AB43E1F9A3ECB94A4F" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTable_714DCCF04BC2AC9BEC39F99E39BC2BA0" xlink:to="loc_us-gaap_BusinessAcquisitionAxis_0FF9E1A75C6916AB43E1F9A3ECB94A4F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_63AA9D83649D5F7A9DE9F9A3ECB94009" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_0FF9E1A75C6916AB43E1F9A3ECB94A4F" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_63AA9D83649D5F7A9DE9F9A3ECB94009" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_SomersetTherapeuticsLLCMember" xlink:label="loc_endp_SomersetTherapeuticsLLCMember_27B267E843B7DF3189A9F9A4695950BE" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_63AA9D83649D5F7A9DE9F9A3ECB94009" xlink:to="loc_endp_SomersetTherapeuticsLLCMember_27B267E843B7DF3189A9F9A4695950BE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SubsequentEventLineItems" xlink:label="loc_us-gaap_SubsequentEventLineItems_46C477F0545FAEFED5BEF99E39BD1894" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTable_714DCCF04BC2AC9BEC39F99E39BC2BA0" xlink:to="loc_us-gaap_SubsequentEventLineItems_46C477F0545FAEFED5BEF99E39BD1894" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessAcquisitionPercentageOfVotingInterestsAcquired" xlink:label="loc_us-gaap_BusinessAcquisitionPercentageOfVotingInterestsAcquired_FFE03D9DB8D290B245FFF9A362E1059F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventLineItems_46C477F0545FAEFED5BEF99E39BD1894" xlink:to="loc_us-gaap_BusinessAcquisitionPercentageOfVotingInterestsAcquired_FFE03D9DB8D290B245FFF9A362E1059F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessCombinationConsiderationTransferred1" xlink:label="loc_us-gaap_BusinessCombinationConsiderationTransferred1_A82CA225456B6753AA48F9AA465487FF" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/netLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventLineItems_46C477F0545FAEFED5BEF99E39BD1894" xlink:to="loc_us-gaap_BusinessCombinationConsiderationTransferred1_A82CA225456B6753AA48F9AA465487FF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNoncurrentLiabilitiesLongTermDebt" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNoncurrentLiabilitiesLongTermDebt_5A5988798580B6A82A0FF9AB583D631E" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventLineItems_46C477F0545FAEFED5BEF99E39BD1894" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNoncurrentLiabilitiesLongTermDebt_5A5988798580B6A82A0FF9AB583D631E" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/SummaryOfSignificantAccountingPolicies" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccountingPoliciesAbstract" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_452EC86CBBF5DC5EEF5EF9E7F85FA725" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SignificantAccountingPoliciesTextBlock" xlink:label="loc_us-gaap_SignificantAccountingPoliciesTextBlock_304E1C3A4689A0626A17F9E7F85F5A1F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_452EC86CBBF5DC5EEF5EF9E7F85FA725" xlink:to="loc_us-gaap_SignificantAccountingPoliciesTextBlock_304E1C3A4689A0626A17F9E7F85F5A1F" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/SummaryOfSignificantAccountingPoliciesPolicies" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccountingPoliciesAbstract" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_7D6A4065747C3469552BF9E7F85E44CB" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RevenueRecognitionPolicyTextBlock" xlink:label="loc_us-gaap_RevenueRecognitionPolicyTextBlock_609FE26608A70675FF93F9E7F85E211A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_7D6A4065747C3469552BF9E7F85E44CB" xlink:to="loc_us-gaap_RevenueRecognitionPolicyTextBlock_609FE26608A70675FF93F9E7F85E211A" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_RecentAccountingPronouncementsPolicyTextBlock" xlink:label="loc_endp_RecentAccountingPronouncementsPolicyTextBlock_21EAA33A58B76FFDC542F9E7F85EEBFA" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_7D6A4065747C3469552BF9E7F85E44CB" xlink:to="loc_endp_RecentAccountingPronouncementsPolicyTextBlock_21EAA33A58B76FFDC542F9E7F85EEBFA" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/SummaryOfSignificantAccountingPoliciesScheduleOfImpactOfAsc606Details" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccountingPoliciesAbstract" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_D1C58597BBFE095CAA1D3C343E8B1E28" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RevenueInitialApplicationPeriodCumulativeEffectTransitionTable" xlink:label="loc_us-gaap_RevenueInitialApplicationPeriodCumulativeEffectTransitionTable_45C487FD863AA0D32CD43C343E8B65B6" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_D1C58597BBFE095CAA1D3C343E8B1E28" xlink:to="loc_us-gaap_RevenueInitialApplicationPeriodCumulativeEffectTransitionTable_45C487FD863AA0D32CD43C343E8B65B6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_StatementEquityComponentsAxis" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_272D375815F12F6D5C483C343E8BDFDF" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RevenueInitialApplicationPeriodCumulativeEffectTransitionTable_45C487FD863AA0D32CD43C343E8B65B6" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_272D375815F12F6D5C483C343E8BDFDF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_EquityComponentDomain" xlink:label="loc_us-gaap_EquityComponentDomain_7830B8BB7E728BEBD5853C343E8CE127" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_272D375815F12F6D5C483C343E8BDFDF" xlink:to="loc_us-gaap_EquityComponentDomain_7830B8BB7E728BEBD5853C343E8CE127" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RetainedEarningsMember" xlink:label="loc_us-gaap_RetainedEarningsMember_D2FC4F02C9BDA29E689D3C343E8CA6CA" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_7830B8BB7E728BEBD5853C343E8CE127" xlink:to="loc_us-gaap_RetainedEarningsMember_D2FC4F02C9BDA29E689D3C343E8CA6CA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_InitialApplicationPeriodCumulativeEffectTransitionAxis" xlink:label="loc_us-gaap_InitialApplicationPeriodCumulativeEffectTransitionAxis_D198EC1396BD7C3A63303C343E8D3A27" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RevenueInitialApplicationPeriodCumulativeEffectTransitionTable_45C487FD863AA0D32CD43C343E8B65B6" xlink:to="loc_us-gaap_InitialApplicationPeriodCumulativeEffectTransitionAxis_D198EC1396BD7C3A63303C343E8D3A27" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_InitialApplicationPeriodCumulativeEffectTransitionDomain" xlink:label="loc_us-gaap_InitialApplicationPeriodCumulativeEffectTransitionDomain_734CFDFF3E80492EA2BE3C343E8D25FC" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InitialApplicationPeriodCumulativeEffectTransitionAxis_D198EC1396BD7C3A63303C343E8D3A27" xlink:to="loc_us-gaap_InitialApplicationPeriodCumulativeEffectTransitionDomain_734CFDFF3E80492EA2BE3C343E8D25FC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CalculatedUnderRevenueGuidanceInEffectBeforeTopic606Member" xlink:label="loc_us-gaap_CalculatedUnderRevenueGuidanceInEffectBeforeTopic606Member_66F5000BA4DB9267D8C53C343E8E71E4" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InitialApplicationPeriodCumulativeEffectTransitionDomain_734CFDFF3E80492EA2BE3C343E8D25FC" xlink:to="loc_us-gaap_CalculatedUnderRevenueGuidanceInEffectBeforeTopic606Member_66F5000BA4DB9267D8C53C343E8E71E4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DifferenceBetweenRevenueGuidanceInEffectBeforeAndAfterTopic606Member" xlink:label="loc_us-gaap_DifferenceBetweenRevenueGuidanceInEffectBeforeAndAfterTopic606Member_5F5BC3AAED11575E090B3C343E8E63EF" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InitialApplicationPeriodCumulativeEffectTransitionDomain_734CFDFF3E80492EA2BE3C343E8D25FC" xlink:to="loc_us-gaap_DifferenceBetweenRevenueGuidanceInEffectBeforeAndAfterTopic606Member_5F5BC3AAED11575E090B3C343E8E63EF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AdjustmentsForNewAccountingPronouncementsAxis" xlink:label="loc_us-gaap_AdjustmentsForNewAccountingPronouncementsAxis_274E50B7C2477C44482F3C343E8F8284" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RevenueInitialApplicationPeriodCumulativeEffectTransitionTable_45C487FD863AA0D32CD43C343E8B65B6" xlink:to="loc_us-gaap_AdjustmentsForNewAccountingPronouncementsAxis_274E50B7C2477C44482F3C343E8F8284" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_TypeOfAdoptionMember" xlink:label="loc_us-gaap_TypeOfAdoptionMember_679EB38460B059917B903C343E8F0E8F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsForNewAccountingPronouncementsAxis_274E50B7C2477C44482F3C343E8F8284" xlink:to="loc_us-gaap_TypeOfAdoptionMember_679EB38460B059917B903C343E8F0E8F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccountingStandardsUpdate201409Member" xlink:label="loc_us-gaap_AccountingStandardsUpdate201409Member_AC399050F554469198223C343E8FB2A1" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfAdoptionMember_679EB38460B059917B903C343E8F0E8F" xlink:to="loc_us-gaap_AccountingStandardsUpdate201409Member_AC399050F554469198223C343E8FB2A1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RevenueInitialApplicationPeriodCumulativeEffectTransitionLineItems" xlink:label="loc_us-gaap_RevenueInitialApplicationPeriodCumulativeEffectTransitionLineItems_4346015112DEE1B52E0D3C343E8FD58D" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RevenueInitialApplicationPeriodCumulativeEffectTransitionTable_45C487FD863AA0D32CD43C343E8B65B6" xlink:to="loc_us-gaap_RevenueInitialApplicationPeriodCumulativeEffectTransitionLineItems_4346015112DEE1B52E0D3C343E8FD58D" xlink:type="arc" />
    <link:loc xlink:href="endp-20180331.xsd#endp_DiscountOnBrandNameDrugs" xlink:label="loc_endp_DiscountOnBrandNameDrugs_4B1597140A83DFC9D2AE3C343E8FA51D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RevenueInitialApplicationPeriodCumulativeEffectTransitionLineItems_4346015112DEE1B52E0D3C343E8FD58D" xlink:to="loc_endp_DiscountOnBrandNameDrugs_4B1597140A83DFC9D2AE3C343E8FA51D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CumulativeEffectOfNewAccountingPrincipleInPeriodOfAdoption" xlink:label="loc_us-gaap_CumulativeEffectOfNewAccountingPrincipleInPeriodOfAdoption_E957340F874E2E768A8F3C343E90444D" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RevenueInitialApplicationPeriodCumulativeEffectTransitionLineItems_4346015112DEE1B52E0D3C343E8FD58D" xlink:to="loc_us-gaap_CumulativeEffectOfNewAccountingPrincipleInPeriodOfAdoption_E957340F874E2E768A8F3C343E90444D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeStatementAbstract" xlink:label="loc_us-gaap_IncomeStatementAbstract_D1EA0A66EC4757F4DD6B3C343E90B0F3" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RevenueInitialApplicationPeriodCumulativeEffectTransitionLineItems_4346015112DEE1B52E0D3C343E8FD58D" xlink:to="loc_us-gaap_IncomeStatementAbstract_D1EA0A66EC4757F4DD6B3C343E90B0F3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_Revenues" xlink:label="loc_us-gaap_Revenues_7B5709EDEBFE5823C9C43C343E90F103" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_D1EA0A66EC4757F4DD6B3C343E90B0F3" xlink:to="loc_us-gaap_Revenues_7B5709EDEBFE5823C9C43C343E90F103" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CostOfRevenue" xlink:label="loc_us-gaap_CostOfRevenue_F487B11C31CF05AB02BD3C343E9112FF" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_D1EA0A66EC4757F4DD6B3C343E90B0F3" xlink:to="loc_us-gaap_CostOfRevenue_F487B11C31CF05AB02BD3C343E9112FF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsIncludingPortionAttributableToNoncontrollingInterest" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsIncludingPortionAttributableToNoncontrollingInterest_8FEABFBFB714589E36283C343E92A375" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_D1EA0A66EC4757F4DD6B3C343E90B0F3" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsIncludingPortionAttributableToNoncontrollingInterest_8FEABFBFB714589E36283C343E92A375" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_NetIncomeLoss" xlink:label="loc_us-gaap_NetIncomeLoss_C9185DA428155AF3BE573C343E92EE7A" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2009/role/netLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_D1EA0A66EC4757F4DD6B3C343E90B0F3" xlink:to="loc_us-gaap_NetIncomeLoss_C9185DA428155AF3BE573C343E92EE7A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_EarningsPerShareBasicAbstract" xlink:label="loc_us-gaap_EarningsPerShareBasicAbstract_D50B41271FA9625DC7143C343E9293E1" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_D1EA0A66EC4757F4DD6B3C343E90B0F3" xlink:to="loc_us-gaap_EarningsPerShareBasicAbstract_D50B41271FA9625DC7143C343E9293E1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsPerBasicShare" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsPerBasicShare_41D8DDE91BC104B817213C343E92EA24" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareBasicAbstract_D50B41271FA9625DC7143C343E9293E1" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsPerBasicShare_41D8DDE91BC104B817213C343E92EA24" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_EarningsPerShareBasic" xlink:label="loc_us-gaap_EarningsPerShareBasic_C18FF349C3F3515EBDAC3C343E93FCC2" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareBasicAbstract_D50B41271FA9625DC7143C343E9293E1" xlink:to="loc_us-gaap_EarningsPerShareBasic_C18FF349C3F3515EBDAC3C343E93FCC2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_EarningsPerShareDilutedAbstract" xlink:label="loc_us-gaap_EarningsPerShareDilutedAbstract_905FDAA7B0FB91F637AC3C343E9318CF" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_D1EA0A66EC4757F4DD6B3C343E90B0F3" xlink:to="loc_us-gaap_EarningsPerShareDilutedAbstract_905FDAA7B0FB91F637AC3C343E9318CF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsPerDilutedShare" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsPerDilutedShare_5D5D4296DE3EEB49AA583C343E9305C0" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareDilutedAbstract_905FDAA7B0FB91F637AC3C343E9318CF" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsPerDilutedShare_5D5D4296DE3EEB49AA583C343E9305C0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_EarningsPerShareDiluted" xlink:label="loc_us-gaap_EarningsPerShareDiluted_EE24C83C0366DC3E3FF83C343E93385B" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareDilutedAbstract_905FDAA7B0FB91F637AC3C343E9318CF" xlink:to="loc_us-gaap_EarningsPerShareDiluted_EE24C83C0366DC3E3FF83C343E93385B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_StatementOfFinancialPositionAbstract" xlink:label="loc_us-gaap_StatementOfFinancialPositionAbstract_F99A06A3D510ED5CD11D3C343E9365C5" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RevenueInitialApplicationPeriodCumulativeEffectTransitionLineItems_4346015112DEE1B52E0D3C343E8FD58D" xlink:to="loc_us-gaap_StatementOfFinancialPositionAbstract_F99A06A3D510ED5CD11D3C343E9365C5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AssetsAbstract" xlink:label="loc_us-gaap_AssetsAbstract_CEF38922C9AC6268A4883C343E9485C0" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_F99A06A3D510ED5CD11D3C343E9365C5" xlink:to="loc_us-gaap_AssetsAbstract_CEF38922C9AC6268A4883C343E9485C0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_InventoryNet" xlink:label="loc_us-gaap_InventoryNet_B229967F03E1EA11B6FC3C343E94C3BB" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_CEF38922C9AC6268A4883C343E9485C0" xlink:to="loc_us-gaap_InventoryNet_B229967F03E1EA11B6FC3C343E94C3BB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_PrepaidExpenseAndOtherAssetsCurrent" xlink:label="loc_us-gaap_PrepaidExpenseAndOtherAssetsCurrent_DEEC467C9C66FAF39B1F3C343E942943" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_CEF38922C9AC6268A4883C343E9485C0" xlink:to="loc_us-gaap_PrepaidExpenseAndOtherAssetsCurrent_DEEC467C9C66FAF39B1F3C343E942943" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherAssetsNoncurrent" xlink:label="loc_us-gaap_OtherAssetsNoncurrent_64D6359092625339AD4A3C343E94EB72" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_CEF38922C9AC6268A4883C343E9485C0" xlink:to="loc_us-gaap_OtherAssetsNoncurrent_64D6359092625339AD4A3C343E94EB72" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LiabilitiesAbstract" xlink:label="loc_us-gaap_LiabilitiesAbstract_07F94000E10B08176E303C343E94B6D5" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_F99A06A3D510ED5CD11D3C343E9365C5" xlink:to="loc_us-gaap_LiabilitiesAbstract_07F94000E10B08176E303C343E94B6D5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccountsPayableAndAccruedLiabilitiesCurrent" xlink:label="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesCurrent_35ADD09DA1EC49AAC1333C343E9446C4" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAbstract_07F94000E10B08176E303C343E94B6D5" xlink:to="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesCurrent_35ADD09DA1EC49AAC1333C343E9446C4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_StatementOfStockholdersEquityAbstract" xlink:label="loc_us-gaap_StatementOfStockholdersEquityAbstract_2CA5921E267A782407593C343E9502DE" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_F99A06A3D510ED5CD11D3C343E9365C5" xlink:to="loc_us-gaap_StatementOfStockholdersEquityAbstract_2CA5921E267A782407593C343E9502DE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RetainedEarningsAccumulatedDeficit" xlink:label="loc_us-gaap_RetainedEarningsAccumulatedDeficit_58E7C4927A28CBF8BA193C343E95B468" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfStockholdersEquityAbstract_2CA5921E267A782407593C343E9502DE" xlink:to="loc_us-gaap_RetainedEarningsAccumulatedDeficit_58E7C4927A28CBF8BA193C343E95B468" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.endo.com/role/SummaryOfSignificantAccountingPoliciesTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccountingPoliciesAbstract" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_AA3267A8A1AEC21D8852080947F3E382" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScheduleOfNewAccountingPronouncementsAndChangesInAccountingPrinciplesTextBlock" xlink:label="loc_us-gaap_ScheduleOfNewAccountingPronouncementsAndChangesInAccountingPrinciplesTextBlock_5E023698FE2A9FB73ED7080947F3BACF" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_AA3267A8A1AEC21D8852080947F3E382" xlink:to="loc_us-gaap_ScheduleOfNewAccountingPronouncementsAndChangesInAccountingPrinciplesTextBlock_5E023698FE2A9FB73ED7080947F3BACF" xlink:type="arc" />
  </link:presentationLink>
</link:linkbase>