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    <link:loc xlink:href="endp-20200331.xsd#endp_FivePointSevenFiveSeniorNotesDueOnTwoThousandTwentyTwoMember" xlink:label="loc_endp_FivePointSevenFiveSeniorNotesDueOnTwoThousandTwentyTwoMember_F1F4D44C825C57D1801C820F01B123C4" xlink:type="locator" />
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    <link:label id="lab_endp_FivePointThreeSevenFiveSeniorNotesDueOnTwoThousandTwentyThreeMember_85CFE6B717AF178C6CE11530AB6EA7BD_terseLabel_en-US" xlink:label="lab_endp_FivePointThreeSevenFiveSeniorNotesDueOnTwoThousandTwentyThreeMember_0DD72F6D227952D5BFF06054466DD810" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">5.375% Senior Notes due 2023</link:label>
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    <link:label id="lab_endp_FivePointThreeSevenFiveSeniorNotesDueOnTwoThousandTwentyThreeMember_85CFE6B717AF178C6CE11530AB6EA7BD_documentation_en-US" xlink:label="lab_endp_FivePointThreeSevenFiveSeniorNotesDueOnTwoThousandTwentyThreeMember_0DD72F6D227952D5BFF06054466DD810" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Five Point Three Seven Five Senior Notes Due On Two Thousand Twenty Three [Member]</link:label>
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    <link:label id="lab_endp_SixPointZeroPercentSeniorNotesDueTwoThousandTwentyThreeMember_A63426B93129AE1C35E41530AB6E2ECD_documentation_en-US" xlink:label="lab_endp_SixPointZeroPercentSeniorNotesDueTwoThousandTwentyThreeMember_2F4C1A2A902E512295B07CA9768921DA" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Six Point Zero Percent Senior Notes Due Two Thousand Twenty Three [Member]</link:label>
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    <link:label id="lab_endp_AccruedLiabilitiesReturnsAndAllowances_3330433F54E60AFD0BBB69023BC5E4EF_documentation_en-US" xlink:label="lab_endp_AccruedLiabilitiesReturnsAndAllowances_3FD10752D5A25AF3B607DE757BB7AEAC" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Accrued liabilities returns and allowances.</link:label>
    <link:loc xlink:href="endp-20200331.xsd#endp_AccruedLiabilitiesReturnsAndAllowances" xlink:label="loc_endp_AccruedLiabilitiesReturnsAndAllowances_3FD10752D5A25AF3B607DE757BB7AEAC" xlink:type="locator" />
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    <link:label id="lab_endp_AccruedLiabilitiesRebates_3FF3FDC63D4FB062418D69023BC53750_label_en-US" xlink:label="lab_endp_AccruedLiabilitiesRebates_25062B231706589B8566C8E59E11A65F" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Accrued Liabilities, Rebates</link:label>
    <link:label id="lab_endp_AccruedLiabilitiesRebates_3FF3FDC63D4FB062418D69023BC53750_documentation_en-US" xlink:label="lab_endp_AccruedLiabilitiesRebates_25062B231706589B8566C8E59E11A65F" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Accrued Liabilities, Rebates</link:label>
    <link:loc xlink:href="endp-20200331.xsd#endp_AccruedLiabilitiesRebates" xlink:label="loc_endp_AccruedLiabilitiesRebates_25062B231706589B8566C8E59E11A65F" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_endp_AccruedLiabilitiesRebates_25062B231706589B8566C8E59E11A65F" xlink:to="lab_endp_AccruedLiabilitiesRebates_25062B231706589B8566C8E59E11A65F" xlink:type="arc" />
    <link:label id="lab_endp_AccruedLiabilitiesChargebacks_4217A7D1594587CBDFE269023BC54D37_terseLabel_en-US" xlink:label="lab_endp_AccruedLiabilitiesChargebacks_EACE9ADC202C5B5D860C9E3E2FD08218" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Chargebacks</link:label>
    <link:label id="lab_endp_AccruedLiabilitiesChargebacks_4217A7D1594587CBDFE269023BC54D37_label_en-US" xlink:label="lab_endp_AccruedLiabilitiesChargebacks_EACE9ADC202C5B5D860C9E3E2FD08218" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Accrued Liabilities Chargebacks</link:label>
    <link:label id="lab_endp_AccruedLiabilitiesChargebacks_4217A7D1594587CBDFE269023BC54D37_documentation_en-US" xlink:label="lab_endp_AccruedLiabilitiesChargebacks_EACE9ADC202C5B5D860C9E3E2FD08218" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Accrued liabilities chargebacks.</link:label>
    <link:loc xlink:href="endp-20200331.xsd#endp_AccruedLiabilitiesChargebacks" xlink:label="loc_endp_AccruedLiabilitiesChargebacks_EACE9ADC202C5B5D860C9E3E2FD08218" xlink:type="locator" />
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    <link:label id="lab_us-gaap_InterestPayableCurrent_CFD8E56547531F739B6569023BC5AFBE_terseLabel_en-US" xlink:label="lab_us-gaap_InterestPayableCurrent_7B97E931EB4A58F98752892A6D83496F" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Accrued interest</link:label>
    <link:label id="lab_us-gaap_InterestPayableCurrent_CFD8E56547531F739B6569023BC5AFBE_label_en-US" xlink:label="lab_us-gaap_InterestPayableCurrent_7B97E931EB4A58F98752892A6D83496F" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Interest Payable, Current</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_InterestPayableCurrent" xlink:label="loc_us-gaap_InterestPayableCurrent_7B97E931EB4A58F98752892A6D83496F" xlink:type="locator" />
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    <link:label id="lab_us-gaap_AccruedEmployeeBenefitsCurrent_18C5F2FE736F6A1882E369023BC65B00_terseLabel_en-US" xlink:label="lab_us-gaap_AccruedEmployeeBenefitsCurrent_8306F207BE815095B9580157E25B1914" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Accrued payroll and related benefits</link:label>
    <link:label id="lab_us-gaap_AccruedEmployeeBenefitsCurrent_18C5F2FE736F6A1882E369023BC65B00_label_en-US" xlink:label="lab_us-gaap_AccruedEmployeeBenefitsCurrent_8306F207BE815095B9580157E25B1914" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Accrued Employee Benefits, Current</link:label>
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    <link:label id="lab_endp_AccruedRoyaltiesandOtherDistributionPartnerPayablesCurrent_5F2862E0E362CA3B4EC969023BC6F742_terseLabel_en-US" xlink:label="lab_endp_AccruedRoyaltiesandOtherDistributionPartnerPayablesCurrent_07BFE47D6D3E5B16B8A7F3B94B5F677F" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Accrued royalties and other distribution partner payables</link:label>
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    <link:label id="lab_us-gaap_OperatingLeasePayments_1616F001FCAB26292560E02FAC344E8C_label_en-US" xlink:label="lab_us-gaap_OperatingLeasePayments_1616F001FCAB26292560E02FAC344E8C" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Operating Lease, Payments</link:label>
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    <link:label id="lab_us-gaap_FinanceLeaseInterestPaymentOnLiability_3382506000E214803E97E02FAC34CCDA_terseLabel_en-US" xlink:label="lab_us-gaap_FinanceLeaseInterestPaymentOnLiability_3382506000E214803E97E02FAC34CCDA" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Operating cash payments for finance leases</link:label>
    <link:label id="lab_us-gaap_FinanceLeaseInterestPaymentOnLiability_3382506000E214803E97E02FAC34CCDA_label_en-US" xlink:label="lab_us-gaap_FinanceLeaseInterestPaymentOnLiability_3382506000E214803E97E02FAC34CCDA" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Finance Lease, Interest Payment on Liability</link:label>
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    <link:label id="lab_us-gaap_FinanceLeasePrincipalPayments_805A5D1456D6E43C98CBE02FAC345242_label_en-US" xlink:label="lab_us-gaap_FinanceLeasePrincipalPayments_805A5D1456D6E43C98CBE02FAC345242" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Finance Lease, Principal Payments</link:label>
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    <link:label id="lab_us-gaap_StatementOfCashFlowsAbstract_5E5574ECCCB490135016A871507D74E3_label_en-US" xlink:label="lab_us-gaap_StatementOfCashFlowsAbstract_5E5574ECCCB490135016A871507D74E3" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Statement of Cash Flows [Abstract]</link:label>
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    <link:label id="lab_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_97C2CAE93CD56F57DA90A87150891136_totalLabel_en-US" xlink:label="lab_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_97C2CAE93CD56F57DA90A87150891136" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xml:lang="en-US">NET INCREASE (DECREASE) IN CASH, CASH EQUIVALENTS, RESTRICTED CASH AND RESTRICTED CASH EQUIVALENTS</link:label>
    <link:label id="lab_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_97C2CAE93CD56F57DA90A87150891136_label_en-US" xlink:label="lab_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_97C2CAE93CD56F57DA90A87150891136" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect</link:label>
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    <link:label id="lab_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_A813033EA5A91B5E2AFCA8715089EB31_periodStartLabel_en-US" xlink:label="lab_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_A813033EA5A91B5E2AFCA8715089EB31" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel" xlink:type="resource" xml:lang="en-US">CASH, CASH EQUIVALENTS, RESTRICTED CASH AND RESTRICTED CASH EQUIVALENTS, BEGINNING OF PERIOD</link:label>
    <link:label id="lab_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_A813033EA5A91B5E2AFCA8715089EB31_label_en-US" xlink:label="lab_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_A813033EA5A91B5E2AFCA8715089EB31" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_A813033EA5A91B5E2AFCA8715089EB31" xlink:type="locator" />
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    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_B88490B1905F3DDCCBEAA87150898256" xlink:type="locator" />
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    <link:label id="lab_us-gaap_SupplementalCashFlowInformationAbstract_CAE9C878F2A5A35C4061A8715089BF50_terseLabel_en-US" xlink:label="lab_us-gaap_SupplementalCashFlowInformationAbstract_CAE9C878F2A5A35C4061A8715089BF50" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">SUPPLEMENTAL INFORMATION:</link:label>
    <link:label id="lab_us-gaap_SupplementalCashFlowInformationAbstract_CAE9C878F2A5A35C4061A8715089BF50_label_en-US" xlink:label="lab_us-gaap_SupplementalCashFlowInformationAbstract_CAE9C878F2A5A35C4061A8715089BF50" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Supplemental Cash Flow Information [Abstract]</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SupplementalCashFlowInformationAbstract" xlink:label="loc_us-gaap_SupplementalCashFlowInformationAbstract_CAE9C878F2A5A35C4061A8715089BF50" xlink:type="locator" />
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    <link:label id="lab_endp_SettlementFundsAdditions_B7D840DD5F43E9A5F643A8715089CE68_verboseLabel_en-US" xlink:label="lab_endp_SettlementFundsAdditions_B7D840DD5F43E9A5F643A8715089CE68" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xml:lang="en-US">Cash paid into Qualified Settlement Funds for mesh legal settlements</link:label>
    <link:label id="lab_endp_SettlementFundsAdditions_B7D840DD5F43E9A5F643A8715089CE68_label_en-US" xlink:label="lab_endp_SettlementFundsAdditions_B7D840DD5F43E9A5F643A8715089CE68" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Settlement Funds, Additions</link:label>
    <link:label id="lab_endp_SettlementFundsAdditions_B7D840DD5F43E9A5F643A8715089CE68_documentation_en-US" xlink:label="lab_endp_SettlementFundsAdditions_B7D840DD5F43E9A5F643A8715089CE68" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Settlement Funds, Additions</link:label>
    <link:loc xlink:href="endp-20200331.xsd#endp_SettlementFundsAdditions" xlink:label="loc_endp_SettlementFundsAdditions_B7D840DD5F43E9A5F643A8715089CE68" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_endp_SettlementFundsAdditions_B7D840DD5F43E9A5F643A8715089CE68" xlink:to="lab_endp_SettlementFundsAdditions_B7D840DD5F43E9A5F643A8715089CE68" xlink:type="arc" />
    <link:label id="lab_endp_SettlementFundsPayments_2AA0B40EF144A51804F1A871508A3D81_terseLabel_en-US" xlink:label="lab_endp_SettlementFundsPayments_2AA0B40EF144A51804F1A871508A3D81" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Cash paid out of Qualified Settlement Funds for mesh legal settlements</link:label>
    <link:label id="lab_endp_SettlementFundsPayments_2AA0B40EF144A51804F1A871508A3D81_label_en-US" xlink:label="lab_endp_SettlementFundsPayments_2AA0B40EF144A51804F1A871508A3D81" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Settlement Funds, Payments</link:label>
    <link:label id="lab_endp_SettlementFundsPayments_2AA0B40EF144A51804F1A871508A3D81_documentation_en-US" xlink:label="lab_endp_SettlementFundsPayments_2AA0B40EF144A51804F1A871508A3D81" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Settlement Funds, Payments</link:label>
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    <link:label id="lab_endp_OtherPaymentsForLegalSettlements_87E7A4148812D47CD5FFA871508A4AB5_terseLabel_en-US" xlink:label="lab_endp_OtherPaymentsForLegalSettlements_87E7A4148812D47CD5FFA871508A4AB5" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Other cash distributions for mesh legal settlements</link:label>
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    <link:label id="lab_endp_OtherPaymentsForLegalSettlements_87E7A4148812D47CD5FFA871508A4AB5_documentation_en-US" xlink:label="lab_endp_OtherPaymentsForLegalSettlements_87E7A4148812D47CD5FFA871508A4AB5" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Other Payments For Legal Settlements</link:label>
    <link:loc xlink:href="endp-20200331.xsd#endp_OtherPaymentsForLegalSettlements" xlink:label="loc_endp_OtherPaymentsForLegalSettlements_87E7A4148812D47CD5FFA871508A4AB5" xlink:type="locator" />
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    <link:label id="lab_us-gaap_OperatingLeaseCost_551B30A8A60601645F6A54F073CCE9E5_terseLabel_en-US" xlink:label="lab_us-gaap_OperatingLeaseCost_551B30A8A60601645F6A54F073CCE9E5" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Operating lease cost</link:label>
    <link:label id="lab_us-gaap_OperatingLeaseCost_551B30A8A60601645F6A54F073CCE9E5_label_en-US" xlink:label="lab_us-gaap_OperatingLeaseCost_551B30A8A60601645F6A54F073CCE9E5" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Operating Lease, Cost</link:label>
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    <link:label id="lab_us-gaap_LeaseCostAbstract_07AEA8D7B7B46626FD5754F073CDFBCB_verboseLabel_en-US" xlink:label="lab_us-gaap_LeaseCostAbstract_07AEA8D7B7B46626FD5754F073CDFBCB" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xml:lang="en-US">Finance lease cost:</link:label>
    <link:label id="lab_us-gaap_LeaseCostAbstract_07AEA8D7B7B46626FD5754F073CDFBCB_label_en-US" xlink:label="lab_us-gaap_LeaseCostAbstract_07AEA8D7B7B46626FD5754F073CDFBCB" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Lease, Cost [Abstract]</link:label>
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    <link:label id="lab_us-gaap_FinanceLeaseInterestExpense_56E8D937B6111C28107254F073CD48C6_label_en-US" xlink:label="lab_us-gaap_FinanceLeaseInterestExpense_56E8D937B6111C28107254F073CD48C6" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Finance Lease, Interest Expense</link:label>
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    <link:label id="lab_srt_ConsolidationItemsAxis_149BE95FDCB089241596C20314124896_label_en-US" xlink:label="lab_srt_ConsolidationItemsAxis_149BE95FDCB089241596C20314124896" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Consolidation Items [Axis]</link:label>
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    <link:label id="lab_srt_ConsolidationItemsDomain_9002A71CF2511CE2ED69C20314124378_label_en-US" xlink:label="lab_srt_ConsolidationItemsDomain_9002A71CF2511CE2ED69C20314124378" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Consolidation Items [Domain]</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_ConsolidationItemsDomain" xlink:label="loc_srt_ConsolidationItemsDomain_9002A71CF2511CE2ED69C20314124378" xlink:type="locator" />
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    <link:label id="lab_us-gaap_MaterialReconcilingItemsMember_0CE03C27A905E80D5D79C2031413D561_label_en-US" xlink:label="lab_us-gaap_MaterialReconcilingItemsMember_0CE03C27A905E80D5D79C2031413D561" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Segment Reconciling Items [Member]</link:label>
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    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OperatingSegmentsMember" xlink:label="loc_us-gaap_OperatingSegmentsMember_D8F31784741B1CC44583C2031413044B" xlink:type="locator" />
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    <link:label id="lab_us-gaap_RestructuringCostAndReserveAxis_CE2DCDBCDB89D908629BC20314134E64_label_en-US" xlink:label="lab_us-gaap_RestructuringCostAndReserveAxis_CE2DCDBCDB89D908629BC20314134E64" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Restructuring Type [Axis]</link:label>
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